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Original Articles

Advanced Urine Toxicology Testing

Pages 436-448 | Published online: 05 Oct 2010

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Marco Cavicchioli, Mariagrazia Movalli, Pietro Ramella, Giulia Vassena, Francesca Prudenziati & Cesare Maffei. (2020) Feasibility of dialectical behavior therapy skills training as an outpatient program in treating alcohol use disorder: The role of difficulties with emotion regulation and experiential avoidance. Addiction Research & Theory 28:2, pages 103-115.
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Hong K. Kim, Nicholas J. Connors & Maryann E. Mazer-Amirshahi. (2019) The role of take-home naloxone in the epidemic of opioid overdose involving illicitly manufactured fentanyl and its analogs. Expert Opinion on Drug Safety 18:6, pages 465-475.
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Luke K. Wiseman & Mary E. Lynch. (2018) The utility of universal urinary drug screening in chronic pain management. Canadian Journal of Pain 2:1, pages 37-47.
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Articles from other publishers (61)

Ming-Chyi Huang, Su-Chen Fang, Chun Lin, Ta Lin, Hu-Ming Chang, Tien-Wei Yang & Lian-Yu Chen. (2023) Risk factors for relapse among methamphetamine users receiving a joint legal–medical treatment program as a diversion intervention: A one-year follow-up study. Journal of Substance Use and Addiction Treatment 151, pages 208955.
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Bharathi Avula, Kumar Katragunta, Sebastian John Adams, Yan-Hong Wang, Amar G. Chittiboyina & Ikhlas A. Khan. (2023) Applicability of LC-QToF and Microscopical Tools in Combating the Sophisticated, Economically Motivated Adulteration of Poppy Seeds. Foods 12:7, pages 1510.
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K H Brian Lam, Tim Sobolevsky, Brian Ahrens, Lu Song & Imir G Metushi. (2023) A Suspected Case of Carbon Monoxide Poisoning Consistent with Fentanyl Toxicity. The Journal of Applied Laboratory Medicine 8:2, pages 413-417.
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Dimitri Gerostamoulos & Jennifer Schumann. 2023. Encyclopedia of Forensic Sciences, Third Edition. Encyclopedia of Forensic Sciences, Third Edition 254 262 .
Kenneth Silverman, August F. Holtyn, Forrest Toegel & Matthew D. Novak. 2023. Handbook of Applied Behavior Analysis. Handbook of Applied Behavior Analysis 1257 1275 .
Sara Yasien, Ejaz Ali, Mohsin Javed, Muhammad Muntazir Iqbal, Shahid Iqbal, Hamad Alrbyawi, Samar O. Aljazzar, Eslam B. Elkaeed, Ayed A. Dera, Rami Adel Pashameah, Eman Alzahrani & Abd-ElAziem Farouk. (2022) Simultaneous Quantification of Opioids in Blood and Urine by Gas Chromatography-Mass Spectrometer with Modified Dispersive Solid-Phase Extraction Technique. Molecules 27:19, pages 6761.
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Karen E. Butler & Erin S. Baker. (2022) A High-Throughput Ion Mobility Spectrometry–Mass Spectrometry Screening Method for Opioid Profiling. Journal of the American Society for Mass Spectrometry 33:10, pages 1904-1913.
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Gary M Reisfield, Scott A Teitelbaum & Joseph T Jones. (2022) Poppy Seed Consumption May Be Associated with Codeine-Only Urine Drug Test Results. Journal of Analytical Toxicology.
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Jamie Lewis, Karlee De Monnin, Jonathan Smith, Evan Lewis & Marian Wilson. (2021) Interpreting Urine Drug Test Results in the Context of Chronic Opioid Analgesic Therapy and Poppy Seed Consumption. Pain Medicine 22:11, pages 2776-2778.
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Marco Cavicchioli, Federico Calesella, Silvia Cazzetta, Movalli Mariagrazia, Anna Ogliari, Cesare Maffei & Benedetta Vai. (2021) Investigating predictive factors of dialectical behavior therapy skills training efficacy for alcohol and concurrent substance use disorders: A machine learning study. Drug and Alcohol Dependence 224, pages 108723.
