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Ryo Koizumi, Taiki Fushimi, Yuki Sato, Yasuyuki Fujii, Hiroki Sato & Naomi Osakabe. (2021) Relationship between hemodynamic alteration and sympathetic nerve activation following a single oral dose of cinnamtannin A2. Free Radical Research 55:5, pages 491-498.
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Banafsheh Jafari Azad, Elnaz Daneshzad, Ali Pasha Meysamie & Fariba Koohdani. (2021) Chronic and acute effects of cocoa products intake on arterial stiffness and platelet count and function: A systematic review and dose-response Meta-analysis of randomized clinical trials. Critical Reviews in Food Science and Nutrition 61:3, pages 357-379.
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Joanna Oracz, Ewa Nebesny, Dorota Zyzelewicz, Grazyna Budryn & Boguslawa Luzak. (2020) Bioavailability and metabolism of selected cocoa bioactive compounds: A comprehensive review. Critical Reviews in Food Science and Nutrition 60:12, pages 1947-1985.
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Asma Babar, Emmanuel Bujold, Vicky Leblanc, Élise Lavoie-Lebel, Joalee Paquette, Laurent Bazinet, Simone Lemieux, Isabelle Marc, Belkacem Abdous & Sylvie Dodin. (2018) Changes in endothelial function, arterial stiffness and blood pressure in pregnant women after consumption of high-flavanol and high-theobromine chocolate: a double blind randomized clinical trial. Hypertension in Pregnancy 37:2, pages 68-80.
Read now
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Khushwant S. Bhullar & H. P. Vasantha Rupasinghe. (2016) Partridgeberry polyphenols protect rat primary cortical neurons from oxygen–glucose deprivation–reperfusion-induced injury via suppression of inflammatory adipokines and regulation of HIF-1α and PPARγ. Nutritional Neuroscience 19:6, pages 260-268.
Read now
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Jiyoung Kim, Jaekyoon Kim, Jaesung Shim, Chang
Yong Lee, Ki
Won Lee & Hyong
Joo Lee. (2014) Cocoa Phytochemicals: Recent Advances in Molecular Mechanisms on Health. Critical Reviews in Food Science and Nutrition 54:11, pages 1458-1472.
Read now
Read now
Susana González-Manzano, Montserrat Dueñas, Felipe Surco-Laos, María Hidalgo, Ana González-Paramas, Celestino Santos-Buelga & Sonia de Pascual-Teresa. (2011)
In vitro evaluation of the antioxidant and anti-inflammatory activities of sulphated metabolites of catechins
Evaluación in vitro de las actividades antioxidante y antiinflamatoria de metabolitos sulfatados de catequinas. CyTA - Journal of Food 9:4, pages 257-264.
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M.S. Fernandez-Panchon, D. Villano, A.M. Troncoso & M.C. Garcia-Parrilla. (2008) Antioxidant Activity of Phenolic Compounds: From In Vitro Results to In Vivo Evidence. Critical Reviews in Food Science and Nutrition 48:7, pages 649-671.
Read now
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Davekanand Gossai & Cesar
A. Lau‐Cam. (2006) Simple HPLC Method, with Fluorometric Detection, for Studying the Oral Absorption of Monomeric Catechins in a Small Animal Model. Journal of Liquid Chromatography & Related Technologies 29:17, pages 2571-2586.
Read now
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Midori Natsume, Naomi Osakabe, Akiko Yasuda, Seigo Baba, Takashi Tokunaga, Kazuo Kondo, Toshihiko Osawa & Junji Terao. (2004) In Vitro Antioxidative Activity of (−)-Epicatechin Glucuronide Metabolites Present in Human and Rat Plasma. Free Radical Research 38:12, pages 1341-1348.
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Peter C.H. Hollman. (2004) Absorption, Bioavailability, and Metabolism of Flavonoids. Pharmaceutical Biology 42:sup1, pages 74-83.
Read now
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Shufeng Zhou, Lee Yong Lim & Balram Chowbay. (2004) Herbal Modulation of P‐Glycoprotein. Drug Metabolism Reviews 36:1, pages 57-104.
Read now
Read now
Carl L. Keen. (2001) Chocolate: Food as Medicine/Medicine as Food. Journal of the American College of Nutrition 20:sup5, pages 436S-439S.
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Articles from other publishers (177)
Kamila Sabino Batista, Marcos dos Santos Lima, Adriano Francisco Alves, Hassler Clementino Cavalcante, Danielle Melo de Souza, Guilherme Costa de Oliveira, Lydiane Tavares Toscano, Alexandre Sérgio Silva, Josuel Feitosa Rodrigues, Bruno Raniere Lins de Albuquerque Meireles, Angela Maria Tribuzy de Magalhães Cordeiro, Darlene Camati Persuhn & Jailane de Souza Aquino. (2023) Antioxidant potential of acerola by-product along the enterohepatic axis of rats fed a high-fat diet. Food Research International 173, pages 113380.
Crossref
Crossref
Priaunsh Dutt, Yashika Shadija, Sneha Dokhale, Sweta Das, Shine Devarajan & Samiksha Garse. 2023. Polyphenols. Polyphenols
343
360
.
Taiki Fushimi, Chie Hirahata, Kento Hiroki, Yasuyuki Fujii, Vittorio Calabrese, Yoshitomo Suhara & Naomi Osakabe. (2023) Activation of transient receptor potential channels is involved in reactive oxygen species (ROS)-dependent regulation of blood flow by (-)-epicatechin tetramer cinnamtannin A2. Biochemical Pharmacology 214, pages 115682.
Crossref
Crossref
Ana Lucía Mayorga-Gross & Alexander Montoya-Arroyo. 2023. Functional Foods and Their Implications for Health Promotion. Functional Foods and Their Implications for Health Promotion
55
95
.
Elodie Jean-Marie, Weiwen Jiang, Didier Bereau & Jean-Charles Robinson. (2022) Theobroma cacao and Theobroma grandiflorum: Botany, Composition and Pharmacological Activities of Pods and Seeds. Foods 11:24, pages 3966.
Crossref
Crossref
Lisard Iglesias-Carres, Kathryn C. Racine & Andrew P. Neilson. (2022)
Phenolic-rich beverages reduce bacterial TMA formation in an
ex vivo
–
in vitro
colonic fermentation model
. Food & Function 13:15, pages 8022-8037.
Crossref
Crossref
Sharmistha Samanta, Tanmay Sarkar, Runu Chakraborty, Maksim Rebezov, Mohammad Ali Shariati, Muthu Thiruvengadam & Kannan R.R. Rengasamy. (2022) Dark chocolate: An overview of its biological activity, processing, and fortification approaches. Current Research in Food Science 5, pages 1916-1943.
Crossref
Crossref
Yuko Ishii, Orie Muta, Tomohiro Teshima, Nayuta Hirasima, Minayu Odaka, Taiki Fushimi, Yasuyuki Fujii & Naomi Osakabe. (2021) Repeated Oral Administration of Flavan-3-ols Induces Browning in Mice Adipose Tissues through Sympathetic Nerve Activation. Nutrients 13:12, pages 4214.
Crossref
Crossref
Oskar Wiśniewski, Aleksander Rajczewski, Agnieszka Szumigała & Magdalena Gibas-Dorna. (2021) Diet-Induced Adipocyte Browning. Polish Journal of Food and Nutrition Sciences, pages 353-381.
Crossref
Crossref
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Crossref
Crossref
Anouk Tanghe, Elsa Heyman, Karsten Vanden Wyngaert, Ans Van Ginckel, Bert Celie, Ernst Rietzschel, Patrick Calders & Samyah Shadid. (2021) Evaluation of blood pressure lowering effects of cocoa flavanols in diabetes mellitus: A systematic review and meta-analysis. Journal of Functional Foods 79, pages 104399.
