51
Views
60
CrossRef citations to date
0
Altmetric
Original Article

Caspase activation and cytochrome c release during HL-60 cell apoptosis induced by a nitric oxide donor

, , , &
Pages 507-514 | Received 09 Aug 1999, Published online: 07 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Zhuo Tang, Joseph A. Bauer, Bei Morrison & Daniel J. Lindner. (2006) Nitrosylcobalamin Promotes Cell Death via S Nitrosylation of Apo2L/TRAIL Receptor DR4. Molecular and Cellular Biology 26:15, pages 5588-5594.
Read now

Articles from other publishers (57)

Nitin Srivastava & Anil Kumar Saxena. (2023) Caspase-3 Activators as Anticancer Agents. Current Protein & Peptide Science 24:10, pages 783-804.
Crossref
Mehmet Gunata & Hakan Parlakpinar. (2020) A review of myocardial ischaemia/reperfusion injury: Pathophysiology, experimental models, biomarkers, genetics and pharmacological treatment. Cell Biochemistry and Function 39:2, pages 190-217.
Crossref
Juan José Poderoso, Katia Helfenberger & Cecilia Poderoso. (2019) The effect of nitric oxide on mitochondrial respiration. Nitric Oxide 88, pages 61-72.
Crossref
Guan-Ling Chou, Shu-Fen Peng, Ching-Lung Liao, Heng-Chien Ho, Kung-Wen Lu, Jin-Cherng Lien, Ming-Jen Fan, Kuang-Chi La & Jing-Gung Chung. (2018) Casticin impairs cell growth and induces cell apoptosis via cell cycle arrest in human oral cancer SCC-4 cells. Environmental Toxicology 33:2, pages 127-141.
Crossref
Vishal Kumar Vishwakarma, Prabhat Kumar Upadhyay, Jeetendra Kumar Gupta & Harlokesh Narayan Yadav. (2017) Pathophysiologic role of ischemia reperfusion injury: A review. Journal of Indian College of Cardiology 7:3, pages 97-104.
Crossref
Hung-Sheng Shang, Jia-You Liu, Hsu-Feng Lu, Han-Sun Chiang, Chia-Hain Lin, Ann Chen, Yuh-Feng Lin & Jing-Gung Chung. (2017) Casticin induced apoptotic cell death and altered associated gene expression in human colon cancer colo 205 cells. Environmental Toxicology 32:8, pages 2041-2052.
Crossref
Yu-Chieh Hsu, Jo-Hua Chiang, Chun-Shu Yu, Te-Chun Hsia, Rick Sai-Chuen Wu, Jin-Cherng Lien, Kuang-Chi Lai, Fu-Shun Yu & Jing-Gung Chung. (2017) Antitumor effects of deguelin on H460 human lung cancer cells in vitro and in vivo : Roles of apoptotic cell death and H460 tumor xenografts model . Environmental Toxicology 32:1, pages 84-98.
Crossref
Yin-Wen Shiue, Chi-Cheng Lu, Yu-Ping Hsiao, Ching-Lung Liao, Jing-Pin Lin, Kuang-Chi Lai, Chien-Chih Yu, Yi-Ping Huang, Heng-Chien Ho & Jing-Gung Chung. (2016) Casticin Induced Apoptosis in A375.S2 Human Melanoma Cells through the Inhibition of NF-κB and Mitochondria-Dependent Pathways In Vitro and Inhibited Human Melanoma Xenografts in a Mouse Model In Vivo . The American Journal of Chinese Medicine 44:03, pages 637-661.
Crossref
Hideo Fukuhara, Keiji Inoue, Atsushi Kurabayashi, Mutsuo Furihata, Hirofumi Fujita, Kozo Utsumi, Junzo Sasaki & Taro Shuin. (2013) The inhibition of ferrochelatase enhances 5-aminolevulinic acid-based photodynamic action for prostate cancer. Photodiagnosis and Photodynamic Therapy 10:4, pages 399-409.
