640
Views
23
CrossRef citations to date
0
Altmetric
Articles

Building on a solid foundation: SAR and QSAR as a fundamental strategy to reduce animal testingFootnote

, &
Pages 357-365 | Received 07 Feb 2014, Accepted 21 Feb 2014, Published online: 28 Apr 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

S. A. Kulkarni, E. Benfenati & T. S. Barton-Maclaren. (2016) Improving confidence in (Q)SAR predictions under Canada’s Chemicals Management Plan – a chemical space approach. SAR and QSAR in Environmental Research 27:10, pages 851-863.
Read now

Articles from other publishers (22)

Munmi Gogoi & Bijit Sensua. 2022. Encyclopedia of Green Materials. Encyclopedia of Green Materials 1 5 .
Sheikh Rezzak Ali, Shuby Kumari, Satyendra K. Prasad, Rupali S. Prasad, Saurabh K. Sinha & Anshul Shakya. 2023. Drug Discovery and Design Using Natural Products. Drug Discovery and Design Using Natural Products 3 21 .
Eva Hesping, Ming Jang Chua, Marc Pflieger, Yunan Qian, Lilong Dong, Prabhakar Bachu, Ligong Liu, Thomas Kurz, Gillian M. Fisher, Tina S. Skinner-Adams, Robert C. Reid, David P. Fairlie, Katherine T. Andrews & Alain-Dominique J.P. Gorse. (2022) QSAR Classification Models for Prediction of Hydroxamate Histone Deacetylase Inhibitor Activity against Malaria Parasites. ACS Infectious Diseases 8:1, pages 106-117.
Crossref
Asim Najmi, Sadique A. Javed, Mohammed Al Bratty & Hassan A. Alhazmi. (2022) Modern Approaches in the Discovery and Development of Plant-Based Natural Products and Their Analogues as Potential Therapeutic Agents. Molecules 27:2, pages 349.
Crossref
Jyoti Mehta, Rajan Rolta & Kamal Dev. (2022) Role of medicinal plants from North Western Himalayas as an efflux pump inhibitor against MDR AcrAB-TolC Salmonella enterica serovar typhimurium: In vitro and In silico studies. Journal of Ethnopharmacology 282, pages 114589.
Crossref
Kevin Dzobo. 2022. Comprehensive Pharmacology. Comprehensive Pharmacology 408 422 .
Shiv Bharadwaj, Amit Dubey, Nitin Kumar Kamboj, Amaresh Kumar Sahoo, Sang Gu Kang & Umesh Yadava. (2021) Drug repurposing for ligand-induced rearrangement of Sirt2 active site-based inhibitors via molecular modeling and quantum mechanics calculations. Scientific Reports 11:1.
Crossref
Marcus W. H. Wang, Jonathan M. Goodman & Timothy E. H. Allen. (2020) Machine Learning in Predictive Toxicology: Recent Applications and Future Directions for Classification Models. Chemical Research in Toxicology 34:2, pages 217-239.
Crossref
Gulcin Tugcu & Meric Koksal. (2018) A QSAR Study for Analgesic and Anti‐inflammatory Activities of 5‐/6‐Acyl‐3‐alkyl‐2‐Benzoxazolinone Derivatives. Molecular Informatics 38:8-9.
Crossref
Jae Hong Shin, Byeong Hun Lee & Sung Kwang Lee. (2019) Development of QSAR Model for Subchronic Inhalation Toxicity Using Random Forest Regression Method. Bulletin of the Korean Chemical Society 40:8, pages 819-825.
Crossref
Ignacio Ponzoni, Víctor Sebastián-Pérez, María J. Martínez, Carlos Roca, Carlos De la Cruz Pérez, Fiorella Cravero, Gustavo E. Vazquez, Juan A. Páez, Mónica F. Díaz & Nuria E. Campillo. (2019) QSAR Classification Models for Predicting the Activity of Inhibitors of Beta-Secretase (BACE1) Associated with Alzheimer’s Disease. Scientific Reports 9:1.
Crossref
Mark T.D. Cronin & Miyoung Yoon. 2019. The History of Alternative Test Methods in Toxicology. The History of Alternative Test Methods in Toxicology 287 300 .
Nicholas Thomford, Dimakatso Senthebane, Arielle Rowe, Daniella Munro, Palesa Seele, Alfred Maroyi & Kevin Dzobo. (2018) Natural Products for Drug Discovery in the 21st Century: Innovations for Novel Drug Discovery. International Journal of Molecular Sciences 19:6, pages 1578.
Crossref
Mabrouk Hamadache, Abdeltif Amrane, Salah Hanini & Othmane Benkortbi. (2018) Multilayer Perceptron Model for Predicting Acute Toxicity of Fungicides on Rats. International Journal of Quantitative Structure-Property Relationships 3:1, pages 100-118.
Crossref
Sana Ullah, Amina Zuberi, Mahmoud Alagawany, Mayada Ragab Farag, Maryam Dadar, Kumaragurubaran Karthik, Ruchi Tiwari, Kuldeep Dhama & Hafiz M.N. Iqbal. (2018) Cypermethrin induced toxicities in fish and adverse health outcomes: Its prevention and control measure adaptation. Journal of Environmental Management 206, pages 863-871.
Crossref
Cheryl A. Murphy, Roger M. Nisbet, Philipp Antczak, Natàlia Garcia-Reyero, Andre Gergs, Konstadia Lika, Teresa Mathews, Erik B. Muller, Diane Nacci, Angela Peace, Christopher H. Remien, Irvin R. Schultz & Karen H. Watanabe. 2018. A Systems Biology Approach to Advancing Adverse Outcome Pathways for Risk Assessment. A Systems Biology Approach to Advancing Adverse Outcome Pathways for Risk Assessment 281 302 .
Maryam Hamzeh-Mivehroud, Babak Sokouti & Siavoush Dastmalchi. 2017. Oncology. Oncology 20 66 .
Mabrouk Hamadache, Abdeltif Amrane, Othmane Benkortbi, Salah Hanini, Latifa Khaouane & Cherif Si Moussa. 2017. Advances in QSAR Modeling. Advances in QSAR Modeling 471 501 .
Mabrouk Hamadache, Othmane Benkortbi, Salah Hanini, Abdeltif Amrane, Latifa Khaouane & Cherif Si Moussa. (2016) A Quantitative Structure Activity Relationship for acute oral toxicity of pesticides on rats: Validation, domain of application and prediction. Journal of Hazardous Materials 303, pages 28-40.
Crossref
Ricard Garcia-Serna, David Vidal, Nikita Remez & Jordi Mestres. (2015) Large-Scale Predictive Drug Safety: From Structural Alerts to Biological Mechanisms. Chemical Research in Toxicology 28:10, pages 1875-1887.
Crossref
Hannu Raunio, Mira Kuusisto, Risto O. Juvonen & Olli T. Pentikäinen. (2015) Modeling of interactions between xenobiotics and cytochrome P450 (CYP) enzymes. Frontiers in Pharmacology 6.
Crossref
Maryam Hamzeh-Mivehroud, Babak Sokouti & Siavoush Dastmalchi. 2015. Quantitative Structure-Activity Relationships in Drug Design, Predictive Toxicology, and Risk Assessment. Quantitative Structure-Activity Relationships in Drug Design, Predictive Toxicology, and Risk Assessment 1 47 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.