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Journal of Biopharmaceutical Statistics Volume 23, 2013 - Issue 5
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Original Articles

Optimal Timing for Interim Analyses in Clinical Trials

Kanae Togo Clinical Statistics, Pfizer Japan, Inc., Tokyo, JapanCorrespondence[email protected]
&
Manabu Iwasaki Science and Technology, Seikei University, Tokyo, Japan
Pages 1067-1080 | Received 01 Nov 2011, Accepted 16 May 2012, Published online: 19 Aug 2013

Citations (15)

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Read on this site (5)

Bo Feng & Benny Zee. (2023) Robust time selection for interim analysis in the Bayesian phase 2 exploratory clinical trial. Journal of Biopharmaceutical Statistics 0:0, pages 1-11.
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Xinyu Tang, Lihan K. Yan & John A. Scott. (2022) Conditional power in vaccine trials with seasonal variations. Journal of Biopharmaceutical Statistics 32:3, pages 427-440.
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Shogo Nomura. (2021) Sample Size Determination in Group-Sequential Trials Assessing Interim Futility by Intermediate Composite Endpoints. Statistics in Biopharmaceutical Research 13:4, pages 492-503.
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Koko Asakura, Scott R. Evans & Toshimitsu Hamasaki. (2020) Interim Monitoring for Futility in Clinical Trials With Two Co-Primary Endpoints Using Prediction. Statistics in Biopharmaceutical Research 12:2, pages 164-175.
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Dong Xi, Paul Gallo & David Ohlssen. (2017) On the Optimal Timing of Futility Interim Analyses. Statistics in Biopharmaceutical Research 9:3, pages 293-301.
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Articles from other publishers (10)

Michael J. Grayling & Adrian P. Mander. (2021) Accounting for variation in the required sample size in the design of group-sequential trials. Contemporary Clinical Trials 107, pages 106459.
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Munyaradzi Dimairo, Philip Pallmann, James Wason, Susan Todd, Thomas Jaki, Steven A. Julious, Adrian P. Mander, Christopher J. Weir, Franz Koenig, Marc K. Walton, Jon P. Nicholl, Elizabeth Coates, Katie Biggs, Toshimitsu Hamasaki, Michael A. Proschan, John A. Scott, Yuki Ando, Daniel Hind, Douglas G. Altman, Munyaradzi Dimairo, Toshimitsu Hamasaki, Susan Todd, Christopher J. Weir, Adrian P. Mander, James Wason, Franz Koenig, Steven A. Julious, Daniel Hind, Jon Nicholl, Douglas G. Altman, William J. Meurer, Christopher Cates, Matthew Sydes, Yannis Jemiai, Deborah Ashby, Christina Yap, Frank Waldron-Lynch, James Roger, Joan Marsh, Olivier Collignon, David J. Lawrence, Catey Bunce, Tom Parke, Gus Gazzard, Elizabeth Coates, Marc K. Walton, Sally Hopewell, Philip Pallmann, Thomas Jaki, Katie Biggs, Michael A. Proschan, John A. Scott & Yuki Ando. (2020) The adaptive designs CONSORT extension (ACE) statement: a checklist with explanation and elaboration guideline for reporting randomised trials that use an adaptive design. Trials 21:1.
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Elizabeth G. Ryan, Kristian Brock, Simon Gates & Daniel Slade. (2020) Do we need to adjust for interim analyses in a Bayesian adaptive trial design?. BMC Medical Research Methodology 20:1.
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Munyaradzi Dimairo, Philip Pallmann, James Wason, Susan Todd, Thomas Jaki, Steven A Julious, Adrian P Mander, Christopher J Weir, Franz Koenig, Marc K Walton, Jon P Nicholl, Elizabeth Coates, Katie Biggs, Toshimitsu Hamasaki, Michael A Proschan, John A Scott, Yuki Ando, Daniel Hind & Douglas G Altman. (2020) The Adaptive designs CONSORT Extension (ACE) statement: a checklist with explanation and elaboration guideline for reporting randomised trials that use an adaptive design. BMJ, pages m115.
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Xiao Wu, Yi Xu & Bradley P. Carlin. (2019) Optimizing interim analysis timing for Bayesian adaptive commensurate designs. Statistics in Medicine 39:4, pages 424-437.
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James Normington, Jiawen Zhu, Federico Mattiello, Somnath Sarkar & Brad Carlin. (2020) An efficient Bayesian platform trial design for borrowing adaptively from historical control data in lymphoma. Contemporary Clinical Trials 89, pages 105890.
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Ryuji Uozumi, Shinjo Yada & Atsushi Kawaguchi. (2019) Patient recruitment strategies for adaptive enrichment designs with time-to-event endpoints. BMC Medical Research Methodology 19:1.
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Jongphil Kim & Michael J. Schell. (2019) Modified Simon’s minimax and optimal two-stage designs for single-arm phase II cancer clinical trials. Oncotarget 10:42, pages 4255-4261.
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Kim Chau & Gideon Koren. (2014) The Principle of Equipoise in Pediatric Drug Trials. Pediatric Drugs 17:1, pages 17-21.
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Sameer Parpia, Jim A Julian, Chushu Gu, Lehana Thabane & Mark N Levine. (2014) Interim analysis for binary outcome trials with a long fixed follow-up time and repeated outcome assessments at pre-specified times. SpringerPlus 3:1.
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