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Research Article

Antimicrobial activity of clove oil and its potential in the treatment of vaginal candidiasis

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Pages 555-561 | Received 04 May 2005, Accepted 10 Oct 2005, Published online: 08 Oct 2008

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Read on this site (6)

Omar K.H. Bani Domi & Homa Darmani. (2023) Syzygium aromaticum extracts debilitate Candida albicans by radically inhibiting its morphological plasticity and biofilm formation. Journal of Herbs, Spices & Medicinal Plants 29:4, pages 392-404.
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Arif Khan, Mohd Azam, Khaled S Allemailem, Faris Alrumaihi, Ahmad Almatroudi, Fahad A Alhumaydhi, Hafiz Iqtidar Ahmad, Masih Uzzaman Khan & Masood Alam Khan. (2021) Coadministration of Ginger Extract and Fluconazole Shows a Synergistic Effect in the Treatment of Drug-Resistant Vulvovaginal Candidiasis. Infection and Drug Resistance 14, pages 1585-1599.
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Luciani Gaspar de Toledo, Matheus Aparecido dos Santos Ramos, Patrícia Bento da Silva, Camila Fernanda Rodero, Veridiana de Sá Gomes, Anderson Noronha da Silva, Fernando Rogério Pavan, Isabel Cristiane da Silva, Fernando Bombarda Oda, Danilo Luis Flumignan, André Gonzaga dos Santos, Marlus Chorilli, Margarete Teresa Gottardo de Almeida & Taís Maria Bauab. (2020) Improved in vitro and in vivo Anti-Candida albicans Activity of Cymbopogon nardus Essential Oil by Its Incorporation into a Microemulsion System. International Journal of Nanomedicine 15, pages 10481-10497.
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Alberto Angioni, Giorgia Sarais, Marinella Melis, Maria Teresa Russo, Mario Schirra & Salvatore D’Aquino. (2016) Postharvest applications of clove essential oils on dry seeds stored under simulated warehouse conditions. Journal of Essential Oil Research 28:1, pages 15-21.
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José das Neves, Eugénia Pinto, Maria Helena Amaral & Maria Fernanda Bahia. (2009) Antifungal activity of a gel containing Thymus vulgaris essential oil against Candida species commonly involved in vulvovaginal candidosis. Pharmaceutical Biology 47:2, pages 151-153.
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Bill D Misner. (2007) A novel aromatic oil compound inhibits microbial overgrowth on feet: a case study. Journal of the International Society of Sports Nutrition 4:1.
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Articles from other publishers (28)

