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Journal of Receptors and Signal Transduction Volume 28, 2008 - Issue 3

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Does Structural Commonality of Metal Complex Formation by PAC-1 (anticancer), DHBNH (anti-HIV), AHL (autoinducer), and UCS1025A (anticancer) Denote Mechanistic Similarity? Signal Transduction and Medical Aspects

PETER KOVACIC Department of Chemistry, San Diego State University, San Diego, California, USA

Pages 141-152 | Published online: 10 Oct 2008

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https://doi.org/10.1080/10799890802084077

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Leyla Yurttaş, Ömer Öztürk & Zerrin Cantürk. (2019) New Procaspase Activating Compound (PAC-1) Like Molecules as Potent Antitumoral Agents Against Lung Cancer. Letters in Drug Design & Discovery 16:6, pages 645-655.
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Peter Kovacic & Ratnasamy Somanathan. 2012. Cell Signaling & Molecular Targets in Cancer. Cell Signaling & Molecular Targets in Cancer 273 297 .

Xing Fan, Feng-Hua Zhang, Rasha I. Al-Safi, Li-Fan Zeng, Yumna Shabaik, Bikash Debnath, Tino W. Sanchez, Srinivas Odde, Nouri Neamati & Ya-Qiu Long. (2011) Design of HIV-1 integrase inhibitors targeting the catalytic domain as well as its interaction with LEDGF/p75: A scaffold hopping approach using salicylate and catechol groups. Bioorganic & Medicinal Chemistry 19:16, pages 4935-4952.
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Hua-Poo Su, Youwei Yan, G. Sridhar Prasad, Robert F. Smith, Christopher L. Daniels, Pravien D. Abeywickrema, John C. Reid, H. Marie Loughran, Maria Kornienko, Sujata Sharma, Jay A. Grobler, Bei Xu, Vinod Sardana, Timothy J. Allison, Peter D. Williams, Paul L. Darke, Daria J. Hazuda & Sanjeev Munshi. (2010) Structural Basis for the Inhibition of RNase H Activity of HIV-1 Reverse Transcriptase by RNase H Active Site-Directed Inhibitors. Journal of Virology 84:15, pages 7625-7633.
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Lei Ren, Kaishun Bi, Ping Gong, Weiming Cheng, Zhen Song, Lina Fang & Xiaohui Chen. (2008) Characterization of the in vivo and in vitro metabolic profile of PAC-1 using liquid chromatography–mass spectrometry. Journal of Chromatography B 876:1, pages 47-53.
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