Crossref
Crossref
Olga Rojo-Poveda, Letricia Barbosa-Pereira, Charaf El Khattabi, Estelle N.H. Youl, Marta Bertolino, Cédric Delporte, Stéphanie Pochet & Caroline Stévigny. (2020) Polyphenolic and Methylxanthine Bioaccessibility of Cocoa Bean Shell Functional Biscuits: Metabolomics Approach and Intestinal Permeability through Caco-2 Cell Models. Antioxidants 9:11, pages 1164.
Crossref
Crossref
Sanami Kobayashi, Chika Nanayama, Noriko Ogawa, Naoyuki Matsumoto & Masato Nishiwaki. (2020) Effects of regular green tea intake on body fat and arterial stiffness in young adults: A randomized intervention study継続的な緑茶の摂取が若年者の体脂肪と動脈スティフネスに及ぼす影響 −無作為割り付け介入試験−. Japanese Journal of Physical Fitness and Sports Medicine 69:3, pages 249-259.
Crossref
Crossref
Monica Michicotl Meneses & María Eugenia Jaramillo Flores. 2020. Flavonoids - A Coloring Model for Cheering up Life. Flavonoids - A Coloring Model for Cheering up Life.
Miren Gómez-Juaristi, Beatriz Sarria, Sara Martínez-López, Laura Bravo Clemente & Raquel Mateos. (2019) Flavanol Bioavailability in Two Cocoa Products with Different Phenolic Content. A Comparative Study in Humans. Nutrients 11:7, pages 1441.
Crossref
Crossref
Ana Lucía Mayorga-Gross & Patricia Esquivel. (2019) Impact of Cocoa Products Intake on Plasma and Urine Metabolites: A Review of Targeted and Non-Targeted Studies in Humans. Nutrients 11:5, pages 1163.
Crossref
Crossref
Masato Nishiwaki, Yuri Nakano & Naoyuki Matsumoto. (2019) Effects of regular high-cocoa chocolate intake on arterial stiffness and metabolic characteristics during exercise. Nutrition 60, pages 53-58.
Crossref
Crossref
Thaíse Maria Nogueira Mendes, Yukihisa Murayama, Natsumi Yamaguchi, Geni Rodrigues Sampaio, Luciana Cristina Brigatto Fontes, Elizabeth Aparecida Ferraz da Silva Torres, Hirotoshi Tamura & Lina Yonekura. (2019) Guaraná (Paullinia cupana) catechins and procyanidins: Gastrointestinal/colonic bioaccessibility, Caco-2 cell permeability and the impact of macronutrients. Journal of Functional Foods 55, pages 352-361.
Crossref
Crossref
Wan NurFarahin Wan Osman, Nur Adeelah Che Ahmad Tantowi, Seng Fong Lau & Suhaila Mohamed. (2019)
Epicatechin and scopoletin rich
Morinda citrifolia
(Noni) leaf extract supplementation, mitigated Osteoarthritis via anti-inflammatory, anti-oxidative, and anti-protease pathways
. Journal of Food Biochemistry 43:3, pages e12755.
Crossref
Crossref
Kyuichi Kawabata, Yasukiyo Yoshioka & Junji Terao. (2019) Role of Intestinal Microbiota in the Bioavailability and Physiological Functions of Dietary Polyphenols. Molecules 24:2, pages 370.
Crossref
Crossref
Martha del Pilar López Hernández, Jenifer Criollo Núñez, María Soledad Hernández Gómez & María Denis Lozano Tovar. (2019) Physicochemical and microbiological dynamics of the fermentation of the ccn51 cocoa material in three maturity stages. Revista Brasileira de Fruticultura 41:3.
Crossref
Crossref
Monika Prakash, B.V. Basavaraj & K.N. Chidambara Murthy. (2019) Biological functions of epicatechin: Plant cell to human cell health. Journal of Functional Foods 52, pages 14-24.
Crossref
Crossref
Charlotte C. J. R. Michielsen, Enrique Almanza-Aguilera, Elske M. Brouwer-Brolsma, Mireia Urpi-Sarda & Lydia A. Afman. (2018) Biomarkers of food intake for cocoa and liquorice (products): a systematic review. Genes & Nutrition 13:1.
Crossref
Crossref
Gary Williamson, Colin D. Kay & Alan Crozier. (2018) The Bioavailability, Transport, and Bioactivity of Dietary Flavonoids: A Review from a Historical Perspective. Comprehensive Reviews in Food Science and Food Safety 17:5, pages 1054-1112.
Crossref
Crossref
Gina Borges, Javier I. Ottaviani, Justin J.J. van der Hooft, Hagen Schroeter & Alan Crozier. (2018) Absorption, metabolism, distribution and excretion of (−)-epicatechin: A review of recent findings. Molecular Aspects of Medicine 61, pages 18-30.
Crossref
Crossref
Marija Marinko, Goran Jankovic, Dragoslav Nenezic, Predrag Milojevic, Ivan Stojanovic, Vladimir Kanjuh & Aleksandra Novakovic. (2018)
(−)-Epicatechin-induced relaxation of isolated human saphenous vein: Roles of K
+
and Ca
2+
channels
. Phytotherapy Research 32:2, pages 267-275.
Crossref
Crossref
Duane D. Mellor, Daniel Amund, Ekavi Georgousopoulou & Nenad Naumovski. (2017) Sugar and cocoa: sweet synergy or bitter antagonisms. Formulating cocoa and chocolate products for health: a narrative review. International Journal of Food Science & Technology 53:1, pages 33-42.
Crossref
Crossref
Thomas J. RowleyIVIV, Benjamin F. Bitner, Jason D. Ray, Daniel R. Lathen, Andrew T. Smithson, Blake W. Dallon, Chase J. Plowman, Benjamin T. Bikman, Jason M. Hansen, Melanie R. Dorenkott, Katheryn M. Goodrich, Liyun Ye, Sean F. O'Keefe, Andrew P. Neilson & Jeffery S. Tessem. (2017) Monomeric cocoa catechins enhance β-cell function by increasing mitochondrial respiration. The Journal of Nutritional Biochemistry 49, pages 30-41.
Crossref
Crossref
Maria Angeles Martin, Luis Goya & Sonia Ramos. (2017) Protective effects of tea, red wine and cocoa in diabetes. Evidences from human studies. Food and Chemical Toxicology 109, pages 302-314.
Crossref
Crossref
Ahmed Bettaieb, Eleonora Cremonini, Heeteak Kang, Jiye Kang, Fawaz G. Haj & Patricia I. Oteiza. (2016) Anti-inflammatory actions of (−)-epicatechin in the adipose tissue of obese mice. The International Journal of Biochemistry & Cell Biology 81, pages 383-392.
Crossref
Crossref
Akiko Saito, Kodai Inagawa, Rikihiko Ebe, Shinobu Fukase, Yukari Horikoshi, Masahiro Shibata & Naomi Osakabe. (2016) Onset of a hypotensive effect following ingestion of flavan 3-ols involved in the activation of adrenergic receptors. Free Radical Biology and Medicine 99, pages 584-592.
Crossref
Crossref
Karen M. Strat, Thomas J. RowleyIVIV, Andrew T. Smithson, Jeffery S. Tessem, Matthew W. Hulver, Dongmin Liu, Brenda M. Davy, Kevin P. Davy & Andrew P. Neilson. (2016) Mechanisms by which cocoa flavanols improve metabolic syndrome and related disorders. The Journal of Nutritional Biochemistry 35, pages 1-21.
