Citations (58)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (1)
Gabriela Elisa Hirsch & Thiago Gomes Heck. (2022) Inflammation, oxidative stress and altered heat shock response in type 2 diabetes: the basis for new pharmacological and non-pharmacological interventions. Archives of Physiology and Biochemistry 128:2, pages 411-425.
Read now
Read now
Articles from other publishers (57)
Daisuke Oikawa, Min Gi, Hidetaka Kosako, Kouhei Shimizu, Hirotaka Takahashi, Masayuki Shiota, Shuhei Hosomi, Keidai Komakura, Hideki Wanibuchi, Daisuke Tsuruta, Tatsuya Sawasaki & Fuminori Tokunaga. (2022) OTUD1 deubiquitinase regulates NF-κB- and KEAP1-mediated inflammatory responses and reactive oxygen species-associated cell death pathways. Cell Death & Disease 13:8.
Crossref
Crossref
Shinae HwangJong-Keun Kim. (2022) N-Acetylcysteine Induces Apoptotic, Oxidative and Excitotoxic Neuronal Death in Mouse Cortical Cultures. Chonnam Medical Journal 58:1, pages 18.
Crossref
Crossref
Dorothea D Jenkins, Hunter G Moss, Truman R Brown, Milad Yazdani, Sudhin Thayyil, Paolo Montaldo, Maximo Vento, Julia Kuligowski, Carol Wagner, Bruce W Hollis & Donald B Wiest. (2021) NAC and Vitamin D Improve CNS and Plasma Oxidative Stress in Neonatal HIE and Are Associated with Favorable Long-Term Outcomes. Antioxidants 10:9, pages 1344.
Crossref
Crossref
Orna Ernst, Jing SunBin LinBalaji Banoth, Michael G. DorringtonJonathan Liang, Benjamin Schwarz, Kaitlin A. Stromberg, Samuel KatzSharat J. Vayttaden, Clinton J. Bradfield, Nadia Slepushkina, Christopher M. RiceEugen Buehler, Jaspal S. Khillan, Daniel W. McVicarCatharine M. BosioClare E. BryantFayyaz S. SutterwalaScott E. MartinMadhu Lal-Nag & Iain D. C. Fraser. (2021) A genome-wide screen uncovers multiple roles for mitochondrial nucleoside diphosphate kinase D in inflammasome activation. Science Signaling 14:694.
Crossref
Crossref
Helmut Schweikl, Margaritha Birke, Marialucia Gallorini, Christine Petzel, Carola Bolay, Claudia Waha, Karl-Anton Hiller & Wolfgang Buchalla. (2020) HEMA-induced oxidative stress inhibits NF-κB nuclear translocation and TNF release from LTA- and LPS-stimulated immunocompetent cells. Dental Materials.
Crossref
Crossref
Huawei Niu, Jun Tang, Xiaofei Zhu, Zipeng Li, Yongru Zhang, Yong Ye & Yufen Zhao. (2020) A three-channel fluorescent probe to image mitochondrial stress. Chemical Communications 56:56, pages 7710-7713.
Crossref
Crossref
Shirinsadat Badri, Rasool Soltani, Mina Sayadi, Farzin Khorvash, Mohsen Meidani & Shahram Taheri. (2020) Effect of N-acetylcysteine against Vancomycin-Induced Nephrotoxicity: A Randomized Controlled Clinical Trial. Archives of Iranian Medicine 23:6, pages 397-402.
Crossref
Crossref
Kamila Prymas, Anna Świątkowska, Gabriela Traczyk, Ewelina Ziemlińska, Anna Dziewulska, Anna Ciesielska & Katarzyna Kwiatkowska. (2020) Sphingomyelin synthase activity affects TRIF-dependent signaling of Toll-like receptor 4 in cells stimulated with lipopolysaccharide. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1865:2, pages 158549.
Crossref
Crossref
Patrícia Santos, Ana P. Herrmann, Elaine Elisabetsky & Angelo Piato. (2019) Anxiolytic properties of compounds that counteract oxidative stress, neuroinflammation, and glutamatergic dysfunction: a review. Brazilian Journal of Psychiatry 41:2, pages 168-178.
Crossref
Crossref
Sami A. Gabr, Nada S. Gabr & Wael M. Elsaed. (2019) Aqueous Green Tea Extract and Prediction of Fibrosis in Lipopolysaccharide Intoxicated Rats. International Journal of Pharmacology 15:3, pages 403-417.
