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Free Radical Research Volume 40, 2006 - Issue 9
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Original

Differential regulation of hepatic cytochrome P450 monooxygenases in streptozotocin-induced diabetic rats

Ram K. Sindhu UCLA School of Medicine, Charles R. Drew University of Medicine and Science, Division of Nephrology and Hypertension, Department of Internal Medicine, Los Angeles, CA90059, USACorrespondence[email protected]
,
Ja-Ryung Koo University of California, Department of Medicine, Irvine, CA, 92697, USA
,
Kunal K. Sindhu University of California, Berkeley, CA94720, USA
,
Ashkan Ehdaie UCLA School of Medicine, Charles R. Drew University of Medicine and Science, Division of Nephrology and Hypertension, Department of Internal Medicine, Los Angeles, CA90059, USA
,
Farbod Farmand University of California, Department of Medicine, Irvine, CA, 92697, USA
&
Christian K. Roberts University of California at Los Angeles, Department of Physiological Science, Los Angeles, CA90095, USA
Pages 921-928 | Received 10 Jan 2006, Published online: 07 Jul 2009

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Feng Chen, De-Yi Li, Bo Zhang, Jie-Yu Sun, Fang Sun, Xing Ji, Jin-Chun Qiu, Robert B. Parker, S. Casey Laizure & Jing Xu. (2018) Alterations of drug-metabolizing enzymes and transporters under diabetic conditions: what is the potential clinical significance?. Drug Metabolism Reviews 50:3, pages 369-397.
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Articles from other publishers (31)

