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Critical Review

The challenges of oral drug delivery via nanocarriers

, &
Pages 1694-1705 | Received 17 Apr 2018, Accepted 12 Jul 2018, Published online: 03 Nov 2018

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Crossref
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Crossref
Ludivine Delon, Rachel J. Gibson, Clive A Prestidge & Benjamin Thierry. (2022) Mechanisms of uptake and transport of particulate formulations in the small intestine. Journal of Controlled Release 343, pages 584-599.
Crossref
João P. Martins, Patrícia Figueiredo, Shiqi Wang, Erika Espo, Elena Celi, Beatriz Martins, Marianna Kemell, Karina Moslova, Ermei Mäkilä, Jarno Salonen, Mauri A. Kostiainen, Christian Celia, Vincenzo Cerullo, Tapani Viitala, Bruno Sarmento, Jouni Hirvonen & Hélder A. Santos. (2022) Neonatal Fc receptor-targeted lignin-encapsulated porous silicon nanoparticles for enhanced cellular interactions and insulin permeation across the intestinal epithelium. Bioactive Materials 9, pages 299-315.
Crossref
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Crossref
Myla Lôbo de Souza, Victor de Albuquerque Wanderley Sales, Larissa Pereira Alves, Widson Michael dos Santos, Leslie Raphael de Moura Ferraz, Gustavo Siqueira de Andrade Lima, Larissa Morgana dos Santos Mendes, Larissa Araújo Rolim & Pedro José Rolim Neto. (2022) A Systematic Review of Functionalized Polymeric Nanoparticles to Improve Intestinal Permeability of Drugs and Biological Products. Current Pharmaceutical Design 28:5, pages 410-426.
Crossref
Khushboo Kourani, Poonam Jain, Aviral Kumar, Ashok Kumar Jangid, Guruprasadh Swaminathan, Varsha Reddy Durgempudi, Jedy Jose, Rithvik Reddy, Deep Pooja, Hitesh Kulhari & Lekha Dinesh Kumar. (2022) Inulin coated Mn3O4 nanocuboids coupled with RNA interference reverse intestinal tumorigenesis in Apc knockout murine colon cancer models. Nanomedicine: Nanotechnology, Biology and Medicine 40, pages 102504.
Crossref
Sonia Youhanna, Aurino M. Kemas, Lena Preiss, Yitian Zhou, Joanne X. Shen, Selgin D. Cakal, Francesco S. Paqualini, Sravan K. Goparaju, Reza Zandi Shafagh, Johan Ulrik Lind, Carl M. Sellgren & Volker M. Lauschke. (2022) Organotypic and Microphysiological Human Tissue Models for Drug Discovery and Development—Current State-of-the-Art and Future Perspectives. Pharmacological Reviews 74:1, pages 141-206.
Crossref
Negar Bidar, Majid Darroudi, Ailin Ebrahimzadeh, Mohammadreza Safdari, Miguel de la Guardia, Behzad Baradaran, Vahabodin Goodarzi, Fatemeh Oroojalian & Ahad Mokhtarzadeh. (2022) Simultaneous nanocarrier-mediated delivery of siRNAs and chemotherapeutic agents in cancer therapy and diagnosis: Recent advances. European Journal of Pharmacology 915, pages 174639.
Crossref
Y. De Anda-Flores, E. Carvajal-Millan, A.C. Campa-Mada, K.G. Martínez-Robinson, J. Lizardi-Mendoza, A. Rascón-Chu, A.L. Martínez-López & J. Tanori-Cordova. 2022. Biological Macromolecules. Biological Macromolecules 581 606 .
Yujiao Sun & Shirui Mao. 2022. Polysaccharide Nanoparticles. Polysaccharide Nanoparticles 281 311 .
Tao Sun, Chufeng Li, Xuwen Li, Haolin Song, Boyu Su, Haoyu You, Tongyu Zhang & Chen Jiang. 2020. Nanomedicine. Nanomedicine 1 106 .
Nazim Nassar, Stefan Kasapis, Suneela Pyreddy & Taghrid Istivan. 2022. Nano-Strategies for Addressing Antimicrobial Resistance. Nano-Strategies for Addressing Antimicrobial Resistance 1 74 .
