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Free Radical Research Volume 40, 2006 - Issue 9
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Original

Effect of polyphenolic extract, Pycnogenol®, on the level of 8-oxoguanine in children suffering from attention deficit/hyperactivity disorder

Zuzana Chovanová Faculty of Medicine, Comenius University, Sasinkova 2, Bratislava, 81108, Slovak Republic
,
Jana Muchová Faculty of Medicine, Comenius University, Sasinkova 2, Bratislava, 81108, Slovak Republic
,
Monika Sivoňová Jessenius Medical Faculty, Comenius University, Department of Medical Chemistry, Biochemistry and Clinical Biochemistry, Malá Hora 4, Martin, 036 01, Slovak Republic
,
Monika Dvořáková Faculty of Medicine, Comenius University, Sasinkova 2, Bratislava, 81108, Slovak Republic
,
Ingrid Žitňanová Faculty of Medicine, Comenius University, Sasinkova 2, Bratislava, 81108, Slovak Republic
,
Iveta Waczulíková Faculty of Mathematics, Physics and Informatics, Comenius University, Department of Nuclear Physics and Biophysics, Division of Biomedical Physics, Mlynská dolina, Bratislava, 4 84248, Slovakia
,
Jana Trebatická Faculty of Medicine, University Hospital, Department of Child Psychiatry, Limbová 1, 833 40, Bratislava, Slovak Republic
,
Igor Škodáček Faculty of Medicine, University Hospital, Department of Child Psychiatry, Limbová 1, 833 40, Bratislava, Slovak Republic
&
Zdeňka Ďuračková Faculty of Medicine, Comenius University, Sasinkova 2, Bratislava, 81108, Slovak RepublicCorrespondence[email protected]
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Pages 1003-1010 | Received 11 May 2006, Published online: 07 Jul 2009

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M. Koláček, J. Muchová, M. Dvořáková, Z. Paduchová, I. Žitňanová, I. Čierna, Z. Országhová, D. Székyová, N. Jajcaiová-Zedníčková, L. Kovács & Z. Ďuračková. (2013) Effect of natural polyphenols (Pycnogenol) on oxidative stress markers in children suffering from Crohn's disease – a pilot study. Free Radical Research 47:8, pages 624-634.
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Julia J Rucklidge, Jeanette Johnstone & Bonnie J Kaplan. (2009) Nutrient supplementation approaches in the treatment of ADHD. Expert Review of Neurotherapeutics 9:4, pages 461-476.
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Monika Dvořáková, Daniela Ježová, Pavol Blažíček, Jana Trebatická, Igor Škodáček, Ján Šuba, Iveta Waczulíková, Peter Rohdewald & Zdeňka Ďuračková. (2007) Urinary catecholamines in children with attention deficit hyperactivity disorder (ADHD): Modulation by a polyphenolic extract from pine bark (Pycnogenol®). Nutritional Neuroscience 10:3-4, pages 151-157.
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Articles from other publishers (69)

R. F. Gasanov, I. V. Makarov, D. A. Emelina & A. S. Avtenuk. (2023) Neuroinflammation and its role in the pathogenesis of attention deficit hyperactivity disorder (literature review). V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY 57:1, pages 8-22.
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Ayyappan Anitha, Ismail Thanseem, Mary Iype & Sanjeev V. Thomas. (2023) Mitochondrial dysfunction in cognitive neurodevelopmental disorders: Cause or effect?. Mitochondrion 69, pages 18-32.
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Dilşad Yıldız Miniksar, Mehmet Akif Cansız, Ayşe Yeşim Göçmen, Mahmut Kılıç & Ökkeş Hakan Miniksar. (2023) The Effect of Drug Use, Body Mass Index and Blood Pressure on Oxidative Stress Levels in Children and Adolescents with Attention Deficit and Hyperactivity Disorder. Clinical Psychopharmacology and Neuroscience 21:1, pages 88-98.
