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Original Article

Effect of uric acid on inflammatory COX-2 and ROS pathways in vascular smooth muscle cells

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Pages 500-505 | Received 10 Mar 2017, Accepted 24 Jul 2017, Published online: 03 Aug 2017

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Segün Doğru, Ekrem Yaşar & Akın Yeşilkaya. (2022) Uric acid can enhance MAPK pathway-mediated proliferation in rat primary vascular smooth muscle cells via controlling of mitochondria and caspase-dependent cell death. Journal of Receptors and Signal Transduction 42:3, pages 293-301.
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Shuo Zhang, Lin Liu, Yu-Qing Huang, Kenneth Lo, Songtao Tang & Ying-Qing Feng. (2020) The association between serum uric acid levels and ischemic stroke in essential hypertension patients. Postgraduate Medicine 132:6, pages 551-558.
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Xiumei Ke, Xuan Yang, Chao Hou, Yunhong Wang, YiFei Zhou, Tongxuan Wu & Rongping Yang. (2024) Preliminary study on the material basis and mechanism underlying uric acid reduction by Thlaspi arvense L.. Journal of Ethnopharmacology 319, pages 116814.
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Xin Sun, Le Yang, Hui Sun, Ye Sun, Shuyun Wei, Ying Han, Wenkai Wang, Ling Kong & Xijun Wang. (2023) TCM and related active compounds in the treatment of gout: the regulation of signaling pathway and urate transporter. Frontiers in Pharmacology 14.
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Yiyuan Zhang, Xiaobao Ding, Lihao Guo, Yanan Zhong, Juan Xie, Yong Xu, Hailun Li & Donghui Zheng. (2023) Comprehensive analysis of the relationship between xanthine oxidoreductase activity and chronic kidney disease. iScience 26:11, pages 107332.
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Haoyi Weng, Haobo Li, Zhu Zhang, Yu Zhang, Linfeng Xi, Di Zhang, Chao Deng, Dingyi Wang, Ruoyan Chen, Gang Chen, Senwei Tang, Xianbo Zuo, Peiran Yang, Zhenguo Zhai & Chen Wang. (2023) Association between uric acid and risk of venous thromboembolism in East Asian populations: a cohort and Mendelian randomization study. The Lancet Regional Health - Western Pacific 39, pages 100848.
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Jen-Chun Wang, Shih-Hung Tsai, Wu-Chien Chien, Chi-Hsiang Chung, Shing-Jong Lin, Yung-Tai Chen & Po-Hsun Huang. (2023) Association between gout and abdominal aortic aneurysm. Journal of Cardiology 82:4, pages 274-278.
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Weidong Liu, Wei Yu, De Xie, Qiang Wang, Hairong Zhao, Jiaming Lv, Furong He, Chenxi Xu, Binyang Chen, Tetsuya Yamamoto, Hidenori Koyama & Jidong Cheng. (2023) High Uric Acid Promotes Atherosclerotic Plaque Instability by Apoptosis Targeted Autophagy. Journal of Atherosclerosis and Thrombosis 30:9, pages 1176-1186.
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Haichao Li, Lihua Wang, Ling Zhang, Jinlei Liu, Hao Zhang, Danyang Wang & Wenqing Yang. (2023) Study on material basis and anti-hypertensive metabolomics of different extraction methods of the Uncaria rhynchophylla Scrophularia Formula. Journal of Pharmaceutical and Biomedical Analysis 233, pages 115464.
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Xiao-Qi Wang, Jiang-Shan Tan, Shu-Yuan Zhang, Wei-li Zhang & Jun Cai. (2023) Asociación del nivel de ácido úrico en suero con los beneficios del control intensivo de la presión arterial. Revista Española de Cardiología 76:8, pages 635-644.
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Xiao-Qi Wang, Jiang-Shan Tan, Shu-Yuan Zhang, Wei-li Zhang & Jun Cai. (2023) Association of serum uric acid with benefits of intensive blood pressure control. Revista Española de Cardiología (English Edition) 76:8, pages 635-644.
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N. A. Kunitskaya, A. L. Ariev & N. N. Kulaeva. (2023) The role of uric acid in the development of infl ammation in kidney disease. Nephrology (Saint-Petersburg) 27:2, pages 39-46.
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Liu YangHao WuCongcong LuoYang ZhaoRongbo DaiZhiqing LiXu ZhangZe GongZeyu CaiYicong ShenFang YuWei LiHongmei ZhaoTao ZhangJunming ZhuYi FuJing Wang & Wei Kong. (2023) Urate-Lowering Therapy Inhibits Thoracic Aortic Aneurysm and Dissection Formation in Mice. Arteriosclerosis, Thrombosis, and Vascular Biology 43:6.
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Bibhas AmatyaSufei YangPeiying YuPedro A.S. Vaz de Castro, Ines ArmandoChunyu ZengRobin A. FelderLaureano D. AsicoPedro A. JoseHewang Lee. (2023) Peroxiredoxin-4 and Dopamine D5 Receptor Interact to Reduce Oxidative Stress and Inflammation in the Kidney. Antioxidants & Redox Signaling.
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Elisa Russo, Maria Bertolotto, Valentina Zanetti, Daniela Picciotto, Pasquale Esposito, Federico Carbone, Fabrizio Montecucco, Roberto Pontremoli, Giacomo Garibotto, Francesca Viazzi & Daniela Verzola. (2023) Role of Uric Acid in Vascular Remodeling: Cytoskeleton Changes and Migration in VSMCs. International Journal of Molecular Sciences 24:3, pages 2960.
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Jen-Chun Wang, Shih-Hung Tsai, Hsiao-Ya Tsai, Shing-Jong Lin & Po-Hsun Huang. (2023) Hyperuricemia exacerbates abdominal aortic aneurysm formation through the URAT1/ERK/MMP-9 signaling pathway. BMC Cardiovascular Disorders 23:1.
