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Drug Delivery Volume 28, 2021 - Issue 1
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Research Article

Oral gel loaded with penciclovir–lavender oil nanoemulsion to enhance bioavailability and alleviate pain associated with herpes labialis

Khaled M. Hosnya Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia;b Center of Excellence for Drug Research and Pharmaceutical Industries, King Abdulaziz University, Jeddah, Saudi ArabiaCorrespondence[email protected] [email protected]
ORCID Iconhttps://orcid.org/0000-0002-4904-1378
ORCID Icon,
Amal M. Sindic Oral Diagnostic Sciences Department, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi ArabiaORCID Iconhttps://orcid.org/0000-0002-5286-1756
ORCID Icon,
Hala M. Alkhalidid Department of Clinical Pharmacy, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia
,
Mallesh Kurakulae Department of Biomedical Engineering, The Herff College of Engineering, Memphis, TN, USA
,
Nabil K. Alruwailif Department of Pharmaceutics, Faculty of Pharmacy, Jouf University, Sakaka, Saudi ArabiaORCID Iconhttps://orcid.org/0000-0003-2358-4259
ORCID Icon,
Nabil A. Alhakamya Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia;b Center of Excellence for Drug Research and Pharmaceutical Industries, King Abdulaziz University, Jeddah, Saudi ArabiaORCID Iconhttps://orcid.org/0000-0002-3826-1519
ORCID Icon,
Walaa A. Abualsununa Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia
,
Rana B. Bakhaidara Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia
,
Rahaf H. Bahmdana Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia
,
Waleed Y. Rizga Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia;b Center of Excellence for Drug Research and Pharmaceutical Industries, King Abdulaziz University, Jeddah, Saudi ArabiaORCID Iconhttps://orcid.org/0000-0002-3088-4084
ORCID Icon,
Sarah A. Alic Oral Diagnostic Sciences Department, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia
,
Wesam H. Abdulaalg Department of Biochemistry, Faculty of Science, Cancer and Mutagenesis Unit, King Fahd Center for Medical Research, King Abdulaziz University, Jeddah, Saudi Arabia
,
Majed S. Nassarh Life Science and Environment Research Institute, King Abdulaziz City for Science and Technology (KACST), Riyadh,Saudi Arabia
,
Mohammed S. Alsuabeylh Life Science and Environment Research Institute, King Abdulaziz City for Science and Technology (KACST), Riyadh,Saudi Arabia
,
Adel F. Alghaithi Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia
&
Sultan Alshehrii Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia;j Department of Pharmaceutical Sciences, College of Pharmacy, Almaarefa University, Riyadh, Saudi Arabia
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Pages 1043-1054 | Received 16 Apr 2021, Accepted 10 May 2021, Published online: 01 Jun 2021

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Muhammad Khalid Khan, Barkat Ali Khan, Bushra Uzair, Shah Iram Niaz, Haroon Khan, Khaled Mohamed Hosny & Farid Menaa. (2021) RETRACTED ARTCLE: Development of Chitosan-Based Nanoemulsion Gel Containing Microbial Secondary Metabolite with Effective Antifungal Activity: In vitro and in vivo Characterizations. International Journal of Nanomedicine 16, pages 8203-8219.
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Anjie Feng, Tiantian Si, Baoxiang Du, Qihui Sun, Yong Yang & Rong Rong. (2024) Antiviral potential of essential oils and their plant sources, delivery methods, and drug development strategies with special focus on their mechanisms: a comprehensive review. Phytochemistry Reviews.
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Karolina Zyburtowicz, Paulina Bednarczyk, Anna Nowak, Anna Muzykiewicz-Szymańska, Łukasz Kucharski, Aneta Wesołowska & Paula Ossowicz-Rupniewska. (2024) Medicinal Anti-Inflammatory Patch Loaded with Lavender Essential Oil. International Journal of Molecular Sciences 25:11, pages 6171.
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Dorin Ioan Cocoș, Olimpia Dumitriu Buzia, Alin Laurențiu Tatu, Monica Dinu, Lawrence Chukwudi Nwabudike, Claudia Simona Stefan, Kamel Earar & Carmen Galea. (2024) Challenges in Optimizing Nanoplatforms Used for Local and Systemic Delivery in the Oral Cavity. Pharmaceutics 16:5, pages 626.
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Faeze Fahimnia, Mehran Nemattalab & Zahra Hesari. (2024) Development and characterization of a topical gel, containing lavender (Lavandula angustifolia) oil loaded solid lipid nanoparticles. BMC Complementary Medicine and Therapies 24:1.
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Dominika Žigrayová, Veronika Mikušová & Peter Mikuš. (2023) Advances in Antiviral Delivery Systems and Chitosan-Based Polymeric and Nanoparticulate Antivirals and Antiviral Carriers. Viruses 15:3, pages 647.
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Abdelsamed I. Elshamy, Walaa A. El-Kashak, Rehab F. Taher, Mai M. Elghonemy, Rania F. Ahmed, Tarik A. Mohamed, Ahmed F. Essa, Tamer I. M. Ragab, Mohamed F. Abdelhameed, Abd El-Nasser G. El-Gendy, Mahmoud I. Nassar, Ahmed M. Abd-ELGawad, Abdel Razik H. Farrag, Howaida I. Abd-Alla & Mohamed-Elamir F. Hegazy. 2023. Current Trends in Green Nano-emulsions. Current Trends in Green Nano-emulsions 263 297 .
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Hossam H. Tayeb, Raed Felimban, Sarah Almaghrabi & Nojod Hasaballah. (2021) Nanoemulsions: Formulation, characterization, biological fate, and potential role against COVID-19 and other viral outbreaks. Colloid and Interface Science Communications 45, pages 100533.
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