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Rachel SchroederPreethy SridharanLynn NguyenAlexandra LorenNoelle S. WilliamsKavitha P. KettimuthuCoral J. Cintrón-PérezEdwin Vázquez-RosaAndrew A. PieperHanna E. Stevens. (2021) Maternal P7C3-A20 Treatment Protects Offspring from Neuropsychiatric Sequelae of Prenatal Stress. Antioxidants & Redox Signaling 35:7, pages 511-530.
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Cheng‐Dien Hsu, Li‐Hsuan Hsieh, Ya‐Ling Chen, I‐Cheng Lin, Ying‐Ru Chen, Chih‐Chi Chen, Hitoshi Shirakawa & Suh‐Ching Yang. (2021) Complementary effects of pine bark extract supplementation on inattention, impulsivity, and antioxidative status in children with attention‐deficit hyperactivity disorder: A double‐blinded randomized placebo‐controlled cross‐over study. Phytotherapy Research 35:6, pages 3226-3235.
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Frank Schoenlau. 2021. Nutraceuticals in Brain Health and Beyond. Nutraceuticals in Brain Health and Beyond 335 341 .
Naomi Perry, Laura Martin, Frank Rosenfeldt, Ruchong Ou, Renee Rowsell & Con Stough. 2021. Nutraceuticals in Brain Health and Beyond. Nutraceuticals in Brain Health and Beyond 57 80 .
Franziska Weichmann & Peter Rohdewald. (2020) Projected supportive effects of PycnogenolⓇ in patients suffering from multi-dimensional health impairments after a SARS-CoV2 infection. International Journal of Antimicrobial Agents 56:6, pages 106191.
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Lourdes Alvarez-Arellano, Marcela Salazar-García & Juan Carlos Corona. (2020) Neuroprotective Effects of Quercetin in Pediatric Neurological Diseases. Molecules 25:23, pages 5597.
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Juan Carlos Corona. (2020) Role of Oxidative Stress and Neuroinflammation in Attention-Deficit/Hyperactivity Disorder. Antioxidants 9:11, pages 1039.
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Mustafa S. Atta, Foad A. Farrag, Essam A. Almadaly, Hanan A. Ghoneim, Ahmed S. Hafez, Soad K. Al Jaouni, Shaker A. Mousa & Ali H. El-Far. (2020) Transcriptomic and biochemical effects of pycnogenol in ameliorating heat stress-related oxidative alterations in rats. Journal of Thermal Biology 93, pages 102683.
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Nina U Robertson, Anel Schoonees, Amanda Brand & Janicke Visser. (2020) Pine bark ( Pinus spp.) extract for treating chronic disorders . Cochrane Database of Systematic Reviews 2020:9.
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Harry Robberecht, Annelies A. J. Verlaet, Annelies Breynaert, Tess De Bruyne & Nina Hermans. (2020) Magnesium, Iron, Zinc, Copper and Selenium Status in Attention-Deficit/Hyperactivity Disorder (ADHD). Molecules 25:19, pages 4440.
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Yonghong Li, Caihui Cha, XueJing Lv, Jian Liu, Jiaying He, Qihua Pang, Lingxue Meng, Hongxuan Kuang & Ruifang Fan. (2020) Association between 10 urinary heavy metal exposure and attention deficit hyperactivity disorder for children. Environmental Science and Pollution Research 27:25, pages 31233-31242.
Crossref
Joseph Katzinger, Michael T. Murray & Michael R. Lyon. 2020. Textbook of Natural Medicine. Textbook of Natural Medicine 1156 1162.e3 .
Michael T. Murray. 2020. Textbook of Natural Medicine. Textbook of Natural Medicine 823 828.e2 .
Stefano Pallanti & Luana SalernoStefano Pallanti & Luana Salerno. 2020. The Burden of Adult ADHD in Comorbid Psychiatric and Neurological Disorders. The Burden of Adult ADHD in Comorbid Psychiatric and Neurological Disorders 61 86 .
Stefano Pallanti & Luana SalernoStefano Pallanti & Luana Salerno. 2020. The Burden of Adult ADHD in Comorbid Psychiatric and Neurological Disorders. The Burden of Adult ADHD in Comorbid Psychiatric and Neurological Disorders 347 371 .