Crossref
Claudia Weidensteiner, Wilfried Reichardt, Paul J. Shami, Joseph E. Saavedra, Larry K. Keefer, Brunhilde Baumer, Anna Werres, Robert Jasinski, Nadja Osterberg & Astrid Weyerbrock. (2013) Effects of the nitric oxide donor JS-K on the blood-tumor barrier and on orthotopic U87 rat gliomas assessed by MRI. Nitric Oxide 30, pages 17-25.
Crossref
Astrid Weyerbrock, Nadja Osterberg, Nikolaos Psarras, Brunhilde Baumer, Evangelos Kogias, Anna Werres, Stefanie Bette, Joseph E. Saavedra, Larry K. Keefer & Anna Papazoglou. (2012) JS-K, a Glutathione S-Transferase?Activated Nitric Oxide Donor With Antineoplastic Activity in Malignant Gliomas. Neurosurgery 70:2, pages 497-510.
Crossref
Wael Saleem, Yoshiyuki Suzuki, Abdulelah Mobaraki, Yukari Yoshida, Shinei Noda, Jun‐ich Saitoh & Takashi Nakano. (2011) Reduction of nitric oxide level enhances the radiosensitivity of hypoxic non‐small cell lung cancer. Cancer Science 102:12, pages 2150-2156.
Crossref
Susanne Herbst, Ulrich E. Schaible & Bianca E. Schneider. (2011) Interferon Gamma Activated Macrophages Kill Mycobacteria by Nitric Oxide Induced Apoptosis. PLoS ONE 6:5, pages e19105.
Crossref
Qunli Cheng, Filip Sedlic, Danijel Pravdic, Zeljko J. Bosnjak & Wai-Meng Kwok. (2011) Biphasic effect of nitric oxide on the cardiac voltage-dependent anion channel. FEBS Letters 585:2, pages 328-334.
Crossref
Sang-Jin HaWeon Kim. (2010) Mechanism of Ischemia and Reperfusion Injury to the Heart: From the Viewpoint of Nitric Oxide and Mitochondria. Chonnam Medical Journal 46:3, pages 129.
Crossref
Hirofumi Fujita, Daisuke Shiva, Toshihiko Utsumi, Tetsuya Ogino, Tomohiro Ogawa, Koichi Abe, Tatsuji Yasuda, Kozo Utsumi & Junzo Sasaki. (2009) α-Tocopheryl succinate induces rapid and reversible phosphatidylserine externalization in histiocytic lymphoma through the caspase-independent pathway. Molecular and Cellular Biochemistry 333:1-2, pages 137-149.
Crossref
Takashi Amo, Noriaki Kawanishi, Masataka Uchida, Hirofumi Fujita, Eri Oyanagi, Toshihiko Utsumi, Tetsuya Ogino, Keiji Inoue, Taro Shuin, Kozo Utsumi & Junzo Sasaki. (2009) Mechanism of cell death by 5‐aminolevulinic acid‐based photodynamic action and its enhancement by ferrochelatase inhibitors in human histiocytic lymphoma cell line U937. Cell Biochemistry and Function 27:8, pages 503-515.
Crossref
Rui Zhao, Da-Wei Guan, Wei Zhang, Yu Du, Chang-Yan Xiong, Bao-Li Zhu & Jian-Jun Zhang. (2009) Increased expressions and activations of apoptosis-related factors in cell signaling during incised skin wound healing in mice: A preliminary study for forensic wound age estimation. Legal Medicine 11, pages S155-S160.
Crossref
Hirofumi Fujita, Masahiko Shiosaka, Tetsuya Ogino, Yuya Okimura, Toshihiko Utsumi, Eisuke F. Sato, Reiko Akagi, Masayasu Inoue, Kozo Utsumi & Junzo Sasaki. (2008) ?-Lipoic acid suppresses 6-hydroxydopamine-induced ROS generation and apoptosis through the stimulation of glutathione synthesis but not by the expression of heme oxygenase-1. Brain Research 1206, pages 1-12.
Crossref
Lindsay S. BurwellPaul S. Brookes. (2008) Mitochondria as a Target for the Cardioprotective Effects of Nitric Oxide in Ischemia–Reperfusion Injury. Antioxidants & Redox Signaling 10:3, pages 579-600.
