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Journal of Receptors and Signal Transduction Volume 28, 2008 - Issue 4
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Research Article

TGF-β1/Smad7 Signaling Stimulates Renal Tubulointerstitial Fibrosis Induced by AAI

YANYING WANG Laboratory of Pharmacology of Chinese Veterinary Medicine, Department of Animal Science and Technology, Beijing University of Agriculture, Beijing, China; Beijing Municipal Key Laboratory of Veterinary (Traditional Chinese Medicine), Department of Animal Science and Technology, Beijing University of Agriculture, Beijing, China
,
ZHONGWEN ZHANG Laboratory of Pharmacology of Chinese Veterinary Medicine, Department of Animal Science and Technology, Beijing University of Agriculture, Beijing, China
,
HONG SHEN Laboratory of Pharmacology of Chinese Veterinary Medicine, Department of Animal Science and Technology, Beijing University of Agriculture, Beijing, China
,
YAN LU Laboratory of Pharmacology of Chinese Veterinary Medicine, Department of Animal Science and Technology, Beijing University of Agriculture, Beijing, China
,
HUANRONG LI Laboratory of Pharmacology of Chinese Veterinary Medicine, Department of Animal Science and Technology, Beijing University of Agriculture, Beijing, China
,
XIAOMING REN Laboratory of Pharmacology of Chinese Veterinary Medicine, Department of Animal Science and Technology, Beijing University of Agriculture, Beijing, China
&
GUOJUAN WU Laboratory of Pharmacology of Chinese Veterinary Medicine, Department of Animal Science and Technology, Beijing University of Agriculture, Beijing, China; Beijing Municipal Key Laboratory of Veterinary (Traditional Chinese Medicine), Department of Animal Science and Technology, Beijing University of Agriculture, Beijing, China
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Pages 413-428 | Published online: 10 Oct 2008

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Xi-Lin Xu, Lin-Jiang Yang & Jian-Guo Jiang. (2016) Renal toxic ingredients and their toxicology from traditional Chinese medicine. Expert Opinion on Drug Metabolism & Toxicology 12:2, pages 149-159.
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Yahui Tian, Fangfang Liao, Guoying Wu, Di Chang, Yaohui Yang, Xiaokai Dong, Zhongwen Zhang, Yu Zhang & Guojuan Wu. (2015) Ubiquitination and regulation of Smad7 in the TGF-β1/Smad signaling of aristolochic acid nephropathy. Toxicology Mechanisms and Methods 25:8, pages 645-652.
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Yahui Tian, Yaohui Yang, Lei Gao, Haijiao Zhao, Xiaolan Peng, Zhongwen Zhang & Guojuan Wu. (2014) Expression of histone deacetylase-1 and p300 in aristolochic acid nephropathy models. Toxicology Mechanisms and Methods 24:6, pages 377-384.
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Tian-Biao Zhou & Yuan-Han Qin. (2012) The signaling pathways of LMX1B and its role in glomerulosclerosis. Journal of Receptors and Signal Transduction 32:6, pages 285-289.
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Articles from other publishers (14)

Jia-Feng Chang, Chih-Yu Hsieh, Kuo-Cheng Lu, Yue-Wen Chen, Shih-Shin Liang, Chih-Cheng Lin, Chi-Feng Hung, Jian-Chiun Liou & Mai-Szu Wu. (2020) Therapeutic Targeting of Aristolochic Acid Induced Uremic Toxin Retention, SMAD 2/3 and JNK/ERK Pathways in Tubulointerstitial Fibrosis: Nephroprotective Role of Propolis in Chronic Kidney Disease. Toxins 12:6, pages 364.
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Sharad Kholia, Maria Beatriz Herrera Sanchez, Massimo Cedrino, Elli Papadimitriou, Marta Tapparo, Maria Chiara Deregibus, Stefania Bruno, Federica Antico, Maria Felice Brizzi, Peter J. Quesenberry & Giovanni Camussi. (2020) Mesenchymal Stem Cell Derived Extracellular Vesicles Ameliorate Kidney Injury in Aristolochic Acid Nephropathy. Frontiers in Cell and Developmental Biology 8.
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Min Yu, Yu-lin Man, Meng-hua Chen, Li-hua Wu, Yi Zhou, Xiao-ling Zhou, Na Chen, Rui Ma & Li-na Sun. (2019) Hirsutella sinensis inhibits NLRP3 inflammasome activation to block aristolochic acid-induced renal tubular epithelial cell transdifferentiation. Human Cell 33:1, pages 79-87.
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Chi-Kong Chan, Yushuo Liu, Nikola Pavlović & Wan Chan. (2019) Aristolochic Acids: Newly Identified Exposure Pathways of this Class of Environmental and Food-Borne Contaminants and its Potential Link to Chronic Kidney Diseases. Toxics 7:1, pages 14.
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Sharad Kholia, Maria Beatriz Herrera Sanchez, Massimo Cedrino, Elli Papadimitriou, Marta Tapparo, Maria Chiara Deregibus, Maria Felice Brizzi, Ciro Tetta & Giovanni Camussi. (2018) Human Liver Stem Cell-Derived Extracellular Vesicles Prevent Aristolochic Acid-Induced Kidney Fibrosis. Frontiers in Immunology 9.
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V. Bunel, F. Souard, M.-H. Antoine, C. Stévigny & J.L. Nortier. 2018. Comprehensive Toxicology. Comprehensive Toxicology 340 379 .
Inès Jadot, Anne-Emilie Declèves, Joëlle Nortier & Nathalie Caron. (2017) An Integrated View of Aristolochic Acid Nephropathy: Update of the Literature. International Journal of Molecular Sciences 18:2, pages 297.
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LEI WANG, HUI CHEN, XIU-HENG LIU, ZHI-YUAN CHEN, XIAO-DONG WENG, TAO QIU, LIN LIU & HENG-CHENG ZHU. (2014) Ozone oxidative preconditioning inhibits renal fibrosis induced by ischemia and reperfusion injury in rats. Experimental and Therapeutic Medicine 8:6, pages 1764-1768.
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Bing Shen, Xiuheng Liu, Yu Fan & Jianxin Qiu. (2014) Macrophages Regulate Renal Fibrosis Through Modulating TGFβ Superfamily Signaling. Inflammation 37:6, pages 2076-2084.
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Sonali Sonnylal, Shiwen Xu, Helen Jones, Angela Tam, Vivek R. Sreeram, Markella Ponticos, Jill Norman, Pankaj Agrawal, David Abraham & Benoit de Crombrugghe. (2013) Connective Tissue Growth Factor causes EMT-like cell fate changes in vivo and in vitro. Journal of Cell Science.
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Zihua Wang, Jinghong Zhao, Jing Zhang, Jing Wei, Jingbo Zhang & Yunjian Huang. (2010) Protective effect of BMP-7 against aristolochic acid-induced renal tubular epithelial cell injury. Toxicology Letters 198:3, pages 348-357.
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Li Zhou, Ping Fu, Xiao Ru Huang, Fei Liu, Arthur C. K. Chung, Kar Neng LaiHui Yao Lan. (2010) Mechanism of chronic aristolochic acid nephropathy: role of Smad3. American Journal of Physiology-Renal Physiology 298:4, pages F1006-F1017.
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K.G. Dickman & A.P. Grollman. 2010. Comprehensive Toxicology. Comprehensive Toxicology 433 458 .
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