Crossref
Crossref
Maria Ángeles Martin, Luis Goya & Sonia Ramos. (2016) Antidiabetic actions of cocoa flavanols. Molecular Nutrition & Food Research 60:8, pages 1756-1769.
Crossref
Crossref
Yaxi Hu, Zhi Jie Pan, Wen Liao, Jiaqi Li, Pierre Gruget, David D. Kitts & Xiaonan Lu. (2016) Determination of antioxidant capacity and phenolic content of chocolate by attenuated total reflectance-Fourier transformed-infrared spectroscopy. Food Chemistry 202, pages 254-261.
Crossref
Crossref
Luis Goya, María Martín, Beatriz Sarriá, Sonia Ramos, Raquel Mateos & Laura Bravo. (2016) Effect of Cocoa and Its Flavonoids on Biomarkers of Inflammation: Studies of Cell Culture, Animals and Humans. Nutrients 8:4, pages 212.
Crossref
Crossref
Naoya Kamio, Takuma Suzuki, Yuto Watanabe, Yoshitomo Suhara & Naomi Osakabe. (2016) A single oral dose of flavan-3-ols enhances energy expenditure by sympathetic nerve stimulation in mice. Free Radical Biology and Medicine 91, pages 256-263.
Crossref
Crossref
Maria Ángeles Martin, Luis Goya & Sonia Ramos. 2016. Molecular Nutrition and Diabetes. Molecular Nutrition and Diabetes
183
196
.
Kade Davison & Peter R. C. Howe. (2015) Potential Implications of Dose and Diet for the Effects of Cocoa Flavanols on Cardiometabolic Function. Journal of Agricultural and Food Chemistry 63:45, pages 9942-9947.
Crossref
Crossref
Tania Cifuentes-Gomez, Ana Rodriguez-Mateos, Isidro Gonzalez-Salvador, María Elena Alañon & Jeremy P. E. Spencer. (2015) Factors Affecting the Absorption, Metabolism, and Excretion of Cocoa Flavanols in Humans. Journal of Agricultural and Food Chemistry 63:35, pages 7615-7623.
Crossref
Crossref
Telma C. Contreras, Elisabetta Ricciardi, Eleonora Cremonini & Patricia I. Oteiza. (2015) (−)-Epicatechin in the prevention of tumor necrosis alpha-induced loss of Caco-2 cell barrier integrity. Archives of Biochemistry and Biophysics 573, pages 84-91.
Crossref
Crossref
Ilaria Peluso, Maura Palmery & Mauro Serafini. (2015) Effect of cocoa products and flavanols on platelet aggregation in humans: a systematic review. Food & Function 6:7, pages 2128-2134.
Crossref
Crossref
Naoki Watanabe, Kodai Inagawa, Masahiro Shibata & Naomi Osakabe. (2014) Flavan-3-ol fraction from cocoa powder promotes mitochondrial biogenesis in skeletal muscle in mice. Lipids in Health and Disease 13:1.
Crossref
Crossref
Jaime Andres Mogollon, Catherine Boivin, Simone Lemieux, Claudine Blanchet, Joël Claveau & Sylvie Dodin. (2014) Chocolate flavanols and skin photoprotection: a parallel, double-blind, randomized clinical trial. Nutrition Journal 13:1.
Crossref
Crossref
Yusuke Matsumura, Yuta Nakagawa, Katsuyuki Mikome, Hiroki Yamamoto & Naomi Osakabe. (2014) Enhancement of Energy Expenditure following a Single Oral Dose of Flavan-3-Ols Associated with an Increase in Catecholamine Secretion. PLoS ONE 9:11, pages e112180.
Crossref
Crossref
Naomi Osakabe, Junpei Hoshi, Naoto Kudo & Masahiro Shibata. (2014) The flavan-3-ol fraction of cocoa powder suppressed changes associated with early-stage metabolic syndrome in high-fat diet-fed rats. Life Sciences 114:1, pages 51-56.
Crossref
Crossref
Anurag Singh, Audrey Demont, Lucas Actis-Goretta, Sébastien Holvoet, Antoine Lévêques, Melissa Lepage, Sophie Nutten & Annick Mercenier. (2014) Identification of epicatechin as one of the key bioactive constituents of polyphenol-enriched extracts that demonstrate an anti-allergic effect in a murine model of food allergy. British Journal of Nutrition 112:3, pages 358-368.
Crossref
Crossref
Ana Faria, Manuela Meireles, Iva Fernandes, Celestino Santos-Buelga, Susana Gonzalez-Manzano, Montserrat Dueñas, Victor de Freitas, Nuno Mateus & Conceição Calhau. (2014) Flavonoid metabolites transport across a human BBB model. Food Chemistry 149, pages 190-196.
Crossref
Crossref
Sheila G. West, Molly D. McIntyre, Matthew J. Piotrowski, Nathalie Poupin, Debra L. Miller, Amy G. Preston, Paul Wagner, Lisa F. Groves & Ann C. Skulas-Ray. (2013) Effects of dark chocolate and cocoa consumption on endothelial function and arterial stiffness in overweight adults. British Journal of Nutrition 111:4, pages 653-661.
Crossref
Crossref
Nasiruddin Khan, Olha Khymenets, Mireia Urpí-Sardà, Sara Tulipani, Mar Garcia-Aloy, María Monagas, Ximena Mora-Cubillos, Rafael Llorach & Cristina Andres-Lacueva. (2014) Cocoa Polyphenols and Inflammatory Markers of Cardiovascular Disease. Nutrients 6:2, pages 844-880.
Crossref
Crossref
Naomi Osakabe. 2014. Polyphenols in Human Health and Disease. Polyphenols in Human Health and Disease
963
970
.
Rakesh Sharma. 2014. Polyphenols in Human Health and Disease. Polyphenols in Human Health and Disease
757
778
.
Giulia Corona, David Vauzour, Anna Amini & Jeremy P.E. Spencer. 2014. Polyphenols in Human Health and Disease. Polyphenols in Human Health and Disease
591
604
.
Faisal Ali, Amin Ismail & Sander Kersten. (2014) Molecular mechanisms underlying the potential antiobesity-related diseases effect of cocoa polyphenols. Molecular Nutrition & Food Research 58:1, pages 33-48.
Crossref
Crossref
Jaime Andres Mogollon, Emmanuel Bujold, Simone Lemieux, Mélodie Bourdages, Claudine Blanchet, Laurent Bazinet, Charles Couillard, Martin Noël & Sylvie Dodin. (2013) Blood pressure and endothelial function in healthy, pregnant women after acute and daily consumption of flavanol-rich chocolate: a pilot, randomized controlled trial. Nutrition Journal 12:1.
Crossref
Crossref
Wendy J. Hollands, David J. Hart, Jack R. Dainty, Oliver Hasselwander, Kirsti Tiihonen, Richard Wood & Paul A. Kroon. (2013) Bioavailability of epicatechin and effects on nitric oxide metabolites of an apple flavanol‐rich extract supplemented beverage compared to a whole apple puree: a randomized, placebo‐controlled, crossover trial. Molecular Nutrition & Food Research 57:7, pages 1209-1217.
Crossref
Crossref
Maria Angeles Martin, Luis Goya & Sonia Ramos. (2013) Potential for preventive effects of cocoa and cocoa polyphenols in cancer. Food and Chemical Toxicology 56, pages 336-351.
Crossref
Crossref
Rafael Llorach, Mireia Urpi‐Sarda, Sara Tulipani, Mar Garcia‐Aloy, Maria Monagas & Cristina Andres‐Lacueva. (2013) Metabolomic fingerprint in patients at high risk of cardiovascular disease by cocoa intervention. Molecular Nutrition & Food Research 57:6, pages 962-973.
