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Debate/commentary: Do hormonally active chemicals in the environment pose a significant risk for adverse reproductive effects and cancer?

Do environmental estrogens play a role in development of breast cancer in women and male reproductive problems?

Pages 17-23 | Published online: 02 Dec 2008

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Bo Lü, Ling-fang Jiang & Ping Zhan. (2010) Effects of nonylphenol on ovarian cancer cells PEO4 c-myc and p53 mRNA and protein expression. Toxicological & Environmental Chemistry 92:7, pages 1303-1308.
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J. C. Swart & E. J. Pool. (2009) Development of a Bio-Assay for Estrogens using Estrogen Receptor Alpha Gene Expression by MCF7 Cells as Biomarker. Journal of Immunoassay and Immunochemistry 30:2, pages 150-165.
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Bo Lü & Ping Zhan. (2007) Effects of nonylphenol on the brain cytochrome P450 gene expression in F1 generation rats. Toxicological & Environmental Chemistry 89:3, pages 555-562.
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W. Z. Wu, J. X. Wang, G. F. Zhao & L. You. (2002) THE EMISSION SOOT OF BIOMASS FUELS COMBUSTION AS A SOURCE OF ENDOCRINE DISRUPTERS. Journal of Environmental Science and Health, Part A 37:4, pages 579-600.
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RalphG. Stahl$suffix/text()$suffix/text(). (1997) Can mammalian and non‐mammalian “sentinel species”; data be used to evaluate the human health implications of environmental contaminants?. Human and Ecological Risk Assessment: An International Journal 3:3, pages 329-335.
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Articles from other publishers (27)

