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Original Articles

Influence of structural and functional modifications of selected genotoxic carcinogens on metabolism and mutagenicity – a review

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Pages 459-514 | Received 19 Oct 2006, Accepted 10 May 2007, Published online: 04 Dec 2010

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E. Fioravanzo, A. Bassan, M. Pavan, A. Mostrag-Szlichtyng & A.P. Worth. (2012) Role of in silico genotoxicity tools in the regulatory assessment of pharmaceutical impurities. SAR and QSAR in Environmental Research 23:3-4, pages 257-277.
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Sherif M. Eid, Khalid A.M. Attia, Ahmed El-Olemy, Ahmed Emad F. Abbas & Nahla A. Abdelshafi. (2023) An innovative nanoparticle-modified carbon paste sensor for ultrasensitive detection of lignocaine and its extremely carcinogenic metabolite residues in bovine food samples: Application of NEMI, ESA, AGREE, ComplexGAPI, and RGB12 algorithms. Food Chemistry 426, pages 136579.
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Mohammad Alizadeh, Meisam Barati, Sevda Saleh-Ghadimi, Neda Roshanravan, Reihaneh Zeinalian & Masoumeh Jabbari. (2018) Industrial furan and its biological effects on the body systems. Journal of Food Biochemistry 42:5, pages e12597.
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Gabriela L. Borosky. (2016) Mutagenicity of heteroaromatic amines: Computational study on the influence of methyl substituents. Journal of Molecular Graphics and Modelling 69, pages 92-102.
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Igor Shamovsky, Lena Ripa, Niklas Blomberg, Leif A. Eriksson, Peter Hansen, Christine Mee, Christian Tyrchan, Mike O'Donovan & Peter Sjö. (2012) Theoretical Studies of Chemical Reactivity of Metabolically Activated Forms of Aromatic Amines toward DNA. Chemical Research in Toxicology 25:10, pages 2236-2252.
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Igor Shamovsky, Lena Ripa, Lena Börjesson, Christine Mee, Bo Nordén, Peter Hansen, Catrin Hasselgren, Mike O’Donovan & Peter Sjö. (2011) Explanation for Main Features of Structure–Genotoxicity Relationships of Aromatic Amines by Theoretical Studies of Their Activation Pathways in CYP1A2. Journal of the American Chemical Society 133:40, pages 16168-16185.
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K. Periya Vijayalakshmi & Cherumuttathu H. Suresh. (2008) Theoretical studies on the carcinogenic activity of diol epoxide derivatives of PAH: proton affinity and aromaticity as decisive descriptors. Organic & Biomolecular Chemistry 6:23, pages 4384.
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