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Drug Delivery Volume 24, 2017 - Issue 1
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Research Article

Reduction-responsive PEtOz-SS-PCL micelle with tailored size to overcome blood–brain barrier and enhance doxorubicin antiglioma effect

Yuling Lia Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, PR China; ;b Brain Hospital, Affiliated Hospital of Xuzhou Medical University, Xuzhou, PR China; ;c Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, School of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou, PR ChinaView further author information
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Li Baiyanga Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, PR China; ;b Brain Hospital, Affiliated Hospital of Xuzhou Medical University, Xuzhou, PR China; View further author information
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Bu Leranc Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, School of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou, PR ChinaView further author information
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Wang Zhena Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, PR China; ;b Brain Hospital, Affiliated Hospital of Xuzhou Medical University, Xuzhou, PR China; View further author information
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Xie Yandonga Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, PR China; ;b Brain Hospital, Affiliated Hospital of Xuzhou Medical University, Xuzhou, PR China; View further author information
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Du Baixiangc Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, School of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou, PR ChinaView further author information
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Zhu Dandanc Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, School of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou, PR ChinaView further author information
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Zhu Yufua Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, PR China; ;b Brain Hospital, Affiliated Hospital of Xuzhou Medical University, Xuzhou, PR China; View further author information
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Liang Juna Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, PR China; ;b Brain Hospital, Affiliated Hospital of Xuzhou Medical University, Xuzhou, PR China; Correspondence[email protected]
View further author information
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Yu Rutonga Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, PR China; ;b Brain Hospital, Affiliated Hospital of Xuzhou Medical University, Xuzhou, PR China; Correspondence[email protected]
View further author information
&
Liu Hongmeia Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, PR China; ;b Brain Hospital, Affiliated Hospital of Xuzhou Medical University, Xuzhou, PR China; Correspondence[email protected]
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Pages 1782-1790 | Received 25 Aug 2017, Accepted 04 Nov 2017, Published online: 24 Nov 2017

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Marzieh Kazemi, Masoomeh Nazarabi, Zahra Niazi & Mohsen Ashjari. (2022) Well-defined synthesis of poly(2-isopropyl-2-oxazoline)-based copolymer for delivery of doxorubicin by multi-sensitive nano-micelle. International Journal of Polymeric Materials and Polymeric Biomaterials 71:17, pages 1359-1368.
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Zhenkun Zong, Lei Hua, Zhen Wang, Haoyue Xu, Chengkun Ye, Bomin Pan, Zongren Zhao, Longzhen Zhang, Jun Lu, Hongmei Liu & Rutong Yu. (2019) Self-assembled angiopep-2 modified lipid-poly (hypoxic radiosensitized polyprodrug) nanoparticles delivery TMZ for glioma synergistic TMZ and RT therapy. Drug Delivery 26:1, pages 34-44.
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Saba Nemati Mahand, Sanaz Aliakbarzadeh, Armaghan Moghaddam, Abolfazl Salehi Moghaddam, Benjamin Kruppke, Mahmoud Nasrollahzadeh & Hossein Ali Khonakdar. (2022) Polyoxazoline: A review article from polymerization to smart behaviors and biomedical applications. European Polymer Journal 178, pages 111484.
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Edurne Luque-Michel, Laurent Lemaire & Maria J. Blanco-Prieto. (2021) SPION and doxorubicin-loaded polymeric nanocarriers for glioblastoma theranostics. Drug Delivery and Translational Research 11:2, pages 515-523.
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Hena Zhang, Xiaojun Liu, Ting Xu, Kang Xu, Baixiang Du & Yuling Li. (2020) Biodegradable reduction and pH dual-sensitive polymer micelles based on poly(2-ethyl-2-oxazoline) for efficient delivery of curcumin. RSC Advances 10:43, pages 25435-25445.
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Somdeb Jana & Mariusz Uchman. (2020) Poly(2-oxazoline)-based stimulus-responsive (Co)polymers: An overview of their design, solution properties, surface-chemistries and applications. Progress in Polymer Science 106, pages 101252.
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Edouard Alphandéry. (2020) Nano-Therapies for Glioblastoma Treatment. Cancers 12:1, pages 242.
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Guillaume Delaittre. (2019) Telechelic poly(2-oxazoline)s. European Polymer Journal 121, pages 109281.
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Chengkun Ye, Bomin Pan, Haoyue Xu, Zongren Zhao, Jiawei Shen, Jun Lu, Rutong Yu & Hongmei Liu. (2019) Co-delivery of GOLPH3 siRNA and gefitinib by cationic lipid-PLGA nanoparticles improves EGFR-targeted therapy for glioma. Journal of Molecular Medicine 97:11, pages 1575-1588.
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Xiaoli Wu, Han Yang, Weitao Yang, Xingmeng Chen, Junxiao Gao, Xiaoqun Gong, Hanjie Wang, Yue Duan, Daohe Wei & Jin Chang. (2019) Nanoparticle-based diagnostic and therapeutic systems for brain tumors. Journal of Materials Chemistry B 7:31, pages 4734-4750.
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Juhi Samal, Ana Lucia Rebelo & Abhay Pandit. (2019) A window into the brain: Tools to assess pre-clinical efficacy of biomaterials-based therapies on central nervous system disorders. Advanced Drug Delivery Reviews 148, pages 68-145.
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Wei Tang, Wenpei Fan, Joseph Lau, Liming Deng, Zheyu Shen & Xiaoyuan Chen. (2019) Emerging blood–brain-barrier-crossing nanotechnology for brain cancer theranostics. Chemical Society Reviews 48:11, pages 2967-3014.
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