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Article

Suppression of NRF2/ARE by convallatoxin sensitises A549 cells to 5-FU-mediated apoptosis

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Pages 1416-1423 | Received 30 Dec 2017, Accepted 09 Jun 2018, Published online: 10 Sep 2018

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Darinka Gjorgieva Ackova, Viktorija Maksimova, Katarina Smilkov, Brigitta Buttari, Marzia Arese & Luciano Saso. (2023) Alkaloids as Natural NRF2 Inhibitors: Chemoprevention and Cytotoxic Action in Cancer. Pharmaceuticals 16:6, pages 850.
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Rohini Srivastava, Raquel Fernández-Ginés, José Antonio Encinar, Antonio Cuadrado & Geoff Wells. (2022) The current status and future prospects for therapeutic targeting of KEAP1-NRF2 and β-TrCP-NRF2 interactions in cancer chemoresistance. Free Radical Biology and Medicine 192, pages 246-260.
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Madhunika Agrawal & Satyam Kumar Agrawal. 2022. Handbook of Oxidative Stress in Cancer: Therapeutic Aspects. Handbook of Oxidative Stress in Cancer: Therapeutic Aspects 1577 1593 .
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Chorlada Paiboonrungruang, Emily Simpson, Zhaohui Xiong, Caizhi Huang, Jianying Li, Yahui Li & Xiaoxin Chen. (2021) Development of targeted therapy of NRF2high esophageal squamous cell carcinoma. Cellular Signalling 86, pages 110105.
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Lingyan Zhang, Jian Zhang, Yuanqing Jin, Gang Yao, Hai Zhao, Penghai Qiao & Shuguang Wu. (2021) Nrf2 Is a Potential Modulator for Orchestrating Iron Homeostasis and Redox Balance in Cancer Cells. Frontiers in Cell and Developmental Biology 9.
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Le Ba Nam, Won Jun Choi & Young-Sam Keum. (2021) Triptolide Downregulates the Expression of NRF2 Target Genes by Increasing Cytoplasmic Localization of NRF2 in A549 Cells. Frontiers in Pharmacology 12.
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Miriam Sánchez-Ortega, Ana Clara Carrera & Antonio Garrido. (2021) Role of NRF2 in Lung Cancer. Cells 10:8, pages 1879.
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Emiliano PanieriLuciano Saso. (2021) Inhibition of the NRF2/KEAP1 Axis: A Promising Therapeutic Strategy to Alter Redox Balance of Cancer Cells. Antioxidants & Redox Signaling 34:18, pages 1428-1483.
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Pelin Telkoparan-Akillilar, Emiliano Panieri, Dilek Cevik, Sibel Suzen & Luciano Saso. (2021) Therapeutic Targeting of the NRF2 Signaling Pathway in Cancer. Molecules 26:5, pages 1417.
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Azhwar Raghunath, Raju Nagarajan & Kiruthika Sundarraj. 2021. Targeting Cellular Signalling Pathways in Lung Diseases. Targeting Cellular Signalling Pathways in Lung Diseases 661 682 .
Ramin Pourakbari, Sanaz Mansouri Taher, Bashir Mosayyebi, Mohammad Hosein Ayoubi-Joshaghani, Hamid Ahmadi & Leili Aghebati-Maleki. (2020) Implications for glycosylated compounds and their anti-cancer effects. International Journal of Biological Macromolecules 163, pages 1323-1332.
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Jong-Su Kang, Le Ba Nam, Ok-Kyung Yoo & Young-Sam Keum. (2020) Molecular mechanisms and systemic targeting of NRF2 dysregulation in cancer. Biochemical Pharmacology 177, pages 114002.
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Jong-Su Kang, June Lee, Le Ba Nam, Ok-Kyung Yoo, Kim-Thanh Pham, Thi-Hoai-Men Duong & Young-Sam Keum. (2019) Homoharringtonine stabilizes secondary structure of guanine-rich sequence existing in the 5′-untranslated region of Nrf2. Bioorganic & Medicinal Chemistry Letters 29:16, pages 2189-2196.
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Emiliano Panieri & Luciano Saso. (2019) Potential Applications of NRF2 Inhibitors in Cancer Therapy. Oxidative Medicine and Cellular Longevity 2019, pages 1-34.
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Jinshui He, Xu Zhang, Chaowei Lian, Jinzhi Wu, Yanling Fang & Xiaoling Ye. (2019) RETRACTED: Exendin-4 prevented pancreatic beta cells from apoptosis in (Type I) diabetic mouse via keap1-Nrf2 signaling. Experimental Biology and Medicine 244:1, pages 28-35.
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