Crossref
Sung Won Lee, Yeon Suk Song, Sang Hwa Shin, Kyung Taek Kim, Young Chul Park, Bong Soo Park, Il Yun, Kunhong Kim, Sang Yeob Lee, Won Tae Chung, Hye Jeong Lee & Young Hyun Yoo. (2008) Cilostazol protects rat chondrocytes against nitric oxide–induced apoptosis in vitro and prevents cartilage destruction in a rat model of osteoarthritis. Arthritis & Rheumatism 58:3, pages 790-800.
Crossref
John C. Stavridis. 2008. Oxidation: The Cornerstone of Carcinogenesis. Oxidation: The Cornerstone of Carcinogenesis 63 96 .
Su He Wang, Mary Van Antwerp, Rork Kuick, Paul G. Gauger, Gerard M. Doherty, Yang Yi Fan & James R. BakerJr.Jr.. (2007) Microarray Analysis of Cytokine Activation of Apoptosis Pathways in the Thyroid. Endocrinology 148:10, pages 4844-4852.
Crossref
Masahiro OkouchiOleksandr EkshyyanMagdalena MaracineTak Yee Aw. (2007) Neuronal Apoptosis in Neurodegeneration. Antioxidants & Redox Signaling 9:8, pages 1059-1096.
Crossref
Vidya Udupi, Margaret Yu, Swati Malaviya, Joseph E. Saavedra & Paul J. Shami. (2006) JS-K, a nitric oxide prodrug, induces cytochrome c release and caspase activation in HL-60 myeloid leukemia cells. Leukemia Research 30:10, pages 1279-1283.
Crossref
Hirofumi Fujita, Tetsuya Ogino, Hirotsugu Kobuchi, Takuzo Fujiwara, Hiromi Yano, Jitsuo Akiyama, Kozo Utsumi & Junzo Sasaki. (2006) Cell-permeable cAMP analog suppresses 6-hydroxydopamine-induced apoptosis in PC12 cells through the activation of the Akt pathway. Brain Research 1113:1, pages 10-23.
Crossref
Lyudmila I. Rachek, Valentina I. Grishko, Susan P. LeDoux & Glenn L. Wilson. (2006) Role of nitric oxide-induced mtDNA damage in mitochondrial dysfunction and apoptosis. Free Radical Biology and Medicine 40:5, pages 754-762.
Crossref
Hye Joung Choi, Su-Bog Yee, Sang Eun Park, Eunok Im, Jee Hyung Jung, Hae Young Chung, Yung Hyun Choi & Nam Deuk Kim. (2006) Petrotetrayndiol A induces cell cycle arrest and apoptosis in SK-MEL-2 human melanoma cells through cytochrome c-mediated activation of caspases. Cancer Letters 232:2, pages 214-225.
Crossref
Rosa Zaragozá, Vicente J. Miralles, A. Diana Rus, Concha García, Rafael Carmena, Elena R. García-Trevijano, Teresa Barber, Federico V. Pallardó, Luís Torres & Juan R. Viña. (2005) Weaning induces NOS-2 expression through NF-κB modulation in the lactating mammary gland: importance of GSH. Biochemical Journal 391:3, pages 581-588.
Crossref
Chun-Qi Li & Gerald N. Wogan. (2005) Nitric oxide as a modulator of apoptosis. Cancer Letters 226:1, pages 1-15.
Crossref
Daniel D. MELLEYTimothy W. EVANSGregory J. QUINLAN. (2005) Redox regulation of neutrophil apoptosis and the systemic inflammatory response syndrome. Clinical Science 108:5, pages 413-424.
Crossref
Bernhard Brüne. (2005) The Intimate Relation Between Nitric Oxide and Superoxide in Apoptosis and Cell Survival. Antioxidants & Redox Signaling 7:3-4, pages 497-507.
Crossref
Rajakrishnan Veluthakal, Rajesh Amin & Anjaneyulu Kowluru. (2004) Interleukin-1β induces posttranslational carboxymethylation and alterations in subnuclear distribution of lamin B in insulin-secreting RINm5F cells. American Journal of Physiology-Cell Physiology 287:4, pages C1152-C1162.
