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Drug Delivery Volume 9, 2002 - Issue 1
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Research Article

Low Concentrations of Chlorpromazine and Related Phenothiazines Stimulate Gene Transfer in HeLa Cells Via Receptor-Mediated Endocytosis

Arthur Hawtrey Department of Pharmacology, University of Stellenbosch Medical School, Tygerberg, South Africa
,
Daniel Joubert Department of Pharmacology, University of Stellenbosch Medical School, Tygerberg, South Africa
,
Pieter van Jaarsveld Department of Pharmacology, University of Stellenbosch Medical School, Tygerberg, South Africa
,
Anton Pieterse Department of Pharmacology, University of Stellenbosch Medical School, Tygerberg, South Africa
,
Johann van Zyl Department of Pharmacology, University of Stellenbosch Medical School, Tygerberg, South Africa
&
Mario Ariatti Department of Biochemistry, University of Durban-Westville, Durban, South Africa
Pages 47-53 | Published online: 29 Sep 2008

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Sadhna Sharma & Amandeep Singh. (2011) Phenothiazines as anti-tubercular agents: mechanistic insights and clinical implications. Expert Opinion on Investigational Drugs 20:12, pages 1665-1676.
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Articles from other publishers (8)

Samar Sami Alkafaas, Abanoub Mosaad Abdallah, Soumya Ghosh, Samah A. Loutfy, Sara Samy Elkafas, Nasra F. Abdel Fattah & Mohamed Hessien. (2022) Insight into the role of clathrin‐mediated endocytosis inhibitors in SARS‐CoV‐2 infection. Reviews in Medical Virology 33:1.
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Timo Buhl, Andrea Braun, Susann Forkel, Wiebke Möbius, Lars van Werven, Olaf Jahn, Nasrollah Rezaei-Ghaleh, Markus Zweckstetter, Martin Mempel, Michael P. Schön & Holger A. Haenssle. (2014) Internalization routes of cell-penetrating melanoma antigen peptides into human dendritic cells. Experimental Dermatology 23:1, pages 20-26.
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Gangopadhyay Sudeshna & Karmakar Parimal. (2010) Multiple non-psychiatric effects of phenothiazines: A review. European Journal of Pharmacology 648:1-3, pages 6-14.
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J. J. Aaron, M. D. Gaye Seye, S. Trajkovska & N. Motohashi. 2009. Bioactive Heterocycles VII. Bioactive Heterocycles VII 153 231 .
Lawrence B. Hendry, Virendra B. Mahesh, Edwin D. BransomeJr.Jr. & Douglas E. Ewing. (2007) Small molecule intercalation with double stranded DNA: Implications for normal gene regulation and for predicting the biological efficacy and genotoxicity of drugs and other chemicals. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 623:1-2, pages 53-71.
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Birgit Neukamm, Andreas Weimann, Shuling Wu, Margrete Danevad, Christine Lang & Reinhard Geßner. (2006) Novel two-stage screening procedure leads to the identification of a new class of transfection enhancers. The Journal of Gene Medicine 8:6, pages 745-753.
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P Medberry, S Dennis, T Van Hecke & R.K DeLong. (2004) pDNA bioparticles: comparative heterogeneity, surface, binding, and activity analyses. Biochemical and Biophysical Research Communications 319:2, pages 426-432.
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M. F. Yanze, W.-S. Lee, K. Poon, M. Piquette-Miller & R. B. Macgregor. (2003) Cellular Uptake and Metabolism of DNA Frayed Wires. Biochemistry 42:39, pages 11427-11433.
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