Citations (70)
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Laura E. McCoubrey, Moe Elbadawi, Mine Orlu, Simon Gaisford & Abdul W. Basit. (2021) Harnessing machine learning for development of microbiome therapeutics. Gut Microbes 13:1.
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Marival Bermejo, Barbara Sanchez-Dengra, Marta Gonzalez-Alvarez & Isabel Gonzalez-Alvarez. (2020) Oral controlled release dosage forms: dissolution versus diffusion. Expert Opinion on Drug Delivery 17:6, pages 791-803.
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Faten Madani, Hassana Hsein, Virginie Busignies & Pierre Tchoreloff. (2020) An overview on dosage forms and formulation strategies for vaccines and antibodies oral delivery. Pharmaceutical Development and Technology 25:2, pages 133-148.
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Sheyda Ranjbar, Seyed Afshin Seyednejad, Haniye Azimi, Hossein Rezaeizadeh & Roja Rahimi. (2019) Emerging Roles of Probiotics in Prevention and Treatment of Breast Cancer: A Comprehensive Review of Their Therapeutic Potential. Nutrition and Cancer 71:1, pages 1-12.
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Min Soo Kim, Dong Woo Yeom, Sung Rae Kim, Ho Yub Yoon, Chang Hyun Kim, Ho Yong Son, Jin Han Kim, Sangkil Lee & Young Wook Choi. (2017) Development of a chitosan based double layer-coated tablet as a platform for colon-specific drug delivery. Drug Design, Development and Therapy 11, pages 45-57.
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Gopal Rai, Awesh K. Yadav, Narendra K. Jain & Govind P. Agrawal. (2015) Enteric-coated epichlorohydrin crosslinked dextran microspheres for site-specific delivery to colon. Drug Development and Industrial Pharmacy 41:12, pages 2018-2028.
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Alice L Smart, Simon Gaisford & Abdul W Basit. (2014) Oral peptide and protein delivery: intestinal obstacles and commercial prospects. Expert Opinion on Drug Delivery 11:8, pages 1323-1335.
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Yellela S. R. Krishnaiah & Mansoor A. Khan. (2012) Strategies of targeting oral drug delivery systems to the colon and their potential use for the treatment of colorectal cancer. Pharmaceutical Development and Technology 17:5, pages 521-540.
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Reinout C. A. Schellekens, Jan H. Baltink, Ellen M. Woesthuis, Frans Stellaard, Jos G. W. Kosterink, Herman J. Woerdenbag & Henderik W. Frijlink. (2012) Film coated tablets (ColoPulse technology) for targeted delivery in the lower intestinal tract: Influence of the core composition on release characteristics. Pharmaceutical Development and Technology 17:1, pages 40-47.
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Articles from other publishers (61)
Neha Datta, Charlotte Johnson, Dina Kao, Pratik Gurnani, Cameron Alexander, Christos Polytarchou & Tanya M. Monaghan. (2023) MicroRNA-based therapeutics for inflammatory disorders of the microbiota-gut-brain axis. Pharmacological Research 194, pages 106870.
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Crossref
K. V. M. KrishnaV. Jagannadha Patro. (2023) Articulation and Evaluation of Extended-Release Beads using a Sulfasalazine Drug. Asian Journal of Pharmacy and Technology, pages 25-28.
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May S. Thu, Thunnicha Ondee, Tanawin Nopsopon, Izzati A. K. Farzana, Joanne L. Fothergill, Nattiya Hirankarn, Barry J. Campbell & Krit Pongpirul. (2023) Effect of Probiotics in Breast Cancer: A Systematic Review and Meta-Analysis. Biology 12:2, pages 280.
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Laura E. McCoubrey, Alessia Favaron, Atheer Awad, Mine Orlu, Simon Gaisford & Abdul W. Basit. (2023) Colonic drug delivery: Formulating the next generation of colon-targeted therapeutics. Journal of Controlled Release 353, pages 1107-1126.
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Lingping Zhang, Marie Wahlgren & Björn Bergenståhl. (2022) Oil-Based Delivery Control Release System Targeted to the Later Part of the Gastrointestinal Tract—A Mechanistic Study. Pharmaceutics 14:5, pages 896.
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Crossref
Mirko Koziolek. 2022. Oral Drug Delivery for Modified Release Formulations. Oral Drug Delivery for Modified Release Formulations
25
38
.
