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Journal of Environmental Science and Health, Part C
Environmental Carcinogenesis and Ecotoxicology Reviews
Volume 28, 2010 - Issue 2
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Original Articles

The Role of MicroRNA in Chemical Carcinogenesis

Pages 89-124 | Published online: 14 Jun 2010

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Asmaa M. Elfiky, Asmaa Ahmed Mahmoud, Hala M. Zeidan & Mohamed Mostafa Soliman. (2019) Association between circulating microRNA-126 expression level and tumour necrosis factor alpha in healthy smokers. Biomarkers 24:5, pages 469-477.
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CHIN-HSIAO TSENG & FARN-HSUAN TSENG. (2012) Peroxisome Proliferator-Activated Receptor Agonists and Bladder Cancer: Lessons from Animal Studies. Journal of Environmental Science and Health, Part C 30:4, pages 368-402.
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William CS Cho. (2012) MicroRNAs as therapeutic targets and their potential applications in cancer therapy. Expert Opinion on Therapeutic Targets 16:8, pages 747-759.
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Articles from other publishers (50)

Khattapan Jantawongsri, Rasmus Dyrmose Nørregaard, Lis Bach, Rune Dietz, Christian Sonne, Kasper Jørgensen, Syverin Lierhagen, Tomasz Maciej Ciesielski, Bjørn Munro Jenssen, Courtney Alice Waugh, Ruth Eriksen, Barbara Nowak & Kelli Anderson. (2022) Effects of exposure to environmentally relevant concentrations of lead (Pb) on expression of stress and immune-related genes, and microRNAs in shorthorn sculpins (Myoxocephalus scorpius). Ecotoxicology 31:7, pages 1068-1077.
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Wei-Chiao Chiu, Da-Liang Ou & Ching-Ting Tan. (2022) Mouse Models for Immune Checkpoint Blockade Therapeutic Research in Oral Cancer. International Journal of Molecular Sciences 23:16, pages 9195.
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Khaled M. Elgeshy & Abdel Hady A. Abdel Wahab. (2022) The Role, Significance, and Association of MicroRNA-10a/b in Physiology of Cancer. MicroRNA 11:2, pages 118-138.
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Michal Sima, Andrea Rossnerova, Zuzana Simova & Pavel RossnerJr.Jr.. (2021) The Impact of Air Pollution Exposure on the MicroRNA Machinery and Lung Cancer Development. Journal of Personalized Medicine 11:1, pages 60.
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Nan Mei, Tao Chen, Baitang Ning & Lei Guo. 2021. Nutraceuticals. Nutraceuticals 299 313 .
Kameshwar P. Singh, Krishna P. Maremanda, Dongmei Li & Irfan Rahman. (2020) Exosomal microRNAs are novel circulating biomarkers in cigarette, waterpipe smokers, E-cigarette users and dual smokers. BMC Medical Genomics 13:1.
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Ana P. Ferragut Cardoso, Karen T. Udoh & J. Christopher States. (2020) Arsenic-induced changes in miRNA expression in cancer and other diseases. Toxicology and Applied Pharmacology 409, pages 115306.
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Tao Chen, Jian Yan & Zhiguang Li. (2020) Expression of miR-34a is a sensitive biomarker for exposure to genotoxic agents in human lymphoblastoid TK6 cells. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 856-857, pages 503232.
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Ran Jiang, Haoyu Huang, Zhenwei Lian, Zuqing Hu, R. Stephen Lloyd, Daokui Fang, Yanfeng Li, Hongyi Xian, Jianhui Yuan, Yan Sha, Sanming Wang & Dalin Hu. (2019) Exosomal miR‐221 derived from hydroquinone‐transformed malignant human bronchial epithelial cells is involved in cell viability of recipient cells. Journal of Applied Toxicology 40:2, pages 224-233.
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Andrew Walayat, Meizi Yang & DaLiao Xiao. 2019. Antisense Therapy. Antisense Therapy.
Amal Qattan. 2019. Genes and Cancer. Genes and Cancer.
Elham ChamaniJavad SargolzaeiTahmineh TavakoliZohreh Rezaei. (2019) microRNAs: Novel Markers in Diagnostics and Therapeutics of Celiac Disease. DNA and Cell Biology 38:7, pages 708-717.
