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SAR and QSAR in Environmental Research Volume 7, 1997 - Issue 1-4
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Original Articles

A Plausible Mechanism for the Mutagenic Activity (Salmonella typhimurium TA100) of MX Compounds: A Formation of CG-CG+-CG Radical Cation by One-electron Reduction

K. Tuppurainen Department of Chemistry, University of Kuopio, POB 1627, 70211, Kuopio, Finland
Pages 281-286 | Received 09 Jun 1997, Accepted 27 Jul 1997, Published online: 05 Oct 2006

Citations (11)

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Read on this site (2)

THOMASA. McDONALD & HANNU KOMULAINEN. (2005) Carcinogenicity of the Chlorination Disinfection By-Product MX. Journal of Environmental Science and Health, Part C 23:2, pages 163-214.
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David R. Geter, Richard N. Winn, John W. Fournie, Michelle B. Norris, Anthony B. DeAngelo & William E. Hawkins. (2004) MX [3-Chloro-4-(Dichloromethyl)-5-Hydroxy-2[5H]-Furanone], A Drinking-Water Carcinogen, Does Not Induce Mutations in the Liver of Cii Transgenic Medaka (Oryzias latipes). Journal of Toxicology and Environmental Health, Part A 67:5, pages 373-383.
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Articles from other publishers (9)

Elizabeth Rincon, Francisco Zuloaga & Eduardo Chamorro. (2013) Global and local chemical reactivities of mutagen X and simple derivatives. Journal of Molecular Modeling 19:6, pages 2573-2582.
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Rafael Gómez-Bombarelli, Emilio Calle & Julio Casado. (2012) DNA Damage by Genotoxic Hydroxyhalofuranones: An in Silico Approach to MX. Environmental Science & Technology 46:24, pages 13463-13470.
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William O. Ward, Carol D. Swartz, Nancy M. Hanley, John W. Whitaker, Robert Franzén & David M. DeMarini. (2009) Mutagen structure and transcriptional response: Induction of distinct transcriptional profiles in Salmonella TA100 by the drinking‐water mutagen MX and its homologues . Environmental and Molecular Mutagenesis 51:1, pages 69-79.
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Leon C. King, Susan D. Hester, Sarah H. Warren & David M. DeMarini. (2009) Induction of abasic sites by the drinking-water mutagen MX in Salmonella TA100. Chemico-Biological Interactions 180:3, pages 340-343.
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Andre Kimura Okamoto, Anderson Coser Gaudio, Alberto dos Santos Marques & Yuji Takahata. (2005) QSAR study of inibition by coumarins of IQ induced mutation in S. typhimurium TA98. Journal of Molecular Structure: THEOCHEM 725:1-3, pages 231-238.
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Jorma Mäki‐Paakkanen, Hannu Komulainen & Leif Kronberg. (2004) Bacterial and mammalian‐cell genotoxicity of mixtures of chlorohydroxyfuranones, by‐products of water chlorination. Environmental and Molecular Mutagenesis 43:4, pages 217-225.
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. (2003) Computational Study of Mutagen X. Bulletin of the Korean Chemical Society 24:6, pages 731-732.
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Jorma Mäki‐Paakkanen, Mariitta Laaksonen, Tony Munter, Leif Kronberg & Hannu Komulainen. (2001) Comparable DNA and chromosome damage in Chinese hamster ovary cells by chlorohydroxyfuranones. Environmental and Molecular Mutagenesis 38:4, pages 297-305.
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Kari Tuppurainen. (1999) Frontier orbital energies, hydrophobicity and steric factors as physical qsar descriptors of molecular mutagenicity. A review with a case study: MX compounds. Chemosphere 38:13, pages 3015-3030.
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