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SAR and QSAR in Environmental Research Volume 32, 2021 - Issue 12
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Research Article

Discovery of Zafirlukast as a novel SARS-CoV-2 helicase inhibitor using in silico modelling and a FRET-based assay

N. Mehyara King Abdullah International Medical Research Center, Riyadh, Saudi Arabia;b King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia;c King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Riyadh, Saudi ArabiaView further author information
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A. Mashhoura King Abdullah International Medical Research Center, Riyadh, Saudi Arabia;b King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia;c King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Riyadh, Saudi ArabiaView further author information
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I. Islama King Abdullah International Medical Research Center, Riyadh, Saudi Arabia;b King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia;c King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Riyadh, Saudi ArabiaView further author information
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H.A. Alhadramid Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Rabigh, Saudi Arabia;e Molecular Diagnostic Laboratory, King Abdulaziz University Hospital, King Abdulaziz University, Jeddah, Saudi Arabia;f Special Infectious Agents Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi ArabiaView further author information
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A.M. Tolahd Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Rabigh, Saudi Arabia;f Special Infectious Agents Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi ArabiaView further author information
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B. Alghanema King Abdullah International Medical Research Center, Riyadh, Saudi Arabia;b King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia;c King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Riyadh, Saudi ArabiaView further author information
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S. Alkhaldia King Abdullah International Medical Research Center, Riyadh, Saudi Arabia;b King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia;c King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Riyadh, Saudi ArabiaView further author information
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B.A. Somaiea King Abdullah International Medical Research Center, Riyadh, Saudi Arabia;b King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia;c King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Riyadh, Saudi ArabiaView further author information
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M. Al Ghobaina King Abdullah International Medical Research Center, Riyadh, Saudi Arabia;b King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia;c King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Riyadh, Saudi ArabiaView further author information
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Y. Alobaidag Sudair Pharmaceutical Co, Riyadh, Saudi ArabiaView further author information
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A.S. Alaskara King Abdullah International Medical Research Center, Riyadh, Saudi Arabia;b King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia;c King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Riyadh, Saudi ArabiaView further author information
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M. Boudjelala King Abdullah International Medical Research Center, Riyadh, Saudi Arabia;b King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia;c King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Riyadh, Saudi ArabiaCorrespondence[email protected]
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Pages 963-983 | Received 12 Sep 2021, Accepted 12 Oct 2021, Published online: 25 Nov 2021

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