Crossref
Crossref
Joy E. Tomlinson, Emilija Žygelytė, Jennifer K. Grenier, Michael G. Edwards & Jonathan Cheetham. (2018) Temporal changes in macrophage phenotype after peripheral nerve injury. Journal of Neuroinflammation 15:1.
Crossref
Crossref
Jason Chertoff. (2017)
N
-Acetylcysteine’s Role in Sepsis and Potential Benefit in Patients With Microcirculatory Derangements
. Journal of Intensive Care Medicine 33:2, pages 87-96.
Crossref
Crossref
Mohamed A. Zayed, Xiachao Wei, Kyoung‐mi Park, Larisa Belaygorod, Uzma Naim, Joseph Harvey, Li Yin, Kendall Blumer & Clay F. Semenkovich. (2017)
N
‐acetylcysteine accelerates amputation stump healing in the setting of diabetes
. The FASEB Journal 31:6, pages 2686-2695.
Crossref
Crossref
Nádia J. Almeida Cardelli, M. Elisa Lopes-Pires, Pedro H.L. Bonfitto, Heloisa H. Ferreira, Edson Antunes & Sisi Marcondes. (2017) Cross-talking between lymphocytes and platelets and its regulation by nitric oxide and peroxynitrite in physiological condition and endotoxemia. Life Sciences 172, pages 2-7.
Crossref
Crossref
Flavia Lambertucci, Omar Motiño, Silvina Villar, Juan Pablo Rigalli, María de Luján Alvarez, Viviana A Catania, Paloma Martín-Sanz, Cristina Ester Carnovale, Ariel Darío Quiroga, Daniel Eleazar Francés & María Teresa Ronco. (2017) Benznidazole, the trypanocidal drug used for Chagas disease, induces hepatic NRF2 activation and attenuates the inflammatory response in a murine model of sepsis. Toxicology and Applied Pharmacology 315, pages 12-22.
Crossref
Crossref
Xingju Nie, Danielle W. Lowe, Laura Grace Rollins, Jessica Bentzley, Jamie L. Fraser, Renee Martin, Inderjit Singh & Dorothea Jenkins. (2016) Sex-specific effects of N-acetylcysteine in neonatal rats treated with hypothermia after severe hypoxia-ischemia. Neuroscience Research 108, pages 24-33.
Crossref
Crossref
E Taslidere, N Vardi, M Esrefoglu, B Ates, C Taskapan & S Yologlu. (2015)
The effects of pentoxifylline and caffeic acid phenethyl ester in the treatment of
d
-galactosamine-induced acute hepatitis in rats
. Human & Experimental Toxicology 35:4, pages 353-365.
Crossref
Crossref
Deepmala, John Slattery, Nihit Kumar, Leanna Delhey, Michael Berk, Olivia Dean, Charles Spielholz & Richard Frye. (2015) Clinical trials of N-acetylcysteine in psychiatry and neurology: A systematic review. Neuroscience & Biobehavioral Reviews 55, pages 294-321.
Crossref
Crossref
Dharmendra Kumar, Abhai Kumar, Smita Singh & Ragini Tilak. (2015) Candidemia-induced pediatric sepsis and its association with free radicals, nitric oxide, and cytokine level in host. Journal of Critical Care 30:2, pages 296-303.
Crossref
Crossref
Victor M. Victor. 2014. Systems Biology of Free Radicals and Antioxidants. Systems Biology of Free Radicals and Antioxidants
1305
1323
.
Fernanda S. Rodrigues, Mauren A. Souza, Danieli V. Magni, Ana Paula O. Ferreira, Bibiana C. Mota, Andreia M. Cardoso, Mariana Paim, Léder L. Xavier, Juliano Ferreira, Maria Rosa C. Schetinger, Jaderson C. Da Costa, Luiz Fernando F. Royes & Michele R. Fighera. (2013) N-Acetylcysteine Prevents Spatial Memory Impairment Induced by Chronic Early Postnatal Glutaric Acid and Lipopolysaccharide in Rat Pups. PLoS ONE 8:10, pages e78332.
Crossref
Crossref
Kanyi Pu, Adam J. Shuhendler & Jianghong Rao. (2013) Semiconducting Polymer Nanoprobe for In Vivo Imaging of Reactive Oxygen and Nitrogen Species. Angewandte Chemie International Edition 52:39, pages 10325-10329.