Karima Begriche, Clémence Penhoat, Pénélope Bernabeu-Gentey, Julie Massart & Bernard Fromenty. (2023) Acetaminophen-Induced Hepatotoxicity in Obesity and Nonalcoholic Fatty Liver Disease: A Critical Review. Livers 3:1, pages 33-53.
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Asieh Karimani. (2022) Evaluating Cytochrome P-2E1 Induction in Diabetic Rats and Rabbits. Journal of Medical Sciences 22:4, pages 158-164.
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Noha SAYED, Ikue MURATA, Osama ABDALLA, Omnia KILANY, Amina DESSOUKI & Kazuaki SASAKI. (2021) Effects of dapagliflozin in combination with insulin on cytochrome P450 activities in a diabetes type 1 rat model. Journal of Veterinary Medical Science 83:10, pages 1597-1603.
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Julie Massart, Karima Begriche & Bernard Fromenty. (2021) Cytochrome P450 2E1 should not be neglected for acetaminophen-induced liver injury in metabolic diseases with altered insulin levels or glucose homeostasis. Clinics and Research in Hepatology and Gastroenterology 45:1, pages 101470.
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Kazuma Kondo, Naohito YamadaYusuke SuzukiTatsuji HashimotoKaoru ToyodaTadakazu TakahashiAkio KobayashiShoichiro SugaiKouichi Yoshinari. (2020) Enhancement of acetaminophen-induced chronic hepatotoxicity in spontaneously diabetic torii (SDT) rats. The Journal of Toxicological Sciences 45:5, pages 245-260.
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Dale A. Lauver, Dawn S. Kuszynski, Barbara D. Christian, Matthew P. Bernard, James P. Teuber, Bruce E. Markham, Yuqing E. Chen & Haoming Zhang. (2019) DT‐678 inhibits platelet activation with lower tendency for bleeding compared to existing P2Y 12 antagonists . Pharmacology Research & Perspectives 7:4.
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Ana Leonor Pardo Campos Godoy, Natália Valadares de Moraes, Jhohann Richard de Lima Benzi & Vera Lucia Lanchote. (2019) Changes in tramadol enantioselective pharmacokinetics and metabolism in rats with experimental diabetes treated or not with insulin. European Journal of Pharmaceutical Sciences 128, pages 97-102.
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Kuo-Chen Wu & Chun-Jung Lin. (2019) The regulation of drug-metabolizing enzymes and membrane transporters by inflammation: Evidences in inflammatory diseases and age-related disorders. Journal of Food and Drug Analysis 27:1, pages 48-59.
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Junjun Wang, Ting Zhai & Yong Chen. (2018) Effects of Honokiol on CYP450 Activity and Transporter mRNA Expression in Type 2 Diabetic Rats. International Journal of Molecular Sciences 19:3, pages 815.
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Wen-Chang Chang, Da-Wei Huang, Jou-An Chen, Yu-Fang Chang, James Swi-Bea Wu & Szu-Chuan Shen. (2018) Protective effect of Ruellia tuberosa  L. extracts against abnormal expression of hepatic detoxification enzymes in diabetic rats . RSC Advances 8:38, pages 21596-21605.
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D. Martínez, A. Castro, P. M. Merino, P. López, M. C. Lardone, G. Iñiguez, F. Cassorla & E. Codner. (2016) Oestrogen activity of the serum in adolescents with Type 1 diabetes. Diabetic Medicine 33:10, pages 1366-1373.
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Xiao-yan Zeng, Shu Dong, Nan-nan He, Chun-jie Jiang, Yue Dai & Yu-feng Xia. (2015) Comparative pharmacokinetics of arctigenin in normal and type 2 diabetic rats after oral and intravenous administration. Fitoterapia 105, pages 119-126.
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David J. Waxman & Thomas K. H. Chang. 2015. Cytochrome P450. Cytochrome P450 813 850 .
Jing Xiong, Wei Shang, Lili Wu, Ruini Chen, Wei Liu, Rui Ning, Gang Hu & Jian Yang. (2014) Glucose dominates the regulation of carboxylesterases induced by lipopolysaccharide or interleukin-6 in primary mouse hepatocytes. Life Sciences 112:1-2, pages 41-48.
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A. Vornoli, L. Pozzo, C.M. Della Croce, P.G. Gervasi & V. Longo. (2014) Drug metabolism enzymes in a steatotic model of rat treated with a high fat diet and a low dose of streptozotocin. Food and Chemical Toxicology 70, pages 54-60.
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Suzy M. Salama, Mahmood A. Abdulla, Ahmed S. AlRashdi & A. Hamid A. Hadi. (2013) Mechanism of Hepatoprotective Effect of Boesenbergia rotunda in Thioacetamide-Induced Liver Damage in Rats . Evidence-Based Complementary and Alternative Medicine 2013, pages 1-13.
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Aparajita Dey. 2013. Cytochrome P450 2E1: Its Role in Disease and Drug Metabolism. Cytochrome P450 2E1: Its Role in Disease and Drug Metabolism 1 104 .
Huihui Liu, Bin Wu, Guoyu Pan, Lei He, Zhixiong Li, Mingsong Fan, Longhai Jian, Mingcang Chen, Ke Wang & Chenggang Huang. (2012) Metabolism and Pharmacokinetics of Mangiferin in Conventional Rats, Pseudo-Germ-Free Rats, and Streptozotocin-Induced Diabetic Rats. Drug Metabolism and Disposition 40:11, pages 2109-2118.
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Haiyan Liu, Li Liu, Jia Li, Dan Mei, Ru Duan, Nan Hu, Haifang Guo, Zeyu Zhong & Xiaodong Liu. (2012) Combined Contributions of Impaired Hepatic CYP2C11 and Intestinal Breast Cancer Resistance Protein Activities and Expression to Increased Oral Glibenclamide Exposure in Rats with Streptozotocin-Induced Diabetes Mellitus. Drug Metabolism and Disposition 40:6, pages 1104-1112.
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Karthikeyan Chandrasekaran, Kavitha Swaminathan, S. Mathan Kumar, Dahn L. Clemens & Aparajita Dey. (2012) Increased oxidative stress and toxicity in ADH and CYP2E1 overexpressing human hepatoma VL-17A cells exposed to high glucose. Integrative Biology 4:5, pages 550.
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Tissa T. Manavalan, Yun Teng, Savitri N. Appana, Susmita Datta, Theodore S. Kalbfleisch, Yong Li & Carolyn M. Klinge. (2011) Differential expression of microRNA expression in tamoxifen-sensitive MCF-7 versus tamoxifen-resistant LY2 human breast cancer cells. Cancer Letters 313:1, pages 26-43.
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Aparajita Dey & S. Mathan Kumar. (2011) Cytochrome P450 2E1 and hyperglycemia-induced liver injury. Cell Biology and Toxicology 27:4, pages 285-310.
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Jill E. Skepner, Lorraine D. Shelly, Chengjie Ji, Benjamin Reidich & Yi Luo. (2011) Chronic treatment with epoxyeicosatrienoic acids modulates insulin signaling and prevents insulin resistance in hepatocytes. Prostaglandins & Other Lipid Mediators 94:1-2, pages 3-8.
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Teresa Maria J. P. Carvalho, Ricardo de Carvalho Cavalli, Sérgio P. Cunha, Cláudia O. de Baraldi, Maria P. Marques, Natalícia J. Antunes, Ana Leonor P. C. Godoy & Vera Lucia Lanchote. (2010) Influence of gestational diabetes mellitus on the stereoselective kinetic disposition and metabolism of labetalol in hypertensive patients. European Journal of Clinical Pharmacology 67:1, pages 55-61.
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Joo H Lee, Si H Yang, Jung M Oh & Myung G Lee. (2010) Pharmacokinetics of drugs in rats with diabetes mellitus induced by alloxan or streptozocin: comparison with those in patients with type I diabetes mellitus. Journal of Pharmacy and Pharmacology 62:1, pages 1-23.
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Dae Y. Lee, Hye J. Chung, Young H. Choi, Unji Lee, So H. Kim, Inchul Lee & Myung G. Lee. (2009) Pharmacokinetics of ipriflavone and its two metabolites, M1 and M5, after the intravenous and oral administration of ipriflavone to rat model of diabetes mellitus induced by streptozotocin. European Journal of Pharmaceutical Sciences 38:5, pages 465-471.
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Samuel Carroll BrooksIIIIII, Janie Sue Brooks, Woo Hyung Lee, Myung Gull Lee & Sang Geon Kim. (2009) Therapeutic potential of dithiolethiones for hepatic diseases. Pharmacology & Therapeutics 124:1, pages 31-43.
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Bingning Dong, Mohammed Qatanani & David D. Moore. (2009) Constitutive androstane receptor mediates the induction of drug metabolism in mouse models of type 1 diabetes. Hepatology 50:2, pages 622-629.
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CY Ahn, SK Bae, SH Bae, T Kim, YS Jung, YC Kim, MG Lee & WG Shin. (2009) Pharmacokinetics of oltipraz in diabetic rats with liver cirrhosis. British Journal of Pharmacology 156:6, pages 1019-1028.
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Shahrzad Elmi, Nada A. Sallam, Mohammad M. Rahman, Xiaowei Teng, Arwen L. Hunter, Farzad Moien-Afshari, Majid Khazaei, David J. Granville & Ismail Laher. (2008) Sulfaphenazole treatment restores endothelium-dependent vasodilation in diabetic mice. Vascular Pharmacology 48:1, pages 1-8.
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Yu C. Kim, Hee E. Kang & Myung G. Lee. (2007) Pharmacokinetics of phenytoin and its metabolite, 4′‐HPPH, after intravenous and oral administration of phenytoin to diabetic rats induced by alloxan or streptozotocin. Biopharmaceutics & Drug Disposition 29:1, pages 51-61.
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