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Tatiana S. Kalinina, Vladislav V. Kononchuk, Vladimir Y. Ovchinnikov, Mikhail D. Chanyshev & Lyudmila F. Gulyaeva. (2018) Expression of the miR-190 family is increased under DDT exposure in vivo and in vitro. Molecular Biology Reports 45:6, pages 1937-1945.
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Sanaa A. Rizk, Fateheya M. Metwally, Asmaa M. Elfiky, Asmaa A. Mahmoud, Nadia A. Badawi, Nevin E. Sharaf & Mahmoud M. Elhefnawi. (2018) Down-regulation of circulating microRNA let-7a in Egyptian smokers. Journal of Genetic Engineering and Biotechnology 16:1, pages 53-56.
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Gui‑Rong Hou, Kang Zeng, Hai‑Mei Lan & Qi Wang. (2018) Juglanin ameliorates UVB‑induced skin carcinogenesis via anti‑inflammatory and proapoptotic effects in vivo and in vitro. International Journal of Molecular Medicine.
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Zhi-Qiang Wang, Mei-Yin Zhang, Mei-Ling Deng, Nuo-Qing Weng, Hui-Yun Wang & Shao-Xiong Wu. (2017) Low serum level of miR-485-3p predicts poor survival in patients with glioblastoma. PLOS ONE 12:9, pages e0184969.
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Lorne J. Hofseth, Ainsley Weston & Curtis C. Harris. 2016. Holland‐Frei Cancer Medicine. Holland‐Frei Cancer Medicine 1 25 .
Lyudmila F. Gulyaeva & Nicolay E. Kushlinskiy. (2016) Regulatory mechanisms of microRNA expression. Journal of Translational Medicine 14:1.
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Rui Duan, Yun Lu, Lingyan Hou, Lina Du, Lequn Sun & Xingfan Tang. (2016) U-shaped microRNA expression pattern could be a new concept biomarker for environmental estrogen. Frontiers of Environmental Science & Engineering 10:6.
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Hannian Huang, Kai Zhang, Yongyong Zhou, Xianfeng Ding, Liang Yu, Guonian Zhu & Jiangfeng Guo. (2016) MicroRNA-155 targets cyb561d2 in zebrafish in response to fipronil exposure . Environmental Toxicology 31:7, pages 877-886.
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MONICA NEAGU, CONSTANTIN CARUNTU, CAROLINA CONSTANTIN, DANIEL BODA, SABINA ZURAC, DEMETRIOS A. SPANDIDOS & ARISTIDIS M. TSATSAKIS. (2016) Chemically induced skin carcinogenesis: Updates in experimental models (Review). Oncology Reports 35:5, pages 2516-2528.
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Zhiguang Li, Taichun Qin, Kejian Wang, Michael Hackenberg, Jian Yan, Yuan Gao, Li-Rong Yu, Leming Shi, Zhenqiang Su & Tao Chen. (2015) Integrated microRNA, mRNA, and protein expression profiling reveals microRNA regulatory networks in rat kidney treated with a carcinogenic dose of aristolochic acid. BMC Genomics 16:1.
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Caixia Liu, Haohui Yu, Yan Zhang, Daochuan Li, Xiumei Xing, Liping Chen, Xiaowen Zeng, Dandan Xu, Qiming Fan, Yongmei Xiao, Wen Chen & Qing Wang. (2015) Upregulation of miR-34a-5p antagonizes AFB1-induced genotoxicity in F344 rat liver. Toxicon 106, pages 46-56.
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Jiangning Zhao, Quanyi Lu, Junfeng Zhu, Jianguo Fu & Yun-xian Chen. (2014) Prognostic value of miR-96 in patients with acute myeloid leukemia. Diagnostic Pathology 9:1.
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Yang Luan, Xinming Qi, Liang Xu, Jin Ren & Tao Chen. (2014) Absence of mature microRNAs inactivates the response of gene expression to carcinogenesis induced by N -ethyl- N -nitrosourea in mouse liver . Journal of Applied Toxicology 34:12, pages 1409-1417.