Crossref
Crossref
Kanyi Pu, Adam J. Shuhendler & Jianghong Rao. (2013) Semiconducting Polymer Nanoprobe for In Vivo Imaging of Reactive Oxygen and Nitrogen Species. Angewandte Chemie 125:39, pages 10515-10519.
Crossref
Crossref
Weidong Xie, Mengnan Li, Naihan Xu, Qing Lv, Nunu Huang, Jie He & Yaou Zhang. (2013) miR-181a Regulates Inflammation Responses in Monocytes and Macrophages. PLoS ONE 8:3, pages e58639.
Crossref
Crossref
Genevieve C. Van de Bittner, Carolyn R. Bertozzi & Christopher J. Chang. (2013)
Strategy for Dual-Analyte Luciferin Imaging:
In Vivo
Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
. Journal of the American Chemical Society 135:5, pages 1783-1795.
Crossref
Crossref
Karla Maria Pereira Pires, Manuella Lanzetti, Carlos Romualdo Rueff-Barroso, Paulo Castro, Agessandro Abrahão, Vera Lúcia Gonçalves Koatz, Samuel Santos Valença & Luís Cristóvão Porto. (2012) Oxidative damage in alveolar macrophages exposed to cigarette smoke extract and participation of nitric oxide in redox balance. Toxicology in Vitro 26:6, pages 791-798.
Crossref
Crossref
Ana Paula Oliveira Ferreira, Juliana Saibt Martins Pasin, André Luis Lopes Saraiva, Viviane Ratzlaff, Mateus Fortes Rossato, Rosália Andrighetto, Maribel Antonello Rubin, Juliano Ferreira & Carlos Fernando Mello. (2011) N-Acetylcysteine prevents baker’s-yeast-induced inflammation and fever. Inflammation Research 61:2, pages 103-112.
Crossref
Crossref
André Luis Casarin, Maria Elisa Lopes-Pires, Rafael Prada Morganti, Edson Antunes & Sisi Marcondes. (2011) Reactive oxygen and nitrogen species modulate the ex-vivo effects of LPS on platelet adhesion to fibrinogen. Life Sciences 89:21-22, pages 773-778.
Crossref
Crossref
Hwa Sung Chae, Hyun-Jung Park, Hyo Rin Hwang, Arang Kwon, Won-Hee Lim, Won Jin Yi, Dong-Hun Han, Young Ho Kim & Jeong-Hwa Baek. (2011) The effect of antioxidants on the production of pro-inflammatory cytokines and orthodontic tooth movement. Molecules and Cells 32:2, pages 189-196.
Crossref
Crossref
L. Arranz, J. H. Caamano, J. M. Lord & M. De la Fuente. (2010) Preserved Immune Functions and Controlled Leukocyte Oxidative Stress in Naturally Long-lived Mice: Possible Role of Nuclear Factor Kappa B. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 65A:9, pages 941-950.
Crossref
Crossref
Yalin Emre & Tobias Nübel. (2010) Uncoupling protein UCP2: When mitochondrial activity meets immunity. FEBS Letters 584:8, pages 1437-1442.
Crossref
Crossref
Paolo Puddu, Giovanni M Puddu, Eleonora Cravero, Susanna De Pascalis & Antonio Muscari. (2009) The emerging role of cardiovascular risk factor-induced mitochondrial dysfunction in atherogenesis. Journal of Biomedical Science 16:1.
Crossref
Crossref
Wenbo Zhang, Babak Baban, Modesto Rojas, Sohrab Tofigh, Suvika K. Virmani, Chintan Patel, M. Ali Behzadian, Maritza J. Romero, Robert W. Caldwell & Ruth B. Caldwell. (2009) Arginase Activity Mediates Retinal Inflammation in Endotoxin-Induced Uveitis. The American Journal of Pathology 175:2, pages 891-902.
Crossref
Crossref
Atish Prakash & Anil Kumar. (2009)
Effect of
N
-Acetyl Cysteine against Aluminium-induced Cognitive Dysfunction and Oxidative Damage in Rats
. Basic & Clinical Pharmacology & Toxicology 105:2, pages 98-104.
Crossref
Crossref
Kwanjit Sompamit, Upa Kukongviriyapan, Saowanee Nakmareong, Patchareewan Pannangpetch & Veerapol Kukongviriyapan. (2009) Curcumin improves vascular function and alleviates oxidative stress in non-lethal lipopolysaccharide-induced endotoxaemia in mice. European Journal of Pharmacology 616:1-3, pages 192-199.
