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Drug Delivery Volume 25, 2018 - Issue 1
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Research Article

Preparation and evaluation of injectable Rasagiline mesylate dual-controlled drug delivery system for the treatment of Parkinson’s disease

Ying JiangSchool of Pharmacy, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Yantai University, Yantai, Shandong Province, PR China; View further author information
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Xuemei ZhangSchool of Pharmacy, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Yantai University, Yantai, Shandong Province, PR China; ;State Key Laboratory of Long-Acting and Targeting Drug Delivery System, Shandong Luye Pharmaceutical Co., Ltd, Yantai, Shandong Province, PR ChinaView further author information
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Hongjie MuSchool of Pharmacy, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Yantai University, Yantai, Shandong Province, PR China; View further author information
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Hongchen HuaSchool of Pharmacy, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Yantai University, Yantai, Shandong Province, PR China; View further author information
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Dongyu DuanSchool of Pharmacy, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Yantai University, Yantai, Shandong Province, PR China; View further author information
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Xiuju YanSchool of Pharmacy, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Yantai University, Yantai, Shandong Province, PR China; View further author information
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Yiyun WangSchool of Pharmacy, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Yantai University, Yantai, Shandong Province, PR China; View further author information
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Qingqing MengSchool of Pharmacy, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Yantai University, Yantai, Shandong Province, PR China; View further author information
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Xiaoyan LuSchool of Pharmacy, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Yantai University, Yantai, Shandong Province, PR China; View further author information
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Aiping WangSchool of Pharmacy, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Yantai University, Yantai, Shandong Province, PR China; Correspondence[email protected] [email protected]
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Wanhui LiuSchool of Pharmacy, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Yantai University, Yantai, Shandong Province, PR China; ;State Key Laboratory of Long-Acting and Targeting Drug Delivery System, Shandong Luye Pharmaceutical Co., Ltd, Yantai, Shandong Province, PR ChinaView further author information
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Youxin LiSchool of Pharmacy, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Yantai University, Yantai, Shandong Province, PR China; ;State Key Laboratory of Long-Acting and Targeting Drug Delivery System, Shandong Luye Pharmaceutical Co., Ltd, Yantai, Shandong Province, PR ChinaView further author information
&
Kaoxiang SunSchool of Pharmacy, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Yantai University, Yantai, Shandong Province, PR China; Correspondence[email protected] [email protected]
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Pages 143-152 | Received 26 Oct 2017, Accepted 17 Dec 2017, Published online: 23 Dec 2017

Citations (14)

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Read on this site (1)

Nikhil R. Bali, Mahesh P. Shinde, Shahadev B. Rathod & Pramod S. Salve. (2021) Enhanced transdermal permeation of rasagiline mesylate nanoparticles: design, optimization, and effect of binary combinations of solvent systems across biological membrane. International Journal of Polymeric Materials and Polymeric Biomaterials 70:3, pages 158-173.
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Articles from other publishers (13)

Anjali K. Pandya, Lalitkumar K. Vora, Chukwuebuka Umeyor, Dhanashree Surve, Akanksha Patel, Swati Biswas, Ketankumar Patel & Vandana B. Patravale. (2023) Polymeric in situ forming depots for long-acting drug delivery systems. Advanced Drug Delivery Reviews 200, pages 115003.
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Paramita Saha, Himanshu Kathuria & Murali Monohar Pandey. (2023) Intranasal nanotherapeutics for brain targeting and clinical studies in Parkinson's disease. Journal of Controlled Release 358, pages 293-318.
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Yaquelyn Casanova, Sofía Negro, Karla Slowing, Luis García-García, Ana Fernández-Carballido, Mahdieh Rahmani & Emilia Barcia. (2022) Micro- and Nano-Systems Developed for Tolcapone in Parkinson’s Disease. Pharmaceutics 14:5, pages 1080.
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Yu-Yan Tan, Peter Jenner & Sheng-Di Chen. (2022) Monoamine Oxidase-B Inhibitors for the Treatment of Parkinson’s Disease: Past, Present, and Future. Journal of Parkinson's Disease 12:2, pages 477-493.
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Essyrose Mathew, Sarah A. Stewart, Emilia Utomo, Eneko Larrañeta & Dimitrios A. Lamprou. 2022. Long-Acting Drug Delivery Systems. Long-Acting Drug Delivery Systems 223 248 .
Sonali S. Bharate. (2021) Modulation of biopharmaceutical properties of drugs using sulfonate counterions: A critical analysis of FDA-approved pharmaceutical salts. Journal of Drug Delivery Science and Technology 66, pages 102913.
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Feng Yan, Xiang Cheng, Ming Zhao, Shenghui Gong, Ying Han, Liping Ding, Di Wu, Yumin Luo, Wei Zuo, Lingling Zhu, Ming Fan & Xunming Ji. (2021) Loss of Wip1 aggravates brain injury after ischaemia/reperfusion by overactivating microglia. Stroke and Vascular Neurology 6:3, pages 344-351.
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Nikhil R. Bali & Pramod S. Salve. (2020) Impact of rasagiline nanoparticles on brain targeting efficiency via gellan gum based transdermal patch: A nanotheranostic perspective for Parkinsonism. International Journal of Biological Macromolecules 164, pages 1006-1024.
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Wan Sun, Xiaonan Shi, Chen Chen, Yan‐Ping Zhu, Zhengyu Liu & Bolin Zhu. (2020) Palladium‐Catalyzed Cascade Cyclization/Alkynylation of Alkene‐Tethered Carbamoyl Chlorides with Terminal Alkynes: Synthesis of Alkyne‐Functionalized Oxindoles. Asian Journal of Organic Chemistry 9:4, pages 575-578.
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Yingying Zhang, Chen Chen, Jinghui Zhao & Guiyan Liu. (2019) Rhodium‐Catalyzed Cascade Radical Cyclization of 1,6‐Enynes with Br−CX 3 : Access to Bromine‐Containing Trihalomethylated Pyrrolidines . Asian Journal of Organic Chemistry 8:12, pages 2249-2256.
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Xiaoyu Liu, Lifeng Luo, Pan Qi, Yi Liu, Tian Yin, Jingxin Gou, Haibing He, Yu Zhang & Xing Tang. (2019) A Comprehensive Preclinical Evaluation of Intravenous Etoposide Lipid Emulsion. Pharmaceutical Research 36:7.
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W. S. Galvão, B. B. Pinheiro, L. R. B. Golçalves, M. C. de Mattos, T. S. Fonseca, T. Regis, D. Zampieri, J. C. S. dos Santos, L. S. Costa, M. A. Correa, F. Bohn & P. B. A. Fechine. (2018) Novel nanohybrid biocatalyst: application in the kinetic resolution of secondary alcohols. Journal of Materials Science 53:20, pages 14121-14137.
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