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Journal of Drug Targeting Volume 30, 2022 - Issue 5
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Original Articles

Active-site molecular docking of nigellidine with nucleocapsid–NSP2–MPro of COVID-19 and to human IL1R–IL6R and strong antioxidant role of Nigella sativa in experimental rats

Smarajit Maitia Department of Biochemistry and Biotechnology, Cell and Molecular Therapeutics Laboratory Oriental Institute of Science and Technology, Midnapore, India;b Epidemiology and Human Health Division, Agricure Biotech Research Society, Midnapore, IndiaCorrespondence[email protected]
,
Amrita Banerjeea Department of Biochemistry and Biotechnology, Cell and Molecular Therapeutics Laboratory Oriental Institute of Science and Technology, Midnapore, India
,
Aarifa Nazmeena Department of Biochemistry and Biotechnology, Cell and Molecular Therapeutics Laboratory Oriental Institute of Science and Technology, Midnapore, India
,
Mehak Kanwara Department of Biochemistry and Biotechnology, Cell and Molecular Therapeutics Laboratory Oriental Institute of Science and Technology, Midnapore, India
&
Shilpa Dasa Department of Biochemistry and Biotechnology, Cell and Molecular Therapeutics Laboratory Oriental Institute of Science and Technology, Midnapore, India
Pages 511-521 | Received 11 May 2020, Accepted 25 Aug 2020, Published online: 18 Mar 2022

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Tao Yang, Si Chun Wang, Linyan Ye, Yasen Maimaitiyiming & Hua Naranmandura. (2023) Targeting viral proteins for restraining SARS-CoV-2: focusing lens on viral proteins beyond spike for discovering new drug targets. Expert Opinion on Drug Discovery 18:3, pages 247-268.
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Amrita Banerjee, Mehak Kanwar, Pradeep Kr. Das Mohapatra, Luciano Saso, Marcello Nicoletti & Smarajit Maiti. (2022) Nigellidine (Nigella sativa, black-cumin seed) docking to SARS CoV-2 nsp3 and host inflammatory proteins may inhibit viral replication/transcription and FAS-TNF death signal via TNFR 1/2 blocking. Natural Product Research 36:22, pages 5817-5822.
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Articles from other publishers (11)

Naina Mohamed Pakkir Maideen, Rajkapoor Balasubramanian, Mirunalini Gobinath, Mohamed Rafiullah & Sudha Muthusamy. (2023) Therapeutic Potentials of Black Seeds (Nigella sativa) in the Management of COVID-19 -A Review of Clinical and In-silico Studies. Anti-Infective Agents 21:1, pages 14-23.
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Sellappan Mohan, Jayagopal Dharani, Ramanathan Natarajan & Arumugam Nagarajan. (2022) Molecular docking and identification of G-protein-coupled receptor 120 (GPR120) agonists as SARS COVID-19 MPro inhibitors. Journal of Genetic Engineering and Biotechnology 20:1.
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Wei-Jung Chiu, Hong-Ren Chen, Indrajeet J. Barve & Chung-Ming Sun. (2022) Rh(III)-Catalyzed (4 + 1) Annulation of Pyrazol-3-ones with Alkynoates via Ortho -Alkenylation/Cyclization Cascade: Synthesis of Indazole-Fused Pyrazoles . The Journal of Organic Chemistry 87:18, pages 12109-12114.
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Arpita Roy & Tarunya Menon. (2021) Evaluation of bioactive compounds from Boswellia serrata against SARS-CoV-2. Vegetos 35:2, pages 404-414.
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Mohd Imran, Shah Alam Khan, Abida, Mohammed Kanan Alshammari, Saif M. Alkhaldi, Fayez Nafea Alshammari, Mehnaz Kamal, Ozair Alam, Syed Mohammed Basheeruddin Asdaq, A. Khuzaim Alzahrani & Shahamah Jomah. (2022) Nigella sativa L. and COVID-19: A Glance at The Anti-COVID-19 Chemical Constituents, Clinical Trials, Inventions, and Patent Literature. Molecules 27:9, pages 2750.
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Weizhu Yan, Yanhui Zheng, Xiaotao Zeng, Bin He & Wei Cheng. (2022) Structural biology of SARS-CoV-2: open the door for novel therapies. Signal Transduction and Targeted Therapy 7:1.
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Johra Khan, Ahmad Ali, Prairna Balyan & Eijaz A. Bhat. 2022. Black Seeds (Nigella Sativa). Black Seeds (Nigella Sativa) 337 354 .
Rajeev K. Singla, Xuefei He, Hitesh Chopra, Christos Tsagkaris, Li Shen, Mohammad Amjad Kamal & Bairong Shen. (2021) Natural Products for the Prevention and Control of the COVID-19 Pandemic: Sustainable Bioresources. Frontiers in Pharmacology 12.
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Noemí Cárdenas-Rodríguez, Cindy Bandala, América Vanoye-Carlo, Iván Ignacio-Mejía, Saúl Gómez-Manzo, Estefani Yaquelin Hernández-Cruz, José Pedraza-Chaverri, Liliana Carmona-Aparicio & Beatriz Hernández-Ochoa. (2021) Use of Antioxidants for the Neuro-Therapeutic Management of COVID-19. Antioxidants 10:6, pages 971.
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Sajad Fakhri, Sana Piri, Mohammad Bagher Majnooni, Mohammad Hosein Farzaei & Javier Echeverría. (2021) Targeting Neurological Manifestations of Coronaviruses by Candidate Phytochemicals: A Mechanistic Approach. Frontiers in Pharmacology 11.
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Dipannita Santra, Amrita Banerjee & Smarajit Maiti. 2021. Targeting Cellular Signalling Pathways in Lung Diseases. Targeting Cellular Signalling Pathways in Lung Diseases 583 599 .

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