Crossref
Crossref
Paola Vitaglione, Roberta Barone Lumaga, Rosalia Ferracane, Sereno Sellitto, José Ramón Morelló, Jordi Reguant Miranda, Eyal Shimoni & Vincenzo Fogliano. (2012) Human bioavailability of flavanols and phenolic acids from cocoa-nut creams enriched with free or microencapsulated cocoa polyphenols. British Journal of Nutrition 109:10, pages 1832-1843.
Crossref
Crossref
Daniele Del RioAna Rodriguez-MateosJeremy P.E. SpencerMassimiliano TognoliniGina BorgesAlan Crozier. (2013) Dietary (Poly)phenolics in Human Health: Structures, Bioavailability, and Evidence of Protective Effects Against Chronic Diseases. Antioxidants & Redox Signaling 18:14, pages 1818-1892.
Crossref
Crossref
Maarit J. Rein, Mathieu Renouf, Cristina Cruz‐Hernandez, Lucas Actis‐Goretta, Sagar K. Thakkar & Marcia da Silva Pinto. (2013) Bioavailability of bioactive food compounds: a challenging journey to bioefficacy. British Journal of Clinical Pharmacology 75:3, pages 588-602.
Crossref
Crossref
Bernice Wright, Jeremy P. E. Spencer, Julie A. Lovegrove & Jonathan M. Gibbins. (2013) Flavonoid inhibitory pharmacodynamics on platelet function in physiological environments. Food & Function 4:12, pages 1803.
Crossref
Crossref
Manuel Rusconi, Maria Teresa Pinorini & Ario Conti. 2013. Natural Products. Natural Products
2311
2332
.
Rosa M. Lamuela-Raventos, María Izquierdo-Pulido & Ramón Estruch. 2013. Chocolate in Health and Nutrition. Chocolate in Health and Nutrition
119
124
.
Gertraud Maskarinec. 2013. Chocolate in Health and Nutrition. Chocolate in Health and Nutrition
355
367
.
Cesar A. Lau-Cam. 2013. Chocolate in Health and Nutrition. Chocolate in Health and Nutrition
201
246
.
Kevin D. Monahan. (2012) Effect of cocoa/chocolate ingestion on brachial artery flow-mediated dilation and its relevance to cardiovascular health and disease in humans. Archives of Biochemistry and Biophysics 527:2, pages 90-94.
Crossref
Crossref
Marcela A. Vazquez-Prieto, Ahmed Bettaieb, Fawaz G. Haj, César G. Fraga & Patricia I. Oteiza. (2012) (−)-Epicatechin prevents TNFα-induced activation of signaling cascades involved in inflammation and insulin sensitivity in 3T3-L1 adipocytes. Archives of Biochemistry and Biophysics 527:2, pages 113-118.
Crossref
Crossref
Lucas Actis-Goretta, Antoine Lévèques, Francesca Giuffrida, Fedor Romanov-Michailidis, Florian Viton, Denis Barron, Montserrat Duenas-Paton, Susana Gonzalez-Manzano, Celestino Santos-Buelga, Gary Williamson & Fabiola Dionisi. (2012) Elucidation of (−)-epicatechin metabolites after ingestion of chocolate by healthy humans. Free Radical Biology and Medicine 53:4, pages 787-795.
Crossref
Crossref
Sabine Ellinger, Andreas Reusch, Peter Stehle & Hans-Peter Helfrich. (2012) Epicatechin ingested via cocoa products reduces blood pressure in humans: a nonlinear regression model with a Bayesian approach. The American Journal of Clinical Nutrition 95:6, pages 1365-1377.
Crossref
Crossref
S. Saha, W. Hollands, P.W. Needs, L.M. Ostertag, B. de Roos, G.G. Duthie & P.A. Kroon. (2012) Human O-sulfated metabolites of (−)-epicatechin and methyl-(−)-epicatechin are poor substrates for commercial aryl-sulfatases: Implications for studies concerned with quantifying epicatechin bioavailability. Pharmacological Research 65:6, pages 592-602.
Crossref
Crossref
Yui Kau Fong, Chen Rui Li, Siu Kwan Wo, Shu Wang, Limin Zhou, Li Zhang, Ge Lin & Zhong Zuo. (2012) In vitro and in situ evaluation of herb–drug interactions during intestinal metabolism and absorption of Baicalein. Journal of Ethnopharmacology 141:2, pages 742-753.
Crossref
Crossref
Michael Clifford & Daniele Rio. 2012. Flavonoids and Related Compounds. Flavonoids and Related Compounds.
Javier I. Ottaviani, Tony Y. Momma, Gunter K. Kuhnle, Carl L. Keen & Hagen Schroeter. (2012) Structurally related (−)-epicatechin metabolites in humans: Assessment using de novo chemically synthesized authentic standards. Free Radical Biology and Medicine 52:8, pages 1403-1412.
Crossref
Crossref
L.A. Corcuera, S. Amézqueta, L. Arbillaga, A. Vettorazzi, S. Touriño, J.L. Torres & A. López de Cerain. (2012) A polyphenol-enriched cocoa extract reduces free radicals produced by mycotoxins. Food and Chemical Toxicology 50:3-4, pages 989-995.
Crossref
Crossref
N Moghadasian & Mohammed EskinAyyappan Aachary, Usha Thiyam & N Eskin. 2012. Functional Foods and Cardiovascular Disease. Functional Foods and Cardiovascular Disease
233
258
.
Koichi Nakazato & Arata Tsutaki. (2012) Regulatory mechanisms of muscle fiber types and their possible interactions with external nutritional stimuli. The Journal of Physical Fitness and Sports Medicine 1:4, pages 655-664.
Crossref
Crossref
Edwin N. Frankel. 2012. Antioxidants in Food and Biology. Antioxidants in Food and Biology
143
192
.
H Jacobs, G H Koek, R Peters, M Moalin, J Tack, W J van der Vijgh, A Bast & G R Haenen. (2011) Differences in Pharmacological Activities of the Antioxidant Flavonoid MonoHER in Humans and Mice Are Caused by Variations in Its Metabolic Profile. Clinical Pharmacology & Therapeutics 90:6, pages 852-859.
Crossref
Crossref
Francisco Tomás‐Barbéran, Gina Borges & Alan Crozier. 2011. Teas, Cocoa and Coffee. Teas, Cocoa and Coffee
193
217
.
O A Tokede, J M Gaziano & L Djoussé. (2011) Effects of cocoa products/dark chocolate on serum lipids: a meta-analysis. European Journal of Clinical Nutrition 65:8, pages 879-886.
Crossref
Crossref
Cesar G. Fraga & Patricia I. Oteiza. (2011) Dietary flavonoids: Role of (−)-epicatechin and related procyanidins in cell signaling. Free Radical Biology and Medicine 51:4, pages 813-823.
Crossref
Crossref
Mauro Serafini, Daniele Rio, Yao N’Dri, Saverio Bettuzzi & Ilaria Peluso. 2011. Herbal Medicine. Herbal Medicine
239
261
.
Javier I. Ottaviani, Tony Y. Momma, Christian Heiss, Catherine Kwik-Uribe, Hagen Schroeter & Carl L. Keen. (2011) The stereochemical configuration of flavanols influences the level and metabolism of flavanols in humans and their biological activity in vivo. Free Radical Biology and Medicine 50:2, pages 237-244.
Crossref
Crossref
Hagen Schroeter, Christian Heiss, Jeremy P.E. Spencer, Carl L. Keen, Joanne R. Lupton & Harold H. Schmitz. (2010) Recommending flavanols and procyanidins for cardiovascular health: Current knowledge and future needs. Molecular Aspects of Medicine 31:6, pages 546-557.