Atheer Awad, Christine M. Madla, Laura E. McCoubrey, Fabiana Ferraro, Francesca K.H. Gavins, Asma Buanz, Simon Gaisford, Mine Orlu, Florence Siepmann, Juergen Siepmann & Abdul W. Basit. (2022) Clinical translation of advanced colonic drug delivery technologies. Advanced Drug Delivery Reviews 181, pages 114076.
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Christine M. Madla, Francesca K. H. Gavins, Sarah J. Trenfield & Abdul W. Basit. 2022. Biopharmaceutics. Biopharmaceutics
205
237
.
Francesca K. H. Gavins, Christine M. Madla, Sarah J. Trenfield, Laura E. McCoubrey, Abdul W. Basit & Mark McAllister. 2022. Biopharmaceutics. Biopharmaceutics
165
188
.
Saliha Moutaharrik, Alessandra Maroni, Alice Melocchi, Lucia Zema, Anastasia Foppoli, Matteo Cerea, Luca Palugan, Christel Neut, Florence Siepmann, Juergen Siepmann & Andrea Gazzaniga. (2021) Oral colon delivery platform based on a novel combination approach: Design concept and preliminary evaluation. Journal of Drug Delivery Science and Technology 66, pages 102919.
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Henusha D. Jhundoo, Tobias Siefen, Alfred Liang, Christoph Schmidt, John Lokhnauth, Brice Moulari, Arnaud Béduneau, Yann Pellequer, Crilles Casper Larsen & Alf Lamprecht. (2021) Anti-inflammatory effects of acacia and guar gum in 5-amino salicylic acid formulations in experimental colitis. International Journal of Pharmaceutics: X 3, pages 100080.
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Povilas Miknevicius, Ruta Zulpaite, Bettina Leber, Kestutis Strupas, Philipp Stiegler & Peter Schemmer. (2021) The Impact of Probiotics on Intestinal Mucositis during Chemotherapy for Colorectal Cancer: A Comprehensive Review of Animal Studies. International Journal of Molecular Sciences 22:17, pages 9347.
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Daniel Preisig, Felipe Varum, Roberto Bravo, Claudia Hartig, Johannes Spleiss, Sonia Abbes, Federico Caobelli, Damian Wild, Maxim Puchkov, Jörg Huwyler & Manuel Haschke. (2021) Colonic delivery of metronidazole-loaded capsules for local treatment of bacterial infections: A clinical pharmacoscintigraphy study. European Journal of Pharmaceutics and Biopharmaceutics 165, pages 22-30.
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Vipul Yadav, Yang Mai, Laura E. McCoubrey, Yasufumi Wada, Motoyasu Tomioka, Satofumi Kawata, Shrikant Charde & Abdul W. Basit. (2021) 5-Aminolevulinic Acid as a Novel Therapeutic for Inflammatory Bowel Disease. Biomedicines 9:5, pages 578.
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Alperen Abaci, Christina Gedeon, Anna Kuna & Murat Guvendiren. (2021) Additive Manufacturing of Oral Tablets: Technologies, Materials and Printed Tablets. Pharmaceutics 13:2, pages 156.
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Atheer Awad, Sarah J. Trenfield & Abdul W. Basit. 2021. Remington. Remington
333
358
.
Jung Min Kim, Da Hye Kim, Hyo Jeong Park, Hyun Woo Ma, I Seul Park, Mijeong Son, So Youn Ro, Seokmann Hong, Hyo Kyung Han, Soo Jeong Lim, Seung Won Kim & Jae Hee Cheon. (2020) Nanocomposites-based targeted oral drug delivery systems with infliximab in a murine colitis model. Journal of Nanobiotechnology 18:1.
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Manisha Pandey, Hira Choudhury, Joyce Lau Chui Fern, Alice Teo Kee Kee, Janice Kou, Jane Lee Jia Jing, How Chiu Her, Hong Sin Yong, Hon Chian Ming, Subrat Kumar Bhattamisra & Bapi Gorain. (2020) 3D printing for oral drug delivery: a new tool to customize drug delivery. Drug Delivery and Translational Research 10:4, pages 986-1001.
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Felipe Varum, Ana Cristina Freire, Hala M. Fadda, Roberto Bravo & Abdul W. Basit. (2020) A dual pH and microbiota-triggered coating (Phloral™) for fail-safe colonic drug release. International Journal of Pharmaceutics 583, pages 119379.