Sweta Bawari, Devesh Tewari, Sandro Argüelles, Archana N. Sah, Seyed Fazel Nabavi, Suowen Xu, Rosa Anna Vacca, Seyed Mohammad Nabavi & Samira Shirooie. (2019) Targeting BDNF signaling by natural products: Novel synaptic repair therapeutics for neurodegeneration and behavior disorders. Pharmacological Research 148, pages 104458.
Crossref
Tamara Simpson, Christina Kure & Con Stough. (2019) Assessing the Efficacy and Mechanisms of Pycnogenol® on Cognitive Aging From In Vitro Animal and Human Studies. Frontiers in Pharmacology 10.
Crossref
Annelies A. J. Verlaet, Annelies Breynaert, Berten Ceulemans, Tess De Bruyne, Erik Fransen, Luc Pieters, Huub F. J. Savelkoul & Nina Hermans. (2018) Oxidative stress and immune aberrancies in attention-deficit/hyperactivity disorder (ADHD): a case–control comparison. European Child & Adolescent Psychiatry 28:5, pages 719-729.
Crossref
Sevtap Aydın, Merve Bacanlı, Hatice Gül Anlar, Tuğbagül Çal, Nuray Arı, Ülkü Ündeğer Bucurgat, Arif Ahmet Başaran & Nursen Başaran. (2019) Preventive role of Pycnogenol® against the hyperglycemia-induced oxidative stress and DNA damage in diabetic rats. Food and Chemical Toxicology 124, pages 54-63.
Crossref
Annelies Verlaet, Nieke van der Bolt, Ben Meijer, Annelies Breynaert, Tania Naessens, Prokopis Konstanti, Hauke Smidt, Nina Hermans, Huub Savelkoul & Malgorzata Teodorowicz. (2019) Toll-Like Receptor-Dependent Immunomodulatory Activity of Pycnogenol®. Nutrients 11:2, pages 214.
Crossref
Juan Carlos Corona. (2018) Natural Compounds for the Management of Parkinson’s Disease and Attention-Deficit/Hyperactivity Disorder. BioMed Research International 2018, pages 1-12.
Crossref
J L Hess, G C Akutagava-Martins, J D Patak, S J Glatt & S V Faraone. (2017) Why is there selective subcortical vulnerability in ADHD? Clues from postmortem brain gene expression data. Molecular Psychiatry 23:8, pages 1787-1793.
Crossref
Yanru Li, Haibin Zhang, Hongxuan Kuang, Ruifang Fan, Caihui Cha, Guanyong Li, Zhiwei Luo & Qihua Pang. (2018) Relationship between bisphenol A exposure and attention-deficit/ hyperactivity disorder: A case-control study for primary school children in Guangzhou, China. Environmental Pollution 235, pages 141-149.
Crossref
Annelies Verlaet, Carlijn Maasakkers, Nina Hermans & Huub Savelkoul. (2018) Rationale for Dietary Antioxidant Treatment of ADHD. Nutrients 10:4, pages 405.
Crossref
Annelies A. J. Verlaet, Berten Ceulemans, Helene Verhelst, Dirk Van West, Tess De Bruyne, Luc Pieters, Huub F. J. Savelkoul & Nina Hermans. (2017) Effect of Pycnogenol® on attention-deficit hyperactivity disorder (ADHD): study protocol for a randomised controlled trial. Trials 18:1.
Crossref
Jana Trebatická & Igor Škodáček. (2016) ADHD - ADHD and the possibility of alternative therapies. Psychiatrie pro praxi 17:E-verze 2/16, pages e11-e17.
Crossref
James Ahn, Hyung Seok Ahn, Jae Hoon Cheong & Ike dela Peña. (2016) Natural Product-Derived Treatments for Attention-Deficit/Hyperactivity Disorder: Safety, Efficacy, and Therapeutic Potential of Combination Therapy. Neural Plasticity 2016, pages 1-18.
Crossref
Adrian L. Lopresti. (2015) Oxidative and nitrosative stress in ADHD: possible causes and the potential of antioxidant-targeted therapies. ADHD Attention Deficit and Hyperactivity Disorders 7:4, pages 237-247.