Dale W. Rozeboom, Laurie G. Thorp & Jesse E. Nagel. 2019. Encyclopedia of Food and Agricultural Ethics. Encyclopedia of Food and Agricultural Ethics 2031 2039 .
Dale W. Rozeboom, Laurie G. Thorp & Jesse E. Nagel. 2013. Encyclopedia of Food and Agricultural Ethics. Encyclopedia of Food and Agricultural Ethics 1 9 .
Jian Lu, Jun Wu, Peter J. Stoffella & P. Chris Wilson. (2012) Isotope dilution-gas chromatography/mass spectrometry method for the analysis of alkylphenols, bisphenol A, and estrogens in food crops. Journal of Chromatography A 1258, pages 128-135.
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Quincy Teng, Wenlin Huang, Timothy W. Collette, Drew R. Ekman & Chalet Tan. (2008) A direct cell quenching method for cell-culture based metabolomics. Metabolomics 5:2, pages 199-208.
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Jingxian Wang, Ping Xie, Antonius Kettrup & Karl-Werner Schramm. (2005) Evaluation of soot particles of biomass fuels with endocrine-modulating activity in yeast-based bioassay. Analytical and Bioanalytical Chemistry 381:8, pages 1609-1618.
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Sang-Hee Jeong, Byung-Yong Kim, Hwan-Goo Kang, Hyun-Ok Ku & Joon-Hyoung Cho. (2005) Effects of butylated hydroxyanisole on the development and functions of reproductive system in rats. Toxicology 208:1, pages 49-62.
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Sung-Dae Cho, Jin-Hyun Kim, Dae-Yong Kim, Yong-Soon Lee & Kyung-Sun Kang. (2003) Pre-validation study for OECD enhanced test guideline 407 protocol by gavage for 4 weeks using propylthiouracil and tamoxifen. Toxicology Letters 144:2, pages 195-204.
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Toshio Obata. (2002) Role of hydroxyl radical formation in neurotoxicity as revealed by in vivo free radical trapping. Toxicology Letters 132:2, pages 83-93.
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WARREN G. FOSTER & SANJAY K. AGARWAL. (2009) Environmental Contaminants and Dietary Factors in Endometriosis. Annals of the New York Academy of Sciences 955:1, pages 213-229.
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Warren G Foster, Siu Chan, Lawrence Platt & Claude L HughesJrJr. (2002) Detection of phytoestrogens in samples of second trimester human amniotic fluid. Toxicology Letters 129:3, pages 199-205.
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Dal-Ho Han, Hirofumi Tachibana & Koji Yamada. (2001) Inhibition of environmental estrogen-induced proliferation of human breast carcinoma MCF-7 cells by flavonoids. In Vitro Cellular & Developmental Biology - Animal 37:5, pages 275-282.
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DAL-HO HAN, HIROFUMI TACHIBANA & KOJI YAMADA. (2001) INHIBITION OF ENVIRONMENTAL ESTROGEN–INDUCED PROLIFERATION OF HUMAN BREAST CARCINOMA MCF-7 CELLS BY FLAVONOIDS. In Vitro Cellular & Developmental Biology - Animal 37:5, pages 275.
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Toshio Obata & Shunichiro Kubota. (2000) Formation of hydroxy radicals by environmental estrogen-like chemicals in rat striatum. Neuroscience Letters 296:1, pages 41-44.
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Shunichiro Kubota, Sachiko Ohara, Taeko Miyauchi, Tomomi Edo, Eiji Takayama, Kousuke Tomita & Yousuke Seyama. (2000) Effects of para-Nonylphenol on 92 kDa Gelatinase Secretion by Human Peripheral Lymphocytes and U937 Cells in Vitro. Biochemical and Biophysical Research Communications 279:1, pages 270-274.
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I LascombeD BeffaU RüeggJ TarradellasW Wahli. (2000) Estrogenic activity assessment of environmental chemicals using in vitro assays: identification of two new estrogenic compounds.. Environmental Health Perspectives 108:7, pages 621-629.
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Tae-kyu Lim, Masaaki Oyama, Kazunori Ikebukuro & Isao Karube. (2000) Detection of Atrazine Based on the SPR Determination of P450 mRNA Levels in Saccharomyces c erevisiae . Analytical Chemistry 72:13, pages 2856-2860.
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Andreas Kortenkamp & Rolf Altenburger. (1999) Approaches to assessing combination effects of oestrogenic environmental pollutants. Science of The Total Environment 233:1-3, pages 131-140.
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Andreas Kortenkamp & Rolf Altenburger. (1998) Synergisms with mixtures of xenoestrogens: A reevaluation using the method of isoboles. Science of The Total Environment 221:1, pages 59-73.
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C.M. Ardies & C. Dees. (1998) Xenoestrogens significantly enhance risk for breast cancer during growth and adolescence. Medical Hypotheses 50:6, pages 457-464.
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Warren G. Foster. (1998) Agents perturbateurs du système endocrinien et développement de l’appareil reproducteur chez le foetus et chez l’enfant : y a-t-il lieu de s’inquiéter?Endocrine Disruptors and Development of the Reproductive System in the Fetus and Children: Is There Cause for Concern?. Canadian Journal of Public Health 89:S1, pages S41-S46.
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Gerald Ankley, Ellen Mihaich, Ralph Stahl, Donald Tillitt, Theo Colborn, Suzzanne McMaster, Ron Miller, John Bantle, Pamela Campbell, Nancy Denslow, Richard Dickerson, Leroy Folmar, Michael Fry, John Giesy, L. Earl Gray, Patrick Guiney, Thomas Hutchinson, Sean Kennedy, Vincent Kramer, Gerald LeBlanc, Monte Mayes, Alison Nimrod, Reynaldo Patino, Richard Peterson, Richard Purdy, Robert Ringer, Peter Thomas, Les Touart, Glen Van Der Kraak & Tim Zacharewski. (1998) Overview of a workshop on screening methods for detecting potential (anti-) estrogenic/androgenic chemicals in wildlife. Environmental Toxicology and Chemistry 17:1, pages 68-87.
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P. V. M. Shekhar, J. Werdell & V. S. Basrur. (1997) Environmental Estrogen Stimulation of Growth and Estrogen Receptor Function in Preneoplastic and Cancerous Human Breast Cell Lines. JNCI Journal of the National Cancer Institute 89:23, pages 1774-1782.
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D T Zava, M Blen & G Duwe. (1997) Estrogenic activity of natural and synthetic estrogens in human breast cancer cells in culture.. Environmental Health Perspectives 105:suppl 3, pages 637-645.
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C Dees, J S Foster, S Ahamed & J Wimalasena. (1997) Dietary estrogens stimulate human breast cells to enter the cell cycle.. Environmental Health Perspectives 105:suppl 3, pages 633-636.
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Kevin W. Gaido, Linda S. Leonard, Stephanie Lovell, Janet C. Gould, Dariouch Babaı̈, Christopher J. Portier & Donald P. McDonnell. (1997) Evaluation of Chemicals with Endocrine Modulating Activity in a Yeast-Based Steroid Hormone Receptor Gene Transcription Assay. Toxicology and Applied Pharmacology 143:1, pages 205-212.
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Craig Dees, Minoo Askari, James S. Foster, Shamila Ahamed & Jay Wimalasena. (1997) DDT mimicks estradiol stimulation of breast cancer cells to enter the cell cycle. Molecular Carcinogenesis 18:2, pages 107-114.
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Steven F. ArnoldDiane M. KlotzBridgette M. CollinsPeter M. VonierLouis J. GuilletteJr.Jr. & John A. McLachlan. (1996) Synergistic Activation of Estrogen Receptor with Combinations of Environmental Chemicals. Science 272:5267, pages 1489-1492.
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