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Original Article

Iron-induced oxidative DNA damage in rat sperm cells in vivo and in vitro

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Pages 75-83 | Received 22 Oct 1998, Published online: 07 Jul 2009

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A. Wellejus, M. Dalgaard & S. Loft. (2002) OXIDATIVE DNA DAMAGE IN MALE WISTAR RATS EXPOSED TO DI- n -BUTYL PHTHALATE. Journal of Toxicology and Environmental Health, Part A 65:11, pages 813-824.
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E. M. Samara, A. B. Okab, K. A. Abdoun, A. M. El-Waziry & A. A. Al-Haidary. (2013) Subsequent influences of feeding intact green seaweed Ulva lactuca to growing lambs on the seminal and testicular characteristics in rams1. Journal of Animal Science 91:12, pages 5654-5667.
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A. E. Calogero, S. La Vignera, R. A. Condorelli, A. Perdichizzi, D. Valenti, P. Asero, U. Carbone, B. Boggia, N. De Rosa, G. Lombardi, R. D’Agata, L. O. Vicari, E. Vicari & M. De Rosa. (2010) Environmental car exhaust pollution damages human sperm chromatin and DNA. Journal of Endocrinological Investigation 34:6, pages e139-e143.
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G. Delbes, B. F. Hales & B. Robaire. (2009) Toxicants and human sperm chromatin integrity. Molecular Human Reproduction 16:1, pages 14-22.
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Sabine A.S. Langie, Pawel Kowalczyk, Barbara Tudek, Romuald Zabielski, Tomasz Dziaman, Ryszard Oliński, Frederik J. van Schooten & Roger W.L. Godschalk. (2010) The effect of oxidative stress on nucleotide-excision repair in colon tissue of newborn piglets. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 695:1-2, pages 75-80.
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Alberto Velando, Roxana Torres & Carlos Alonso‐Alvarez. (2008) Avoiding bad genes: oxidatively damaged DNA in germ line and mate choice. BioEssays 30:11-12, pages 1212-1219.
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Terry T. Turner & Jeffrey J. Lysiak. (2013) Oxidative Stress: A Common Factor in Testicular Dysfunction. Journal of Andrology 29:5, pages 488-498.
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Eunju Park, Michael Glei, Yvonne Knöbel & Beatrice L. Pool-Zobel. (2007) Blood mononucleocytes are sensitive to the DNA damaging effects of iron overload—In vitro and ex vivo results with human and rat cells. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 619:1-2, pages 59-67.
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Zhongxiang Li, Jun Yang & Hefeng Huang. (2006) Oxidative stress induces H2AX phosphorylation in human spermatozoa. FEBS Letters 580:26, pages 6161-6168.
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Liga E. Bennetts & R. John Aitken. (2005) A comparative study of oxidative DNA damage in mammalian spermatozoa. Molecular Reproduction and Development 71:1, pages 77-87.
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Anja Wellejus, Jette Bornholdt, Ulla B. Vogel, Lotte Risom, Richard Wiger & Steffen Loft. (2004) Cell-specific oxidative DNA damage induced by estrogen in rat testicular cells in vitro. Toxicology Letters 150:3, pages 317-323.
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Dennis E. Sawyer, Belinda G. Mercer, Agnieszka M. Wiklendt & R.John Aitken. (2003) Quantitative analysis of gene-specific DNA damage in human spermatozoa. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 529:1-2, pages 21-34.
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Maria De Lourdes Pereira & Fernando Garciae Costa. (2016) Spermatogenesis recovery in the mouse after iron injury. Human & Experimental Toxicology 22:5, pages 275-279.
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D. Perera, A. Pizzey, A. Campbell, M. Katz, J. Porter, M. Petrou, D.S. Irvine & R. Chatterjee. (2002) Sperm DNA damage in potentially fertile homozygous  -thalassaemia patients with iron overload. Human Reproduction 17:7, pages 1820-1825.
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Aqel Abu-Qare & Mohamed Abou-Donia. (2000) Increased 8-hydroxy-2′-deoxyguanosine, a biomarker of oxidative DNA damage in rat urine following a single dermal dose of DEET (N,N-diethyl-m-toluamide), and permethrin, alone and in combination. Toxicology Letters 117:3, pages 151-160.
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