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Journal of Drug Targeting Volume 27, 2019 - Issue 1
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Original Article

Overexpression of HOXC10 promotes glioblastoma cell progression to a poor prognosis via the PI3K/AKT signalling pathway

Yong GuanDepartment of Neurosurgery, Qingdao Minicipal Hospital, Qingdao, Shandong, PR China;
,
Yajie HeDepartment of Neurosurgery, Qingdao Minicipal Hospital, Qingdao, Shandong, PR China;
,
Shaoping LvDepartment of Rehabilitation, Qingdao Central Hospital, Qingdao, Shandong, PR China
,
Xiaoqun HouDepartment of Neurosurgery, Qingdao Minicipal Hospital, Qingdao, Shandong, PR China;
,
Luo LiDepartment of Neurosurgery, Qingdao Minicipal Hospital, Qingdao, Shandong, PR China;
&
Jianjun SongDepartment of Neurosurgery, Qingdao Minicipal Hospital, Qingdao, Shandong, PR China; Correspondence[email protected]
Pages 60-66 | Received 19 Jan 2018, Accepted 02 May 2018, Published online: 06 Aug 2018

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Kaiqin Wu, Zhenchuan Liu, Chenglai Dong, Shaorui Gu, Lei Li, Wenli Wang & Yongxin Zhou. (2022) MiR-4739 inhibits the malignant behavior of esophageal squamous cell carcinoma cells via the homeobox C10/vascular endothelial growth factor A/phosphatidylinositol 3-kinase/AKT pathway. Bioengineered 13:6, pages 14064-14077.
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Articles from other publishers (15)

Richard Morgan, Keith Hunter & Hardev S. Pandha. (2022) Downstream of the HOX genes: Explaining conflicting tumour suppressor and oncogenic functions in cancer . International Journal of Cancer 150:12, pages 1919-1932.
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Farzana Kabir & Mohd Nazmul Hasan Apu. (2022) Multi-omics analysis predicts fibronectin 1 as a prognostic biomarker in glioblastoma multiforme. Genomics 114:3, pages 110378.
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U Sangeetha Shenoy, Divya Adiga, Shama Prasada Kabekkodu, Keith D Hunter & Raghu Radhakrishnan. (2021) Molecular implications of HOX genes targeting multiple signaling pathways in cancer. Cell Biology and Toxicology 38:1, pages 1-30.
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Yuanxin Miao, Weina Zhang, Su Liu, Xiangfeng Leng, Chunnan Hu & Hao Sun. (2021) HOXC10 promotes growth and migration of melanoma by regulating Slug to activate the YAP/TAZ signaling pathway. Discover Oncology 12:1.
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Yangyang Feng, Tongyue Zhang, Yijun Wang, Meng Xie, Xiaoyu Ji, Xiangyuan Luo, Wenjie Huang & Limin Xia. (2021) Homeobox Genes in Cancers: From Carcinogenesis to Recent Therapeutic Intervention. Frontiers in Oncology 11.
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Ying Xie, Ran Chen, Liujia Yan, Zhangjun Jia, Guangshu Liang & Qin Wang. (2021) Transcription factor HOXC10 activates the expression of MTFR2 to regulate the proliferation, invasion and migration of colorectal cancer cells. Molecular Medicine Reports 24:5.
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Jinyong Fang, Jianjun Wang, Liangliang Yu & Wenxia Xu. (2021) Role of HOXC10 in Cancer. Frontiers in Oncology 11.
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Sonam Takkar, Vikas Sharma, Sourabh Ghosh, Ashish Suri, Chitra Sarkar & Ritu Kulshreshtha. (2021) Hypoxia-inducible miR-196a modulates glioblastoma cell proliferation and migration through complex regulation of NRAS. Cellular Oncology 44:2, pages 433-451.
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Céline S. Gonçalves, Elisa Le Boiteux, Philippe Arnaud & Bruno M. Costa. (2020) HOX gene cluster (de)regulation in brain: from neurodevelopment to malignant glial tumours. Cellular and Molecular Life Sciences 77:19, pages 3797-3821.
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Guohong Liu, Yunbao Pan, Yueying Li & Haibo Xu. (2020) lncRNA and mRNA signature for prognosis prediction of glioblastoma. Future Oncology 16:13, pages 837-848.
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Min Ma, Cuiru Wang, Yue Ao, Nimantana He, Fei Hao, Hao Liang & Dongjun Liu. (2020) HOXC10 promotes proliferation and attenuates lipid accumulation of sheep bone marrow mesenchymal stem cells. Molecular and Cellular Probes 49, pages 101491.
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Yuanbo Cui, Chunyan Zhang, Yaping Wang, Shanshan Ma, Wei Cao & Fangxia Guan. (2020) HOXC11 functions as a novel oncogene in human colon adenocarcinoma and kidney renal clear cell carcinoma. Life Sciences 243, pages 117230.
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Miao Yu, Jun Zhan & Hongquan Zhang. (2020) HOX family transcription factors: Related signaling pathways and post-translational modifications in cancer. Cellular Signalling 66, pages 109469.
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Sarah E. Bondos, Gabriela Geraldo Mendes & Amanda Jons. 2020. Dancing Protein Clouds: Intrinsically Disordered Proteins in Health and Disease, Part B. Dancing Protein Clouds: Intrinsically Disordered Proteins in Health and Disease, Part B 225 262 .
Weiyang Lou, Bisha Ding, Liang Xu & Weimin Fan. (2019) Construction of Potential Glioblastoma Multiforme-Related miRNA-mRNA Regulatory Network. Frontiers in Molecular Neuroscience 12.
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