Crossref
Crossref
Alan Crozier, Daniele Del Rio & Michael N. Clifford. (2010) Bioavailability of dietary flavonoids and phenolic compounds. Molecular Aspects of Medicine 31:6, pages 446-467.
Crossref
Crossref
Ramesh C. Khanal, Luke R. Howard, Samuel E. Wilkes, Theodore J. Rogers & Ronald L. Prior. (2010) Urinary Excretion of (Epi)catechins in Rats Fed Different Berries or Berry Products. Journal of Agricultural and Food Chemistry 58:21, pages 11257-11264.
Crossref
Crossref
Daniele Del Rio, Luca Calani, Chiara Cordero, Sara Salvatore, Nicoletta Pellegrini & Furio Brighenti. (2010) Bioavailability and catabolism of green tea flavan-3-ols in humans. Nutrition 26:11-12, pages 1110-1116.
Crossref
Crossref
Jara Pérez-Jiménez, Jane Hubert, Lee Hooper, Aedin Cassidy, Claudine Manach, Gary Williamson & Augustin Scalbert. (2010) Urinary metabolites as biomarkers of polyphenol intake in humans: a systematic review. The American Journal of Clinical Nutrition 92:4, pages 801-809.
Crossref
Crossref
Daniele Del Rio, Gina Borges & Alan Crozier. (2010) Berry flavonoids and phenolics: bioavailability and evidence of protective effects. British Journal of Nutrition 104:S3, pages S67-S90.
Crossref
Crossref
K Davison, N M Berry, G Misan, A M Coates, J D Buckley & P R C Howe. (2010) Dose-related effects of flavanol-rich cocoa on blood pressure. Journal of Human Hypertension 24:9, pages 568-576.
Crossref
Crossref
Daniele Del Rio, Angelique Stalmach, Luca Calani & Alan Crozier. (2010) Bioavailability of Coffee Chlorogenic Acids and Green Tea Flavan-3-ols. Nutrients 2:8, pages 820-833.
Crossref
Crossref
Gina Borges, William Mullen, Adam Mullan, Michael E. J. Lean, Susan A. Roberts & Alan Crozier. (2010) Bioavailability of multiple components following acute ingestion of a polyphenol-rich juice drink. Molecular Nutrition & Food Research 54:S2, pages S268-S277.
Crossref
Crossref
Christina Ritter, Benno F. Zimmermann & Rudolf Galensa. (2010) Chiral separation of (+)/(−)-catechin from sulfated and glucuronidated metabolites in human plasma after cocoa consumption. Analytical and Bioanalytical Chemistry 397:2, pages 723-730.
Crossref
Crossref
William Mullen, Gina Borges, Michael E. J. Lean, Susan A. Roberts & Alan Crozier. (2010) Identification of Metabolites in Human Plasma and Urine after Consumption of a Polyphenol-Rich Juice Drink. Journal of Agricultural and Food Chemistry 58:4, pages 2586-2595.
Crossref
Crossref
Maria Monagas, Mireia Urpi-Sarda, Fernando Sánchez-Patán, Rafael Llorach, Ignacio Garrido, Carmen Gómez-Cordovés, Cristina Andres-Lacueva & Begoña Bartolomé. (2010) Insights into the metabolism and microbial biotransformation of dietary flavan-3-ols and the bioactivity of their metabolites. Food & Function 1:3, pages 233.
Crossref
Crossref
Monica Galleano, Patricia I Oteiza & Cesar G Fraga. (2009) Cocoa, Chocolate, and Cardiovascular Disease. Journal of Cardiovascular Pharmacology 54:6, pages 483-490.
Crossref
Crossref
Tankred Schewe, Yvonne Steffen, Elisabeth Kravets & Helmut Sies. 2009. Plant Phenolics and Human Health. Plant Phenolics and Human Health
159
164
.
Gerald Rimbach, Mona Melchin, Jennifer Moehring & Anika Wagner. (2009) Polyphenols from Cocoa and Vascular Health—A Critical Review. International Journal of Molecular Sciences 10:10, pages 4290-4309.
Crossref
Crossref
William Mullen, Gina Borges, Jennifer L Donovan, Christine A Edwards, Mauro Serafini, Michael EJ Lean & Alan Crozier. (2009) Milk decreases urinary excretion but not plasma pharmacokinetics of cocoa flavan-3-ol metabolites in humans. The American Journal of Clinical Nutrition 89:6, pages 1784-1791.
Crossref
Crossref
Emma Ramiro-Puig & Margarida Castell. (2009) Cocoa: antioxidant and immunomodulator. British Journal of Nutrition 101:7, pages 931-940.
Crossref
Crossref
Jan Frank, Trevor W. George, John K. Lodge, Ana M. Rodriguez-Mateos, Jeremy P.E. Spencer, Anne Marie Minihane & Gerald Rimbach. (2009) Daily Consumption of an Aqueous Green Tea Extract Supplement Does Not Impair Liver Function or Alter Cardiovascular Disease Risk Biomarkers in Healthy Men. The Journal of Nutrition 139:1, pages 58-62.
Crossref
Crossref
William MullenJean-Max RouanetCyril AugerPierre-Louis TeissèdreStuart T. CaldwellRichard C. HartleyMicheal E. J. LeanChristine A. EdwardsAlan Crozier. (2008)
Bioavailability of [2-
14
C]Quercetin-4′-glucoside in Rats
. Journal of Agricultural and Food Chemistry 56:24, pages 12127-12137.
Crossref
Crossref
Miruais S. Hamed, Steven Gambert, Kevin P. Bliden, Oscar Bailon, Singla Anand, Mark J. Antonino, Fatema Hamed, Udaya S. Tantry & Paul A. Gurbel. (2008) Dark Chocolate Effect on Platelet Activity, C-Reactive Protein and Lipid Profile: A Pilot Study. Southern Medical Journal 101:12, pages 1203-1208.
Crossref
Crossref
Rie Mukai, Itsuko Fukuda, Shin Nishiumi, Midori Natsume, Naomi Osakabe, Ken-ichi Yoshida & Hitoshi Ashida. (2008) Cacao Polyphenol Extract Suppresses Transformation of an Aryl Hydrocarbon Receptor in C57BL/6 Mice. Journal of Agricultural and Food Chemistry 56:21, pages 10399-10405.
Crossref
Crossref
Andrew McShea, Emma Ramiro-Puig, Sandra B Munro, Gemma Casadesus, Margarida Castell & Mark A Smith. (2008) Clinical benefit and preservation of flavonols in dark chocolate manufacturing. Nutrition Reviews 66:11, pages 630-641.
Crossref
Crossref
Abbe Jalil & Amin Ismail. (2008) Polyphenols in Cocoa and Cocoa Products: Is There a Link between Antioxidant Properties and Health?. Molecules 13:9, pages 2190-2219.
Crossref
Crossref
Ramona Mehrinfar & William H. Frishman. (2008) Flavanol-Rich Cocoa. Cardiology in Review 16:3, pages 109-115.
Crossref
Crossref
A. Yasuda, H. Takano, N. Osakabe, C. Sanbongi, K. Fukuda, M. Natsume, R. Yanagisawa, K. Inoue, Y. Kato, T. Osawa & T. Yoshikawa. (2008) Cacao Liquor Proanthocyanidins Inhibit Lung Injury Induced by Diesel Exhaust Particles. International Journal of Immunopathology and Pharmacology 21:2, pages 279-288.
Crossref
Crossref
Midori Natsume, Naomi Osakabe, Akiko Yasuda, Toshihiko Osawa & Junji Terao. (2008) Inhibitory Effects of Conjugated Epicatechin Metabolites on Peroxynitrite-mediated Nitrotyrosine Formation. Journal of Clinical Biochemistry and Nutrition 42:1, pages 50-53.
