3,316
Views
39
CrossRef citations to date
0
Altmetric
Research Article

Liver-targeted delivery of insulin-loaded nanoparticles via enterohepatic circulation of bile acids

, , &
Pages 1224-1233 | Received 12 Feb 2018, Accepted 16 Apr 2018, Published online: 23 May 2018

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Tzu-Hao Huang, Chih-Jung Chen, Hsin-Chia Angela Lin, Chun-Han Chen & Jia-You Fang. (2023) Self-Nanoemulsifying Drug Delivery System-Containing the Poorly Absorbed Drug – Valsartan in Post-Bariatric Surgery. International Journal of Nanomedicine 18, pages 2647-2658.
Read now
Shiyun Liu, Xiangce Wen, Xin Zhang & Shirui Mao. (2023) Oral delivery of biomacromolecules by overcoming biological barriers in the gastrointestinal tract: an update. Expert Opinion on Drug Delivery 20:10, pages 1333-1347.
Read now
Yujia Liu, Xiaoyu Lu, Zhenhai Zhang, Shulong Jiang & Huixia Lv. (2022) mPEG-Cholic acid/TPGS mixed micelles for combined delivery of paclitaxel and bufalin to treat hepatocellular carcinoma. Pharmaceutical Development and Technology 27:2, pages 215-227.
Read now
Chun Y. Wong, Hani Al-Salami & Crispin R. Dass. (2021) Fabrication techniques for the preparation of orally administered insulin nanoparticles. Journal of Drug Targeting 29:4, pages 365-386.
Read now
Chun Y. Wong, Hani Al-Salami & Crispin R. Dass. (2020) Current status and applications of animal models in pre-clinical development of orally administered insulin-loaded nanoparticles. Journal of Drug Targeting 28:9, pages 882-903.
Read now
Chun Y. Wong, Hani. Al-Salami & Crispin R. Dass. (2020) Cellular assays and applied technologies for characterisation of orally administered protein nanoparticles: a systematic review. Journal of Drug Targeting 28:6, pages 585-599.
Read now

Articles from other publishers (33)

