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Journal of Drug Targeting Volume 15, 2007 - Issue 9
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Research Article

A thermally responsive Tat-elastin-like polypeptide fusion protein induces membrane leakage, apoptosis, and cell death in human breast cancer cells

Iqbal Massodi Department of Biochemistry, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS39216, USA
&
Drazen Raucher Department of Biochemistry, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS39216, USA
Pages 611-622 | Received 26 Feb 2007, Accepted 06 Jun 2007, Published online: 08 Oct 2008

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Yanqing Bao, Lin Wang & Jianjun Sun. (2021) Post-translational knockdown and post-secretional modification of EsxA determine contribution of EsxA membrane permeabilizing activity for mycobacterial intracellular survival. Virulence 12:1, pages 312-328.
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Ana-Matea Mikecin, Leslie R. Walker, Marija Kuna & Drazen Raucher. (2014) Thermally targeted p21 peptide enhances bortezomib cytotoxicity in androgen-independent prostate cancer cell lines. Anti-Cancer Drugs 25:2, pages 189-199.
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Ying Liu, Zhilong Jia, Liwen Li & Fulin Chen. (2011) A genetically synthetic protein-based cationic polymer for siRNA delivery. Medical Hypotheses 76:2, pages 239-240.
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Wafa Hassouneh, Trine Christensen & Ashutosh Chilkoti. (2010) Elastin‐Like Polypeptides as a Purification Tag for Recombinant Proteins. Current Protocols in Protein Science 61:1.
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Iqbal Massodi, Shama Moktan, Aruna Rawat, Gene L. BidwellIIIIII & Drazen Raucher. (2010) Inhibition of ovarian cancer cell proliferation by a cell cycle inhibitory peptide fused to a thermally responsive polypeptide carrier. International Journal of Cancer 126:2, pages 533-544.
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Iqbal Massodi, Emily Thomas & Drazen Raucher. (2009) Application of Thermally Responsive Elastin-like Polypeptide Fused to a Lactoferrin-derived Peptide for Treatment of Pancreatic Cancer. Molecules 14:6, pages 1999-2015.
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Gene L. BidwellIIIIII, Aisha N. Davis & Drazen Raucher. (2009) Targeting a c-Myc inhibitory polypeptide to specific intracellular compartments using cell penetrating peptides. Journal of Controlled Release 135:1, pages 2-10.
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Iqbal Massodi, Gene L. BidwellIIIIII, Aisha Davis, Abby Tausend, Kimberly Credit, Michael Flessner & Drazen Raucher. (2009) Inhibition of ovarian cancer cell metastasis by a fusion polypeptide Tat-ELP. Clinical & Experimental Metastasis 26:3, pages 251-260.
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Eric Vivès, Julien Schmidt & André Pèlegrin. (2008) Cell-penetrating and cell-targeting peptides in drug delivery. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1786:2, pages 126-138.
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