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Felipe Varum, Ana Cristina Freire, Roberto Bravo & Abdul W. Basit. (2020) OPTICORE™, an innovative and accurate colonic targeting technology. International Journal of Pharmaceutics 583, pages 119372.
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Juliane Fjelrad Christfort, Antonio José Guillot, Ana Melero, Lasse Højlund Eklund Thamdrup, Teresa M. Garrigues, Anja Boisen, Kinga Zór & Line Hagner Nielsen. (2020) Cubic Microcontainers Improve In Situ Colonic Mucoadhesion and Absorption of Amoxicillin in Rats. Pharmaceutics 12:4, pages 355.
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Liu Dou, Francesca K. H. Gavins, Yang Mai, Christine M. Madla, Farhan Taherali, Mine Orlu, Sudaxshina Murdan & Abdul W. Basit. (2020) Effect of Food and an Animal’s Sex on P-Glycoprotein Expression and Luminal Fluids in the Gastrointestinal Tract of Wistar Rats. Pharmaceutics 12:4, pages 296.
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Anastasia Foppoli, Alessandra Maroni, Saliha Moutaharrik, Alice Melocchi, Lucia Zema, Luca Palugan, Matteo Cerea & Andrea Gazzaniga. (2019) In vitro and human pharmacoscintigraphic evaluation of an oral 5-ASA delivery system for colonic release. International Journal of Pharmaceutics 572, pages 118723.
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Fiona McCartney, Mónica Rosa & David J. Brayden. (2019) Evaluation of Sucrose Laurate as an Intestinal Permeation Enhancer for Macromolecules: Ex Vivo and In Vivo Studies. Pharmaceutics 11:11, pages 565.
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Wooseong Kim, Soojin Kim, Sanghyun Ju, Hanju Lee, Seongkeun Jeong, Jin-Wook Yoo, In-Soo Yoon & Yunjin Jung. (2019) Colon-Targeted Delivery Facilitates the Therapeutic Switching of Sofalcone, a Gastroprotective Agent, to an Anticolitic Drug via Nrf2 Activation. Molecular Pharmaceutics 16:9, pages 4007-4016.
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Patrizio Scarozza, Heike Schmitt, Giovanni Monteleone, Markus F. Neurath & Raja Atreya. (2019) Oligonucleotides—A Novel Promising Therapeutic Option for IBD. Frontiers in Pharmacology 10.
Crossref
Crossref
Christina Pentafragka, Mira Symillides, Mark McAllister, Jennifer Dressman, Maria Vertzoni & Christos Reppas. (2019)
The impact of food intake on the luminal environment and performance of oral drug products with a view to
in vitro
and
in silico
simulations: a PEARRL review
. Journal of Pharmacy and Pharmacology 71:4, pages 557-580.
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Crossref
Mahira Zeeshan, Hussain Ali, Salman Khan, Saeed Ahmad Khan & Benno Weigmann. (2019) Advances in orally-delivered pH-sensitive nanocarrier systems; an optimistic approach for the treatment of inflammatory bowel disease. International Journal of Pharmaceutics 558, pages 201-214.
Crossref
Crossref
Dulan B. Gunasekara, Jennifer Speer, Yuli Wang, Daniel L. Nguyen, Mark I. Reed, Nicole M. Smiddy, Joel S. Parker, John K. Fallon, Philip C. Smith, Christopher E. Sims, Scott T. Magness & Nancy L. Allbritton. (2018) A Monolayer of Primary Colonic Epithelium Generated on a Scaffold with a Gradient of Stiffness for Drug Transport Studies. Analytical Chemistry 90:22, pages 13331-13340.
Crossref
Crossref
Grace B. Hatton, Christine M. Madla, Sarit C. Rabbie & Abdul W. Basit. (2018) All disease begins in the gut: Influence of gastrointestinal disorders and surgery on oral drug performance. International Journal of Pharmaceutics 548:1, pages 408-422.
Crossref
Crossref
J-M. Sauer & H.A. Merchant. 2018. Comprehensive Toxicology. Comprehensive Toxicology
16
44
.
Kantrol Kumar Sahu & Ravi Shankar Pandey. (2016) Immunological evaluation of colonic delivered Hepatitis B surface antigen loaded TLR-4 agonist modified solid fat nanoparticles. International Immunopharmacology 39, pages 343-352.