Crossref
Crossref
Sunday Ene-ojo Atawodi, Beate Pfundstein, Roswitha Haubner, Bertold Spiegelhalder, Helmut Bartsch & Robert Wyn Owen. (2007)
Content of Polyphenolic Compounds in the Nigerian Stimulants Cola nitida ssp.
alba
, Cola nitida ssp.
rubra
A. Chev, and Cola acuminata Schott & Endl and Their Antioxidant Capacity
. Journal of Agricultural and Food Chemistry 55:24, pages 9824-9828.
Crossref
Crossref
Seigo Baba, Midori Natsume, Akiko Yasuda, Yuko Nakamura, Takaaki Tamura, Naomi Osakabe, Minoru Kanegae & Kazuo Kondo. (2007) Plasma LDL and HDL Cholesterol and Oxidized LDL Concentrations Are Altered in Normo- and Hypercholesterolemic Humans after Intake of Different Levels of Cocoa Powder. The Journal of Nutrition 137:6, pages 1436-1441.
Crossref
Crossref
Francisco A. Tomas-Barberán, Elena Cienfuegos-Jovellanos, Alicia Marín, Begoña Muguerza, Angel Gil-Izquierdo, Begoña Cerdá, Pilar Zafrilla, Juana Morillas, Juana Mulero, Alvin Ibarra, María A. Pasamar, Daniel Ramón & Juan Carlos Espín. (2007) A New Process To Develop a Cocoa Powder with Higher Flavonoid Monomer Content and Enhanced Bioavailability in Healthy Humans. Journal of Agricultural and Food Chemistry 55:10, pages 3926-3935.
Crossref
Crossref
Min Jung Kang & Dong-Hyun Kim. 2007. Anti-Angiogenic Functional and Medicinal Foods. Anti-Angiogenic Functional and Medicinal Foods
593
610
.
Howard Epstein. (2007) From the Inside Out: The Moisturol Story Could Have Taken Another Twist. SKINmed 6:2, pages 61-62.
Crossref
Crossref
Seigo Baba, Naomi Osakabe, Yoji Kato, Midori Natsume, Akiko Yasuda, Toshimi Kido, Kumiko Fukuda, Yuko Muto & Kazuo Kondo. (2007) Continuous intake of polyphenolic compounds containing cocoa powder reduces LDL oxidative susceptibility and has beneficial effects on plasma HDL-cholesterol concentrations in humans. The American Journal of Clinical Nutrition 85:3, pages 709-717.
Crossref
Crossref
Christian Heiss, David Finis, Petra Kleinbongard, Arne Hoffmann, Tienush Rassaf, Malte Kelm & Helmut Sies. (2007) Sustained Increase in Flow-Mediated Dilation After Daily Intake of High-Flavanol Cocoa Drink Over 1 Week. Journal of Cardiovascular Pharmacology 49:2, pages 74-80.
Crossref
Crossref
Susan E. Pollard, Gunter G.C. Kuhnle, David Vauzour, Katerina Vafeiadou, Xenofon Tzounis, Matthew Whiteman, Catherine Rice-Evans & Jeremy P.E. Spencer. (2006) The reaction of flavonoid metabolites with peroxynitrite. Biochemical and Biophysical Research Communications 350:4, pages 960-968.
Crossref
Crossref
Joe A. Vinson, John Proch, Pratima Bose, Sean Muchler, Pamela Taffera, Donna Shuta, Najwa Samman & Gabriel A. Agbor. (2006) Chocolate Is a Powerful ex Vivo and in Vivo Antioxidant, an Antiatherosclerotic Agent in an Animal Model, and a Significant Contributor to Antioxidants in the European and American Diets. Journal of Agricultural and Food Chemistry 54:21, pages 8071-8076.
Crossref
Crossref
Janice F. Wang-Polagruto, Amparo C. Villablanca, John A. Polagruto, Luke Lee, Roberta R. Holt, Heather R. Schrader, Jodi L. Ensunsa, Francene M. Steinberg, Harold H. Schmitz & Carl L. Keen. (2006) Chronic Consumption of Flavanol-rich Cocoa Improves Endothelial Function and Decreases Vascular Cell Adhesion Molecule in Hypercholesterolemic Postmenopausal Women. Journal of Cardiovascular Pharmacology 47:Supplement 2, pages S177-S186.
Crossref
Crossref
Carlo Selmi, Tin K. Mao, Carl L. Keen, Harold H. Schmitz & M. Eric Gershwin. (2006) The Anti-inflammatory Properties of Cocoa Flavanols. Journal of Cardiovascular Pharmacology 47:Supplement 2, pages S163-S171.
Crossref
Crossref
Mike Clifford & J Brown. 2005. Flavonoids. Flavonoids
319
370
.
Hideyuki Ito, Marie-Paule Gonthier, Claudine Manach, Christine Morand, Louise Mennen, Christian Rémésy & Augustin Scalbert. (2007) Polyphenol levels in human urine after intake of six different polyphenol-rich beverages. British Journal of Nutrition 94:4, pages 500-509.
Crossref
Crossref
Christian Heiss, Petra Kleinbongard, Andrè Dejam, Sandra Perré, Hagen Schroeter, Helmut Sies & Malte Kelm. (2005) Acute Consumption of Flavanol-Rich Cocoa and the Reversal of Endothelial Dysfunction in Smokers. Journal of the American College of Cardiology 46:7, pages 1276-1283.
Crossref
Crossref
Elena Roura, Cristina Andrés-Lacueva, Olga Jáuregui, Eva Badia, Ramon Estruch, Maria Izquierdo-Pulido & Rosa M. Lamuela-Raventós. (2005) Rapid Liquid Chromatography Tandem Mass Spectrometry Assay To Quantify Plasma (−)-Epicatechin Metabolites after Ingestion of a Standard Portion of Cocoa Beverage in Humans. Journal of Agricultural and Food Chemistry 53:16, pages 6190-6194.
Crossref
Crossref
R. M. Lamuela-RaventósA. I. Romero-Pérez, C. Andrés-Lacueva & A. Tornero. (2016) Review: Health Effects of Cocoa Flavonoids. Food Science and Technology International 11:3, pages 159-176.
Crossref
Crossref
Emma Ramiro, Àngels Franch, Cristina Castellote, Cristina Andrés-Lacueva, Maria Izquierdo-Pulido & Margarida Castell. (2007)
Effect of
Theobroma cacao
flavonoids on immune activation of a lymphoid cell line
. British Journal of Nutrition 93:6, pages 859-866.
Crossref
Crossref
R Ambra, R Canali, O Gulati & F Virgili. 2005. Nutrigenomics. Nutrigenomics
379
396
.
Tohru Kurosawa, Fumi Itoh, Aiko Nozaki, Yoshihisa Nakano, Shin-ichiro Katsuda, Naomi Osakabe, Hirokazu Tsubone, Kazuo Kondo & Hiroshige Itakura. (2005) Suppressive effects of cacao liquor polyphenols (CLP) on LDL oxidation and the development of atherosclerosis in Kurosawa and Kusanagi-hypercholesterolemic rabbits. Atherosclerosis 179:2, pages 237-246.
Crossref
Crossref
Naomi Osakabe. (2005) Important Role of Antioxidants in Oxidative Stress: Cacao Polyphenols and Atherosclerosis. Journal of Clinical Biochemistry and Nutrition 37:3, pages 67-72.
Crossref
Crossref
Helmut Sies, Tankred Schewe, Christian Heiss & Malte Kelm. (2005) Cocoa polyphenols and inflammatory mediators. The American Journal of Clinical Nutrition 81:1, pages 304S-312S.
