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Free Radical Research Volume 32, 2000 - Issue 1
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Original Article

Synaptosomal response to oxidative stress: Effect of vinpocetine

Maria S. Santos Department of Zoology and Faculty of Medicine, Center for Neurosciences of Coimbra, University of Coimbra, 3004-517, Coimbra, Portugal
,
Ana I. Duarte Department of Zoology and Faculty of Medicine, Center for Neurosciences of Coimbra, University of Coimbra, 3004-517, Coimbra, Portugal
,
Paula I. Moreira Department of Zoology and Faculty of Medicine, Center for Neurosciences of Coimbra, University of Coimbra, 3004-517, Coimbra, Portugal
&
Catarina R. Oliveira Department of Zoology and Faculty of Medicine, Center for Neurosciences of Coimbra, University of Coimbra, 3004-517, Coimbra, Portugal
Pages 57-66 | Received 16 Apr 1999, Published online: 07 Jul 2009

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. (2021) ALSUntangled 57: Vinpocetine. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 22:3-4, pages 316-319.
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Mamede de Carvalho. (2018) Cramps and vinpocetine in ALS. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 19:1-2, pages 155-156.
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Articles from other publishers (38)

Hayder M. Al-kuraishy, Athanasios Alexiou, Marios Papadakis, Omnya Elhussieny, Hebatallah M. Saad & Gaber El-Saber Batiha. (2023) New insights on the potential effect of vinpocetine in Parkinson’s disease: one of the neglected warden and baffling topics. Metabolic Brain Disease 38:6, pages 1831-1840.
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Meysam Shekarian, Iraj Salehi, Safoura Raoufi, Masoumeh Asadbegi, Masoumeh Kourosh-Arami & Alireza Komaki. (2023) Neuroprotective effects of vinpocetine, as a phosphodiesterase 1 inhibitor, on long-term potentiation in a rat model of Alzheimer’s disease. BMC Neuroscience 24:1.
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António M. Carvalho da Silva, Cristina Lemos, Henrique B. Silva, Ildete L. Ferreira, Angelo R. Tomé, A. Cristina Rego & Rodrigo A. Cunha. (2022) Simultaneous Alteration of the Circadian Variation of Memory, Hippocampal Synaptic Plasticity, and Metabolism in a Triple Transgenic Mouse Model of Alzheimer’s Disease. Frontiers in Aging Neuroscience 14.
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Shermineh Moini-Nodeh, Mahban Rahimifard, Maryam Baeeri, Mahshid Hodjat, Hamed Haghi-Aminjan & Mohammad Abdollahi. (2021) Vinpocetine Effect on the Juncture of Diabetes and Aging: An in-vitro study. Drug Research 71:08, pages 438-447.
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Hayder M. Al-kuraishy & Ali I. Al-Gareeb. 2021. Ischemic Stroke. Ischemic Stroke.
Surojit Paul & Eduardo Candelario-Jalil. (2021) Emerging neuroprotective strategies for the treatment of ischemic stroke: An overview of clinical and preclinical studies. Experimental Neurology 335, pages 113518.
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Meysam Shekarian, Alireza Komaki, Siamak Shahidi, Abdolrahman Sarihi, Iraj Salehi & Safoura Raoufi. (2020) The protective and therapeutic effects of vinpocetine, a PDE1 inhibitor, on oxidative stress and learning and memory impairment induced by an intracerebroventricular (ICV) injection of amyloid beta (aβ) peptide. Behavioural Brain Research 383, pages 112512.
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Jelena Ristic, Marko Folic, Katarina Radonjic, Milenko I. Rosic, Sergey Bolevich, Omarov Israpil Alisultanovich, Nevena Draginic, Marijana Andjic, Jovana Jeremic, Isidora Milosavljevic, Vladimir Zivkovic & Vladimir Jakovljevic. (2020) Preconditioning with PDE1 Inhibitors and Moderate-Intensity Training Positively Affect Systemic Redox State of Rats. Oxidative Medicine and Cellular Longevity 2020, pages 1-10.
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HayderM Al-Kuraishy, AliI Al-Gareeb, MarwaThaier Naji & Farah Al-Mamorry. (2020) Role of vinpocetine in ischemic stroke and poststroke outcomes: A critical review. Brain Circulation 6:1, pages 1.