Crossref
Crossref
Jacoba M. Maurer, Susan Hofman, Reinout C.A. Schellekens, Wouter F. Tonnis, Annelien O.T. Dubois, Herman J. Woerdenbag, Wouter L.J. Hinrichs, Jos G.W. Kosterink & Henderik W. Frijlink. (2016) Development and potential application of an oral ColoPulse infliximab tablet with colon specific release: A feasibility study. International Journal of Pharmaceutics 505:1-2, pages 175-186.
Crossref
Crossref
Alvaro Goyanes, Hanah Chang, Daniel Sedough, Grace B. Hatton, Jie Wang, Asma Buanz, Simon Gaisford & Abdul W. Basit. (2015) Fabrication of controlled-release budesonide tablets via desktop (FDM) 3D printing. International Journal of Pharmaceutics 496:2, pages 414-420.
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Jie Wang, Vipul Yadav, Alice L. Smart, Shinichiro Tajiri & Abdul W. Basit. (2015) Stability of peptide drugs in the colon. European Journal of Pharmaceutical Sciences 78, pages 31-36.
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Crossref
Grace B. Hatton, Vipul Yadav, Abdul W. Basit & Hamid A. Merchant. (2015) Animal Farm: Considerations in Animal Gastrointestinal Physiology and Relevance to Drug Delivery in Humans. Journal of Pharmaceutical Sciences 104:9, pages 2747-2776.
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Jacoba M. Maurer, Reinout C. A. Schellekens, Hèlen M. van Rieke, Christoph Wanke, Ventzeslav Iordanov, Frans Stellaard, Klaus D. Wutzke, Gerard Dijkstra, Margot van der Zee, Herman J. Woerdenbag, Henderik W. Frijlink & Jos G. W. Kosterink. (2015) Gastrointestinal pH and Transit Time Profiling in Healthy Volunteers Using the IntelliCap System Confirms Ileo-Colonic Release of ColoPulse Tablets. PLOS ONE 10:7, pages e0129076.
Crossref
Crossref
Alvaro Goyanes, Grace B. Hatton, Hamid A. Merchant & Abdul W. Basit. (2015) Gastrointestinal release behaviour of modified-release drug products: Dynamic dissolution testing of mesalazine formulations. International Journal of Pharmaceutics 484:1-2, pages 103-108.
Crossref
Crossref
Alvaro Goyanes, Grace B. Hatton & Abdul W. Basit. (2015) A dynamic in vitro model to evaluate the intestinal release behaviour of modified-release corticosteroid products. Journal of Drug Delivery Science and Technology 25, pages 36-42.
Crossref
Crossref
Grzegorz Garbacz, Gerd-Martin Rappen, Mirko Koziolek & Werner Weitschies. (2015) Dissolution of mesalazine modified release tablets under standard and bio-relevant test conditions. Journal of Pharmacy and Pharmacology 67:2, pages 199-208.
Crossref
Crossref
Alvaro Goyanes, Asma B.M. Buanz, Grace B. Hatton, Simon Gaisford & Abdul W. Basit. (2015) 3D printing of modified-release aminosalicylate (4-ASA and 5-ASA) tablets. European Journal of Pharmaceutics and Biopharmaceutics 89, pages 157-162.
Crossref
Crossref
Amélia C.F. Vieira, Sudaxshina Murdan, Arménio C. Serra, Francisco J. Veiga, António M. d’A. Rocha Gonsalves & Abdul W. Basit. (2014) Influence of feeding regimens on rat gut fluids and colonic metabolism of diclofenac-β-cyclodextrin. Carbohydrate Polymers 112, pages 758-764.
Crossref
Crossref
Raj Kumar Shukla. (2013) Recent advances in oral anticancer agents for colon cancer. Future Oncology 9:12, pages 1893-1908.
Crossref
Crossref
J.M. Maurer, R.C.A. Schellekens, H.M. van Rieke, F. Stellaard, K.D. Wutzke, D.J. Buurman, G. Dijkstra, H.J. Woerdenbag, H.W. Frijlink & J.G.W. Kosterink. (2013) ColoPulse tablets perform comparably in healthy volunteers and Crohn's patients and show no influence of food and time of food intake on bioavailability. Journal of Controlled Release 172:3, pages 618-624.
Crossref
Crossref
F.J.O. Varum, G.B. Hatton & A.W. Basit. (2013) Food, physiology and drug delivery. International Journal of Pharmaceutics 457:2, pages 446-460.