Crossref
Crossref
Carl L Keen, Roberta R Holt, Patricia I Oteiza, César G Fraga & Harold H Schmitz. (2005) Cocoa antioxidants and cardiovascular health. The American Journal of Clinical Nutrition 81:1, pages 298S-303S.
Crossref
Crossref
Barry Halliwell, Joseph Rafter & Andrew Jenner. (2005) Health promotion by flavonoids, tocopherols, tocotrienols, and other phenols: direct or indirect effects? Antioxidant or not?. The American Journal of Clinical Nutrition 81:1, pages 268S-276S.
Crossref
Crossref
Claudine Manach, Gary Williamson, Christine Morand, Augustin Scalbert & Christian Rémésy. (2005) Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies. The American Journal of Clinical Nutrition 81:1, pages 230S-242S.
Crossref
Crossref
Angelita Gambuti, Daniela Strollo, Maurizio Ugliano, Lucia Lecce & Luigi Moio. (2004)
trans
-Resveratrol, Quercetin, (+)-Catechin, and (−)-Epicatechin Content in South Italian Monovarietal Wines: Relationship with Maceration Time and Marc Pressing during Winemaking
. Journal of Agricultural and Food Chemistry 52:18, pages 5747-5751.
Crossref
Crossref
Ingrid Wiswedel, Daniela Hirsch, Siegfried Kropf, Martin Gruening, Eberhard Pfister, Tankred Schewe & Helmut Sies. (2004) Flavanol-rich cocoa drink lowers plasma F 2 -isoprostane concentrations in humans. Free Radical Biology and Medicine 37:3, pages 411-421.
Crossref
Crossref
Paul A Kroon, Michael N Clifford, Alan Crozier, Andrea J Day, Jennifer L Donovan, Claudine Manach & Gary Williamson. (2004) How should we assess the effects of exposure to dietary polyphenols in vitro?. The American Journal of Clinical Nutrition 80:1, pages 15-21.
Crossref
Crossref
Claudine Manach, Augustin Scalbert, Christine Morand, Christian Rémésy & Liliana Jiménez. (2004) Polyphenols: food sources and bioavailability. The American Journal of Clinical Nutrition 79:5, pages 727-747.
Crossref
Crossref
Seigo Baba, Naomi Osakabe, Midori Natsume & Junji Terao. (2004) Orally administered rosmarinic acid is present as the conjugated and/or methylated forms in plasma, and is degraded and metabolized to conjugated forms of caffeic acid, ferulic acid and m-coumaric acid. Life Sciences 75:2, pages 165-178.
Crossref
Crossref
Thomas Walle. (2004) Absorption and metabolism of flavonoids. Free Radical Biology and Medicine 36:7, pages 829-837.
Crossref
Crossref
Seigo BABA & Junji TERAO. (2004) Role of Metabolism in Physiological Function of Polyphenol Catechins. Oleoscience 4:7, pages 271-277,270.
Crossref
Crossref
Kayoko Shimoi. (2004) . Environmental Mutagen Research 26:3, pages 241-246.
Crossref
Crossref
Naomi OsakabeSeigo BabaAkiko YasudaTamami Iwamoto, Masumi Kamiyama, Takahisa TokunagaKazuo Kondo. (2004) Dose-Response Study of Daily Cocoa Intake on the Oxidative Susceptibility of Low-Density Lipoprotein in Healthy Human Volunteers. Journal of Health Science 50:6, pages 679-684.
Crossref
Crossref
Naomi Osakabe, Megumi Yamagishi, Midori Natsume, Akiko Yasuda & Toshihiko Osawa. (2016) Ingestion of Proanthocyanidins Derived from Cacao Inhibits Diabetes-Induced Cataract Formation in Rats. Experimental Biology and Medicine 229:1, pages 33-39.
Crossref
Crossref
Jaya Bharathi Vaidyanathan & Thomas Walle. (2003) Cellular Uptake and Efflux of the Tea Flavonoid (-)Epicatechin-3-gallate in the Human Intestinal Cell Line Caco-2. Journal of Pharmacology and Experimental Therapeutics 307:2, pages 745-752.
Crossref
Crossref
Tomonori Unno, Kimiko Tamemoto, Fumihisa Yayabe & Takami Kakuda. (2003) Urinary Excretion of 5-(3‘,4‘-Dihydroxyphenyl)-γ-valerolactone, a Ring-Fission Metabolite of (−)-Epicatechin, in Rats and Its in Vitro Antioxidant Activity. Journal of Agricultural and Food Chemistry 51:23, pages 6893-6898.
Crossref
Crossref
Sharmila Basu-Modak, Matthew J Gordon, Laura H Dobson, Jeremy P.E Spencer, Catherine Rice-Evans & Rex M Tyrrell. (2003) Epicatechin and its methylated metabolite attenuate UVA-induced oxidative damage to human skin fibroblasts. Free Radical Biology and Medicine 35:8, pages 910-921.
Crossref
Crossref
Derek D Schramm, Malina Karim, Heather R Schrader, Roberta R Holt, Nadine J Kirkpatrick, John A Polagruto, Jodi L Ensunsa, Harold H Schmitz & Carl L Keen. (2003) Food effects on the absorption and pharmacokinetics of cocoa flavanols. Life Sciences 73:7, pages 857-869.
Crossref
Crossref
Karen J Murphy, Andriana K Chronopoulos, Indu Singh, Maureen A Francis, Helen Moriarty, Marilyn J Pike, Alan H Turner, Neil J Mann & Andrew J Sinclair. (2003) Dietary flavanols and procyanidin oligomers from cocoa (Theobroma cacao) inhibit platelet function,,. The American Journal of Clinical Nutrition 77:6, pages 1466-1473.
Crossref
Crossref
Santosh Khokhar & Richard.K. Owusu Apenten. (2003) Iron binding characteristics of phenolic compounds: some tentative structure–activity relations. Food Chemistry 81:1, pages 133-140.
Crossref
Crossref
Michal Ceregrzyn & Atsukazu Kuwahara. (2003) The effect of epigallocatechin gallate on intestinal motility in mice. Environmental Health and Preventive Medicine 8:2, pages 47-51.
Crossref
Crossref
Laurent Y Rios, Marie-Paule Gonthier, Christian Rémésy, Isabelle Mila, Catherine Lapierre, Sheryl A Lazarus, Gary Williamson & Augustin Scalbert. (2003) Chocolate intake increases urinary excretion of polyphenol-derived phenolic acids in healthy human subjects,,. The American Journal of Clinical Nutrition 77:4, pages 912-918.
Crossref
Crossref
Midori Natsume, Naomi Osakabe, Makoto Oyama, Motoko Sasaki, Seigo Baba, Yoshimasa Nakamura, Toshihiko Osawa & Junji Terao. (2003) Structures of (−)-epicatechin glucuronide identified from plasma and urine after oral ingestion of (−)-epicatechin: differences between human and rat. Free Radical Biology and Medicine 34:7, pages 840-849.
Crossref
Crossref
Francene M Steinberg, Monica M Bearden & Carl L Keen. (2003) Cocoa and chocolate flavonoids: Implications for cardiovascular health. Journal of the American Dietetic Association 103:2, pages 215-223.
Crossref
Crossref
Megumi Yamagishi, Midori Natsume, Naomi Osakabe, Kazushi Okazaki, Fumio Furukawa, Takayoshi Imazawa, Akiyoshi Nishikawa & Masao Hirose. (2003) Chemoprevention of lung carcinogenesis by cacao liquor proanthocyanidins in a male rat multi-organ carcinogenesis model. Cancer Letters 191:1, pages 49-57.