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Rachel C Dale, Loretta T Ford & Catherine Street. (2021) Are point-of-care urine drug testing devices suitable for antenatal drug screening? A study verifying the Alere® Drug Screen Test Cup for the detection of six classes of drug in a pregnant population. Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 58:3, pages 166-173.
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Daniel J. Angelini, Tracey D. Biggs, Amber M. Prugh, Jessica A. Smith, Jennifer A. Hanburger, Bob Llano, Raquel Avelar, Angela Ellis, Brady Lusk, Abdallah Malik Naanaa, Edward Sisco & Jennifer W. Sekowski. (2020) The use of lateral flow immunoassays for the detection of fentanyl in seized drug samples and postmortem urine. Journal of Forensic Sciences 66:2, pages 758-765.
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Tiffany Lu & Chinazo Cunningham. 2021. Treating Opioid Use Disorder in General Medical Settings. Treating Opioid Use Disorder in General Medical Settings 23 42 .
Samuel J. Stellpflug, Jon B. Cole & Howard A. Greller. (2020) Urine Drug Screens in the Emergency Department: The Best Test May Be No Test at All. Journal of Emergency Nursing 46:6, pages 923-931.
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Karim M. Soliman, Christopher Molini, Tessa Novick, Steven Menez, Tibor Fülöp, Edward Kraus & Blaithin A. McMahon. (2020) The impact of donor urine chemical toxicology analysis on outcomes of kidney transplantation. International Urology and Nephrology 52:6, pages 1173-1178.
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Amitava Dasgupta & Matthew D. Krasowski. 2020. Therapeutic Drug Monitoring Data. Therapeutic Drug Monitoring Data 91 98 .
Barbara St. Marie. (2019) Assessing Patients’ Risk for Opioid Use Disorder. AACN Advanced Critical Care 30:4, pages 343-352.
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Marco Cavicchioli, Mariagrazia Movalli, Giulia Vassena, Pietro Ramella, Francesca Prudenziati & Cesare Maffei. (2019) The therapeutic role of emotion regulation and coping strategies during a stand-alone DBT Skills training program for alcohol use disorder and concurrent substance use disorders. Addictive Behaviors 98, pages 106035.
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Anna Ferrari, Cecilia Rustichelli, Carlo Baraldi, Daniele Vandelli, Patrizia Verri, Filippo Marchesi & Manuela Licata. (2019) Intra‐patient variability of the hair levels of pain medications in chronic migraine patients – a pilot study. Drug Testing and Analysis 11:6, pages 878-885.
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Michael Böttcher, Stefan Lierheimer, Andreas Peschel & Olof Beck. (2019) Detection of heroin intake in patients in substitution treatment using oral fluid as specimen for drug testing. Drug and Alcohol Dependence 198, pages 136-139.
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PATRICIA OVERCARSH, LARA HARVEY & AMANDA YUNKER. (2019) Guidelines for Monitoring Patients Using Opioid Therapy. Clinical Obstetrics & Gynecology 62:1, pages 59-66.
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Fabian Picht, Olof Beck & Michael Böttcher. (2019) Evaluation of an on‐site test device for the heroin metabolite 6‐acetylmorphine in urine. Drug Testing and Analysis 11:3, pages 536-540.
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Matthew D. Krasowski & Tai C. Kwong. 2019. Critical Issues in Alcohol and Drugs of Abuse Testing. Critical Issues in Alcohol and Drugs of Abuse Testing 441 448 .
Jessica M. Boyd & S.M. Hossein Sadrzadeh. 2019. Accurate Results in the Clinical Laboratory. Accurate Results in the Clinical Laboratory 233 242 .
Lisa Boyars & Constance Guille. (2018) Treatment of Perinatal Opioid Use Disorder. Obstetrics and Gynecology Clinics of North America 45:3, pages 511-524.
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Justine M. Reschly-Krasowski & Matthew D. Krasowski. (2018) A Difficult Challenge for the Clinical Laboratory: Accessing and Interpreting Manufacturer Cross-Reactivity Data for Immunoassays Used in Urine Drug Testing. Academic Pathology 5, pages 2374289518811797.