Crossref
Crossref
F.J.O. Varum, G.B. Hatton, A.C. Freire & A.W. Basit. (2013) A novel coating concept for ileo-colonic drug targeting: Proof of concept in humans using scintigraphy. European Journal of Pharmaceutics and Biopharmaceutics 84:3, pages 573-577.
Crossref
Crossref
Amélia C.F. Vieira, Arménio C. Serra, Rui A. Carvalho, Alexandra Gonsalves, Ana Figueiras, Francisco J. Veiga, Abdul W. Basit & António M. d’A. Rocha Gonsalves. (2013) Microwave synthesis and in vitro stability of diclofenac-β-cyclodextrin conjugate for colon delivery. Carbohydrate Polymers 93:2, pages 512-517.
Crossref
Crossref
Mohamed Hassan G. Dehghan, V. Rama Mohan Gupta, Shaikh Mohammed Asif, Yusrida Darwis, Mohammad Rizwan & Veenu Piyush Mundada. (2012) Assessment of Isomalt for Colon-Specific Delivery and Its Comparison with Lactulose. AAPS PharmSciTech 14:1, pages 53-59.
Crossref
Crossref
Preethi Marimuthu & Andreas G. Schätzlein. 2013. Fundamentals of Pharmaceutical Nanoscience. Fundamentals of Pharmaceutical Nanoscience
301
336
.
Jing Liu, Liangke Zhang, Yuntao Jia, Wenjing Hu, Jingqing Zhang & Huiming Jiang. (2012) Preparation and evaluation of pectin-based colon-specific pulsatile capsule in vitro and in vivo. Archives of Pharmacal Research 35:11, pages 1927-1934.
Crossref
Crossref
Katie B. Ryan, Sam Maher, David J. Brayden & Caitriona M. O'driscoll*. 2012. Nanostructured Biomaterials for Overcoming Biological Barriers. Nanostructured Biomaterials for Overcoming Biological Barriers
63
90
.
Alessandra Maroni, Lucia Zema, Maria Dorly Del Curto, Anastasia Foppoli & Andrea Gazzaniga. (2012) Oral colon delivery of insulin with the aid of functional adjuvants. Advanced Drug Delivery Reviews 64:6, pages 540-556.
Crossref
Crossref
Raj Kumar Shukla & Akanksha Tiwari. (2012) Carbohydrate polymers: Applications and recent advances in delivering drugs to the colon. Carbohydrate Polymers 88:2, pages 399-416.
Crossref
Crossref
Ana C. Freire, Abdul W. Basit, Rahul Choudhary, Chee W. Piong & Hamid A. Merchant. (2011) Does sex matter? The influence of gender on gastrointestinal physiology and drug delivery. International Journal of Pharmaceutics 415:1-2, pages 15-28.
Crossref
Crossref
Ravi P. Sahu & Sanjay K. Srivastava. 2011. Functional Foods, Nutraceuticals, and Degenerative Disease Prevention. Functional Foods, Nutraceuticals, and Degenerative Disease Prevention
147
170
.
Viralkumar F. Patel, Fang Liu & Marc B. Brown. (2011) Advances in oral transmucosal drug delivery. Journal of Controlled Release 153:2, pages 106-116.
Crossref
Crossref
Mohamed A. Alhnan & Abdul W. Basit. (2011) Engineering polymer blend microparticles: An investigation into the influence of polymer blend distribution and interaction. European Journal of Pharmaceutical Sciences 42:1-2, pages 30-36.
Crossref
Crossref
Hamid A. Merchant, Emma L. McConnell, Fang Liu, Chandrasekaran Ramaswamy, Rucha P. Kulkarni, Abdul W. Basit & Sudaxshina Murdan. (2011) Assessment of gastrointestinal pH, fluid and lymphoid tissue in the guinea pig, rabbit and pig, and implications for their use in drug development. European Journal of Pharmaceutical Sciences 42:1-2, pages 3-10.
Crossref
Crossref
Abdul W. Basit & Emma L. McConnell. 2011. Controlled Release in Oral Drug Delivery. Controlled Release in Oral Drug Delivery
385
399
.
Jacques Huot & Nicole Beauchemin. 2010. Metastasis of Colorectal Cancer. Metastasis of Colorectal Cancer
409
411
.
Hala M. Fadda, Hamid A. Merchant, Basel T. Arafat & Abdul W. Basit. (2009) Physiological bicarbonate buffers: stabilisation and use as dissolution media for modified release systems. International Journal of Pharmaceutics 382:1-2, pages 56-60.
Crossref
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