Estimating the subgroup and testing for treatment effect in a post-hoc analysis of a clinical trial with a biomarker

Neha JoshiDepartment of Biostatistics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USAView further author information

Jason FineDepartment of Biostatistics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USAView further author information

Rong ChuBiostatistics, Agensys, Inc, Santa Monica, CA, USAView further author information

Anastasia IvanovaDepartment of Biostatistics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USACorrespondence[email protected]
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Neha Joshi, Crystal Nguyen & Anastasia Ivanova. (2020) Multi-stage adaptive enrichment trial design with subgroup estimation. Journal of Biopharmaceutical Statistics 30:6, pages 1038-1049.
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Anastasia Ivanova, Elliot Israel, Lisa M. LaVange, Michael C. Peters, Loren C. Denlinger, Wendy C. Moore, Leonard B. Bacharier, M. Alison Marquis, Nathan M. Gotman, Michael R. Kosorok, Chalmer Tomlinson, David T. Mauger, Steve N. Georas, Rosalind J. Wright, Patricia Noel, Gary L. Rosner, Praveen Akuthota, Dean Billheimer, Eugene R. Bleecker, Juan Carlos Cardet, Mario Castro, Emily A. DiMango, Serpil C. Erzurum, John V. Fahy, Merritt L. Fajt, Benjamin M. Gaston, Fernando Holguin, Sonia Jain, Nicholas J. Kenyon, Jerry A. Krishnan, Monica Kraft, Rajesh Kumar, Mark C. Liu, Ngoc P. Ly, James N. Moy, Wanda Phipatanakul, Kristie Ross, Lewis J. Smith, Stanley J. Szefler, W. Gerald Teague, Michael E. Wechsler, Sally E. Wenzel & Steven R. White. (2020) The precision interventions for severe and/or exacerbation-prone asthma (PrecISE) adaptive platform trial: statistical considerations. Journal of Biopharmaceutical Statistics 30:6, pages 1026-1037.
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Articles from other publishers (2)

Beibo Zhao, Anastasia Ivanova & Jason Fine. (2023) Inference on subgroups identified based on a heterogeneous treatment effect in a post hoc analysis of a clinical trial. Clinical Trials 20:4, pages 370-379.
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Yifei Sun, Xuming He & Jianhua Hu. (2022) An omnibus test for detection of subgroup treatment effects via data partitioning. The Annals of Applied Statistics 16:4.
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Estimating the subgroup and testing for treatment effect in a post-hoc analysis of a clinical trial with a biomarker

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Estimating the subgroup and testing for treatment effect in a post-hoc analysis of a clinical trial with a biomarker

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