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Drug Delivery Volume 28, 2021 - Issue 1
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Research Article

Eplerenone nanocrystals engineered by controlled crystallization for enhanced oral bioavailability

Muhammad Ayub Khana Riphah Institute of Pharmaceutical Sciences, Riphah International University, Islamabad, PakistanView further author information
,
Muhammad Mohsin Ansaria Riphah Institute of Pharmaceutical Sciences, Riphah International University, Islamabad, PakistanView further author information
,
Sadia Tabassam Arifa Riphah Institute of Pharmaceutical Sciences, Riphah International University, Islamabad, PakistanView further author information
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Abida Razab Nanomedicine Research Laboratory, National Institute of Lasers and Optronics (NILOP), PIEAS, Islamabad, PakistanORCID Iconhttps://orcid.org/0000-0002-4414-1070View further author information
ORCID Icon,
Ho-Ik Choic College of Pharmacy, Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan, Republic of KoreaView further author information
,
Chang-Wan Limc College of Pharmacy, Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan, Republic of KoreaView further author information
,
Ha-Yeon Nohc College of Pharmacy, Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan, Republic of KoreaView further author information
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Jin-Su Nohc College of Pharmacy, Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan, Republic of KoreaView further author information
,
Salman Akramd Laboratory for the Study of Rheology and the Adhesion of Medical Adhesives, IPREM, University of Pau and Pays de l'Adour, Pau, FranceView further author information
,
Hafiz Awais Nawaze Institute of Pharmaceutical Sciences, University of Veterinary and Animal Sciences, Lahore, PakistanView further author information
,
Muhammad Ammadf Drug Testing Laboratory, Lahore, PakistanView further author information
,
Abir Abdullah Alamrog Department of Biochemistry, College of Science, King Saud University, Riyadh, Saudi ArabiaView further author information
,
Amani Ahmed Alghamdig Department of Biochemistry, College of Science, King Saud University, Riyadh, Saudi ArabiaView further author information
,
Jin-Ki Kimc College of Pharmacy, Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan, Republic of KoreaCorrespondence[email protected]
View further author information
&
Alam Zeba Riphah Institute of Pharmaceutical Sciences, Riphah International University, Islamabad, PakistanCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-3753-034XView further author information
ORCID Icon show all
Pages 2510-2524 | Received 07 Sep 2021, Accepted 01 Nov 2021, Published online: 29 Nov 2021

Citations (9)

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Shirleen Miriam Marques & Lalit Kumar. (2023) Factors affecting the preparation of nanocrystals: characterization, surface modifications and toxicity aspects. Expert Opinion on Drug Delivery 20:7, pages 871-894.
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Ghada E. Yassin & Maha K. A. Khalifa. (2022) Development of eplerenone nano sono-crystals using factorial design: enhanced solubility and dissolution rate via anti solvent crystallization technique. Drug Development and Industrial Pharmacy 48:12, pages 683-693.
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Christian Höcht, Miguel A Allo, Ariel Héctor Polizio, Marcela A Morettón, Andrea Carranza, Diego A Chiappetta & Marcelo Roberto Choi. (2022) New and developing pharmacotherapies for hypertension. Expert Review of Cardiovascular Therapy 20:8, pages 647-666.
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Sidra Saeed, Usama Sarwar, Masoom Yasinzai & Abida Raza. (2023) Glycol chitosan amphiphile nanotheranostic system for ultrasound-mediated localized release and biodistribution of doxorubicin. Journal of Nanoparticle Research 25:9.
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Sadia Tabassam Arif, Muhammad Ayub Khan, Shahiq uz Zaman, Hafiz Shoaib Sarwar, Abida Raza, Muhammad Sarfraz, Yousef A. Bin Jardan, Muhammad Umair Amin & Muhammad Farhan Sohail. (2023) Enhanced Antidepressant Activity of Nanostructured Lipid Carriers Containing Levosulpiride in Behavioral Despair Tests in Mice. Pharmaceuticals 16:9, pages 1220.
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Muhammad Mohsin Ansari, Dang-Khoa Vo, Ho-Ik Choi, Jeong-Su Ryu, Yumi Bae, Nadeem Irfan Bukhari, Alam Zeb, Jin-Ki Kim & Han-Joo Maeng. (2023) Formulation and Evaluation of a Self-Microemulsifying Drug Delivery System of Raloxifene with Improved Solubility and Oral Bioavailability. Pharmaceutics 15:8, pages 2073.
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Fang Wang, Zhen Li, Xin-yue Gan, Xiao-ling Lu, Bing-hua Jiao & Min-hua Shen. (2023) Quality by design driven development and evaluation of thermosensitive hydrogel loaded with IgY and LL37-SLNs to combat experimental periodontitis. European Journal of Pharmaceutical Sciences 185, pages 106444.
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Sadia Tabassam Arif, Shahiq uz Zaman, Muhammad Ayub Khan, Tanveer A. Tabish, Muhammad Farhan Sohail, Rabia Arshad, Jin-Ki Kim & Alam Zeb. (2022) Augmented Oral Bioavailability and Prokinetic Activity of Levosulpiride Delivered in Nanostructured Lipid Carriers. Pharmaceutics 14:11, pages 2347.
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Jie Zhang, Minzhuo Liu & Zhihong Zeng. (2022) The antisolvent coprecipitation method for enhanced bioavailability of poorly water-soluble drugs. International Journal of Pharmaceutics 626, pages 122043.
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