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Clinical and Experimental Hypertension Volume 42, 2020 - Issue 5
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Articles

Edaravone and benidipine protect myocardial damage by regulating mitochondrial stress, apoptosis signalling and cardiac biomarkers against doxorubicin-induced cardiotoxicity

Md Quamrul HassanDepartment of Pharmacology (Ilmul Advia), Ajmal Khan Tibbiya College, Aligarh Muslim University, Aligarh, India;Department of Pharmacology, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi, IndiaView further author information
,
Md Sayeed AkhtarDepartment of Pharmacology, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi, India;Department of Clinical Pharmacy, College of Pharmacy, King Khalid University, Abha, Kingdom of Saudi ArabiaView further author information
,
Obaid AfzalDepartment of Pharmaceutical chemistry, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi, IndiaView further author information
,
Ibraheem HussainDepartment of Pharmacology, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi, IndiaView further author information
,
Mohd AkhtarDepartment of Pharmacology, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi, IndiaView further author information
,
Syed Ehtaishamul HaqueDepartment of Pharmacology, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi, IndiaView further author information
&
Abul Kalam NajmiDepartment of Pharmacology, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi, IndiaCorrespondence[email protected]
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Pages 381-392 | Received 29 May 2019, Accepted 30 Sep 2019, Published online: 20 Oct 2019

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Emad H M Hassanein, Omnia A M Abd El-Ghafar, Marwa A Ahmed, Ahmed M Sayed, Wail M Gad-Elrab, Jamaan S Ajarem, Ahmed A Allam & Ayman M Mahmoud. (2020) Edaravone and Acetovanillone Upregulate Nrf2 and PI3K/Akt/mTOR Signaling and Prevent Cyclophosphamide Cardiotoxicity in Rats. Drug Design, Development and Therapy 14, pages 5275-5288.
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Articles from other publishers (17)

