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Original Articles

Can mutagenicity information be useful in an Integrated Testing Strategy (ITS) for skin sensitization?

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Pages 619-656 | Received 14 May 2010, Accepted 08 Jul 2010, Published online: 29 Nov 2010

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Read on this site (2)

Christine Jäckh, Eric Fabian, Bennard van Ravenzwaay & Robert Landsiedel. (2012) Relevance of xenobiotic enzymes in human skin in vitro models to activate pro-sensitizers. Journal of Immunotoxicology 9:4, pages 426-438.
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O. Mekenyan, S. Dimitrov, T. Pavlov, G. Dimitrova, M. Todorov, P. Petkov & S. Kotov. (2012) Simulation of chemical metabolism for fate and hazard assessment. V. Mammalian hazard assessment. SAR and QSAR in Environmental Research 23:5-6, pages 553-606.
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Articles from other publishers (6)

Jueichuan (Connie) Kang & Luis G. ValerioJrJr. (2020) Investigating DNA adduct formation by flavor chemicals and tobacco byproducts in electronic nicotine delivery system (ENDS) using in silico approaches. Toxicology and Applied Pharmacology 398, pages 115026.
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Petko I Petkov, Terry W Schultz, Masamitsu Honma, Takashi Yamada, Elena Kaloyanova & Ovanes G Mekenyan. (2019) Validation of the performance of TIMES genotoxicity models with EFSA pesticide data. Mutagenesis 34:1, pages 83-90.
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Grace Patlewicz, Chanita Kuseva, Antonia Kesova, Ioanna Popova, Teodor Zhechev, Todor Pavlov, David W. Roberts & Ovanes Mekenyan. (2014) Towards AOP application – Implementation of an integrated approach to testing and assessment (IATA) into a pipeline tool for skin sensitization. Regulatory Toxicology and Pharmacology 69:3, pages 529-545.
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David W. Roberts & Grace Y. Patlewicz. (2014) Integrated testing and assessment approaches for skin sensitization: a commentary. Journal of Applied Toxicology 34:4, pages 436-440.
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Grace Patlewicz, Nicholas Ball, Ewan D. Booth, Etje Hulzebos, Elton Zvinavashe & Christa Hennes. (2013) Use of category approaches, read-across and (Q)SAR: General considerations. Regulatory Toxicology and Pharmacology 67:1, pages 1-12.
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Ovanes G. Mekenyan, Petko I. Petkov, Stefan V. Kotov, Stoyanka Stoeva, Verginia B. Kamenska, Sabcho D. Dimitrov, Masamitsu Honma, Makoto Hayashi, Romualdo Benigni, E. Maria Donner & Grace Patlewicz. (2012) Investigating the Relationship between in Vitro–in Vivo Genotoxicity: Derivation of Mechanistic QSAR Models for in Vivo Liver Genotoxicity and in Vivo Bone Marrow Micronucleus Formation Which Encompass Metabolism. Chemical Research in Toxicology 25:2, pages 277-296.
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