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Journal of Environmental Science and Health, Part C
Environmental Carcinogenesis and Ecotoxicology Reviews
Volume 28, 2010 - Issue 1
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Original Articles

Gene Expression Profiling as an Initial Approach for Mechanistic Studies of Toxicity and Tumorigenicity of Herbal Plants and Herbal Dietary Supplements

Lei Guo Division of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, FDA, AR, USA
,
Nan Mei Division of Genetic and Reproductive Toxicology, National Center for Toxicological Research, Jefferson, FDA, AR, USA
,
Qingsu Xia Division of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, FDA, AR, USA
,
Tao Chen Division of Genetic and Reproductive Toxicology, National Center for Toxicological Research, Jefferson, FDA, AR, USA
,
Po-Chuen Chan National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA
&
Peter P. Fu Division of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, FDA, AR, USA
Pages 60-87 | Published online: 18 Mar 2010

Citations (19)

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Read on this site (3)

Xiaoqing Guo & Nan Mei. (2016) Aloe vera: A review of toxicity and adverse clinical effects. Journal of Environmental Science and Health, Part C 34:2, pages 77-96.
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Si Chen, William B. Melchior$suffix/text()$suffix/text() & Lei Guo. (2014) Endoplasmic Reticulum Stress in Drug- and Environmental Toxicant-Induced Liver Toxicity. Journal of Environmental Science and Health, Part C 32:1, pages 83-104.
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CHIN-HSIAO TSENG & FARN-HSUAN TSENG. (2012) Peroxisome Proliferator-Activated Receptor Agonists and Bladder Cancer: Lessons from Animal Studies. Journal of Environmental Science and Health, Part C 30:4, pages 368-402.
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Articles from other publishers (16)

Noor Hadi Farhan, H.M. Abo Almaali & Marwah Ali Zghair. (2023) Complementary/combined treatment of depression in rats: Aloe Vera, fluoxetine, acupuncture. An experimental study. Revista Internacional de Acupuntura 17:4, pages 100267.
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Yan Wang, Chang Li, Zhongyv Xiong, Niangen Chen, Xuesong Wang, Junyv Xu, Yuemei Wang, Longfeng Liu, Hang Wu, Caihui Huang, Aiqin Huang, Jiajia Tan, Youbin Li & Qifu Li. (2022) Up-and-coming anti-epileptic effect of aloesone in Aloe vera: Evidenced by integrating network pharmacological analysis, in vitro, and in vivo models. Frontiers in Pharmacology 13.
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Nan Mei, Tao Chen, Baitang Ning & Lei Guo. 2021. Nutraceuticals. Nutraceuticals 299 313 .
Chukwuebuka Egbuna, Ena Gupta, Shahira M. Ezzat, Jaison Jeevanandam, Neha Mishra, Muhammad Akram, N. Sudharani, Charles Oluwaseun Adetunji, Priyanka Singh, Jonathan C. Ifemeje, S. Deepak, A. Bhavana, Angelo Mark P. Walag, Rumaisa Ansari, Juliana Bunmi Adetunji, Umme Laila, Michael Chinedu Olisah & Peculiar Feenna Onyekere. 2020. Functional Foods and Nutraceuticals. Functional Foods and Nutraceuticals 337 387 .
Nadire Özenver & Thomas Efferth. 2020. Approaching Complex Diseases. Approaching Complex Diseases 355 392 .
Alireza Tavakkoli, Mehrdad Iranshahi, S. Hossein Hasheminezhad, A. Wallace Hayes & Gholamreza Karimi. (2019) The neuroprotective activities of natural products through the Nrf2 upregulation. Phytotherapy Research 33:9, pages 2256-2273.
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Michael Habs, Karin Binder, Stefan Krauss, Karolina Müller, Brigitte Ernst, Luzia Valentini & Michael Koller. (2018) A Balanced Risk-Benefit Analysis to Determine Human Risks Associated with Pyrrolizidine Alkaloids (PA)—The Case of Herbal Medicinal Products Containing St. John’s Wort Extracts (SJW). Nutrients 10:7, pages 804.
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Si Chen, Qiangen Wu, Baitang Ning, Matthew Bryant & Lei Guo. (2018) The role of hepatic cytochrome P450s in the cytotoxicity of dronedarone. Archives of Toxicology 92:6, pages 1969-1981.
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Michael Habs, Karin Binder, Stefan Krauss, Karolina Müller, Brigitte Ernst, Luzia Valentini & Michael Koller. (2017) A Balanced Risk–Benefit Analysis to Determine Human Risks Associated with Pyrrolizidine Alkaloids (PA)—The Case of Tea and Herbal Infusions. Nutrients 9:7, pages 717.
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Qiangen Wu, Baitang Ning, Jiekun Xuan, Zhen Ren, Lei Guo & Matthew S. Bryant. (2016) The role of CYP 3A4 and 1A1 in amiodarone-induced hepatocellular toxicity. Toxicology Letters 253, pages 55-62.
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Nan Mei, Jiekun Xuan, Tao Chen, Baitang Ning & Lei Guo. 2016. Nutraceuticals. Nutraceuticals 249 262 .
Mei-Ling Hou, Li-Wen Chang, Chi-Hung Lin, Lie-Chwen Lin & Tung-Hu Tsai. (2014) Comparative pharmacokinetics of rhein in normal and loperamide-induced constipated rats and microarray analysis of drug-metabolizing genes. Journal of Ethnopharmacology 155:2, pages 1291-1299.
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Si Chen, Liqing Wan, Letha Couch, Haixia Lin, Yan Li, Vasily N. Dobrovolsky, Nan Mei & Lei Guo. (2013) Mechanism study of goldenseal-associated DNA damage. Toxicology Letters 221:1, pages 64-72.
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Mei Lan Tan, Heng Kean Tan, Chern Ein Oon, Masanori Kuroyanagi & Tengku Sifzizul Tengku Muhammad. (2012) Identification of genes involved in the regulation of 14-deoxy-11,12-didehydroandrographolide-induced toxicity in T-47D mammary cells. Food and Chemical Toxicology 50:2, pages 431-444.
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Yan Li, Hu Mei, Qiangen Wu, Suhui Zhang, Jia-Long Fang, Leming Shi & Lei Guo. (2011) Methysticin and 7,8-Dihydromethysticin are Two Major Kavalactones in Kava Extract to Induce CYP1A1. Toxicological Sciences 124:2, pages 388-399.
Crossref
Lei Guo, James C. Fuscoe, P. Fu & Nan Mei. 2009. General, Applied and Systems Toxicology. General, Applied and Systems Toxicology.

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