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Yuri Lourenco-Gonzalez, Victor Fattori, Talita P. Domiciano, Ana C. Rossaneis, Sergio M. Borghi, Tiago H. Zaninelli, Catia C. F. Bernardy, Jose C. Alves-Filho, Thiago M. Cunha, Fernando Q. Cunha, Rubia Casagrande & Waldiceu A. Verri. (2019) Repurposing of the Nootropic Drug Vinpocetine as an Analgesic and Anti-Inflammatory Agent: Evidence in a Mouse Model of Superoxide Anion-Triggered Inflammation. Mediators of Inflammation 2019, pages 1-14.
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Bruna Mara Machado Ribeiro, Adriano José Maia Chaves Filho, Deiziane Viana da Silva Costa, Antônio Teles de Menezes, Anna Carolina Carvalho da Fonseca, Clarissa S. Gama, Vivaldo Moura Neto, David Freitas de Lucena, Mariana Lima Vale & Danielle S. Macêdo. (2019) N-3 polyunsaturated fatty acids and clozapine abrogates poly I: C-induced immune alterations in primary hippocampal neurons. Progress in Neuro-Psychopharmacology and Biological Psychiatry 90, pages 186-196.
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Bárbara B. Colombo, Victor Fattori, Carla F. S. Guazelli, Tiago H. Zaninelli, Thacyana T. Carvalho, Camila R. Ferraz, Allan J. C. Bussmann, Kenji W. Ruiz-Miyazawa, Marcela M. Baracat, Rúbia Casagrande & Waldiceu A. VerriJrJr. (2018) Vinpocetine Ameliorates Acetic Acid-Induced Colitis by Inhibiting NF-κB Activation in Mice. Inflammation 41:4, pages 1276-1289.
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Rania I. Nadeem, Hebatalla I. Ahmed & Bahia M. El-Sayeh. (2018) Protective effect of vinpocetine against neurotoxicity of manganese in adult male rats. Naunyn-Schmiedeberg's Archives of Pharmacology 391:7, pages 729-742.
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Lisa Nivison-Smith, Pauline Khoo, Monica L. Acosta & Michael Kalloniatis. (2018) Vinpocetine protects inner retinal neurons with functional NMDA glutamate receptors against retinal ischemia. Experimental Eye Research 167, pages 1-13.
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Yi-shuai Zhang, Jian-dong Li & Chen Yan. (2018) An update on vinpocetine: New discoveries and clinical implications. European Journal of Pharmacology 819, pages 30-34.
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Walaa Wadie & Dalia M. El-Tanbouly. (2017) Vinpocetine mitigates proteinuria and podocytes injury in a rat model of diabetic nephropathy. European Journal of Pharmacology 814, pages 187-195.
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Victor Fattori, Sergio M. Borghi, Carla F.S. Guazelli, Andressa C. Giroldo, Jefferson Crespigio, Allan J.C. Bussmann, Letícia Coelho-Silva, Natasha G. Ludwig, Tânia L. Mazzuco, Rubia Casagrande & Waldiceu A. VerriJr.Jr.. (2017) Vinpocetine reduces diclofenac-induced acute kidney injury through inhibition of oxidative stress, apoptosis, cytokine production, and NF-κB activation in mice. Pharmacological Research 120, pages 10-22.
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Lisa Nivison-Smith, Pauline Khoo, Monica L. Acosta & Michael Kalloniatis. (2017) Pre-treatment with vinpocetine protects against retinal ischemia. Experimental Eye Research 154, pages 126-138.
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Linjie Zhang & Li Yang. (2014) Anti-Inflammatory Effects of Vinpocetine in Atherosclerosis and Ischemic Stroke: A Review of the Literature. Molecules 20:1, pages 335-347.
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Wang Jincai, Dong Tingfang, Zhang Yongheng, Lu Zhongmin, Zhai Kaihua & Liu Xiaohong. (2014) Effects of vinpocetine and ozagrel on behavioral recovery of rats after global brain ischemia. Journal of Clinical Neuroscience 21:4, pages 661-663.
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Hala Fahmy ZakiRania Mohsen Abdelsalam. (2013) Vinpocetine protects liver against ischemia–reperfusion injury. Canadian Journal of Physiology and Pharmacology 91:12, pages 1064-1070.
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Nieves Herrera‐Mundo & María Sitges. (2012) Vinpocetine and α‐tocopherol prevent the increase in DA and oxidative stress induced by 3‐ NPA in striatum isolated nerve endings . Journal of Neurochemistry 124:2, pages 233-240.