Crossref
Crossref
Mi-La Cho, Young-Mee Moon, Yu-Jung Heo, Yun-Ju Woo, Ji-Hyeon Ju, Kyung-Su Park, Sung-Il Kim, Sung-Hwan Park, Ho-Youn Kim & Jun-Ki Min. (2009) NF-κB inhibition leads to increased synthesis and secretion of MIF in human CD4+ T cells. Immunology Letters 123:1, pages 21-30.
Crossref
Crossref
Wei-Jian Zhang, Hao Wei & Balz Frei. (2009) Genetic deficiency of NADPH oxidase does not diminish, but rather enhances, LPS-induced acute inflammatory responses in vivo. Free Radical Biology and Medicine 46:6, pages 791-798.
Crossref
Crossref
Xiaojie Meng, Ko-ichi Kawahara, Yuko Nawa, Naoki Miura, Binita Shrestha, Salunya Tancharoen, Hisayo Sameshima, Teruto Hashiguchi & Ikuro Maruyama. (2009) 1,5-Anhydro-d-fructose attenuates lipopolysaccharide-induced cytokine release via suppression of NF-κB p65 phosphorylation. Biochemical and Biophysical Research Communications 380:2, pages 343-348.
Crossref
Crossref
Manjeet K Paintlia, Ajaib S Paintlia, Avtar K Singh & Inderjit Singh. (2008) Attenuation of Lipopolysaccharide-Induced Inflammatory Response and Phospholipids Metabolism at the Feto-Maternal Interface by N-Acetyl Cysteine. Pediatric Research 64:4, pages 334-339.
Crossref
Crossref
Feng Zhang, Xinying Wang, Weiya Wang, Ning Li & Jieshou Li. (2008) Glutamine Reduces TNF-α by Enhancing Glutathione Synthesis in Lipopolysaccharide-Stimulated Alveolar Epithelial Cells of Rats. Inflammation 31:5, pages 344-350.
Crossref
Crossref
J S Thompson, R Asmis, Y Chu, J Glass, B Nelson & S A Brown. (2008) Amifostine prior to lethal irradiation prevents allogeneic bone marrow engraftment in mice. Bone Marrow Transplantation 41:11, pages 927-934.
Crossref
Crossref
Manjeet K. Paintlia, Ajaib S. Paintlia, Mushfiquddin Khan, Inderjit Singh & Avtar K. Singh. (2008) Modulation of peroxisome proliferator-activated receptor-α activity by N-acetyl cysteine attenuates inhibition of oligodendrocyte development in lipopolysaccharide stimulated mixed glial cultures. Journal of Neurochemistry 105:3, pages 956-970.
Crossref
Crossref
Manjeet K. Paintlia, Ajaib S. Paintlia, Miguel A. Contreras, Inderjit Singh & Avtar K. Singh. (2008) Lipopolysaccharide-induced peroxisomal dysfunction exacerbates cerebral white matter injury: Attenuation by N-acetyl cysteine. Experimental Neurology 210:2, pages 560-576.
Crossref
Crossref
Do Young Kim, Ji-Hae Jun, Hye-Lim Lee, Kyung Mi Woo, Hyun-Mo Ryoo, Gwan-Shik Kim, Jeong-Hwa Baek & Soo-Boo Han. (2007) N-acetyicysteine prevents lps-lnduced pro-inflammatory cytokines and mmp2 production in gingival fibroblasts. Archives of Pharmacal Research 30:10, pages 1283-1292.
Crossref
Crossref
Johnny Amer, Lola Weiss, Shoshana Reich, Michael Y. Shapira, Shimon Slavin & Eitan Fibach. (2007) The oxidative status of blood cells in a murine model of graft-versus-host disease. Annals of Hematology 86:10, pages 753-758.
Crossref
Crossref
Chul-Su Yang, Dong-Seok Lee, Chang-Hwa Song, Se-Jin An, Shengjin Li, Jin-Man Kim, Cuk Seong Kim, Dae Goon Yoo, Byeong Hwa Jeon, Hee-Young Yang, Tae-Hoon Lee, Zee-Won Lee, Jamel El-Benna, Dae-Yeul Yu & Eun-Kyeong Jo. (2007) Roles of peroxiredoxin II in the regulation of proinflammatory responses to LPS and protection against endotoxin-induced lethal shock. The Journal of Experimental Medicine 204:3, pages 583-594.