Giovana Onzi, Silvia S. Guterres, Adriana R. Pohlmann & Luiza Abrahão Frank. 2022. The ADME Encyclopedia. The ADME Encyclopedia 753 766 .
Dóra Kósa, Ágota Pető, Ferenc Fenyvesi, Judit Váradi, Miklós Vecsernyés, István Budai, József Németh, Pálma Fehér, Ildikó Bácskay & Zoltán Ujhelyi. (2021) Oral Bioavailability Enhancement of Melanin Concentrating Hormone, Development and In Vitro Pharmaceutical Assessment of Novel Delivery Systems. Pharmaceutics 14:1, pages 9.
Crossref
Nina Katarina Grilc, Matej Sova & Julijana Kristl. (2021) Drug Delivery Strategies for Curcumin and Other Natural Nrf2 Modulators of Oxidative Stress-Related Diseases. Pharmaceutics 13:12, pages 2137.
Crossref
Danni Zhong, Dongxiao Zhang, Wei Chen, Jian He, Chaojie Ren, Xingcai Zhang, Na Kong, Wei Tao & Min Zhou. (2021) Orally deliverable strategy based on microalgal biomass for intestinal disease treatment. Science Advances 7:48.
Crossref
Mumuni Sumaila, Thashree Marimuthu, Pradeep Kumar & Yahya E. Choonara. (2021) Lipopolysaccharide Nanosystems for the Enhancement of Oral Bioavailability. AAPS PharmSciTech 22:7.
Crossref
Daniel Fleischmann & Achim Goepferich. (2021) General sites of nanoparticle biodistribution as a novel opportunity for nanomedicine. European Journal of Pharmaceutics and Biopharmaceutics 166, pages 44-60.
Crossref
Guiqiu Wang, Rilun Li, Benyamin Parseh & Gang Du. (2021) Prospects and challenges of anticancer agents’ delivery via chitosan-based drug carriers to combat breast cancer: a review. Carbohydrate Polymers 268, pages 118192.
Crossref
Jiulong Li, Xiang Wang, Chong Hyun Chang, Jinhong Jiang, Qi Liu, Xiangsheng Liu, Yu‐Pei Liao, Tiancong Ma, Huan Meng & Tian Xia. (2021) Nanocellulose Length Determines the Differential Cytotoxic Effects and Inflammatory Responses in Macrophages and Hepatocytes. Small 17:38.
Crossref
Yubia De Anda-Flores, Elizabeth Carvajal-Millan, Alma Campa-Mada, Jaime Lizardi-Mendoza, Agustin Rascon-Chu, Judith Tanori-Cordova & Ana Luisa Martínez-López. (2021) Polysaccharide-Based Nanoparticles for Colon-Targeted Drug Delivery Systems. Polysaccharides 2:3, pages 626-647.
Crossref
Eric Mühlberg, Mira Burtscher, Florian Umstätter, Gert Fricker, Walter Mier & Philipp Uhl. (2021) Trends in liposomal nanocarrier strategies for the oral delivery of biologics. Nanomedicine 16:20, pages 1813-1832.
Crossref
Gasper Fernandes, Abhijeet Pandey, Sanjay Kulkarni, Sadhana P. Mutalik, Ajinkya Nitin Nikam, Raviraja N. Seetharam, Smita S. Kulkarni & Srinivas Mutalik. (2021) Supramolecular dendrimers based novel platforms for effective oral delivery of therapeutic moieties. Journal of Drug Delivery Science and Technology 64, pages 102647.
Crossref
Tamer H. Hassan, Shymaa S. Salman, Mahmoud M. Elkhoudary & Shadeed. Gad. (2021) Refinement of Simvastatin and Nifedipine combined delivery through multivariate conceptualization and optimization of the nanostructured lipid carriers. Journal of Drug Delivery Science and Technology 64, pages 102570.
Crossref
Yingxue Deng, Rui Huang, Songyin Huang & Menghua Xiong. (2021) Nanoparticles Enable Efficient Delivery of Antimicrobial Peptides for the Treatment of Deep Infections. BIO Integration 2:2, pages 50-56.
Crossref
Kangkang Ying, Bingjun Bai, Xing Gao, Yuzi Xu, Hangxiang Wang & Binbin Xie. (2021) Orally Administrable Therapeutic Nanoparticles for the Treatment of Colorectal Cancer. Frontiers in Bioengineering and Biotechnology 9.