Crossref
Crossref
Edzard Schwedhelm, Renke Maas, Raphael Troost & Rainer H B??ger. (2003) Clinical Pharmacokinetics of Antioxidants and Their Impact on Systemic Oxidative Stress. Clinical Pharmacokinetics 42:5, pages 437-459.
Crossref
Crossref
T.K. Mao, J. Van De Water, C.L. Keen, H.H. Schmitz & M.E. Gershwin. (2016)
Cocoa Flavonols and Procyanidins Promote Transforming Growth Factor-β
1
Homeostasis in Peripheral Blood Mononuclear Cells
1
. Experimental Biology and Medicine 228:1, pages 93-99.
Crossref
Crossref
Qin Yan Zhu, John F. Hammerstone, Sheryl A. Lazarus, Harold H. Schmitz & Carl L. Keen. (2002) Stabilizing Effect of Ascorbic Acid on Flavan-3-ols and Dimeric Procyanidins from Cocoa. Journal of Agricultural and Food Chemistry 51:3, pages 828-833.
Crossref
Crossref
Piergiorgio Pietta, Markus Minoggio & Lorenzo Bramati. 2003. Bioactive Natural Products (Part I). Bioactive Natural Products (Part I)
257
312
.
Carl L. Keen, Roberta R. Holt, Fernando Carrasquedo, M. Eric Gershwin, Tin K. Mao & Harold H. Schmitz. 2003. Frontiers in Cardiovascular Health. Frontiers in Cardiovascular Health
209
226
.
Surekha Mathur, Scott M. Grundy, Sridevi Devaraj & Ishwarlal Jialal. (2002) Cocoa Products Decrease Low Density Lipoprotein Oxidative Susceptibility but Do Not Affect Biomarkers of Inflammation in Humans. The Journal of Nutrition 132:12, pages 3663-3667.
Crossref
Crossref
Megumi Yamagishi, Midori Natsume, Naomi Osakabe, Hideaki Nakamura, Fumio Furukawa, Takayoshi Imazawa, Akiyoshi Nishikawa & Masao Hirose. (2002) Effects of cacao liquor proanthocyanidins on PhIP-induced mutagenesis in vitro, and in vivo mammary and pancreatic tumorigenesis in female Sprague–Dawley rats. Cancer Letters 185:2, pages 123-130.
Crossref
Crossref
Roberta R Holt, Sheryl A Lazarus, M Cameron Sullards, Qin Yan Zhu, Derek D Schramm, John F Hammerstone, Cesar G Fraga, Harold H Schmitz & Carl L Keen. (2002) Procyanidin dimer B2 [epicatechin-(4β-8)-epicatechin] in human plasma after the consumption of a flavanol-rich cocoa,,. The American Journal of Clinical Nutrition 76:4, pages 798-804.
Crossref
Crossref
Javier I Ottaviani, Fernando Carrasquedo, Carl L Keen, Sheryl A Lazarus, Harold H Schmitz & Cesar G. Fraga. (2002) Influence of flavan-3-ols and procyanidins on UVC-mediated formation of 8-oxo-7,8-dihydro-2′-deoxyguanosine in isolated DNA. Archives of Biochemistry and Biophysics 406:2, pages 203-208.
Crossref
Crossref
Jaya Bharathi Vaidyanathan & Thomas Walle. (2002) Glucuronidation and Sulfation of the Tea Flavonoid (−)-Epicatechin by the Human and Rat Enzymes. Drug Metabolism and Disposition 30:8, pages 897-903.
Crossref
Crossref
Tankred Schewe, Helmut Sies & Hartmut Kühn. (2002) Flavonoids of Cocoa Inhibit Recombinant Human 5-Lipoxygenase. The Journal of Nutrition 132:7, pages 1825-1829.
Crossref
Crossref
Seigo Baba, Naomi Osakabe, Midori Natsume & Junji Terao. (2002) Absorption and urinary excretion of procyanidin B2 [epicatechin-(4β-8)-epicatechin] in rats. Free Radical Biology and Medicine 33:1, pages 142-148.
Crossref
Crossref
Carl L. Keen, Roberta R. Holt, John A. Polagruto, Janice F. Wang & Harold H. Schmitz. (2002) Cocoa flavanols and cardiovascular health. Phytochemistry Reviews 1:2, pages 231-240.
Crossref
Crossref
Debra A Pearson, Teresa G Paglieroni, Dietrich Rein, Ted Wun, Derek D Schramm, Janice F Wang, Roberta R Holt, Robert Gosselin, Harold H Schmitz & Carl L Keen. (2002) The effects of flavanol-rich cocoa and aspirin on ex vivo platelet function. Thrombosis Research 106:4-5, pages 191-197.
Crossref
Crossref
Jennifer L. Donovan, Adam Lee, Claudine Manach, Laurent Rios, Christine Morand, Augustin Scalbert & Christian Rémésy. (2007)
Procyanidins are not bioavailable in rats fed a single meal containing a grapeseed extract or the procyanidin dimer B
3
. British Journal of Nutrition 87:4, pages 299-306.
Crossref
Crossref
Penny M. Kris-Etherton & Carl L. Keen. (2002) Evidence that the antioxidant flavonoids in tea and cocoa are beneficial for cardiovascular health. Current Opinion in Lipidology 13:1, pages 41-49.
Crossref
Crossref
K.A. Youdim, J.P.E. Spencer, H. Schroeter & C. Rice-Evans. (2002) Dietary Flavonoids as Potential Neuroprotectants. Biological Chemistry 383:3-4.
Crossref
Crossref
Naomi Osakabe, Akiko Yasuda, Midori Natsume, Toshio Takizawa, Junji Terao & Kazuo Kondo. (2016) Catechins and Their Oligomers Linked by C4 → C8 Bonds are Major Cacao Polyphenols and Protect Low-Density Lipoprotein from Oxidation In Vitro. Experimental Biology and Medicine 227:1, pages 51-56.
Crossref
Crossref
Seigo Baba, Naomi Osakabe, Midori Natsume, Yuko Muto, Toshio Takizawa & Junji Terao. (2001) Absorption and Urinary Excretion of (−)-Epicatechin after Administration of Different Levels of Cocoa Powder or (−)-Epicatechin in Rats. Journal of Agricultural and Food Chemistry 49:12, pages 6050-6056.
Crossref
Crossref
Seigo Baba, Naomi Osakabe, Midori Natsume, Yuko Muto, Toshio Takizawa & Junji Terao. (2001) In Vivo Comparison of the Bioavailability of (+)-Catechin, (−)-Epicatechin and Their Mixture in Orally Administered Rats. The Journal of Nutrition 131:11, pages 2885-2891.
Crossref
Crossref
Jeremy P.E Spencer, Hagen Schroeter, Andrew J Crossthwaithe, Gunter Kuhnle, Robert J Williams & Catherine Rice-Evans. (2001) Contrasting influences of glucuronidation and O -methylation of epicatechin on hydrogen peroxide-induced cell death in neurons and fibroblasts. Free Radical Biology and Medicine 31:9, pages 1139-1146.
Crossref
Crossref
Jeremy P.E. Spencer, Hagen Schroeter, Baskar Shenoy, S.Kaila S. Srai, Edward S. Debnam & Catherine Rice-Evans. (2001) Epicatechin Is the Primary Bioavailable Form of the Procyanidin Dimers B2 and B5 after Transfer across the Small Intestine. Biochemical and Biophysical Research Communications 285:3, pages 588-593.
Crossref
Crossref
Tankred Schewe, Christian Sadik, Lars-Oliver Klotz, Tanihiro Yoshimoto, Hartmut Kühn & Helmut Sies. (2001) Polyphenols of Cocoa: Inhibition of Mammalian 15-Lipoxygenase. Biological Chemistry 382:12.
Crossref
Crossref