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SAR and QSAR in Environmental Research Volume 18, 2007 - Issue 1-2
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Original Articles

The role of the European Chemicals Bureau in promoting the regulatory use of (Q)SAR methodsFootnote†

A. P. Worth European Chemicals Bureau (ECB), Institute for Health and Consumer Protection, Joint Research Centre, European Commission, 21020 Ispra (VA), ItalyCorrespondence[email protected]
,
A. Bassan European Chemicals Bureau (ECB), Institute for Health and Consumer Protection, Joint Research Centre, European Commission, 21020 Ispra (VA), Italy
,
J. De Bruijn European Chemicals Bureau (ECB), Institute for Health and Consumer Protection, Joint Research Centre, European Commission, 21020 Ispra (VA), Italy
,
A. Gallegos Saliner European Chemicals Bureau (ECB), Institute for Health and Consumer Protection, Joint Research Centre, European Commission, 21020 Ispra (VA), Italy
,
T. Netzeva European Chemicals Bureau (ECB), Institute for Health and Consumer Protection, Joint Research Centre, European Commission, 21020 Ispra (VA), Italy
,
M. Pavan European Chemicals Bureau (ECB), Institute for Health and Consumer Protection, Joint Research Centre, European Commission, 21020 Ispra (VA), Italy
,
G. Patlewicz European Chemicals Bureau (ECB), Institute for Health and Consumer Protection, Joint Research Centre, European Commission, 21020 Ispra (VA), Italy
,
I. Tsakovska European Chemicals Bureau (ECB), Institute for Health and Consumer Protection, Joint Research Centre, European Commission, 21020 Ispra (VA), Italy
&
S. Eisenreich European Chemicals Bureau (ECB), Institute for Health and Consumer Protection, Joint Research Centre, European Commission, 21020 Ispra (VA), Italy
 show all
Pages 111-125 | Received 11 May 2006, Accepted 05 Aug 2006, Published online: 04 Dec 2010

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M. Asadollahi-Baboli. (2013) Straightforward MIA‐QSTR evaluation of environmental toxicities of aromatic aldehydes to Tetrahymena pyriformis. SAR and QSAR in Environmental Research 24:12, pages 1041-1050.
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Ramón García-Domenech, María Gálvez-Llompart, Riccardo Zanni, María C Recio & Jorge Gálvez. (2013) QSAR methods for the discovery of new inflammatory bowel disease drugs. Expert Opinion on Drug Discovery 8:8, pages 933-949.
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P. Ruiz, E. Myshkin, P. Quigley, O. Faroon, J.S. Wheeler, M.M. Mumtaz & R.J. Brennan. (2013) Assessment of hydroxylated metabolites of polychlorinated biphenyls as potential xenoestrogens: a QSAR comparative analysis∗ . SAR and QSAR in Environmental Research 24:5, pages 393-416.
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ROMUALDO BENIGNI. (2013) Evaluation of the Toxicity Forecasting Capability of EPA's ToxCast Phase I Data: Can ToxCast In Vitro Assays Predict Carcinogenicity?. Journal of Environmental Science and Health, Part C 31:3, pages 201-212.
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Romualdo Benigni. (2012) Alternatives to the carcinogenicity bioassay for toxicity prediction: are we there yet?. Expert Opinion on Drug Metabolism & Toxicology 8:4, pages 407-417.
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ROMUALDO BENIGNI, CECILIA BOSSA, ALESSANDRO GIULIANI & OLGA TCHEREMENSKAIA. (2010) Exploring In Vitro/In Vivo Correlation: Lessons Learned from Analyzing Phase I Results of the US EPA's ToxCast Project. Journal of Environmental Science and Health, Part C 28:4, pages 272-286.
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Romualdo Benigni, Cecilia Bossa, Olga Tcheremenskaia & Alessandro Giuliani. (2010) Alternatives to the carcinogenicity bioassay: in silico methods, and the in vitro and in vivo mutagenicity assays. Expert Opinion on Drug Metabolism & Toxicology 6:7, pages 809-819.
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E. Spencer Williams, Julie Panko & Dennis J. Paustenbach. (2009) The European Union’s REACH regulation: a review of its history and requirements. Critical Reviews in Toxicology 39:7, pages 553-575.
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M. Pavan & A.P. Worth. (2008) Publicly-accessible QSAR software tools developed by the Joint Research Centre† . SAR and QSAR in Environmental Research 19:7-8, pages 785-799.
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H. Niska, K. Tuppurainen, J.-P. Skön, A.K. Mallett & M. Kolehmainen. (2008) Characterisation of the chemical and biological properties of molecules with QSAR/QSPR and chemical grouping, and its application to a group of alkyl ethers. SAR and QSAR in Environmental Research 19:3-4, pages 263-284.
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G. Patlewicz, N. Jeliazkova, A. Gallegos Saliner & A.P. Worth. (2008) Toxmatch–a new software tool to aid in the development and evaluation of chemically similar groups. SAR and QSAR in Environmental Research 19:3-4, pages 397-412.
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Carol A. Marchant, Katharine A. Briggs & Anthony Long. (2008) In Silico Tools for Sharing Data and Knowledge on Toxicity and Metabolism: Derek for Windows, Meteor, and Vitic. Toxicology Mechanisms and Methods 18:2-3, pages 177-187.
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Uwe Lahl & Ursula Gundert-Remy. (2008) The Use of (Q)SAR Methods in the Context of REACH. Toxicology Mechanisms and Methods 18:2-3, pages 149-158.
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Romualdo Benigni & Cecilia Bossa. (2008) Predictivity and Reliability of QSAR Models: The Case of Mutagens and Carcinogens. Toxicology Mechanisms and Methods 18:2-3, pages 137-147.
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P. C. Von Der Ohe, R. Kühne, R. U. Ebert & G. Schüürmann. (2007) Comment on “Discriminating toxicant classes by mode of action: 3. Substructure indicators” (M. Nendza and M. Müller, SAR QSAR Environ. Res. 18 155 (2007)). SAR and QSAR in Environmental Research 18:7-8, pages 621-624.
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