Crossref
Jiaqi Li, Yifei Li, Jinfeng Zhong, Yonghua Wang, Xiong Liu & Xiaoli Qin. (2021) Effect of cellulose nanocrystals on the formation and stability of oil-in-water emulsion formed by octenyl succinic anhydride starch. LWT, pages 112214.
Crossref
Asmaa Elzayat, Inés Adam-Cervera, Olaia Álvarez-Bermúdez & Rafael Muñoz-Espí. (2021) Nanoemulsions for synthesis of biomedical nanocarriers. Colloids and Surfaces B: Biointerfaces 203, pages 111764.
Crossref
Wanfa Dong, Dan Liu, Tingting Zhang, Qi You, Fengjie Huang & Jie Wu. (2021) Oral delivery of staphylococcal nuclease ameliorates DSS induced ulcerative colitis in mice via degrading intestinal neutrophil extracellular traps. Ecotoxicology and Environmental Safety 215, pages 112161.
Crossref
Jacopo Oieni, Andrea Lolli, Domenico D'Atri, Nicole Kops, Avner Yayon, Gerjo J.V.M. van Osch & Marcelle Machluf. (2021) Nano-ghosts: Novel biomimetic nano-vesicles for the delivery of antisense oligonucleotides. Journal of Controlled Release 333, pages 28-40.
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Dianxiong Zou, Meenakshi Arora, Raghu Ganugula, Mokshada Kumar, Erin M. Scott, Dhaval Shah & M.N.V. Ravi Kumar. (2021) Nanoparticles that do not compete with endogenous ligands – Molecular characterization in vitro, acute safety in canine, and interspecies pharmacokinetics modeling to humans. Journal of Controlled Release 332, pages 64-73.
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Sylwia Łukasiewicz. (2021) Development of a New Polymeric Nanocarrier Dedicated to Controlled Clozapine Delivery at the Dopamine D2-Serotonin 5-HT1A Heteromers. Polymers 13:7, pages 1000.
Crossref
Jiao Liu, Ping Leng & Yujun Liu. (2020) Oral drug delivery with nanoparticles into the gastrointestinal mucosa. Fundamental & Clinical Pharmacology 35:1, pages 86-96.
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Asadullah Madni, Sadia Rehman, Humaira Sultan, Muhammad Muzamil Khan, Faiz Ahmad, M. Rafi Raza, Nadia Rai & Farzana Parveen. (2020) Mechanistic Approaches of Internalization, Subcellular Trafficking, and Cytotoxicity of Nanoparticles for Targeting the Small Intestine. AAPS PharmSciTech 22:1.
Crossref
Jonathan Wang, Deborah Chin, Christopher Poon, Valeria Mancino, Jessica Pham, Hui Li, Pei-Yin Ho, Kenneth R. Hallows & Eun Ji Chung. (2021) Oral delivery of metformin by chitosan nanoparticles for polycystic kidney disease. Journal of Controlled Release 329, pages 1198-1209.
Crossref
Rita C. Bicho, Augusto M.R. Faustino, Fátima Carvalho, Amadeu M.V.M. Soares, Janeck J. Scott-Fordsmand & Mónica J.B. Amorim. (2021) Embryotoxicity of silver nanomaterials (Ag NM300k) in the soil invertebrate Enchytraeus crypticus – Functional assay detects Ca channels shutdown. NanoImpact 21, pages 100300.
Crossref
Rohan S.J. Ingrole, Erkan Azizoglu, Maria Dul, James C. Birchall, Harvinder S. Gill & Mark R. Prausnitz. (2021) Trends of microneedle technology in the scientific literature, patents, clinical trials and internet activity. Biomaterials 267, pages 120491.
Crossref
Nitin Sharma, Ritu Karwasra & Gaurav Kumar Jain. 2021. Advanced Drug Delivery Systems in the Management of Cancer. Advanced Drug Delivery Systems in the Management of Cancer 259 266 .
Shivakumar Mahadeva Lal, Ashwin Kamath, Amrita Parida & Smita Shenoy. 2021. Nano-Pharmacokinetics and Theranostics. Nano-Pharmacokinetics and Theranostics 171 192 .