Atefeh Naseri, Somayeh Taymouri, Ali Hosseini Sharifabadi & Jaleh Varshosaz. (2023) Chrysin loaded bilosomes improve the hepatoprotective effects of chrysin against CCl4 induced hepatotoxicity in mice. Journal of Biomaterials Applications 38:4, pages 509-526.
Crossref
Vincent Lenders, Xanthippi Koutsoumpou, Philana Phan, Stefaan J. Soenen, Karel Allegaert, Steven de Vleeschouwer, Jaan Toelen, Zongmin Zhao & Bella B. Manshian. (2023) Modulation of engineered nanomaterial interactions with organ barriers for enhanced drug transport. Chemical Society Reviews 52:14, pages 4672-4724.
Crossref
Melbha Starlin Chellathurai, Chung Lip Yong, Zarif Mohamed Sofian, Shariza Sahudin, Najihah Binti Mohd Hasim & Syed Mahmood. (2023) Self-assembled chitosan-insulin oral nanoparticles — A critical perspective review. International Journal of Biological Macromolecules 243, pages 125125.
Crossref
Yuhong Ma, Qihang Li, Jingru Yang, Yuan Cheng, Caihua Li, Changshun Zhao, Wei Chen, Dechun Huang & Hongliang Qian. (2023) Crosslinked zwitterionic microcapsules to overcome gastrointestinal barriers for oral insulin delivery. Biomaterials Science 11:3, pages 975-984.
Crossref
Gergely Gyimesi & Matthias A. Hediger. (2023) Transporter-Mediated Drug Delivery. Molecules 28:3, pages 1151.
Crossref
Xiaoyan Bao, Kang Qian, Mengjiao Xu, Yi Chen, Hao Wang, Ting Pan, Zhengyi Wang, Ping Yao & Li Lin. (2023) Intestinal epithelium penetration of liraglutide via cholic acid pre-complexation and zein/rhamnolipids nanocomposite delivery. Journal of Nanobiotechnology 21:1.
Crossref
De-sheng Cai, Shao-Yan Lou, Su Huo, Yu-Qin Yang, Feng Gao, Wen-Min Pi, Ke-Dian Chen, Cheng Wang, Xiao-Yun Yang, Jing-Yi Jiao, Bing Xu, Peng-Long Wang & Hai-Min Lei. (2022) Synthesis and biological activity evaluation of podophyllotoxin-linked bile acid derivatives as potential anti-liver cancer agents. Bioorganic Chemistry 128, pages 106066.
Crossref
Leqi Wang, Qi Liu, Xinping Hu, Chuhang Zhou, Yining Ma, Xiaoxiao Wang, Yingwei Tang, Kanghao Chen, Xinyu Wang & Yan Liu. (2022) Enhanced Oral Absorption and Liver Distribution of Polymeric Nanoparticles through Traveling the Enterohepatic Circulation Pathways of Bile Acid. ACS Applied Materials & Interfaces 14:37, pages 41712-41725.
Crossref
Narjes Nasiri-Ansari, Theodoros Androutsakos, Christina-Maria Flessa, Ioannis Kyrou, Gerasimos Siasos, Harpal S. Randeva, Eva Kassi & Athanasios G. Papavassiliou. (2022) Endothelial Cell Dysfunction and Nonalcoholic Fatty Liver Disease (NAFLD): A Concise Review. Cells 11:16, pages 2511.
Crossref
Aijun Qiu, Yunyun Wang, Genlin Zhang & Hebin Wang. (2022) Natural Polysaccharide-Based Nanodrug Delivery Systems for Treatment of Diabetes. Polymers 14:15, pages 3217.
Crossref
Ji-Yuan Zhang, Xiao-Xia Liu, Jia-Yi Lin, Xiao-Yan Bao, Jian-Qing Peng, Zi-Peng Gong, Xin Luan & Yi Chen. (2022) Biomimetic engineered nanocarriers inspired by viruses for oral-drug delivery. International Journal of Pharmaceutics 624, pages 121979.
Crossref
Nicholas J. Hunt, Peter A. G. McCourt, Zdenka Kuncic, David G. Le Couteur & Victoria C. Cogger. (2022) Opportunities and Challenges for Nanotherapeutics for the Aging Population. Frontiers in Nanotechnology 4.
Crossref
Sabya Sachi Das, Sweta Kar, Sandeep Kumar Singh, P.R.P. Verma, Afzal Hussain & Sarwar Beg. 2022. Chitosan in Drug Delivery. Chitosan in Drug Delivery 23 53 .
Seyedeh Alia Moosavian, Thozhukat Sathyapalan, Tannaz Jamialahmadi & Amirhossein Sahebkar. (2021) The Emerging Role of Nanomedicine in the Management of Nonalcoholic Fatty Liver Disease: A State-of-the-Art Review. Bioinorganic Chemistry and Applications 2021, pages 1-13.
Crossref
Jung Seok Lee, Patrick Han, Rabib Chaudhury, Shihan Khan, Sean Bickerton, Michael D. McHugh, Hyun Bong Park, Alyssa L. Siefert, Gerald Rea, José M. Carballido, David A. Horwitz, Jason Criscione, Karlo Perica, Robert Samstein, Ragy Ragheb, Dongin Kim & Tarek M. Fahmy. (2021) Metabolic and immunomodulatory control of type 1 diabetes via orally delivered bile-acid-polymer nanocarriers of insulin or rapamycin. Nature Biomedical Engineering 5:9, pages 983-997.
Crossref
Yili Ding, Wutong Cui, Chamakura V. N. S. Vara Prasad & Bingyun Wang. (2021) Design and Synthesis of Lactose, Galactose and Cholic Acid Related Dual Conjugated Chitosan Derivatives as Potential Anti Liver Cancer Drug Carriers. Polymers 13:17, pages 2939.
Crossref