Xiao-bo Wang, Long-yun Zhou, Xu-qing Chen, Ran Li, Bin-bin Yu, Meng-xiao Pan, Lu Fang, Jian Li, Xue-jun Cui, Min Yao & Xiao Lu. (2023) Neuroprotective effect and possible mechanism of edaravone in rat models of spinal cord injury: a protocol for a systematic review and meta-analysis. Systematic Reviews 12:1.
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Kenan Yıldızhan, Zübeyir Huyut & Fikret Altındağ. (2022) Involvement of TRPM2 Channel on Doxorubicin-Induced Experimental Cardiotoxicity Model: Protective Role of Selenium. Biological Trace Element Research 201:5, pages 2458-2469.
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Kenan YILDIZHAN, Zübeyir HUYUT, Fikret ALTINDAĞ & Bünyamin UÇAR. (2023) EFFECT OF SELENIUM AND N-(P-AMYLCINNAMOYL) ANTHRANILIC ACID ON DOXORUBICIN-INDUCED KIDNEY INJURY IN RATSSıçanlarda Doksorubisin Kaynaklı Böbrek Hasarı Üzerine Selenyum ve N-(p-Amilsinnamoil) Antranilik Asit’in Etkisi. İnönü Üniversitesi Sağlık Hizmetleri Meslek Yüksek Okulu Dergisi 11:1, pages 1181-1191.
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Zehua Shao, Ran Li, Dongxing Shao, Hao Tang & Yu Han. (2022) Albumin-Based Zn (II)-Quercetin Enzyme Mimic Scavenging ROS for Protection against Cardiotoxicity Induced by Doxorubicin. Pharmaceuticals 15:12, pages 1524.
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Ye Chen, Saixian Shi & Yan Dai. (2022) Research progress of therapeutic drugs for doxorubicin-induced cardiomyopathy. Biomedicine & Pharmacotherapy 156, pages 113903.
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Yanxia Jiao, Chenlu Yuan, Tong Wu, Hongyan Zhang, Yuting Wei, Yuxia Ma, Xiujuan Zhang & Lin Han. (2022) Incidence of pressure injuries in fracture patients: A systematic review and meta-analysis. Journal of Tissue Viability 31:4, pages 726-734.
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Jaber Salehzadeh & Farough Nasiri. (2022) A facile one-pot synthesis of new functionalized pyrazolone-1,4-dithiafulvene hybrids. Molecular Diversity.
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V.M. Zhebel & O.L. Strazhynska. (2022) Нові можливості застосування блокатора ішемічного каскаду в терапії гострого інфаркту міокарда. EMERGENCY MEDICINE 18:1, pages 35-41.
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Toru Miyoshi, Kazufumi Nakamura, Naofumi Amioka, Omer F. Hatipoglu, Tomoko Yonezawa, Yukihiro Saito, Masashi Yoshida, Satoshi Akagi & Hiroshi Ito. (2022) LCZ696 ameliorates doxorubicin-induced cardiomyocyte toxicity in rats. Scientific Reports 12:1.
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Sun Joo Cha & Kiyoung Kim. (2022) Effects of the Edaravone, a Drug Approved for the Treatment of Amyotrophic Lateral Sclerosis, on Mitochondrial Function and Neuroprotection. Antioxidants 11:2, pages 195.
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Mohammad A.Y. Alqudah, Akram Al-Nosairy, Karem H. Alzoubi, Omar F. Kahbour & Sayer I. Alazzam. (2022) Edaravone prevents memory impairment in diabetic rats: Role of oxidative stress. Informatics in Medicine Unlocked 33, pages 101096.
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Mohammad Mehdi Ommati, Hanie Attari, Asma Siavashpour, Marzieh Shafaghat, Negar Azarpira, Hasti Ghaffari, Leila Moezi & Reza Heidari. (2021) Mitigation of cholestasis-associated hepatic and renal injury by edaravone treatment: Evaluation of its effects on oxidative stress and mitochondrial function. Liver Research 5:3, pages 181-193.
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Haidong Guo, Runfang Yang, Jin He, Ke Chen, Wen Yang, Junjun Liu, Kai Xiao & Hongxia Li. (2021) Edaravone combined with dexamethasone exhibits synergic effects on attenuating smoke-induced inhalation lung injury in rats. Biomedicine & Pharmacotherapy 141, pages 111894.
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Xing-Kai Qian, Jing Zhang, Pei-Fang Song, Yi-Su Zhao, Hong-Ying Ma, Qiang Jin, Dan-Dan Wang, Xiao-Qing Guan, Shi-Yang Li, XiaoZe Bao & Li-Wei Zou. (2021) Discovery of pyrazolones as novel carboxylesterase 2 inhibitors that potently inhibit the adipogenesis in cells. Bioorganic & Medicinal Chemistry 40, pages 116187.
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Mariapia Vairetti, Laura Giuseppina Di Pasqua, Marta Cagna, Plinio Richelmi, Andrea Ferrigno & Clarissa Berardo. (2021) Changes in Glutathione Content in Liver Diseases: An Update. Antioxidants 10:3, pages 364.
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Zhe Li, Arunachalam Chinnathambi, Sulaiman Ali Alharbi & Fuyu Yin. (2020) Plumbagin protects the myocardial damage by modulating the cardiac biomarkers, antioxidants, and apoptosis signaling in the doxorubicin‐induced cardiotoxicity in rats. Environmental Toxicology 35:12, pages 1374-1385.
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Haining Li, Bihua Xia, Wei Chen, Yumeng Zhang, Xia Gao, Arunachalam Chinnathambi, Sulaiman A. Alharbi & Yujie Zhao. (2020) Nimbolide prevents myocardial damage by regulating cardiac biomarkers, antioxidant level, and apoptosis signaling against doxorubicin‐induced cardiotoxicity in rats. Journal of Biochemical and Molecular Toxicology 34:9.
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