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Journal of Receptors and Signal Transduction Volume 38, 2018 - Issue 3
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Research Article

PPARgamma-mediated ALDH1A3 suppression exerts anti-proliferative effects in lung cancer by inducing lipid peroxidation

Tuyen N. M. HuaDepartment of Biochemistry, Wonju College of Medicine, Yonsei University, Wonju, South Korea; ;Department of Global Medical Science, Institute of Lifestyle Medicine, Nuclear Receptor Research Consortium, Mitohormesis Research Center, Wonju College of Medicine, Yonsei University, Wonju, South KoreaView further author information
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Jun NamkungDepartment of Biochemistry, Wonju College of Medicine, Yonsei University, Wonju, South Korea; View further author information
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Ai N. H. PhanDepartment of Biochemistry, Wonju College of Medicine, Yonsei University, Wonju, South Korea; ;Department of Global Medical Science, Institute of Lifestyle Medicine, Nuclear Receptor Research Consortium, Mitohormesis Research Center, Wonju College of Medicine, Yonsei University, Wonju, South KoreaView further author information
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Vu T. A. VoDepartment of Biochemistry, Wonju College of Medicine, Yonsei University, Wonju, South Korea; ;Department of Global Medical Science, Institute of Lifestyle Medicine, Nuclear Receptor Research Consortium, Mitohormesis Research Center, Wonju College of Medicine, Yonsei University, Wonju, South KoreaView further author information
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Min-Kyu KimDepartment of Biochemistry, Wonju College of Medicine, Yonsei University, Wonju, South Korea; ;Department of Global Medical Science, Institute of Lifestyle Medicine, Nuclear Receptor Research Consortium, Mitohormesis Research Center, Wonju College of Medicine, Yonsei University, Wonju, South KoreaView further author information
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Yangsik JeongDepartment of Biochemistry, Wonju College of Medicine, Yonsei University, Wonju, South Korea; ;Department of Global Medical Science, Institute of Lifestyle Medicine, Nuclear Receptor Research Consortium, Mitohormesis Research Center, Wonju College of Medicine, Yonsei University, Wonju, South KoreaCorrespondence[email protected]
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&
Jong-Whan ChoiDepartment of Biochemistry, Wonju College of Medicine, Yonsei University, Wonju, South Korea; Correspondence[email protected]
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Pages 191-197 | Received 08 Jan 2018, Accepted 20 Apr 2018, Published online: 06 Jun 2018

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Kiran Bharat Lokhande, Sangeeta Ballav, Rohit Singh Yadav, K. Venkateswara Swamy & Soumya Basu. (2022) Probing intermolecular interactions and binding stability of kaempferol, quercetin and resveratrol derivatives with PPAR-γ: docking, molecular dynamics and MM/GBSA approach to reveal potent PPAR- γ agonist against cancer. Journal of Biomolecular Structure and Dynamics 40:3, pages 971-981.
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Articles from other publishers (6)

Meghan E. McLean, Maya R. MacLean, Hannah F. Cahill, Raj Pranap Arun, Olivia L. Walker, Marie-Claire D. Wasson, Wasundara Fernando, Jaganathan Venkatesh & Paola Marcato. (2023) The Expanding Role of Cancer Stem Cell Marker ALDH1A3 in Cancer and Beyond. Cancers 15:2, pages 492.
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Shailendra Kumar Gangwar, Aviral Kumar, Kenneth Chun-Hong Yap, Sandra Jose, Dey Parama, Gautam Sethi, Alan Prem Kumar & Ajaikumar B. Kunnumakkara. (2022) Targeting Nuclear Receptors in Lung Cancer—Novel Therapeutic Prospects. Pharmaceuticals 15:5, pages 624.
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Lindsey Kennedy, Vik Meadows, Amelia Sybenga, Jennifer Demieville, Lixian Chen, Laura Hargrove, Burcin Ekser, Wasim Dar, Ludovica Ceci, Debjyoti Kundu, Konstantina Kyritsi, Linh Pham, Tianhao Zhou, Shannon Glaser, Fanyin Meng, Gianfranco Alpini & Heather Francis. (2021) Mast Cells Promote Nonalcoholic Fatty Liver Disease Phenotypes and Microvesicular Steatosis in Mice Fed a Western Diet. Hepatology 74:1, pages 164-182.
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Mingchao Cui, Shaojun Chen, Hanhua Wang, Ping Pan, Yiyuan Luo & Xiuxiu Sha. (2021) Mechanisms of Fritillariae Thunbergii Flos in lung cancer treatment from a systems pharmacology perspective. Journal of Ethnopharmacology 264, pages 113245.
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Jie Song, Wei Zhao, Chang Lu & Xue Shao. (2020) Spliced X‐box binding protein 1 induces liver cancer cell death via activating the Mst1‐JNK‐mROS signalling pathway. Journal of Cellular Physiology 235:12, pages 9378-9387.
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Shuang Nie, Xuetian Qian, Mengyue Shi, Hongzhen Li, Chunyan Peng, Xiwei Ding, Shu Zhang, Bin Zhang, Guifang Xu, Ying Lv, Lei Wang, Helmut Friess, Bo Kong, Xiaoping Zou & Shanshan Shen. (2020) ALDH1A3 Accelerates Pancreatic Cancer Metastasis by Promoting Glucose Metabolism. Frontiers in Oncology 10.
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