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Journal of Receptors and Signal Transduction Volume 37, 2017 - Issue 5
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Research Article

Tanshinone-induced ERs suppresses IGFII activation to alleviate Ang II-mediated cardiac hypertrophy

Ya-Fang ChenGraduate Institute of Basic Medical Science, China Medical University, Taichung, Taiwan; ;Department of Obstetrics and Gynecology, Taichung Veteran’s General Hospital, Taichung, Taiwan; View further author information
,
Nien-Hung LeeGraduate Institute of Basic Medical Science, China Medical University, Taichung, Taiwan; View further author information
,
Pei-Ying PaiDivision of Cardiology, China Medical University Hospital, Taichung, Taiwan; View further author information
,
Li-Chin ChungDepartment of Hospital and Health Care Administration, Chia Nan University of Pharmacy & Science, Tainan County, Taiwan; View further author information
,
Chia-Yao ShenDepartment of Nursing, MeiHo University, Pingtung, Taiwan; View further author information
,
Peramaiyan RajendranGraduate Institute of Basic Medical Science, China Medical University, Taichung, Taiwan; View further author information
,
Yu-Feng ChenDivision of Cardiology, Department of Internal Medicine, Armed Force Taichung General Hospital, Taichung, Taiwan; View further author information
,
Ray-Jade ChenDepartment of Surgery, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; View further author information
,
Vijaya Padma ViswanadhaDepartment of Biotechnology, Bharathiar University, Coimbatore, India; View further author information
,
Wei-Wen KuoDepartment of Biological Science and Technology, China Medical University, Taichung, Taiwan; View further author information
&
Chih-Yang HuangGraduate Institute of Basic Medical Science, China Medical University, Taichung, Taiwan; ;School of Chinese Medicine, China Medical University, Taichung, Taiwan; ;Department of Health and Nutrition Biotechnology, Asia University, Taichung, TaiwanCorrespondence[email protected]
View further author information
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Pages 493-499 | Received 15 Dec 2016, Accepted 24 Jul 2017, Published online: 16 Aug 2017

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Rui Guo, Lan Li, Jing Su, Sheng Li, Sophia Esi Duncan, Zhihao Liu & Guanwei Fan. (2020) Pharmacological Activity and Mechanism of Tanshinone IIA in Related Diseases. Drug Design, Development and Therapy 14, pages 4735-4748.
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Articles from other publishers (11)

Ye Yang, Mingyan Shao, Wenkun Cheng, Junkai Yao, Lin Ma, Yong Wang & Wei Wang. (2023) A Pharmacological Review of Tanshinones, Naturally Occurring Monomers from Salvia miltiorrhiza for the Treatment of Cardiovascular Diseases. Oxidative Medicine and Cellular Longevity 2023, pages 1-24.
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Aarti Yadav, Surender Singh Yadav, Sandeep Singh & Rajesh Dabur. (2022) Natural products: Potential therapeutic agents to prevent skeletal muscle atrophy. European Journal of Pharmacology 925, pages 174995.
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Xiao Li, Lin Li, Wei Lei, Hui Zi Chua, Zining Li, Xianglong Huang, Qilong Wang, Nan Li & Han Zhang. (2021) Traditional Chinese medicine as a therapeutic option for cardiac fibrosis: Pharmacology and mechanisms. Biomedicine & Pharmacotherapy 142, pages 111979.
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Mohammad Azam Ansari, Farheen Badrealam Khan, Haaris Ahsan Safdari, Ahmad Almatroudi, Mohammad A. Alzohairy, Mohammadreza Safdari, Mehran Amirizadeh, Suriya Rehman, Mohammad Javed Equbal & Mehboob Hoque. (2021) Prospective therapeutic potential of Tanshinone IIA: An updated overview. Pharmacological Research 164, pages 105364.
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Yueh-Min Lin, Khan Farheen Badrealam, Wei-Wen Kuo, Pei Fang Lai, William Shao-Tsu Chen, Cecilia Hsuan Day, Tsung-Jung Ho, Vijaya Padma Viswanadha, Marthandam Asokan Shibu & Chih-Yang Huang. (2021) Nerolidol improves cardiac function in spontaneously hypertensive rats by inhibiting cardiac inflammation and remodelling associated TLR4/ NF-κB signalling cascade. Food and Chemical Toxicology 147, pages 111837.
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Sanah M. Nkadimeng, Christiaan M. L. Steinmann & Jacobus N. Eloff. (2020) Effects and safety of Psilocybe cubensis and Panaeolus cyanescens magic mushroom extracts on endothelin-1-induced hypertrophy and cell injury in cardiomyocytes. Scientific Reports 10:1.
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Tsung‐Jung Ho, Hsi Chin Wu, V. Bharath Kumar, Wei‐Wen Kuo, Yueh‐Shan Weng, Yu‐Lan Yeh, B. Mahalakshmi, Cecilia Hsuan Day, Chi‐Cheng Li & Chih‐Yang Huang. (2020) Danshen ( Salvia miltiorhiza ) inhibits Leu27 IGF‐II ‐induced hypertrophy in H9c2 cells . Environmental Toxicology 35:10, pages 1043-1049.
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Xin Liu, Lin Lin, Qing Li, Yajuan Ni, Chaoying Zhang, Shuguang Qin & Jin Wei. (2019) ERK1/2 communicates GPCR and EGFR signaling pathways to promote CTGF-mediated hypertrophic cardiomyopathy upon Ang-II stimulation. BMC Molecular and Cell Biology 20:1.
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Jie Ren, Li Fu, Shivraj Hariram Nile, Jun Zhang & Guoyin Kai. (2019) Salvia miltiorrhiza in Treating Cardiovascular Diseases: A Review on Its Pharmacological and Clinical Applications. Frontiers in Pharmacology 10.
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Habib Haybar, Saeid Shahrabi, Hadi Rezaeeyan, Reza Shirzad & Najmaldin Saki. (2018) Protective role of heat shock transcription factor 1 in heart failure: A diagnostic approach. Journal of Cellular Physiology 234:6, pages 7764-7770.
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Tunde Barta, Agnes Tosaki, David Haines, Gyorgy Balla, Istvan Lekli & Arpad Tosaki. (2018) Endothelin-1-induced hypertrophic alterations and heme oxygenase-1 expression in cardiomyoblasts are counteracted by beta estradiol: in vitro and in vivo studies. Naunyn-Schmiedeberg's Archives of Pharmacology 391:4, pages 371-383.
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