Crossref
Nidhin Joseph, Yanli Zhang-James, Andras Perl & Stephen V. Faraone. (2013) Oxidative Stress and ADHD. Journal of Attention Disorders 19:11, pages 915-924.
Crossref
Janet K. Kern, David A. Geier, Lisa K. Sykes, Mark R. Geier & Richard C. Deth. (2012) Are ASD and ADHD a Continuum? A Comparison of Pathophysiological Similarities Between the Disorders. Journal of Attention Disorders 19:9, pages 805-827.
Crossref
Xavier Joya, Oscar Garcia-Algar, Judith Salat-Batlle, Cristina Pujades & Oriol Vall. (2015) Advances in the development of novel antioxidant therapies as an approach for fetal alcohol syndrome prevention. Birth Defects Research Part A: Clinical and Molecular Teratology 103:3, pages 163-177.
Crossref
Magdaléna Vaváková, Zdeňka Ďuračková & Jana Trebatická. (2015) Markers of Oxidative Stress and Neuroprogression in Depression Disorder. Oxidative Medicine and Cellular Longevity 2015, pages 1-12.
Crossref
Jana Trebatická & Zdeňka Ďuračková. (2015) Psychiatric Disorders and Polyphenols: Can They Be Helpful in Therapy?. Oxidative Medicine and Cellular Longevity 2015, pages 1-16.
Crossref
Salik Selek & M. Fatih Ceylan. 2015. Studies on Psychiatric Disorders. Studies on Psychiatric Disorders 143 150 .
Stephen V. Faraone, Cristian Bonvicini & Catia Scassellati. (2014) Biomarkers in the Diagnosis of ADHD – Promising Directions. Current Psychiatry Reports 16:11.
Crossref
Amirhossein Sahebkar. (2013) A Systematic Review and Meta-Analysis of the Effects of Pycnogenol on Plasma Lipids. Journal of Cardiovascular Pharmacology and Therapeutics 19:3, pages 244-255.
Crossref
Zdeňka Ďuračková. 2014. Systems Biology of Free Radicals and Antioxidants. Systems Biology of Free Radicals and Antioxidants 3 38 .
V. Kenan Çelik, Erdal Erşan, Serpil Erşan, Sevtap Bakır & Orhan Dogan. (2013) Plasma catalase, glutathione-s-transferase and total antioxidant activity levels of children with attention deficit and hyperactivity disorder. Advances in Bioscience and Biotechnology 04:02, pages 183-187.
Crossref
Michael Lyon & Michael T. Murray. 2013. Textbook of Natural Medicine. Textbook of Natural Medicine 1252 1259 .
Michael T. Murray. 2013. Textbook of Natural Medicine. Textbook of Natural Medicine 995 1000 .
Z.T. Chowdhury & R.R. Watson. 2013. Bioactive Food as Dietary Interventions for Arthritis and Related Inflammatory Diseases. Bioactive Food as Dietary Interventions for Arthritis and Related Inflammatory Diseases 405 411 .
. (2012) Clinical Roundup: Selected Treatment Options for Attention-Deficit Hyperactivity Disorder. Alternative and Complementary Therapies 18:6, pages 329-335.
Crossref
Suzanne M. Morris, Dayton M. Petibone, Wei‐Jiun Lin, James J. Chen, Benedetto Vitiello, Kristine L. Witt & Donald R. Mattison. (2012) The genetic toxicity of methylphenidate: a review of the current literature. Journal of Applied Toxicology 32:10, pages 756-764.
Crossref
Anel Schoonees, Janicke Visser, Alfred Musekiwa & Jimmy Volmink. (2012) Pycnogenol® (extract of French maritime pine bark) for the treatment of chronic disorders. Cochrane Database of Systematic Reviews.
Crossref
Anel Schoonees, Janicke Visser, Alfred Musekiwa & Jimmy Volmink. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
Patricia S. Brocardo, Joana Gil-Mohapel & Brian R. Christie. (2011) The role of oxidative stress in fetal alcohol spectrum disorders. Brain Research Reviews 67:1-2, pages 209-225.