Crossref
Josefa Leon, Dario Acuña-Castroviejo, Rosa M Sainz, Juan C Mayo, Dun-Xian Tan & Russel J Reiter. (2004) Melatonin and mitochondrial function. Life Sciences 75:7, pages 765-790.
Crossref
Muriel Cuendet, Konstantin Christov, Daniel D. Lantvit, Yunfan Deng, Samad Hedayat, Lawrence Helson, James D. McChesney & John M. Pezzuto. (2004) Multiple Myeloma Regression Mediated by Bruceantin. Clinical Cancer Research 10:3, pages 1170-1179.
Crossref
Muriel Cuendet & John M. Pezzuto. (2003) Antitumor Activity of Bruceantin:  An Old Drug with New Promise , . Journal of Natural Products 67:2, pages 269-272.
Crossref
Jing‐Qiong Kang, Zhao Zhong Chong & Kenneth Maiese. (2003) Akt1 protects against inflammatory microglial activation through maintenance of membrane asymmetry and modulation of cysteine protease activity. Journal of Neuroscience Research 74:1, pages 37-51.
Crossref
Jing-Qiong Kang, Zhao Zhong Chong & Kenneth Maiese. (2003) Critical Role for Akt1 in the Modulation of Apoptotic Phosphatidylserine Exposure and Microglial Activation. Molecular Pharmacology 64:3, pages 557-569.
Crossref
Bernhard Brüne. (2003) Nitric oxide: NO apoptosis or turning it ON?. Cell Death & Differentiation 10:8, pages 864-869.
Crossref
M Laura Fernández, M Mercedes Iglesias, Verónica A Biron & Carlota Wolfenstein-Todel. (2003) Protective effect of prolactin and placental lactogen on NO-induced Nb2 lymphoma cell apoptosis. Archives of Biochemistry and Biophysics 416:2, pages 249-256.
Crossref
Kayo Arita, Yorihiro Yamamoto, Yoshiki Takehara, Toshihiko Utsumi, Tomoko Kanno, Chosei Miyaguchi, Jitsuo Akiyama, Tamotsu Yoshioka & Kozo Utsumi. (2003) Mechanisms of enhanced apoptosis in HL-60 cells by UV-irradiated n-3 and n-6 polyunsaturated fatty acids. Free Radical Biology and Medicine 35:2, pages 189-199.
Crossref
E L Taylor, I L Megson, C Haslett & A G Rossi. (2003) Nitric oxide: a key regulator of myeloid inflammatory cell apoptosis. Cell Death & Differentiation 10:4, pages 418-430.
Crossref
N.P Konovalova, S.A Goncharova, L.M Volkova, T.A Rajewskaya, L.T Eremenko & A.M Korolev. (2003) Nitric oxide donor increases the efficiency of cytostatic therapy and retards the development of drug resistance. Nitric Oxide 8:1, pages 59-64.
Crossref
O.I. Podgornaya, A.P. Voronin, N.I. Enukashvily, I.V. Matveev & I.B. Lobov. 2003. 227 296 .
Zhao Zhong Chong, Jing-Qiong Kang & Kenneth Maiese. 2003. Neuronal and Vascular Plasticity. Neuronal and Vascular Plasticity 257 298 .
Sruti Shiva, Anna-Liisa Levonen, Maria Cecilia Barone & Victor M. Darley-Usmar. 2003. Signal Transduction by Reactive Oxygen and Nitrogen Species: Pathways and Chemical Principles. Signal Transduction by Reactive Oxygen and Nitrogen Species: Pathways and Chemical Principles 275 290 .
Anup Ramachandran, Anna-Liisa Levonen, Paul S. Brookes, Erin Ceaser, Sruti Shiva, Maria Cecilia Barone & Victor Darley-Usmar. (2002) Mitochondria, nitric oxide, and cardiovascular dysfunction. Free Radical Biology and Medicine 33:11, pages 1465-1474.