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Charles E Argoff, Daniel P Alford, Jeffrey Fudin, Jeremy A Adler, Matthew J Bair, Richard C Dart, Roy Gandolfi, Bill H McCarberg, Steven P Stanos, Jeffrey A Gudin, Rosemary C Polomano & Lynn R Webster. (2018) Rational Urine Drug Monitoring in Patients Receiving Opioids for Chronic Pain: Consensus Recommendations. Pain Medicine 19:1, pages 97-117.
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Michelle R. Lofwall & Amy M. Yule. 2018. Adolescent Substance Abuse. Adolescent Substance Abuse 215 231 .
Matthew P. Prekupec, Peter A. Mansky & Michael H. Baumann. (2017) Misuse of Novel Synthetic Opioids: A Deadly New Trend. Journal of Addiction Medicine 11:4, pages 256-265.
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Daniel A. Schwarz, M.P. George & Martin H. Bluth. (2016) Toxicology in Addiction Medicine. Clinics in Laboratory Medicine 36:4, pages 685-692.
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Tricia E. Wright, Mishka Terplan, Steven J. Ondersma, Cheryl Boyce, Kimberly Yonkers, Grace Chang & Andreea A. Creanga. (2016) The role of screening, brief intervention, and referral to treatment in the perinatal period. American Journal of Obstetrics and Gynecology 215:5, pages 539-547.
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Zachary J. Nelson, Samuel J. Stellpflug & Kristin M. Engebretsen. (2016) What Can a Urine Drug Screening Immunoassay Really Tell Us?. Journal of Pharmacy Practice 29:5, pages 516-526.
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R. Brent Dixon, Bonnette Davis & Amitava Dasgupta. (2016) Comparison of Response of DRI Oxycodone Semiquantitative Immunoassay With True Oxycodone Values Determined by Liquid Chromatography Combined With Tandem Mass Spectrometry: Sensitivity of the DRI Assay at 100 ng/ml Cut-Off and Validity of Semiquantitative. Journal of Clinical Laboratory Analysis 30:3, pages 190-195.
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Joanna Starrels & Jennifer McNeely. 2016. Chronic Pain and HIV. Chronic Pain and HIV 123 136 .
Kamisha L. Johnson-Davis, Aaron J. Sadler & Jonathan R. Genzen. (2016) A Retrospective Analysis of Urine Drugs of Abuse Immunoassay True Positive Rates at a National Reference Laboratory. Journal of Analytical Toxicology 40:2, pages 97-107.
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Mira Sundström, Anna Pelander, Kaarlo Simojoki & Ilkka Ojanperä. (2016) Patterns of drug abuse among drug users with regular and irregular attendance for treatment as detected by comprehensive UHPLC-HR-TOF-MS. Drug Testing and Analysis 8:1, pages 39-45.
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Mira Sundström, Anna Pelander & Ilkka Ojanperä. (2015) Comparison between drug screening by immunoassay and ultra-high performance liquid chromatography/high-resolution time-of-flight mass spectrometry in post-mortem urine. Drug Testing and Analysis 7:5, pages 420-427.
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Matthew D. Krasowski, Andy Schriever, Gagan Mathur, John L. Blau, Stephanie L. Stauffer & Bradley A. Ford. (2015) Use of a data warehouse at an academic medical center for clinical pathology quality improvement, education, and research. Journal of Pathology Informatics 6:1, pages 45.
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Joyce Ho. 2015. Pain Management and Palliative Care. Pain Management and Palliative Care 37 44 .
Matthew D Krasowski & Sean Ekins. (2014) Using cheminformatics to predict cross reactivity of “designer drugs” to their currently available immunoassays. Journal of Cheminformatics 6:1.
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Jason A. Gregg & Jill S. Jones. (2014) What Clinical Practice Strategies Can Be Utilized to Help Reduce the Incidence of Heroin Abuse in Rehabilitation Patients on Chronic Opioid Therapy?. Rehabilitation Nursing 39:6, pages 281-284.
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Setu Kasera, Lars O. Herrmann, Jesús del Barrio, Jeremy J. Baumberg & Oren A. Scherman. (2014) Quantitative multiplexing with nano-self-assemblies in SERS. Scientific Reports 4:1.
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Kenneth Blum, David Han, John Femino, David E. Smith, Scott Saunders, Thomas Simpatico, Stephen J. Schoenthaler, Marlene Oscar-Berman & Mark S. Gold. (2014) Systematic Evaluation of “Compliance” to Prescribed Treatment Medications and “Abstinence” from Psychoactive Drug Abuse in Chemical Dependence Programs: Data from the Comprehensive Analysis of Reported Drugs. PLoS ONE 9:9, pages e104275.
