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Free Radical Research Volume 51, 2017 - Issue 1
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Original Article

Ferulic acid (FA) abrogates γ-radiation induced oxidative stress and DNA damage by up-regulating nuclear translocation of Nrf2 and activation of NHEJ pathway

Ujjal DasDepartment of Physiology, Centre for Nanoscience and Nanotechnology and Centre with Potential for Excellence in Particular Area (CPEPA), University of Calcutta, Kolkata, West Bengal, India;
,
Krishnendu MannaDepartment of Physiology, Centre for Nanoscience and Nanotechnology and Centre with Potential for Excellence in Particular Area (CPEPA), University of Calcutta, Kolkata, West Bengal, India;
,
Amitava KhanDepartment of Physiology, Centre for Nanoscience and Nanotechnology and Centre with Potential for Excellence in Particular Area (CPEPA), University of Calcutta, Kolkata, West Bengal, India;
,
Mahuya SinhaDepartment of Physiology, Centre for Nanoscience and Nanotechnology and Centre with Potential for Excellence in Particular Area (CPEPA), University of Calcutta, Kolkata, West Bengal, India;
,
Sushobhan BiswasDepartment of Physiology, Centre for Nanoscience and Nanotechnology and Centre with Potential for Excellence in Particular Area (CPEPA), University of Calcutta, Kolkata, West Bengal, India;
,
Aaveri SenguptaDepartment of Physiology, Centre for Nanoscience and Nanotechnology and Centre with Potential for Excellence in Particular Area (CPEPA), University of Calcutta, Kolkata, West Bengal, India;
,
Anindita ChakrabortyDivision of Radiation Biology, UGC-DAE CSR Center Kolkata, Kolkata, West Bengal, India
&
Sanjit DeyDepartment of Physiology, Centre for Nanoscience and Nanotechnology and Centre with Potential for Excellence in Particular Area (CPEPA), University of Calcutta, Kolkata, West Bengal, India; Correspondence[email protected]
 show all
Pages 47-63 | Received 24 Jul 2016, Accepted 29 Nov 2016, Published online: 11 Jan 2017

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Md Arman Islam, Maisha Maliha Medha, Akhlak Un Nahar, Md Abdullah Al Fahad, Md Afjalus Siraj & Veronique Seidel. (2023) Cancer Protective Role of Selected Dietary Polyphenols via Modulating Keap1/Nrf2/ARE and Interconnected Signaling Pathways. Nutrition and Cancer 75:4, pages 1065-1102.
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Sushobhan Biswas, Hrishita Das, Ujjal Das, Aaveri Sengupta, Rakhi Dey Sharma, Subhas Chandra Biswas & Sanjit Dey. (2020) Smokeless tobacco induces toxicity and apoptosis in neuronal cells: a mechanistic evaluation. Free Radical Research 54:7, pages 477-496.
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Mohsen Sisakht, Maryam Darabian, Amir Mahmoodzadeh, Ali Bazi, Sayed Mohammad Shafiee, Pooneh Mokarram & Zahra Khoshdel. (2020) The role of radiation induced oxidative stress as a regulator of radio-adaptive responses. International Journal of Radiation Biology 96:5, pages 561-576.
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Guowen Zhang, Zhisheng Zhou, Jianjian Xu, Yijing Liao & Xing Hu. (2020) Groove binding between ferulic acid and calf thymus DNA: spectroscopic methodology combined with chemometrics and molecular docking studies. Journal of Biomolecular Structure and Dynamics 38:7, pages 2029-2037.
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Ujjal Das, Krishnendu Manna, Arghya Adhikary, Snehasis Mishra, Krishna Das Saha, Rakhi Dey Sharma, Biswanath Majumder & Sanjit Dey. (2019) Ferulic acid enhances the radiation sensitivity of lung and liver carcinoma cells by collapsing redox homeostasis: mechanistic involvement of Akt/p38 MAPK signalling pathway. Free Radical Research 53:9-10, pages 944-967.
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Ujjal Das, Aaveri Sengupta, Sushobhan Biswas, Arghya Adhikary, Rakhi Dey Sharma, Anindita Chakraborty & Sanjit Dey. (2017) Alteration of murine duodenal morphology and redox signalling events by reactive oxygen species generated after whole body γ-irradiation and its prevention by ferulic acid. Free Radical Research 51:11-12, pages 886-910.
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Yiman Zhai, Tingyu Wang, Yunmei Fu, Tong Yu, Yan Ding & Hongguang Nie. (2023) Ferulic Acid: A Review of Pharmacology, Toxicology, and Therapeutic Effects on Pulmonary Diseases. International Journal of Molecular Sciences 24:9, pages 8011.
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