Crossref
Guy C Brown & Vilmante Borutaite. (2002) Nitric oxide inhibition of mitochondrial respiration and its role in cell death. Free Radical Biology and Medicine 33:11, pages 1440-1450.
Crossref
M. Tsuchiya, A. Asada, K. Arita, T. Utsumi, T. Yoshida, E. F. Sato, K. Utsumi & M. Inoue. (2002) Induction and mechanism of apoptotic cell death by propofol in HL‐60 cells. Acta Anaesthesiologica Scandinavica 46:9, pages 1068-1074.
Crossref
Anup Ramachandran, Douglas R. Moellering, Erin Ceaser, Sruti Shiva, Jun Xu & Victor Darley-Usmar. (2002) Inhibition of mitochondrial protein synthesis results in increased endothelial cell susceptibility to nitric oxide-induced apoptosis. Proceedings of the National Academy of Sciences 99:10, pages 6643-6648.
Crossref
Zhao Zhong Chong, Jing-Qiong Kang & Kenneth Maiese. (2016) Hematopoietic Factor Erythropoietin Fosters Neuroprotection through Novel Signal Transduction Cascades. Journal of Cerebral Blood Flow & Metabolism 22:5, pages 503-514.
Crossref
Takashi Furuno, Tomoko Kanno, Kayo Arita, Maki Asami, Toshihiko Utsumi, Yoshinori Doi, Masayasu Inoue & Kozo Utsumi. (2001) Roles of long chain fatty acids and carnitine in mitochondrial membrane permeability transition11Abbreviations: CsA, cyclosporin A; Cyt. c, cytochrome c; FBS, fetal bovine serum; Pal-CoA, palmitoyl-CoA; Pi, inorganic phosphate; LCFA, long chain fatty acid; MPT, membrane permeability transition; PLA2, phospholipase A2; RCR, respiratory control ratio; and T3, 3,3′,5-triiodothyronine.. Biochemical Pharmacology 62:8, pages 1037-1046.
Crossref
Shougang Zhuang, John T Demirs & Irene E Kochevar. (2001) Protein kinase C inhibits singlet oxygen-induced apoptosis by decreasing caspase-8 activation. Oncogene 20:46, pages 6764-6776.
Crossref
Akihiko Kashiwagi, Tomoko Kanno, Kayo Arita, Rumi Ishisaka, Toshihiko Utsumi & Kozo Utsumi. (2001) Suppression of T3- and fatty acid-induced membrane permeability transition by l-carnitine. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 130:3, pages 411-418.
Crossref
Kayo Arita, Hirotsugu Kobuchi, Toshihiko Utsumi, Yoshiki Takehara, Jitsuo Akiyama, Alan A Horton & Kozo Utsumi. (2001) Mechanism of apoptosis in HL-60 cells induced by n-3 and n-6 polyunsaturated fatty acids 1 1Abbreviations: AA, arachidonic acid; CsA, cyclosporin A; Cyt.c, cytochrome c; DCFH-DA, 2′,7′-dichlorofluorescein diacetate; DPA, docosapentaenoic acid; EPA, eicosapentaenoic acid; HE, hydroethidine; JC-1, 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazol carbocyanine iodide; MPT, membrane permeability transition; PUFA, polyunsaturated fatty acid; ROS, reactive oxygen species; and z-VAD-fmk, z-Val-Ala-Asp(OMe)-fluoromethylketone.. Biochemical Pharmacology 62:7, pages 821-828.
Crossref
Peter K.M Kim, Ruben Zamora, Patricia Petrosko & Timothy R Billiar. (2001) The regulatory role of nitric oxide in apoptosis. International Immunopharmacology 1:8, pages 1421-1441.
Crossref
Kayo Arita, Toshihiko Utsumi, Akio Kato, Tomoko Kanno, Hirotsugu Kobuchi, Bunji Inoue, Jitsuo Akiyama & Kozo Utsumi. (2000) Mechanism of dibucaine-induced apoptosis in promyelocytic leukemia cells (HL-60). Biochemical Pharmacology 60:7, pages 905-915.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.