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Artificial Cells, Blood Substitutes, and Biotechnology Volume 36, 2008 - Issue 4
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Original

Convection and Hemoglobin-Based Oxygen Carrier Enhanced Oxygen Transport in a Hepatic Hollow Fiber Bioreactor

Jesse P. Sullivan Department of Chemical & Biomolecular Engineering, University of Notre Dame, Notre Dame, IN, USA
,
David R. Harris Department of Chemical & Biomolecular Engineering, The Ohio State University, Columbus, OH, USA
&
Andre F. Palmer Department of Chemical & Biomolecular Engineering, The Ohio State University, Columbus, OH, USA
Pages 386-402 | Published online: 11 Jul 2009

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M. W. Naing & D. J. Williams. (2011) Three-dimensional culture and bioreactors for cellular therapies. Cytotherapy 13:4, pages 391-399.
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Articles from other publishers (16)

Sofia Mohseni, Ali Baradar Khoshfetrat, Reza Rahbarghazi, Shahla Khodabakhshaghdam & Leila Shafiei Kaleybar. (2023) Influence of shear force on ex vivo expansion of hematopoietic model cells in a stirred tank bioreactor. Journal of Biological Engineering 17:1.
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Shahla Khodabakhshaghdam, Ali Baradar Khoshfetrat & Reza Rahbarghazi. (2021) Alginate-chitosan core-shell microcapsule cultures of hepatic cells in a small scale stirred bioreactor: impact of shear forces and microcapsule core composition. Journal of Biological Engineering 15:1.
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Nazely Diban & Dimitrios Stamatialis. (2014) Polymeric hollow fiber membranes for bioartificial organs and tissue engineering applications. Journal of Chemical Technology & Biotechnology 89:5, pages 633-643.
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Anwar A. Palakkan, David C. Hay, Anil K. PR, Kumary TV & James A. Ross. (2013) Liver tissue engineering and cell sources: issues and challenges. Liver International 33:5, pages 666-676.
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Gengbei Shi & Robin N. Coger. (2013) Use of perfluorocarbons to enhance the performance of perfused three‐dimensional hepatic cultures. Biotechnology Progress 29:3, pages 718-726.
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Kevin Montagne, Hongyun Huang, Keikou Ohara, Kunio Matsumoto, Atsushi Mizuno, Katsuji Ohta & Yasuyuki Sakai. (2011) Use of liposome encapsulated hemoglobin as an oxygen carrier for fetal and adult rat liver cell culture. Journal of Bioscience and Bioengineering 112:5, pages 485-490.
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Justin Dubois, Luc Tremblay, Martin Lepage & Patrick Vermette. (2011) Flow dynamics within a bioreactor for tissue engineering by residence time distribution analysis combined with fluorescence and magnetic resonance imaging to investigate forced permeability and apparent diffusion coefficient in a perfusion cell culture chamber. Biotechnology and Bioengineering 108:10, pages 2488-2498.
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Michael Maringka, Shibashish Giri, Karen Nieber, Ali Acikgöz & Augustinus Bader. (2011) Biotransformation of diazepam in a clinically relevant flat membrane bioreactor model using primary porcine hepatocytes. Fundamental & Clinical Pharmacology 25:3, pages 343-353.
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R.J. Shipley, A.J. Davidson, K. Chan, J.B. Chaudhuri, S.L Waters & M.J. Ellis. (2011) A strategy to determine operating parameters in tissue engineering hollow fiber bioreactors. Biotechnology and Bioengineering 108:6, pages 1450-1461.
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Yi-Tao Ding & Xiao-Lei Shi. (2010) Bioartificial liver devices: Perspectives on the state of the art. Frontiers of Medicine 5:1, pages 15-19.
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Sharon I. Gundersen, Guo Chen, Heather M. Powell & Andre F. Palmer. (2010) Hemoglobin regulates the metabolic and synthetic function of rat insulinoma cells cultured in a hollow fiber bioreactor. Biotechnology and Bioengineering 107:3, pages 582-592.
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Guo ChenAndre F. Palmer. (2010) Hemoglobin Regulates the Metabolic, Synthetic, Detoxification, and Biotransformation Functions of Hepatoma Cells Cultured in a Hollow Fiber Bioreactor. Tissue Engineering Part A 16:10, pages 3231-3240.
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Guo Chen & Andre F. Palmer. (2009) Mixtures of hemoglobin‐based oxygen carriers and perfluorocarbons exhibit a synergistic effect in oxygenating hepatic hollow fiber bioreactors. Biotechnology and Bioengineering 105:3, pages 534-542.
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Michael Maringka, Shibashish Giri & Augustinus Bader. (2010) Preclinical characterization of primary porcine hepatocytes in a clinically relevant flat membrane bioreactor. Biomaterials 31:1, pages 156-172.
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Martin Nieuwoudt, Scholtz Wiggett, Susan Malfeld & Schalk W. van der Merwe. (2009) Imaging glucose metabolism in perfluorocarbon-perfused hepatocyte bioreactors using positron emission tomography. Journal of Artificial Organs 12:4, pages 247-257.
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Xue-Hui Chu, Xiao-Lei Shi, Zhang-Qi Feng, Jin-Yang Gu, Hai-Yun Xu, Yue Zhang, Zhong-Ze Gu & Yi-Tao Ding. (2009) In vitro evaluation of a multi-layer radial-flow bioreactor based on galactosylated chitosan nanofiber scaffolds. Biomaterials 30:27, pages 4533-4538.
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