Deviprasad Sahoo, Ravi Bandaru, Sangram Keshari Samal, Ramakanta Naik, Pramod Kumar, Prashant Kesharwani & Rambabu Dandela. 2021. Theory and Applications of Nonparenteral Nanomedicines. Theory and Applications of Nonparenteral Nanomedicines 181 207 .
M. D. Figueroa-Pizano & E. Carvajal-Millan. 2021. Ionically Gelled Biopolysaccharide Based Systems in Drug Delivery. Ionically Gelled Biopolysaccharide Based Systems in Drug Delivery 135 160 .
Siew-Wai Pang, Michiele Lee-Kiun Soon, Kamyar Shameli, Pushpamalar Janarthanan & Sin-Yeang Teow. 2021. Nanotechnology in Medicine. Nanotechnology in Medicine 199 224 .
Giovana Onzi, Silvia S. Guterres, Adriana R. Pohlmann & Luiza Abrahão Frank. 2021. The ADME Encyclopedia. The ADME Encyclopedia 1 13 .
Cornelia Baeckmann, Hanspeter Kählig, Mika Lindén & Freddy Kleitz. (2020) Irreversible Adsorption of Serum Proteins onto Nanoparticles. Particle & Particle Systems Characterization 38:1, pages 2000273.
Crossref
Eman Salah, Mahmoud M. Abouelfetouh, Yuanhu Pan, Dongmei Chen & Shuyu Xie. (2020) Solid lipid nanoparticles for enhanced oral absorption: A review. Colloids and Surfaces B: Biointerfaces 196, pages 111305.
Crossref
Juliana Santos Rosa Viegas, Fabíola Garcia Praça, Marcelo Kravicz & Maria Vitoria Lopes Badra Bentley. (2020) Therapeutic applications and delivery systems for triptolide. Drug Delivery and Translational Research 10:6, pages 1584-1600.
Crossref
Amandeep Singh, Kirandeep Kaur, Uttam Kumar Mandal & Raj Kumar Narang. (2020) Nanoparticles as Budding Trends in Colon Drug Delivery for the Management of Ulcerative Colitis. Current Nanomedicine 10:3, pages 225-247.
Crossref
Feiyang Deng & You Han Bae. (2020) Bile acid transporter-mediated oral drug delivery. Journal of Controlled Release 327, pages 100-116.
Crossref
Santwana Padhi, Amit Kumar Nayak & Anindita Behera. (2020) Type II diabetes mellitus: a review on recent drug based therapeutics. Biomedicine & Pharmacotherapy 131, pages 110708.
Crossref
Brabu Balusamy, Asli Celebioglu, Anitha Senthamizhan & Tamer Uyar. (2020) Progress in the design and development of “fast-dissolving” electrospun nanofibers based drug delivery systems - A systematic review. Journal of Controlled Release 326, pages 482-509.
Crossref
Arturo Sánchez, Susana P. Mejía & Jahir Orozco. (2020) Recent Advances in Polymeric Nanoparticle-Encapsulated Drugs against Intracellular Infections. Molecules 25:16, pages 3760.
Crossref
Stephanie J. Franks, Kate Firipis, Rita Ferreira, Katherine M. Hannan, Richard J. Williams, Ross D. Hannan & David R. Nisbet. (2020) Harnessing the self-assembly of peptides for the targeted delivery of anti-cancer agents. Materials Horizons 7:8, pages 1996-2010.
Crossref
Ruichen Zhao, Zhiguo Lu, Jun Yang, Liqun Zhang, Yan Li & Xin Zhang. (2020) Drug Delivery System in the Treatment of Diabetes Mellitus. Frontiers in Bioengineering and Biotechnology 8.
Crossref
Pasakorn Jutakridsada, Nutsupa Pimsawat, Mika Sillanpää & Khanita Kamwilaisak. (2020) Olive oil stability in Pickering emulsion preparation from eucalyptus pulp and its rheology behaviour. Cellulose 27:11, pages 6189-6203.
Crossref
Marie-Luise Frey, Johanna Simon, Maximilian Brückner, Volker Mailänder, Svenja Morsbach & Katharina Landfester. (2020) Bio-orthogonal triazolinedione (TAD) crosslinked protein nanocapsules affect protein adsorption and cell interaction. Polymer Chemistry 11:23, pages 3821-3830.
