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Supramolecular Chemistry Volume 23, 2011 - Issue 9
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Original Articles

Effect of cucurbit[n]urils on tropicamide and potential application in ocular drug delivery

Na'il Saleh Department of Chemistry, College of Science, UAE University, P.O. Box 17551, Al-Ain, United Arab EmiratesCorrespondence[email protected]
,
Mohammed A. Meetani Department of Chemistry, College of Science, UAE University, P.O. Box 17551, Al-Ain, United Arab Emirates
,
Leena Al-Kaabi Department of Chemistry, College of Science, UAE University, P.O. Box 17551, Al-Ain, United Arab Emirates
,
Indrajit Ghosh School of Engineering and Science, Jacobs University Bremen, Campus Ring 1, D-28759, Bremen, Germany
&
Werner M. Nau School of Engineering and Science, Jacobs University Bremen, Campus Ring 1, D-28759, Bremen, GermanyCorrespondence[email protected]
Pages 650-656 | Received 25 Feb 2011, Accepted 02 May 2011, Published online: 04 Jul 2011

Citations (36)

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Nial J. Wheate & Christina Limantoro. (2016) Cucurbit[n]urils as excipients in pharmaceutical dosage forms. Supramolecular Chemistry 28:9-10, pages 849-856.
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Articles from other publishers (35)

