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Free Radical Research Volume 29, 1998 - Issue 6
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Original Article

Methodological considerations and factors affecting 8-hydroxy-2′-deoxyguanosine analysis

Lennart Möller Karolinska Institutet, Department of Biosciences, Unit for Analytical Toxicology, SE-141 57, Huddinge, Stockholm, Sweden
,
Tim Hofer Karolinska Institutet, Department of Biosciences, Unit for Analytical Toxicology, SE-141 57, Huddinge, Stockholm, Sweden
&
Magnus Zeisig Karolinska Institutet, Department of Biosciences, Unit for Analytical Toxicology, SE-141 57, Huddinge, Stockholm, Sweden
Pages 511-524 | Received 14 Jul 1998, Published online: 07 Jul 2009

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I. Kato, J. Ren, L. K. Heilbrun & Zora Djuric. (2006) Intra- and inter-individual variability in measurements of biomarkers for oxidative damage in vivo: Nutrition and Breast Health Study. Biomarkers 11:2, pages 143-152.
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Tim Hofer, Hanna L. Karlsson & Lennart Möller. (2006) DNA oxidative damage and strand breaks in young healthy individuals: A gender difference and the role of life style factors. Free Radical Research 40:7, pages 707-714.
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Kevin Pong. (2003) Oxidative stress in neurodegenerative diseases: therapeutic implications for superoxide dismutase mimetics. Expert Opinion on Biological Therapy 3:1, pages 127-139.
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Gunther Guetens, Gert De Boeck, Martin Highley, Allan T. van Oosterom & Ernst A. de Bruijn. (2002) Oxidative DNA Damage: Biological Significance and Methods of Analysis. Critical Reviews in Clinical Laboratory Sciences 39:4-5, pages 331-457.
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Articles from other publishers (24)

Weidong Hu, Zhengke He, Lin Du, Li Zhang, Jun Li, Yue Ma & Shicheng Bi. (2023) Biomarkers of oxidative stress in broiler chickens attacked by lipopolysaccharide: A systematic review and meta-analysis. Ecotoxicology and Environmental Safety 266, pages 115606.
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Adeyemi O. Adedeji, Tony Pourmohamad, Niraj Tripathi, Shelly Zhong, Kenna R. Degner, Fiona Zhong, Dewakar Sangaraju, Kevin Williams & Noel Dybdal. (2023) Reduced Fasting Duration in Cynomolgus Monkeys Enhances Animal Welfare During Toxicology Studies. Toxicologic Pathology.
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Tim Hofer. (2021) Oxidative Stress in Human Toxicology. Antioxidants 10:8, pages 1159.
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Mostafa I. Waly. 2021. Nutritional Management and Metabolic Aspects of Hyperhomocysteinemia. Nutritional Management and Metabolic Aspects of Hyperhomocysteinemia 1 7 .
Rao M. Uppu, Danial Woods & Narasimham L. Parinandi. 2020. Measuring Oxidants and Oxidative Stress in Biological Systems. Measuring Oxidants and Oxidative Stress in Biological Systems 123 131 .
Tim Hofer & George Perry. (2016) Nucleic acid oxidative damage in Alzheimer's disease—explained by the hepcidin-ferroportin neuronal iron overload hypothesis?. Journal of Trace Elements in Medicine and Biology 38, pages 1-9.
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. 2002. The MAK-Collection for Occupational Health and Safety. The MAK-Collection for Occupational Health and Safety 1 24 .
Fiona A. Summers, Ronald P. Mason & Marilyn Ehrenshaft. (2013) Development of immunoblotting techniques for DNA radical detection. Free Radical Biology and Medicine 56, pages 64-71.
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A. Pilger. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 41 57 .
A. Paini, G. Scholz, M. Marin-Kuan, B. Schilter, J. O'Brien, P. J. van Bladeren & I. M. C. M. Rietjens. (2011) Quantitative comparison between in vivo DNA adduct formation from exposure to selected DNA-reactive carcinogens, natural background levels of DNA adduct formation and tumour incidence in rodent bioassays. Mutagenesis 26:5, pages 605-618.
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Hanna L. Karlsson & Lennart Möller. 2011. Studies on Experimental Models. Studies on Experimental Models 605 620 .
Siu-Wai Choi, Iris F.F. Benzie, Shuk-Woon Ma, J.J. Strain & Bernadette M. Hannigan. (2008) Acute hyperglycemia and oxidative stress: Direct cause and effect?. Free Radical Biology and Medicine 44:7, pages 1217-1231.
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Mu-Rong Chao, Cheng-Chieh Yen & Chiung-Wen Hu. (2008) Prevention of artifactual oxidation in determination of cellular 8-oxo-7,8-dihydro-2′-deoxyguanosine by isotope-dilution LC–MS/MS with automated solid-phase extraction. Free Radical Biology and Medicine 44:3, pages 464-473.
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A. Pilger & H. W. Rüdiger. (2006) 8-Hydroxy-2′-deoxyguanosine as a marker of oxidative DNA damage related to occupational and environmental exposures. International Archives of Occupational and Environmental Health 80:1, pages 1-15.
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Clemens von Sonntag. 2006. Free-Radical-Induced DNA Damage and Its Repair. Free-Radical-Induced DNA Damage and Its Repair 483 504 .
J.M. Weiss, E.L. Goode, W.C. Ladiges & Cornelia M. Ulrich. (2005) Polymorphic variation inhOGG1 and risk of cancer: A review of the functional and epidemiologic literature. Molecular Carcinogenesis 42:3, pages 127-141.
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Isabel A Rebelo, José António P Piedade & Ana Maria Oliveira-Brett. (2004) Development of an HPLC method with electrochemical detection of femtomoles of 8-oxo-7,8-dihydroguanine and 8-oxo-7,8-dihydro-2′-deoxyguanosine in the presence of uric acid. Talanta 63:2, pages 323-331.
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Richard A Frank, Douglas Galasko, Harald Hampel, John Hardy, Mony J de Leon, Pankaj D Mehta, Joseph Rogers, Eric Siemers & John Q Trojanowski. (2003) Biological markers for therapeutic trials in Alzheimer’s disease. Neurobiology of Aging 24:4, pages 521-536.
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James A. Swenberg, Amy‐Joan L. Ham, Hasan Koc, David K. La, Eric J. Morinello, Brian F. Pachkowski, Asoka Ranasinghe & Patricia B. Upton. (2002) Methods for Measuring DNA Adducts and Abasic Sites II: Methods for Measurement of DNA Adducts . Current Protocols in Toxicology 12:1.
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Xi Huang, Juliana Powell, Laverne A Mooney, Chenlu Li & Krystyna Frenkel. (2001) Importance of complete DNA digestion in minimizing variability of 8-oxo-dG analyses. Free Radical Biology and Medicine 31:11, pages 1341-1351.
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HAN-MING SHEN & CHOON-NAM ONG. 2001. Bio-Assays for Oxidative Stress Status. Bio-Assays for Oxidative Stress Status 89 96 .
Ulrike Sattler, Patrick Calsou, Serge Boiteux & Bernard Salles. (2000) Detection of Oxidative Base DNA Damage by a New Biochemical Assay. Archives of Biochemistry and Biophysics 376:1, pages 26-33.
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Han-Ming Shen & Choon-Nam Ong. (2000) Detection of oxidative DNA damage in human sperm and its association with sperm function and male infertility. Free Radical Biology and Medicine 28:4, pages 529-536.
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Andrew R Collins. (1998) Molecular epidemiology in cancer research. Molecular Aspects of Medicine 19:6, pages 359-432.
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