Crossref
Pataranapa Nimtrakul, Desmond B. Williams, Waree Tiyaboonchai & Clive A. Prestidge. (2020) Copolymeric Micelles Overcome the Oral Delivery Challenges of Amphotericin B. Pharmaceuticals 13:6, pages 121.
Crossref
Xuejing Cui, Lin Bao, Xiaoyu Wang & Chunying Chen. (2020) The Nano–Intestine Interaction: Understanding the Location‐Oriented Effects of Engineered Nanomaterials in the Intestine. Small 16:21.
Crossref
Susan Hua. (2020) Advances in Oral Drug Delivery for Regional Targeting in the Gastrointestinal Tract - Influence of Physiological, Pathophysiological and Pharmaceutical Factors. Frontiers in Pharmacology 11.
Crossref
Zhenhua Hu, Sara Nizzero, Shreya Goel, Louis E. HinkleXiaoyan WuChao LiMauro FerrariHaifa Shen. (2020) Molecular targeting of FATP4 transporter for oral delivery of therapeutic peptide. Science Advances 6:14.
Crossref
Ahmed A. H. Abdellatif, Mohamed A. Ibrahim, Mohammed A. Amin, Hamzah Maswadeh, Muhammed N. Alwehaibi, Sultan N. Al-Harbi, Zayed A. Alharbi, Hamdoon A. Mohammed, Ahmed B. M. Mehany & Imran Saleem. (2020) Cetuximab Conjugated with Octreotide and Entrapped Calcium Alginate-beads for Targeting Somatostatin Receptors. Scientific Reports 10:1.
Crossref
Prarthana Rewatkar, Tushar Kumeria & Amirali Popat. 2020. Nanotechnology for Oral Drug Delivery. Nanotechnology for Oral Drug Delivery 143 176 .
João Pedro Martins & Hélder A. Santos. 2020. Nanotechnology for Oral Drug Delivery. Nanotechnology for Oral Drug Delivery 3 6 .
Radhika Narayanaswamy, Sara Aly Attia & Vladimir P. Torchilin. 2020. Systemic Delivery Technologies in Anti-Aging Medicine: Methods and Applications. Systemic Delivery Technologies in Anti-Aging Medicine: Methods and Applications 447 475 .
Jin-Oh Jeong, Jong-Soek Park, Eui Jin Kim, Sung-In Jeong, Jae Young Lee & Youn-Mook Lim. (2019) Preparation of Radiation Cross-Linked Poly(Acrylic Acid) Hydrogel Containing Metronidazole with Enhanced Antibacterial Activity. International Journal of Molecular Sciences 21:1, pages 187.
Crossref
Vincenzo Zaccaria, Emanuele Ugo Garzarella, Carmen Di Giovanni, Fabio Galeotti, Lucia Gisone, Davide Campoccia, Nicola Volpi, Carla Renata Arciola & Maria Daglia. (2019) Multi Dynamic Extraction: An Innovative Method to Obtain a Standardized Chemically and Biologically Reproducible Polyphenol Extract from Poplar-Type Propolis to Be Used for Its Anti-Infective Properties. Materials 12:22, pages 3746.
Crossref
Marcin Makowski, Ítala C. Silva, Constança Pais do Amaral, Sónia Gonçalves & Nuno C. Santos. (2019) Advances in Lipid and Metal Nanoparticles for Antimicrobial Peptide Delivery. Pharmaceutics 11:11, pages 588.
Crossref
A K M Nawshad Hossian, Gerardo G Mackenzie & George Mattheolabakis. (2019) miRNAs in gastrointestinal diseases: can we effectively deliver RNA-based therapeutics orally?. Nanomedicine 14:21, pages 2873-2889.
Crossref
Dianxiong Zou, Raghu Ganugula, Meenakshi Arora, Mary B. Nabity, David Sheikh-Hamad & M. N. V. Ravi Kumar. (2019) Oral delivery of nanoparticle urolithin A normalizes cellular stress and improves survival in mouse model of cisplatin-induced AKI. American Journal of Physiology-Renal Physiology 317:5, pages F1255-F1264.
Crossref
Kumaresan S.Radheshyam Rama Pawar, Bhavesh D. Kevadiya & Hari C. Bajaj. (2019) Synthesis of Saponite Based Nanocomposites to Improve the Controlled Oral Drug Release of Model Drug Quinine Hydrochloride Dihydrate. Pharmaceuticals 12:3, pages 105.
Crossref