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Original Articles

Simultaneous Removal of two 2-cyano-1,1-dimethylethyl Groups from Bis(2-cyano-1,1-dimethylethyl) Thymidine 3′-phosphate Derivatives by the Use of DBU/BSA

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Pages 41-46 | Received 01 Jun 1994, Published online: 04 Oct 2006

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Mitsuo. Sekine, Hiroyuki. Tsuruoka, Koh-ichiro. Shohda, Tomohisa. Moriguchi & Tomohisa. Wada. (1998) New Strategies for the Chemical Synthesis of Biologically Important Nucleic Acid Derivatives. Nucleosides and Nucleotides 17:9-11, pages 2033-2043.
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Natsuhisa Oka, Hiroki Hirabayashi, Kota Kumada & Kaori Ando. (2021) Synthesis of xanthosine 2-phosphate diesters via phosphitylation of the carbonyl group. Bioorganic & Medicinal Chemistry Letters 54, pages 128439.
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Kaori Ando, Hisao Saneyoshi, Kohji Seio & Mitsuo Sekine. (2019) A theoretical study on the elimination reaction of acrylonitrile from 2′-O-cyanoethylated nucleosides by Bu4NF. Tetrahedron 75:1, pages 1-9.
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. 2014. Greene's Protective Groups in Organic Synthesis. Greene's Protective Groups in Organic Synthesis 1203 1262 .
Natsuhisa Oka, Yasuhiro Morita, Yuta Itakura & Kaori Ando. (2013) Synthesis of inosine 6-phosphate diesters via phosphitylation of the carbonyl oxygen. Chemical Communications 49:98, pages 11503.
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Claudine M. Dojahn, Marlen Hesse & Christoph Arenz. (2013) A chemo-enzymatic approach to specifically click-modified RNA. Chemical Communications 49:30, pages 3128.
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Edyta Gendaszewska-Darmach, Edyta Laska, Przemys?aw Rytczak & Andrzej Okruszek. (2012) The chemical synthesis of metabolically stabilized 2-OMe-LPA analogues and preliminary studies of their inhibitory activity toward autotaxin. Bioorganic & Medicinal Chemistry Letters 22:8, pages 2698-2700.
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Seigo Nagata, Tomohiro Hamasaki, Koichi Uetake, Hirofumi Masuda, Kazuchika Takagaki, Natsuhisa Oka, Takeshi Wada, Tadaaki Ohgi & Junichi Yano. (2010) Synthesis and biological activity of artificial mRNA prepared with novel phosphorylating reagents. Nucleic Acids Research 38:21, pages 7845-7857.
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Przemysław Rytczak, Maria Koziołkiewicz & Andrzej Okruszek. (2010) The chemical synthesis of phosphorothioate and phosphorodithioate analogues of lysophosphatidic acid (LPA) and cyclic phosphatidic acid (CPA). New Journal of Chemistry 34:5, pages 1008.
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Qing Dai, Mridusmitas Saikia, Nan-Sheng Li, Tao Pan & Joseph A. Piccirilli. (2009) Efficient Chemical Synthesis of AppDNA by Adenylation of Immobilized DNA-5′-monophosphate. Organic Letters 11:5, pages 1067-1070.
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Harry Heaney & Jian Cui. 2001. Encyclopedia of Reagents for Organic Synthesis. Encyclopedia of Reagents for Organic Synthesis.
Mitsuo Sekine, Morihiro Aoyagi, Masatoshi Ushioda, Akihiro Ohkubo & Kohji Seio. (2005) Chemically Stabilized Phenylboranylidene Groups Having a Dimethoxytrityl Group as a Colorimetrically Detectable Protecting Group Designed for cis -1,2-Diol Functions of Ribonucleosides in the Solid-Phase Synthesis of m 2 2,2 G 5 ‘ ppT . The Journal of Organic Chemistry 70:21, pages 8400-8408.
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Akihiro Ohkubo, Katsufumi Aoki, Kohji Seio & Mitsuo Sekine. (2004) A new approach for pyrophosphate bond formation starting from phosphoramidite derivatives by use of 6-trifluoromethyl-1-hydroxybenzotriazole-mediated O–N phosphoryl migration. Tetrahedron Letters 45:5, pages 979-982.
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Michinori Kadokura, Takeshi Wada, Kohji Seio, Tomohisa Moriguchi, Jochen Huber, Reinhard Lührmann & Mitsuo Sekine. (2001) Solid-phase synthesis of a 5′-terminal TMG-capped trinucleotide block of U1 snRNA. Tetrahedron Letters 42:50, pages 8853-8856.
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Hiroyuki Tsuruoka, Koh-ichiroh Shohda, Takeshi Wada & Mitsuo Sekine. (2000) Synthesis and Conformational Properties of Oligonucleotides Incorporating 2‘- O -Phosphorylated Ribonucleotides as Structural Motifs of Pre-tRNA Splicing Intermediates . The Journal of Organic Chemistry 65:22, pages 7479-7494.
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Hiroyuki Tsuruoka, Koh-ichiroh Shohda, Takeshi Wada & Mitsuo Sekine. (1997) Kinetics and Mechanism of Facile and Selective Dephosphorylation of 2‘-Phosphorylated and 2‘-Thiophosphorylated Dinucleotides:  Neighboring 3‘−5‘ Phosphodiester Promotes 2‘-Dephosphorylation. The Journal of Organic Chemistry 62:9, pages 2813-2822.
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Hiroyuki Tsuruoka, Koh-ichiroh Shohda, Takeshi Wada & Mitsuo Sekine. (1996) Synthesis and structural and thermodynamic properties of oligonucleotides containing 2?-O-phosphorylated ribonucleosides. Tetrahedron Letters 37:37, pages 6741-6744.
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Mitsuo Sekine, Hiroyuki Tsuruoka, Shin Iimura, Hiroshi Kusuoku, Takeshi Wada & Kiyotaka Furusawa. (1996) Studies on Steric and Electronic Control of 2‘−3‘ Phosphoryl Migration in 2‘-Phosphorylated Uridine Derivatives and Its Application to the Synthesis of 2‘-Phosphorylated Oligouridylates. The Journal of Organic Chemistry 61:12, pages 4087-4100.
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