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Paola Muti, Andrea Sacconi, Ahmed Hossain, Sara Donzelli, Noa Bossel Ben Moshe, Federica Ganci, Sabina Sieri, Vittorio Krogh, Franco Berrino, Francesca Biagioni, Sabrina Strano, Joseph Beyene, Yosef Yarden & Giovanni Blandino. (2014) Downregulation of microRNAs 145-3p and 145-5p Is a Long-term Predictor of Postmenopausal Breast Cancer Risk: The ORDET Prospective Study. Cancer Epidemiology, Biomarkers & Prevention 23:11, pages 2471-2481.
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Fanxue Meng, Zhiguang Li, Jian Yan, Mugimane Manjanatha, Sharon Shelton, Stephanie Yarborough & Tao Chen. (2014) Tissue-specific microRNA responses in rats treated with mutagenic and carcinogenic doses of aristolochic acid. Mutagenesis 29:5, pages 357-365.
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Qiaoyuan Yang, Shaozhu Zhang, Huanying Liu, Jianjun Wu, Enwu Xu, Baoying Peng & Yiguo Jiang. (2014) Oncogenic role of long noncoding RNA AF118081 in anti-benzo[a]pyrene-trans-7,8-dihydrodiol-9,10-epoxide-transformed 16HBE cells. Toxicology Letters 229:3, pages 430-439.
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Qiaoyuan Yang, Enwu Xu, Jiabin Dai, Jianjun Wu, Shaozhu Zhang, Baoying Peng & Yiguo Jiang. (2014) miR-21 regulates N-methyl-N-nitro-N′-nitrosoguanidine-induced gastric tumorigenesis by targeting FASLG and BTG2. Toxicology Letters 228:3, pages 147-156.
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Jie Li, Zengrui Wu, Feixiong Cheng, Weihua Li, Guixia Liu & Yun Tang. (2014) Computational prediction of microRNA networks incorporating environmental toxicity and disease etiology. Scientific Reports 4:1.
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J. Christopher States, Ming Ouyang & C. William Helm. (2014) Systems approach to identify environmental exposures contributing to organ-specific carcinogenesis. Cancer Epidemiology 38:3, pages 321-327.
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Joost P. M. Melis, Kasper W. J. Derks, Tessa E. Pronk, Paul Wackers, Mirjam M. Schaap, Edwin Zwart, Wilfred F. J. van IJcken, Martijs J. Jonker, Timo M. Breit, Joris Pothof, Harry van Steeg & Mirjam Luijten. (2014) In vivo murine hepatic microRNA and mRNA expression signatures predicting the (non-)genotoxic carcinogenic potential of chemicals. Archives of Toxicology 88:4, pages 1023-1034.
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Takuji Tanaka, Masahito Shimizu, Takahiro Kochi & Hisataka Moriwaki. (2013) Chemical-induced Carcinogenesis. Journal of Experimental & Clinical Medicine 5:6, pages 203-209.
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Dongsheng Yan & Geir Skogerbø. 2013. microRNAs in Toxicology and Medicine. microRNAs in Toxicology and Medicine 113 131 .
Fanxue Meng, Yang Luan, Jian Yan & Tao Chen. 2013. microRNAs in Toxicology and Medicine. microRNAs in Toxicology and Medicine 101 112 .
Rongrong Wei, Guo-Liang Huang, Mei-Yin Zhang, Bin-Kui Li, Hui-Zhong Zhang, Ming Shi, Xiao-Qian Chen, Long Huang, Qing-Ming Zhou, Wei-Hua Jia, X.F. Steven Zheng, Yun-Fei Yuan & Hui-Yun Wang. (2013) Clinical Significance and Prognostic Value of microRNA Expression Signatures in Hepatocellular Carcinoma. Clinical Cancer Research 19:17, pages 4780-4791.
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Xun Li, Jianjun Wu, Jingli Zheng, Yuanqi Li, Ti Yang, Gongcheng Hu, Jiabin Dai, Qiaoyuan Yang, Lijun Dai & Yiguo Jiang. (2013) Altered miRNA Expression Profiles and miR-1a Associated With Urethane-Induced Pulmonary Carcinogenesis. Toxicological Sciences 135:1, pages 63-71.