Xiaoyan Bao, Kang Qian & Ping Yao. (2021) Insulin- and cholic acid-loaded zein/casein–dextran nanoparticles enhance the oral absorption and hypoglycemic effect of insulin. Journal of Materials Chemistry B 9:31, pages 6234-6245.
Crossref
Melissa Jones, Daniel Walker, Corina Mihaela Ionescu, Bozica Kovacevic, Susbin Raj Wagle, Armin Mooranian, Daniel Brown & Hani Al-Salami. (2020) Microencapsulation of Coenzyme Q10 and bile acids using ionic gelation vibrational jet flow technology for oral delivery. Therapeutic Delivery 11:12, pages 791-805.
Crossref
Xiaoyan Bao, Kang Qian & Ping Yao. (2020) Oral delivery of exenatide-loaded hybrid zein nanoparticles for stable blood glucose control and β-cell repair of type 2 diabetes mice. Journal of Nanobiotechnology 18:1.
Crossref
Sanjib Sarkar, Dibyendu Das, Prachurjya Dutta, Jatin Kalita, Sawlang Borsingh Wann & Prasenjit Manna. (2020) Chitosan: A promising therapeutic agent and effective drug delivery system in managing diabetes mellitus. Carbohydrate Polymers 247, pages 116594.
Crossref
Martha Kafetzi, Stergios Pispas, Xiaoyan Bao & Ping Yao. (2020) Amphiphilic QP(DMAEMA-co-LMA)-b-POEGMA Random-Block Terpolymers as Nanocarriers for Insulin. Biomedicines 8:10, pages 392.
Crossref
Longfa Kou, Qing Yao, Hailin Zhang, Maoping Chu, Yangzom D. Bhutia, Ruijie Chen & Vadivel Ganapathy. (2020) Transporter-Targeted Nano-Sized Vehicles for Enhanced and Site-Specific Drug Delivery. Cancers 12:10, pages 2837.
Crossref
Ming Li, Qian Wang, Yong Li, Shengtian Cao, Yingjun Zhang, Zhongqing Wang, Guozhu Liu, Jing Li & Baohua Gu. (2020) Apical sodium-dependent bile acid transporter, drug target for bile acid related diseases and delivery target for prodrugs: Current and future challenges. Pharmacology & Therapeutics 212, pages 107539.
Crossref
Eliška Mašková, Kateřina Kubová, Bahijja T. Raimi-Abraham, Driton Vllasaliu, Eva Vohlídalová, Jaroslav Turánek & Josef Mašek. (2020) Hypromellose – A traditional pharmaceutical excipient with modern applications in oral and oromucosal drug delivery. Journal of Controlled Release 324, pages 695-727.
Crossref
Fei Ding, Jiawei Fu, Chuang Tao, Yanhua Yu, Xianran He, Yangguang Gao & Yongmin Zhang. (2020) Recent Advances of Chitosan and its Derivatives in Biomedical Applications. Current Medicinal Chemistry 27:18, pages 3023-3045.
Crossref
Indra Hering, Elke Eilebrecht, Michael J. Parnham, Nazende Günday-Türeli, Akif Emre Türeli, Marc Weiler, Christoph Schäfers, Martina Fenske & Matthias G. Wacker. (2020) Evaluation of potential environmental toxicity of polymeric nanomaterials and surfactants. Environmental Toxicology and Pharmacology 76, pages 103353.
Crossref
Lilong Sun, Zhicheng Le, Shuran He, Jingyan Liu, Lixin Liu, Kam W. Leong, Hai-Quan Mao, Zhijia Liu & Yongming Chen. (2020) Flash Fabrication of Orally Targeted Nanocomplexes for Improved Transport of Salmon Calcitonin across the Intestine. Molecular Pharmaceutics 17:3, pages 757-768.
Crossref
Xiankang Hu, Guoyu Yang, Sheng Chen, Suxin Luo & Jianxiang Zhang. (2020) Biomimetic and bioinspired strategies for oral drug delivery. Biomaterials Science 8:4, pages 1020-1044.
Crossref
Linxia Xiao, Jialin Xu, Qi Weng, Leilei Zhou, Mengke Wang, Miao Liu & Qingyong Li. (2020) Mechanism of a Novel Camptothecin-Deoxycholic Acid Derivate Induced Apoptosis against Human Liver Cancer HepG2 Cells and Human Colon Cancer HCT116 Cells. Recent Patents on Anti-Cancer Drug Discovery 14:4, pages 370-382.
Crossref
Chun Y. Wong, Giuseppe Luna, Jorge Martinez, Hani Al-Salami & Crispin R. Dass. (2019) Bio-nanotechnological advancement of orally administered insulin nanoparticles: Comprehensive review of experimental design for physicochemical characterization. International Journal of Pharmaceutics 572, pages 118720.
Crossref
Lilong Sun, Zhijia Liu, Houkuan Tian, Zhicheng Le, Lixin Liu, Kam W. Leong, Hai-Quan Mao & Yongming Chen. (2018) Scalable Manufacturing of Enteric Encapsulation Systems for Site-Specific Oral Insulin Delivery. Biomacromolecules 20:1, pages 528-538.
Crossref
Hongyan Su, Yan Wang, Shuo Liu, Yue Wang, Qian Liu, Guangxuan Liu & Qin Chen. (2019) Emerging transporter-targeted nanoparticulate drug delivery systems. Acta Pharmaceutica Sinica B 9:1, pages 49-58.
Crossref
Desheng Cai, Shaoyan Lou, Su Huo, Yuqin Yang, Feng Gao, Wenmin Pi, Kedian Chen, Cheng Wang, Xiaoyun Yang, Jingyi Jiao, Bing Xu, Penglong Wang & Haimin Lei. (2022) Synthesis and Biological Activity Evaluation of Podophyllotoxin- Linked Bile Acids Derivatives As Potential Anti-Liver Cancer Agents. SSRN Electronic Journal.
Crossref