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Yujun Cai, Walter E. Knight, Shujie Guo, Jian-Dong Li, Peter A. Knight & Chen Yan. (2012) Vinpocetine Suppresses Pathological Vascular Remodeling by Inhibiting Vascular Smooth Muscle Cell Proliferation and Migration. Journal of Pharmacology and Experimental Therapeutics 343:2, pages 479-488.
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Omar M. E. Abdel-Salam, Yasser A. Khadrawy, Neveen A. Salem & Amany A. Sleem. (2011) Oxidative Stress in a Model of Toxic Demyelination in Rat Brain: The Effect of Piracetam and Vinpocetine. Neurochemical Research 36:6, pages 1062-1072.
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P. Solanki, D. Prasad, S. Muthuraju, A.K. Sharma, S.B. Singh & G. Ilavzhagan. (2011) Preventive effect of Piracetam and Vinpocetine on hypoxia-reoxygenation induced injury in primary hippocampal culture. Food and Chemical Toxicology 49:4, pages 917-922.
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Con Stough, David Camfield, Christina Kure, Joanne Tarasuik, Luke Downey, Jenny Lloyd, Andrea Zangara, Andrew Scholey & Josh Reynolds. (2011) Improving general intelligence with a nutrient-based pharmacological intervention. Intelligence 39:2-3, pages 100-107.
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Hua-Ming SHENG, Zuo-Juan XIANG, Jun-Ting YE, Jin-Hong ZHENG & Hong-Bin SUN. (2011) Synthesis of Novel Alkylamino Substituted cis and trans Apovincamate Derivatives. Chinese Journal of Natural Medicines 9:1, pages 51-57.
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Abdel-Hasseb A. Fayed. (2009) Brain Trace Element Concentration of Rats Treated with the Plant Alkaloid, Vincamine. Biological Trace Element Research 136:3, pages 314-319.
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Rahul Deshmukh, Vivek Sharma, Sidharth Mehan, Nidhi Sharma & K.L. Bedi. (2009) Amelioration of intracerebroventricular streptozotocin induced cognitive dysfunction and oxidative stress by vinpocetine — a PDE1 inhibitor. European Journal of Pharmacology 620:1-3, pages 49-56.
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Jun Peng & Yuan-Jian Li. (2008) New insights into nitroglycerin effects and tolerance: Role of calcitonin gene-related peptide. European Journal of Pharmacology 586:1-3, pages 9-13.
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András Nemes, László Czibula, Csaba Szántay, Jr., Anikó Gere, Béla Kiss, Judit Laszy, István Gyertyán, Zsolt Szombathelyi & Csaba Szántay. (2008) Synthesis and Evaluation of 2′-Hydroxyethyl trans- Apovincaminate Derivatives as Antioxidant and Cognitive Enhancer Agents . Journal of Medicinal Chemistry 51:3, pages 479-486.
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Dániel Bereczki & István Fekete. (2008) Vinpocetine for acute ischaemic stroke. Cochrane Database of Systematic Reviews.
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Keith A. Wesnes, Andrea Zangara, Andrew Scholey & David Kennedy. 2004. Cognitive Enhancing Drugs. Cognitive Enhancing Drugs 151 178 .
Zoltán Nagy & László Simon. 2004. Frontiers in Clinical Neuroscience. Frontiers in Clinical Neuroscience 39 54 .
B. Gulyás, C. Halldin, J. Sandell, P. Karlsson, J. Sóvágó, E. Kárpáti, B. Kiss, Á. Vas, Z. Cselényi & L. Farde. (2002) PET studies on the brain uptake and regional distribution of [ 11 C]vinpocetine in human subjects . Acta Neurologica Scandinavica 106:6, pages 325-332.
Crossref
H. Hall, K. Varnäs, J. Sandell, C. Halldin, L. Farde, Á. Vas, E. Kárpáti & B. Gulyás. (2002) Autoradiographic evaluation of [ 11 C]vinpocetine binding in the human postmortem brain . Acta Biologica Hungarica 53:1-2, pages 59-66.
Crossref
Maria S. Santos, Dario L. Santos, Carlos M. Palmeira, Raquel Sei�a, Ant�nio J. Moreno & Catarina R. Oliveira. (2001) Brain and liver mitochondria isolated from diabeticGoto-Kakizaki rats show different susceptibility to induced oxidative stress. Diabetes/Metabolism Research and Reviews 17:3, pages 223-230.
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Péter Bönöczk, Balázs Gulyás, Vera Adam-Vizi, András Nemes, Egon Kárpáti, Béla Kiss, Margit Kapás, Csaba Szántay, István Koncz, Tibor Zelles & Adam Vas. (2000) Role of sodium channel inhibition in neuroprotection: effect of vinpocetine. Brain Research Bulletin 53:3, pages 245-254.
Crossref

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