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Weidong Ji, Lei Yang, Jianhui Yuan, Linqing Yang, Mei Zhang, Defeng Qi, Xiaolu Duan, Aiguo Xuan, Wenjuan Zhang, Jiachun Lu, Zhixiong Zhuang & Guohua Zeng. (2013) MicroRNA-152 targets DNA methyltransferase 1 in NiS-transformed cells via a feedback mechanism. Carcinogenesis 34:2, pages 446-453.
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Anisha BanerjeeKarsta Luettich. (2012) MicroRNAs as potential biomarkers of smoking-related diseases. Biomarkers in Medicine 6:5, pages 671-684.
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André Schrattenholz, Vukić Šoškić, Rainer Schöpf, Slobodan Poznanović, Martina Klemm-Manns & Karlfried Groebe. (2012) Protein biomarkers for in vitro testing of toxicology. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 746:2, pages 113-123.
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Daochuan Li, Qing Wang, Caixia Liu, Huawei Duan, Xiaowen Zeng, Bo Zhang, Xiaodong Li, Jian Zhao, Shifu Tang, Zhifang Li, Xiumei Xing, Ping Yang, Liping Chen, Junling Zeng, Xiaonian Zhu, Shixin Zhang, Zhengbao Zhang, Lu Ma, Zhini He, Erman Wang, Yongmei Xiao, Yuxin Zheng & Wen Chen. (2012) Aberrant Expression of miR-638 Contributes to Benzo(a)pyrene-Induced Human Cell Transformation. Toxicological Sciences 125:2, pages 382-391.
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Tao Chen, Zhiguang Li, Jian Yan, Xi Yang & William Salminen. (2012) MicroRNA expression profiles distinguish the carcinogenic effects of riddelliine in rat liver. Mutagenesis 27:1, pages 59-66.
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Meena Mahmood, Dan Casciano, Yang Xu & Alexandru S. Biris. (2012) Engineered nanostructural materials for application in cancer biology and medicine. Journal of Applied Toxicology 32:1, pages 10-19.
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Xudong Wu & Yijiang Song. (2011) Preferential regulation of miRNA targets by environmental chemicals in the human genome. BMC Genomics 12:1.
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Meena Mahmood, Zhiguang Li, Daniel Casciano, Mariya V. Khodakovskaya, Tao Chen, Alokita Karmakar, Enkeleda Dervishi, Yang Xu, Thikra Mustafa, Fumiya Watanabe, Ashley Fejleh, Morgan Whitlow, Mustafa Al-Adami, Anindya Ghosh & Alexandru S. Biris. (2011) Nanostructural materials increase mineralization in bone cells and affect gene expression through miRNA regulation. Journal of Cellular and Molecular Medicine 15:11, pages 2297-2306.
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Yao Zhao, Huanying Liu, Yuanqi Li, Jianjun Wu, Anne R. Greenlee, Chengfeng Yang & Yiguo Jiang. (2011) The role of miR-506 in transformed 16HBE cells induced by anti-benzo[a]pyrene-trans-7,8-dihydrodiol-9,10-epoxide. Toxicology Letters 205:3, pages 320-326.
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David Chen, Zhiguang Li & Tao Chen. (2011) Increased expression of miR‐34a in mouse spleen one day after exposure to N ‐ethyl‐ N ‐nitrosourea . Journal of Applied Toxicology 31:5, pages 496-498.
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Zhiguang Li, James C. Fuscoe & Tao Chen. (2011) MicroRNAs and their predicted target messenger RNAs are deregulated by Exposure to a Carcinogenic Dose of Comfrey in Rat Liver. Environmental and Molecular Mutagenesis 52:6, pages 469-478.
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Zhishan Wang, Yong Zhao, Eric Smith, Gregory J. Goodall, Paul A. Drew, Thomas Brabletz & Chengfeng Yang. (2011) Reversal and Prevention of Arsenic-Induced Human Bronchial Epithelial Cell Malignant Transformation by microRNA-200b. Toxicological Sciences 121:1, pages 110-122.
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Zhiguang Li, William S Branham, Stacey L Dial, Yexun Wang, Lei Guo, Leming Shi & Tao Chen. (2010) Genomic analysis of microRNA time-course expression in liver of mice treated with genotoxic carcinogen N-ethyl-N-nitrosourea. BMC Genomics 11:1.
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