Zahra Taghipour, Maryam Bahmanzadeh & Roja Rahimi. (2023) The Effects of Clove and Its Constituents on Reproductive System: a Comprehensive Review. Reproductive Sciences.
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Poonam Negi, Akriti Singh, Swati Pundir, Arun Parashar, Navneet Upadhyay, Shweta Agarwal, Raveen Chauhan & Murtaza M Tambuwala. (2023) Essential oil and nanocarrier-based formulations approaches for vaginal candidiasis. Therapeutic Delivery 14:3, pages 207-225.
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Amanda Martins Jordão, Isabela Trindade Coutinho, Eric Keven Silva, Ilka Tiemy Kato, Maria Angela A. Meireles, Lígia Passos Maia-Obi, Bruno Guzzo da Silva & Mathilde Champeau. (2022) Supercritical CO2 Impregnation of Clove Extract in Polycarbonate: Effects of Operational Conditions on the Loading and Composition. Processes 10:12, pages 2661.
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Amulya Jindal & Anoop Kumar. (2022) Physical characterization of clove oil based self Nano-emulsifying formulations of cefpodoxime proxetil: Assessment of dissolution rate, antioxidant & antibacterial activity. OpenNano 8, pages 100087.
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Abdulrab Ahmed M. Alkhanjaf, Md Tanwir Athar, Zabih Ullah, Ahmad Umar & Ibrahim Ahmed Shaikh. (2022) In Vitro and In Vivo Evaluation of a Nano-Tool Appended Oilmix (Clove and Tea Tree Oil) Thermosensitive Gel for Vaginal Candidiasis. Journal of Functional Biomaterials 13:4, pages 203.
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J. Ma, Y.-C. Yang, L.-Q. Su, D.-M. Qin, K. Yuan, Y. Zhang & R.-R. Wang. (2022) The liquid Kangfuxin (KFX) has efficient antifungal activity and can be used in the treatment of vulvovaginal candidiasis in mice. Letters in Applied Microbiology 74:4, pages 564-576.
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Saruchi, Anjali Saini & Vaneet Kumar. (2022) Antibacterial Activity of Indian Spices against the Pathogens Isolated from Wound Infection. Current Materials Science 15:1, pages 38-51.
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Miroslava Kačániová, Lucia Galovičová, Petra Borotová, Veronika Valková, Hana Ďúranová, Przemysław Łukasz Kowalczewski, Hussein A. H. Said-Al Ahl, Wafaa M. Hikal, Milena Vukic, Tatsiana Savitskaya, Dzmitrij Grinshpan & Nenad L. Vukovic. (2021) Chemical Composition, In Vitro and In Situ Antimicrobial and Antibiofilm Activities of Syzygium aromaticum (Clove) Essential Oil. Plants 10:10, pages 2185.
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Nazia Hassan, Salma Firdaus, Santwana Padhi, Asgar Ali & Zeenat Iqbal. (2021) Investigating natural antibiofilm components: a new therapeutic perspective against candidal vulvovaginitis. Medical Hypotheses 148, pages 110515.
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Ghada Abdel fatah, Aza Hassan, Rasha Saleh & Magdy Amer. (2020) The efficacy of clove and thyme against experimentally induced Candidiasis in broilers. Mansoura Veterinary Medical Journal 21:2, pages 25-31.
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Mahdi Jahani, Masoumeh Pira & Mohammad Hossein Aminifard. (2020) Antifungal effects of essential oils against Aspergillus niger in vitro and in vivo on pomegranate (Punica granatum) fruits. Scientia Horticulturae 264, pages 109188.
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Shivakalyani Adepu & Mudrika Khandelwal. (2020) Bacterial cellulose with microencapsulated antifungal essential oils: A novel double barrier release system. Materialia 9, pages 100585.
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Luciana Betzler de Oliveira de Siqueira, Ana Paula dos Santos Matos, Verônica da Silva Cardoso, Janaína Cecília Oliveira Villanova, Bruno da Costa Leal Ribeiro Guimarães, Elisabete Pereira dos Santos, Alane Beatriz Vermelho, Ralph Santos-Oliveira & Eduardo Ricci Junior. (2019) Clove oil nanoemulsion showed potent inhibitory effect against Candida spp. . Nanotechnology 30:42, pages 425101.
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Seyed Amin Khatibi, Ali Misaghi, Mir-Hassan Moosavy, Afshin Akhondzadeh Basti, Mohammad Kazem Koohi, Parivash Khosravi & Fatemeh Haghirosadat. (2017) Encapsulation of Zataria multiflora Bioss. Essential Oil into Nanoliposomes and in Vitro Antibacterial Activity Against Escherichia coli O157:H7 . Journal of Food Processing and Preservation 41:3, pages e12955.
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Prasopchai Tonglairoum, Tanasait Ngawhirunpat, Theerasak Rojanarata, Ruchadaporn Kaomongkolgit & Praneet Opanasopit. (2016) Fabrication and Evaluation of Nanostructured Herbal Oil/Hydroxypropyl-β-Cyclodextrin/Polyvinylpyrrolidone Mats for Denture Stomatitis Prevention and Treatment. AAPS PharmSciTech 17:6, pages 1441-1449.
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Jane Buckle. 2015. Clinical Aromatherapy. Clinical Aromatherapy 373 394 .
Keith Singletary. (2014) Clove. Nutrition Today 49:4, pages 207-224.
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Kyung-Yeob Lee, Da-Hae Kang & Hee-Taek Kim. (2013) The Effects of Syzygium aromaticum extract Spread on the Allergic Contact Dermatitis induced by DNCB. The Journal of Korean Oriental Medical Ophthalmology and Otolaryngology and Dermatology 26:4, pages 1-14.
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Yuxin Chen, Hong Zeng, Jun Tian, Xiaoquan Ban, Bingxin Ma & Youwei Wang. (2013) Antifungal mechanism of essential oil from Anethum graveolens seeds against Candida albicans. Journal of Medical Microbiology 62:8, pages 1175-1183.
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Bernd Nilius & Giovanni Appendino. 2013. Reviews of Physiology, Biochemistry and Pharmacology, Vol. 164. Reviews of Physiology, Biochemistry and Pharmacology, Vol. 164 1 76 .
Yu-Cui Li, Hai-Chun Liang, Hai-Ming Chen, Li-Rong Tan, Yu-Yang Yi, Zhen Qin, Wei-Min Zhang, Dian-Wei Wu, Chu-Wen Li, Rong-Feng Lin, Zi-Ren Su & Xiao-Ping Lai. (2012) Anti-Candida albicans activity and pharmacokinetics of pogostone isolated from Pogostemonis Herba. Phytomedicine 20:1, pages 77-83.
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Mohd Sajjad Ahmad Khan & Iqbal Ahmad. (2012) Biofilm inhibition by Cymbopogon citratus and Syzygium aromaticum essential oils in the strains of Candida albicans. Journal of Ethnopharmacology 140:2, pages 416-423.
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N. Nurdjannah & N. Bermawie. 2012. Handbook of Herbs and Spices. Handbook of Herbs and Spices 197 215 .
A. Garg & S. Singh. (2011) Enhancement in antifungal activity of eugenol in immunosuppressed rats through lipid nanocarriers. Colloids and Surfaces B: Biointerfaces 87:2, pages 280-288.
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Qamar Zia, Mohammad Farzuddin, Mairaj Ahmad Ansari, Maroof Alam, Azmat Ali, Iqbal Ahmad & Mohammad Owais. 2010. Combating Fungal Infections. Combating Fungal Infections 485 528 .
Eugénia Pinto, Luís Vale-Silva, Carlos Cavaleiro & Lígia Salgueiro. (2009) Antifungal activity of the clove essential oil from Syzygium aromaticum on Candida, Aspergillus and dermatophyte species. Journal of Medical Microbiology 58:11, pages 1454-1462.
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Abdel Moneim E. Sulieman .Iman M.O. El Boshra .El Amin A. El Khalifa .. (2007) Nutritive Value of Clove (Syzygium aromaticum) and Detection of Antimicrobial Effect of its Bud Oil. Research Journal of Microbiology 2:3, pages 266-271.
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Tieraona Low Dog. (2006) A Reason to Season: The Therapeutic Benefits of Spices and Culinary Herbs. EXPLORE 2:5, pages 446-449.
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