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Journal of Biopharmaceutical Statistics Volume 8, 1998 - Issue 2
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Original Articles

Estimating treatment effects in clinical crossover trials

Andrew Grieve Pfizer, Sandwich, UK
&
Stephen Senn Department of Statistical Science and Department of Epidemiology and Community Health, University College London, Gower Street, London, WC1E6BT, UK
Pages 191-233 | Published online: 29 Mar 2007

Citations (21)

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Read on this site (4)

Ijaz Iqbal, M. H. Tahir & Syed Skahir Ali Ghazali. (2009) Circular First- and Second-Order Balanced Repeated Measurements Designs. Communications in Statistics - Theory and Methods 39:2, pages 228-240.
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Nancy D. Smith. (1998) Discussion of “estimating treatment effects in clinical crossover trials”: A Regulatory perspective . Journal of Biopharmaceutical Statistics 8:2, pages 243-247.
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Gary G. Koch. (1998) Discussion of “estimating treatment effects in clinical crossover trials”. Journal of Biopharmaceutical Statistics 8:2, pages 239-242.
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Byron Jones & Jixian Wang. (1998) Comments on “estimating treatment effects in clinical crossover trials”. Journal of Biopharmaceutical Statistics 8:2, pages 235-238.
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Articles from other publishers (17)

Stephen Senn. (2022) The design and analysis of vaccine trials for COVID ‐19 for the purpose of estimating efficacy . Pharmaceutical Statistics 21:4, pages 790-807.
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Stephen Senn. (2022) Viewpoint : Do not resurrect the two‐stage procedure . Pharmaceutical Statistics 21:4, pages 808-814.
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Quan Zhang, Youssef Toubouti & Bradley P Carlin. (2015) Design and analysis of Bayesian adaptive crossover trials for evaluating contact lens safety and efficacy. Statistical Methods in Medical Research 26:3, pages 1216-1236.
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Andrew P. Grieve. (2017) Response-adaptive clinical trials: case studies in the medical literature. Pharmaceutical Statistics 16:1, pages 64-86.
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Stephen Senn. 2012. Encyclopedia of Biopharmaceutical Statistics, Third Edition. Encyclopedia of Biopharmaceutical Statistics, Third Edition 380 385 .
M Rashid. 2012. Encyclopedia of Biopharmaceutical Statistics, Third Edition. Encyclopedia of Biopharmaceutical Statistics, Third Edition 1114 1124 .
Nicola S. Anstice & John R. Phillips. (2011) Effect of Dual-Focus Soft Contact Lens Wear on Axial Myopia Progression in Children. Ophthalmology 118:6, pages 1152-1161.
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Shein-Chung ChowM.Mushfiqur Rashid. 2010. Encyclopedia of Biopharmaceutical Statistics. Encyclopedia of Biopharmaceutical Statistics 1114 1124 .
Shein-Chung ChowStephen Senn. 2010. Encyclopedia of Biopharmaceutical Statistics. Encyclopedia of Biopharmaceutical Statistics 380 385 .
Andrew P. Grieve. (2007) 25 years of Bayesian methods in the pharmaceutical industry: a personal, statistical bummel. Pharmaceutical Statistics 6:4, pages 261-281.
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S. S. Lund, L. Tarnow, C. D. A. Stehouwer, C. G. Schalkwijk, M. Frandsen, U. M. Smidt, O. Pedersen, H.-H. Parving & A. Vaag. (2007) Targeting hyperglycaemia with either metformin or repaglinide in non-obese patients with type 2 diabetes: results from a randomized crossover trial. Diabetes, Obesity and Metabolism 9:3, pages 394-407.
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N. T. Longford. (2005) Editorial: Model Selection and Efficiency—is ‘Which Model …?’ the Right Question?. Journal of the Royal Statistical Society Series A: Statistics in Society 168:3, pages 469-472.
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Stephen Senn, Giuseppina D'Angelo & Diane Potvin. (2004) Carry‐over in cross‐over trials in bioequivalence: theoretical concerns and empirical evidence. Pharmaceutical Statistics 3:2, pages 133-142.
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M Rashid. 2003. Encyclopedia of Biopharmaceutical Statistics, Second edition. Encyclopedia of Biopharmaceutical Statistics, Second edition 870 883 .
Ramón Dı́az-Uriarte. (2002) Incorrect analysis of crossover trials in animal behaviour research. Animal Behaviour 63:4, pages 815-822.
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Nicholas T. Longford. (2001) Synthetic estimators with moderating influence: the carry‐over in cross‐over trials revisited. Statistics in Medicine 20:21, pages 3189-3203.
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Stephen Senn. (2001) Cross-over trials in drug development: theory and practice. Journal of Statistical Planning and Inference 96:1, pages 29-40.
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