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Original Article

In Vitro Antioxidative Activity of (−)-Epicatechin Glucuronide Metabolites Present in Human and Rat Plasma

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Pages 1341-1348 | Received 05 Jul 2004, Published online: 07 Jul 2009

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Naomi Osakabe. (2005) Important Role of Antioxidants in Oxidative Stress: Cacao Polyphenols and Atherosclerosis. Journal of Clinical Biochemistry and Nutrition 37:3, pages 67-72.
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