Crossref
Crossref
Lorena Arranz, Cesáreo Fernández, Antonio Rodríguez, José Manuel Ribera & Mónica de la Fuente. (2007) Cambios con el envejecimiento en los valores de glutatión de células inmunitarias y plasma. Efecto de la administración de N-acetilcisteína. Revista Española de Geriatría y Gerontología 42:2, pages 96-102.
Crossref
Crossref
Jennyfer Bultinck, Patrick Sips, Luc Vakaet, Peter Brouckaert, Anje Cauwels, Jennyfer Bultinck, Patrick Sips, Luc Vakaet, Peter Brouckaert & Anje Cauwels. (2006) Systemic NO production during (septic) shock depends on parenchymal and not on hematopoietic cells: in vivo iNOS expression pattern in (septic) shock. The FASEB Journal 20:13, pages 2363-2365.
Crossref
Crossref
Joo-Young Im, Doyeun Kim, Sang-Gi Paik & Pyung-Lim Han. (2006) Cyclooxygenase-2-dependent neuronal death proceeds via superoxide anion generation. Free Radical Biology and Medicine 41:6, pages 960-972.
Crossref
Crossref
Shinya Ohashi, Akiyoshi Nishio, Hajime Nakamura, Masahiro Kido, Satoru Ueno, Norimitsu Uza, Satoko Inoue, Hiroshi Kitamura, Keiichi Kiriya, Masanori Asada, Hiroyuki Tamaki, Minoru Matsuura, Kimio Kawasaki, Toshiro Fukui, Norihiko Watanabe, Hiroshi Nakase, Junji Yodoi, Kazuichi Okazaki & Tsutomu Chiba. (2006) Protective roles of redox-active protein thioredoxin-1 for severe acute pancreatitis. American Journal of Physiology-Gastrointestinal and Liver Physiology 290:4, pages G772-G781.
Crossref
Crossref
Katarzyna Winiarska, Tomasz Fraczyk, Dominika Malinska, Jakub Drozak & Jadwiga Bryla. (2006) Melatonin attenuates diabetes-induced oxidative stress in rabbits. Journal of Pineal Research 40:2, pages 168-176.
Crossref
Crossref
Cristiane Ritter, Aline Andrea da Cunha, Isabel Cristina Echer, Michael Andrades, Adalisa Reinke, Newton Lucchiari, João Rocha, Emílio Luiz Streck, Sérgio Menna-Barreto, José Cláudio F. Moreira & Felipe Dal-Pizzol. (2006) Effects of N-acetylcysteine plus deferoxamine in lipopolysaccharide-induced acute lung injury in the rat*. Critical Care Medicine 34:2, pages 471-477.
Crossref
Crossref
De-Xiang Xu, Yuan-Hua Chen, Hua Wang, Lei Zhao, Jian-Ping Wang & Wei Wei. (2005) Effect of N-Acetylcysteine on Lipopolysaccharide-Induced Intra-uterine Fetal Death and Intra-uterine Growth Retardation in Mice. Toxicological Sciences 88:2, pages 525-533.
Crossref
Crossref
Lo-Ti Tsao, Pei-Shan Tsai, Ruey-Hseng Lin, Li-Jiau Huang, Sheng-Chu Kuo & Jih-Pyang Wang. (2005) Inhibition of lipopolysaccharide-induced expression of inducible nitric oxide synthase by phenolic (3E)-4-(2-hydroxyphenyl)but-3-en-2-one in RAW 264.7 macrophages. Biochemical Pharmacology 70:4, pages 618-626.
Crossref
Crossref
Noelia Guayerbas, Marta Puerto, Carmen Alvarado & Mónica De la Fuente. (2005) Effect of diet supplementation with N-acetylcysteine on leucocyte functions in prematurely aging mice. Journal of Applied Biomedicine 3:4, pages 199-205.
Crossref
Crossref
De-Xiang Xu, Wei Wei, Mei-Fang Sun, Cheng-Yi Wu, Jian-Ping Wang, Ling-Zhen Wei & Cheng-fan Zhou. (2004) Kupffer cells and reactive oxygen species partially mediate lipopolysaccharide-induced downregulation of nuclear receptor pregnane x receptor and its target gene CYP3a in mouse liver. Free Radical Biology and Medicine 37:1, pages 10-22.
Crossref
Crossref
Victor M. Victor, Milagros Rocha & Monica De la Fuente. (2004) Immune cells: free radicals and antioxidants in sepsis. International Immunopharmacology 4:3, pages 327-347.
Crossref
Crossref