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Journal of Drug Targeting Volume 29, 2021 - Issue 2
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Original Article

Development, optimisation and evaluation of chitosan nanoparticles of alendronate against Alzheimer’s disease in intracerebroventricular streptozotocin model for brain delivery

Saima Zameera Department of Pharmacology, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi, IndiaView further author information
,
Javed Alib Department of Pharmaceutics, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi, IndiaView further author information
,
Divya Vohoraa Department of Pharmacology, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi, IndiaView further author information
,
Abul Kalam Najmia Department of Pharmacology, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi, IndiaView further author information
&
Mohd Akhtara Department of Pharmacology, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi, IndiaCorrespondence[email protected]
View further author information
Pages 199-216 | Received 22 May 2020, Accepted 24 Aug 2020, Published online: 10 Sep 2020

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Debojyoti Halder, Subham Das & Alex Joseph. (2023) An insight into structure-activity relationship of naturally derived biological macromolecules for the treatment of Alzheimer’s disease: a review. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-17.
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Articles from other publishers (16)

Ana M. Matos, João Barros & Amélia P. Rauter. 2023. Carbohydrate‐Based Therapeutics. Carbohydrate‐Based Therapeutics 293 352 .
Mohammad Azam Ansari, Takshashila Tripathi, Baskar Venkidasamy, Alan Monziani, Govindasamy Rajakumar, Mohammad N. Alomary, Sami A. Alyahya, Oriane Onimus, Naomi D’souza, Md. Abul Barkat, Ebtesam A. Al-Suhaimi, Ramkumar Samynathan & Muthu Thiruvengadam. (2023) Multifunctional Nanocarriers for Alzheimer’s Disease: Befriending the Barriers. Molecular Neurobiology.
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Doaa Sayed Nady, Udo Bakowsky & Sherif Ashraf Fahmy. (2023) Recent advances in brain delivery of synthetic and natural nano therapeutics: Reviving hope for Alzheimer's disease patients. Journal of Drug Delivery Science and Technology 89, pages 105047.
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Manickam Rajkumar, Sundarraj Navaneethakrishnan, Sundarapandian Muthukumar, Ramasundaram Thangaraj, Magudeeswaran Sivanandam, Karuppaiya Vimala & Soundarapandian Kannan. (2023) Gelatin/polyethylene glycol-loaded magnesium hydroxide nanocomposite to attenuate acetylcholinesterase, neurotoxicity, and activation of GPR55 protein in rat models of Alzheimer's disease. Journal of Chemical Neuroanatomy 133, pages 102337.
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Fariba Mohebichamkhorami, Mehrdad Faizi, Matin Mahmoudifard, Arman Hajikarim‐Hamedani, Seyedeh Sarvenaz Mohseni, Amirhossein Heidari, Yekta Ghane, Mona Khoramjouy, Maryam Khayati, Rasoul Ghasemi, Hakimeh Zali, Simzar Hosseinzadeh & Ebrahim Mostafavi. (2023) Microfluidic Synthesis of Ultrasmall Chitosan/Graphene Quantum Dots Particles for Intranasal Delivery in Alzheimer's Disease Treatment. Small.
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Gayathri Rajamanickam & S. L. Manju. (2023) Formulation and characterization of chitosan nanoparticles loaded with neuroprotective flavonoid from Phyllanthus niruri Linn. Macromolecular Research 31:1, pages 13-24.
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Saeem Ahmad, Iram Khan, Jayamanti Pandit, Nasr A. Emad, Shahnaj Bano, Khalid Imtiyaz Dar, M. Moshahid Alam Rizvi, Mohd Danish Ansari, Mohd. Aqil & Yasmin Sultana. (2022) Brain targeted delivery of carmustine using chitosan coated nanoparticles via nasal route for glioblastoma treatment. International Journal of Biological Macromolecules 221, pages 435-445.
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Philippe Delbreil, Jean-Michel Rabanel, Xavier Banquy & Davide Brambilla. (2022) Therapeutic nanotechnologies for Alzheimer’s disease: A critical analysis of recent trends and findings. Advanced Drug Delivery Reviews 187, pages 114397.
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Yasmin M. Ahmed, Raha Orfali, Doaa S. Hamad, Mostafa E. Rateb & Hanan O. Farouk. (2022) Sustainable Release of Propranolol Hydrochloride Laden with Biconjugated-Ufasomes Chitosan Hydrogel Attenuates Cisplatin-Induced Sciatic Nerve Damage in In Vitro/In Vivo Evaluation. Pharmaceutics 14:8, pages 1536.
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Haidy Abbas, Nesrine S El Sayed, Nancy Abdel Hamid Abou Youssef, Passent M. E. Gaafar, Mohamed R. Mousa, Ahmed M. Fayez & Manal A Elsheikh. (2022) Novel Luteolin-Loaded Chitosan Decorated Nanoparticles for Brain-Targeting Delivery in a Sporadic Alzheimer’s Disease Mouse Model: Focus on Antioxidant, Anti-Inflammatory, and Amyloidogenic Pathways. Pharmaceutics 14:5, pages 1003.
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Ronghao Mu, Xian Wu, Danhua Yuan, Jiajia Zhao, Susu Tang, Hao Hong & Yan Long. (2022) Activation of TGR5 Ameliorates Streptozotocin-Induced Cognitive Impairment by Modulating Apoptosis, Neurogenesis, and Neuronal Firing. Oxidative Medicine and Cellular Longevity 2022, pages 1-23.
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Manal A. Elsheikh, Yasmin A. El-Feky, Majid Mohammad Al-Sawahli, Merhan E. Ali, Ahmed M. Fayez & Haidy Abbas. (2022) A Brain-Targeted Approach to Ameliorate Memory Disorders in a Sporadic Alzheimer’s Disease Mouse Model via Intranasal Luteolin-Loaded Nanobilosomes. Pharmaceutics 14:3, pages 576.
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Carely Hernandez & Surabhi Shukla. (2022) Liposome based drug delivery as a potential treatment option for Alzheimer’s disease. Neural Regeneration Research 17:6, pages 1190.
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Amit Kumar Nayak, Syed Anees Ahmad & Md Saquib Hasnain. 2022. Chitosan in Drug Delivery. Chitosan in Drug Delivery 55 82 .
Tahira Khan, Bushra Nabi, Saleha Rehman, Mohd. Akhtar, Javed Ali & Abul Kalam Najmi. (2021) Quality by Design Approach to Formulate Empagliflozin-Loaded Chitosan Nanoparticles: In Vitro , In Vivo and Pharmacokinetic Evaluation of Anti-Diabetic Drugs . Nano 16:13.
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