Kazem Karami, Azar Ramezanpour, Atefeh Aliyar Samani, Zahra Amirghofran, Hori Ghaneialvar & Parvaneh Bayat. (2023) Smart perhydroxycucurbit [6] uril functionalized magnetic graphene oxide for release of Naringin as an antitumor agent. Advanced Powder Technology 34:12, pages 104267.
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Valya Nikolova, Stefan Dobrev, Nikoleta Kircheva, Victoria Yordanova, Todor Dudev & Silvia Angelova. (2023) Host-guest complexation of cucurbit[7]uril and cucurbit[8]uril with the antimuscarinic drugs tropicamide and atropine. Journal of Molecular Graphics and Modelling 119, pages 108380.
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Mohammed A. Meetani, Ahmad Alhalabi, Mohammed K. Al-Tabaji, Abdulla Al-Hemyari, Haythem A. Saadeh & Na’il Saleh. (2022) Cucurbituril—assisted sensitive fluorescence detection and quantitation of naproxen drug in wastewater samples: Guest-host characterization and HPLC investigation. Frontiers in Chemistry 10.
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Jaroslav Pejchal, Petr Jošt, Lubica Múčková, Rudolf Andrýs, Miroslav Lísa & Jana Zdarova Karasova. (2022) A systematic evaluation of the cucurbit[7]uril pharmacokinetics and toxicity after a single dose and short-term repeated administration in mice. Archives of Toxicology 96:5, pages 1411-1421.
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Tanoy Dutta, Shrobona Banerjee & Apurba Lal Koner. (2021) Regulating endoplasmic reticulum localization of a fluorescent NBD adamantane conjugate by Cucurbit [7]uril. Chemical Physics Impact 3, pages 100051.
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Falguni Chandra, Tanoy Dutta & Apurba L. Koner. (2020) Supramolecular Encapsulation of a Neurotransmitter Serotonin by Cucurbit[7]uril. Frontiers in Chemistry 8.
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Hang Yin, Ziyi Wang & Ruibing Wang. 2020. Handbook of Macrocyclic Supramolecular Assembly. Handbook of Macrocyclic Supramolecular Assembly 647 671 .
Hang Yin, Qian Cheng, Roselyne Rosas, Stéphane Viel, Valérie Monnier, Laurence Charles, Didier Siri, Didier Gigmes, Olivier Ouari, Ruibing Wang, Anthony Kermagoret & David Bardelang. (2019) A Cucurbit[8]uril 2:2 Complex with a Negative p K a Shift . Chemistry – A European Journal 25:54, pages 12552-12559.
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Debapratim Das, Khaleel I. Assaf & Werner M. Nau. (2019) Applications of Cucurbiturils in Medicinal Chemistry and Chemical Biology. Frontiers in Chemistry 7.
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Rajesh K. K. Sanku, Ozlem O. Karakus, Monica Ilies & Marc A. Ilies. 2019. Targeted Nanosystems for Therapeutic Applications: New Concepts, Dynamic Properties, Efficiency, and Toxicity. Targeted Nanosystems for Therapeutic Applications: New Concepts, Dynamic Properties, Efficiency, and Toxicity 187 221 .
Hang Yin, Ziyi Wang & Ruibing Wang. 2019. Handbook of Macrocyclic Supramolecular Assembly. Handbook of Macrocyclic Supramolecular Assembly 1 25 .
Xiangjun Zhang, Xiaoqiu Xu, Shengke Li, Lian-Hui Wang, Jianxiang Zhang & Ruibing Wang. (2018) A systematic evaluation of the biocompatibility of cucurbit[7]uril in mice. Scientific Reports 8:1.
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Riina Aav & Kamini Mishra. (2018) The Breaking of Symmetry Leads to Chirality in Cucurbituril-Type Hosts. Symmetry 10:4, pages 98.
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Donal H. Macartney. (2018) Cucurbit[n]uril Host-Guest Complexes of Acids, Photoacids, and Super Photoacids. Israel Journal of Chemistry 58:3-4, pages 230-243.
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Alexandra I. Lazar, Jana Rohacova & Werner M. Nau. (2017) Comparison of Complexation-Induced p K a Shifts in the Ground and Excited States of Dyes as Well as Different Macrocyclic Hosts and Their Manifestation in Host-Retarded Excited-Dye Deprotonation . The Journal of Physical Chemistry B 121:50, pages 11390-11398.
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Kit Ieng Kuok, Shengke Li, Ian W. Wyman & Ruibing Wang. (2017) Cucurbit[7]uril: an emerging candidate for pharmaceutical excipients. Annals of the New York Academy of Sciences 1398:1, pages 108-119.
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D.H. Macartney. 2017. Comprehensive Supramolecular Chemistry II. Comprehensive Supramolecular Chemistry II 479 494 .
Mahesh Pattabiraman, Murthy V.S.N. Maddipatla & V. Ramamurthy. (2016) pH-Induced cucurbit[7]uril hydrogels: Understanding microenvironment of the aggregates through excited state reactivity of dibenzyl ketones. Journal of Photochemistry and Photobiology A: Chemistry 324, pages 53-61.
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Na'il Saleh, Marieh B. Al-Handawi, Muna S. Bufaroosha, Khaleel I. Assaf & Werner M. Nau. (2016) Tuning protonation states of tripelennamine antihistamines by cucurbit[7]uril. Journal of Physical Organic Chemistry 29:2, pages 101-106.
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Gyan Hari Aryal, Cooper Hawkins Battle, Tod A. Grusenmeyer, Mengyuan Zhu & Janarthanan Jayawickramarajah. (2016) A naphthalimide derived fluorescent sensor for solid-phase screening of cucurbit[7]uril–guest interactions. Chemical Communications 52:11, pages 2307-2310.
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Lama D. Malhis, Khaled Bodoor, Khaleel I. Assaf, Nada A. Al-Sakhen & Musa I. El-Barghouthi. (2015) Molecular dynamics simulation of a cucurbituril based molecular switch triggered by pH changes. Computational and Theoretical Chemistry 1066, pages 104-112.
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M. Olivia Kim, Patrick G. Blachly, Joseph W. Kaus & J. Andrew McCammon. (2014) Protocols Utilizing Constant pH Molecular Dynamics to Compute pH-Dependent Binding Free Energies. The Journal of Physical Chemistry B 119:3, pages 861-872.
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Paweł M. Nowak, Michał Woźniakiewicz, Mariusz P. Mitoraj, Magdalena Garnysz & Paweł Kościelniak. (2015) Modulation of pK a by cyclodextrins; subtle structural changes induce spectacularly different behaviors . RSC Advances 5:95, pages 77545-77552.
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Paweł Mateusz Nowak, Michał Woźniakiewicz, Mariusz Paweł Mitoraj, Filip Sagan & Paweł Kościelniak. (2015) Enthalpy–entropy relations in the acid–base equilibrium of warfarin and 10-hydroxywarfarin; joint experimental and theoretical studies. RSC Advances 5:91, pages 74562-74569.
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Khaleel I. Assaf & Werner M. Nau. (2015) Cucurbiturils: from synthesis to high-affinity binding and catalysis. Chemical Society Reviews 44:2, pages 394-418.
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Na’il Saleh, Suad M. Ajeb, Arjun Sham & Synan F. AbuQamar. (2013) Enhancement of in vitro fungicidal activity of fuberidazole to Botrytis cinerea by cucurbiturils. Journal of Inclusion Phenomena and Macrocyclic Chemistry 79:3-4, pages 301-309.
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Changjun Zou, Tong Gu, Pufu Xiao, Tingting Ge, Meng Wang & Kai Wang. (2014) Experimental Study of Cucurbit[7]uril Derivatives Modified Acrylamide Polymer for Enhanced Oil Recovery. Industrial & Engineering Chemistry Research 53:18, pages 7570-7578.
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Marian Seif, Michael L. Impelido, Michael G. Apps & Nial J. Wheate. (2014) Topical Cream-Based Dosage Forms of the Macrocyclic Drug Delivery Vehicle Cucurbit[6]uril. PLoS ONE 9:1, pages e85361.
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Na’il Saleh, Marieh B. Al-Handawi, Leena Al-Kaabi, Liaquat Ali, S. Salman Ashraf, Thies Thiemann, Bassam al-Hindawi & Mohammed Meetani. (2014) Intermolecular interactions between cucurbit[7]uril and pilocarpine. International Journal of Pharmaceutics 460:1-2, pages 53-62.
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Na’il Saleh, Indrajit Ghosh & Werner M. Nau. 2013. Supramolecular Systems in Biomedical Fields. Supramolecular Systems in Biomedical Fields 164 212 .
Na’il Saleh, Abbas Khaleel, Hmoud Al-Dmour, Bassam al-Hindawi & Elena Yakushenko. (2012) Host–guest complexes of cucurbit[7]uril with albendazole in solid state. Journal of Thermal Analysis and Calorimetry 111:1, pages 385-392.
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Indrajit Ghosh & Werner M. Nau. (2012) The strategic use of supramolecular pKa shifts to enhance the bioavailability of drugs. Advanced Drug Delivery Reviews 64:9, pages 764-783.
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Hany F. Nour, Nadim Hourani & Nikolai Kuhnert. (2012) Synthesis of novel enantiomerically pure tetra-carbohydrazide cyclophane macrocycles. Organic & Biomolecular Chemistry 10:22, pages 4381.
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Eric Masson, Xiaoxi Ling, Roymon Joseph, Lawrence Kyeremeh-Mensah & Xiaoyong Lu. (2012) Cucurbituril chemistry: a tale of supramolecular success. RSC Adv. 2:4, pages 1213-1247.
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Na’il Saleh, Yaseen A. Al-Soud, Leena Al-Kaabi, Indrajit Ghosh & Werner M. Nau. (2011) A coumarin-based fluorescent PET sensor utilizing supramolecular pKa shifts. Tetrahedron Letters 52:41, pages 5249-5254.
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