Crossref
N. Sinn & J. Rucklidge. 2011. Lifetime Nutritional Influences on Cognition, Behaviour and Psychiatric Illness. Lifetime Nutritional Influences on Cognition, Behaviour and Psychiatric Illness 323 358 .
Alya Maimoona, Ismat Naeem, Zeb Saddiqe & Khalid Jameel. (2011) A review on biological, nutraceutical and clinical aspects of French maritime pine bark extract. Journal of Ethnopharmacology 133:2, pages 261-277.
Crossref
. 2011. A Guide to Evidence-based Integrative and Complementary Medicine. A Guide to Evidence-based Integrative and Complementary Medicine 127 150 .
Andreas Johannes Schmidt, Jürgen‐Christian Krieg, Ulrich Michael Hemmeter, Tilo Kircher, Eberhard Schulz, Hans‐Willi Clement & Philip Heiser. (2010) Impact of plant extracts tested in attention‐deficit/hyperactivity disorder treatment on cell survival and energy metabolism in human neuroblastoma SH‐SY5Y cells. Phytotherapy Research 24:10, pages 1549-1553.
Crossref
Peter Rohdewald. 2010. Encyclopedia of Dietary Supplements, Second Edition. Encyclopedia of Dietary Supplements, Second Edition 298 306 .
Andreas Johannes Schmidt, Hans-Willi Clement, Stefan Gebhardt, Ulrich Michael Hemmeter, Eberhard Schulz, Jürgen-Christian Krieg, Tilo Kircher & Philip Heiser. (2010) Impact of psychostimulants and atomoxetine on the expression of 8-hydroxyguanine glycosylase 1 in human cells. Journal of Neural Transmission 117:6, pages 793-797.
Crossref
John Mach, Adrian W. Midgley, Steve Dank, Ross S. Grant & David J. Bentley. (2010) The Effect of Antioxidant Supplementation on Fatigue during Exercise: Potential Role for NAD+(H). Nutrients 2:3, pages 319-329.
Crossref
Susanne Walitza, Kristina Kämpf, Rajaraman Gnana Oli, Andreas Warnke, Manfred Gerlach & Helga Stopper. (2010) Prospective follow-up studies found no chromosomal mutagenicity of methylphenidate therapy in ADHD affected children. Toxicology Letters 193:1, pages 4-8.
Crossref
A.J. Russo. (2010) Decreased Serum Cu/Zn SOD Associated with High Copper in Children with Attention Deficit Hyperactivity Disorder (ADHD). Journal of Central Nervous System Disease 2, pages JCNSD.S4553.
Crossref
Alena Viktorinova, Jana Trebaticka, Zuzana Paduchova, Monika Ursinyova, Iveta Uhnakova, Vlasta Masanova & Zdenka Durackova. (2009) WITHDRAWN: Natural polyphenols modify trace element status and improve clinical symptoms of attention-deficit hyperactivity disorder. Biomedicine & Pharmacotherapy.
Crossref
Marianne M. Glanzman. (2009) ADHD and nutritional supplements. Current Attention Disorders Reports 1:2, pages 75-81.
Crossref
Natalie Sinn. (2008) Nutritional and dietary influences on attention deficit hyperactivity disorder. Nutrition Reviews 66:10, pages 558-568.
Crossref
Felicity Ng, Michael Berk, Olivia Dean & Ashley I. Bush. (2008) Oxidative stress in psychiatric disorders: evidence base and therapeutic implications. The International Journal of Neuropsychopharmacology 11:06.
Crossref
Lívia Križková, Zuzana Chovanová, Zdenka Ďuračková & Juraj Krajčovič. (2007) Antimutagenic in vitro activity of plant polyphenols: Pycnogenol ® and Ginkgo biloba extract (EGb 761) . Phytotherapy Research 22:3, pages 384-388.
Crossref
Zdenka Ďuračková & Anna Gvozdjáková. 2008. Mitochondrial Medicine. Mitochondrial Medicine 19 54 .

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