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Original Articles

Comparison of Robust Criteria for D-Optimal Designs

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Pages 1193-1205 | Received 12 Dec 2010, Accepted 09 Apr 2011, Published online: 17 Oct 2012

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Read on this site (3)

Florence Loingeville, Thu Thuy Nguyen, Marie-Karelle Riviere & France Mentré. (2020) Robust designs in longitudinal studies accounting for parameter and model uncertainties – application to count data. Journal of Biopharmaceutical Statistics 30:1, pages 31-45.
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Matthew S. Shotwell, Minchun Zhou & William H. Fissell. (2016) Optimal design of perturbations for individual two-compartment pharmacokinetic analysis. Journal of Biopharmaceutical Statistics 26:5, pages 803-815.
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Cyrielle Dumont, Marylore Chenel & France Mentré. (2016) Two-stage Adaptive Designs in Nonlinear Mixed Effects Models: Application to Pharmacokinetics in Children. Communications in Statistics - Simulation and Computation 45:5, pages 1511-1525.
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Articles from other publishers (7)

Lucie Fayette, Romain Leroux, France Mentré & Jérémy Seurat. (2023) Robust and Adaptive Two-stage Designs in Nonlinear Mixed Effect Models. The AAPS Journal 25:4.
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Jérémy Seurat, Thu Thuy Nguyen & France Mentré. (2019) Robust designs accounting for model uncertainty in longitudinal studies with binary outcomes. Statistical Methods in Medical Research 29:3, pages 934-952.
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Cyrielle Dumont, Giulia Lestini, Hervé Le Nagard, France Mentré, Emmanuelle Comets, Thu Thuy Nguyen & for the PFIM group. (2018) PFIM 4.0, an extended R program for design evaluation and optimization in nonlinear mixed-effect models. Computer Methods and Programs in Biomedicine 156, pages 217-229.
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Stephen B. Duffull & Andrew C. Hooker. (2017) Assessing robustness of designs for random effects parameters for nonlinear mixed-effects models. Journal of Pharmacokinetics and Pharmacodynamics 44:6, pages 611-616.
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Thu Thuy Nguyen, Henri Bénech, Marcel Delaforge & Natacha Lenuzza. (2016) Design optimisation for pharmacokinetic modeling of a cocktail of phenotyping drugs. Pharmaceutical Statistics 15:2, pages 165-177.
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Giulia Lestini, Cyrielle Dumont & France Mentré. (2015) Influence of the Size of Cohorts in Adaptive Design for Nonlinear Mixed Effects Models: An Evaluation by Simulation for a Pharmacokinetic and Pharmacodynamic Model for a Biomarker in Oncology. Pharmaceutical Research 32:10, pages 3159-3169.
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Vidya Perera, Robert R. Bies, Gary Mo, Michael J. Dolton, Vaughan J. Carr, Andrew J. McLachlan, Richard O. Day, Thomas M. Polasek & Alan Forrest. (2014) Optimal sampling of antipsychotic medicines: a pharmacometric approach for clinical practice. British Journal of Clinical Pharmacology 78:4, pages 800-814.
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