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François Versace, Julien Déglon, Patrice Mangin & Christian Staub. (2014) Application of direct-infusion ESI–MS/MS for toxicological screening. Bioanalysis 6:15, pages 2043-2055.
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Giuseppe Lippi, Diego Ardissino, Roberto Quintavalla & Gianfranco Cervellin. (2014) Urgent monitoring of direct oral anticoagulants in patients with atrial fibrillation: a tentative approach based on routine laboratory tests. Journal of Thrombosis and Thrombolysis 38:2, pages 269-274.
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Maria Andersson, Nikolai Stephanson, Inger Öhman, Tommy Terzuoli, Jonatan D Lindh & Olof Beck. (2014) Direct and efficient liquid chromatographic-tandem mass spectrometric method for opiates in urine drug testing - importance of 6-acetylmorphine and reduction of analytes. Drug Testing and Analysis 6:4, pages 317-324.
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Judith A. Turner, Kathleen Saunders, Susan M. Shortreed, Suzanne E. Rapp, Stephen Thielke, Linda LeResche, Kim M. Riddell & Michael Von Korff. (2013) Chronic Opioid Therapy Risk Reduction Initiative: Impact on Urine Drug Testing Rates and Results. Journal of General Internal Medicine 29:2, pages 305-311.
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Claire E. Wilcox, Michael P. Bogenschutz, Masato Nakazawa & George Woody. (2013) Concordance between self-report and urine drug screen data in adolescent opioid dependent clinical trial participants. Addictive Behaviors 38:10, pages 2568-2574.
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Alkesh N. Patel. (2013) Addiction in Chronic Pain Patients: Evidence-Based Approaches for Monitoring Chronic Opioid Therapy. Psychiatric Annals 43:9, pages 403-407.
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Hans H. Maurer. (2013) What is the future of (ultra) high performance liquid chromatography coupled to low and high resolution mass spectrometry for toxicological drug screening?. Journal of Chromatography A 1292, pages 19-24.
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Joanna L. Starrels, Aaron D. Fox, Hillary V. Kunins & Chinazo O. Cunningham. (2012) They Don’t Know What They Don’t Know: Internal Medicine Residents’ Knowledge and Confidence in Urine Drug Test Interpretation for Patients with Chronic Pain. Journal of General Internal Medicine 27:11, pages 1521-1527.
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Ilkka Ojanperä, Marjo Kolmonen & Anna Pelander. (2012) Current use of high-resolution mass spectrometry in drug screening relevant to clinical and forensic toxicology and doping control. Analytical and Bioanalytical Chemistry 403:5, pages 1203-1220.
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G. A. McMillin, R. Davis, H. Carlisle, C. Clark, S. J. Marin & D. E. Moody. (2012) Patterns of Free (Unconjugated) Buprenorphine, Norbuprenorphine, and Their Glucuronides in Urine Using Liquid Chromatography-Tandem Mass Spectrometry. Journal of Analytical Toxicology 36:2, pages 81-87.
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Dirk K. Wissenbach, Markus R. Meyer, Armin A. Weber, Daniela Remane, Andreas H. Ewald, Frank T. Peters & Hans H. Maurer. (2012) Towards a universal LC–MS screening procedure – can an LIT LC–MS n screening approach and reference library be used on a quadrupole‐LIT hybrid instrument? . Journal of Mass Spectrometry 47:1, pages 66-71.
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Sheetal Kircher, James Zacny, Sean M. Apfelbaum, Steve Passik, Ken Kirsch, Maureen Burbage & Michelle Lofwall. (2011) Understanding and Treating Opioid Addiction in a Patient With Cancer Pain. The Journal of Pain 12:10, pages 1025-1031.
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Dirk K. Wissenbach, Markus R. Meyer, Daniela Remane, Anika A. Philipp, Armin A. Weber & Hans H. Maurer. (2011) Drugs of abuse screening in urine as part of a metabolite-based LC-MSn screening concept. Analytical and Bioanalytical Chemistry 400:10, pages 3481-3489.
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