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Jing Li, Haifeng Pei, Xianglin Ye, Jing Tian, Haixia Yang, Qing Liu, Xiong Wang & Peng Wang. (2022) Correlation between serum uric acid and coronary collateral circulation in patients with coronary chronic total occlusion. Cardiology Plus 7:4, pages 200-204.
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Xiangming Hu, Jieliang Liu, Wei Li, Chenyang Wang, Guang Li, Yingling Zhou & Haojian Dong. (2022) Elevated serum uric acid was associated with pre-inflammatory state and impacted the role of HDL-C on carotid atherosclerosis. Nutrition, Metabolism and Cardiovascular Diseases 32:7, pages 1661-1669.
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Reyhane Ebrahimi, Parvin Pasalar, Hajar Shokri, Maryam Shabani & Solaleh Emamgholipour. (2022) Evidence for the effect of soluble uric acid in augmenting endoplasmic reticulum stress markers in human peripheral blood mononuclear cells. Journal of Physiology and Biochemistry 78:2, pages 343-353.
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Yousuf Waheed, Fan Yang & Dong Sun. (2021) Role of asymptomatic hyperuricemia in the progression of chronic kidney disease and cardiovascular disease. The Korean Journal of Internal Medicine 36:6, pages 1281-1293.
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Zhipeng Yu, Li Wang, Sijia Wu, Wenjun Xue, Wenzhu Zhao & Jianrong Li. (2021) Potential mechanisms of the anti-hypertensive effects of RVPSL on spontaneously hypertensive rats using non-targeted serum metabolomics. Food & Function 12:18, pages 8561-8569.
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Modi Wang, Riddhi Chaudhuri, Wilson W. S. Ong & Herman O. Sintim. (2021) c-di-GMP Induces COX-2 Expression in Macrophages in a STING-Independent Manner. ACS Chemical Biology 16:9, pages 1663-1670.
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Laurent Savale, Satoshi Akagi, Ly Tu, Amélie Cumont, Raphaël Thuillet, Carole Phan, Benjamin Le Vely, Nihel Berrebeh, Alice Huertas, Xavier Jaïs, Vincent Cottin, Ari Chaouat, Cécile Tromeur, Athénaïs Boucly, Etienne Marie Jutant, Olaf Mercier, Elie Fadel, David Montani, Olivier Sitbon, Marc Humbert, Yuichi Tamura & Christophe Guignabert. (2021) Serum and pulmonary uric acid in pulmonary arterial hypertension. European Respiratory Journal 58:2, pages 2000332.
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Ye Shi, Xiaoqian Zhang, Juan Du, Sipeng Chen, Heng Zhang, Limeng Yang & Zhe Zheng. (2020) Elevated postoperative serum uric acid is associated with major adverse events following coronary artery bypass grafting. Journal of Cardiac Surgery 35:10, pages 2559-2566.
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Arrigo Francesco Giuseppe Cicero, Federica Fogacci & Claudio Borghi. (2020) Uric acid and thrombotic risk: an emerging link. Internal and Emergency Medicine 15:7, pages 1167-1168.
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Nikolas Rapp, Pieter Evenepoel, Peter Stenvinkel & Leon Schurgers. (2020) Uremic Toxins and Vascular Calcification–Missing the Forest for All the Trees. Toxins 12:10, pages 624.
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Mohamed Mohamed Soliman, Mohamed Abdo Nassan, Adil Aldhahrani, Fayez Althobaiti & Wafaa Abdou Mohamed. (2020) Molecular and Histopathological Study on the Ameliorative Impacts of Petroselinum Crispum and Apium Graveolens against Experimental Hyperuricemia. Scientific Reports 10:1.
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Su Woong Jung, Su-Mi Kim, Yang Gyun Kim, Sang-Ho Lee & Ju-Young Moon. (2020) Uric acid and inflammation in kidney disease. American Journal of Physiology-Renal Physiology 318:6, pages F1327-F1340.
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Han Yan, Lanzhou Li, Xue Jiang, Shaopeng Li, Zecheng Chang, Xiaofang Fei & Zhiping Li. (2020) Studies on the Anti-Gouty Arthritis and Anti-hyperuricemia Properties of Astilbin in Animal Models. Open Chemistry 18:1, pages 207-214.
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Jingwei Li, Min Zhao, Xue Jiang, Tingting Liu, Miao Wang & Chunjie Zhao. (2020) Synergistic therapeutic effects of Duzhong Jiangya Tablets and amlodipine besylate combination in spontaneously hypertensive rats using 1 H‐NMR‐ and MS‐based metabolomics . Biomedical Chromatography 34:4.
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Ling Liang, Xianghua Hou, Kevin R. Bainey, Yanlin Zhang, Wayne Tymchak, Zhongquan Qi, Weihua Li & Hoan Linh Banh. (2019) The association between hyperuricemia and coronary artery calcification development: A systematic review and meta‐analysis. Clinical Cardiology 42:11, pages 1079-1086.
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Shaopeng Li, Lanzhou Li, Han Yan, Xue Jiang, Weiwei Hu, Ning Han & Di Wang. (2019) Anti‑gouty arthritis and anti‑hyperuricemia properties of celery seed extracts in rodent models. Molecular Medicine Reports.
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Kaiyou Song, Lianting Li, Guiling Sun & Yanjin Wei. (2018) MicroRNA-381 regulates the occurrence and immune responses of coronary atherosclerosis via cyclooxygenase-2. Experimental and Therapeutic Medicine.
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