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Journal of Liquid Chromatography & Related Technologies Volume 29, 2006 - Issue 4
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Original Articles

High Performance Liquid Chromatographic Determination of Ginkgotoxin and Ginkgotoxin‐5′‐Glucoside in Ginkgo Biloba Seeds

Teruki Yoshimura Department of Hygienic Chemistry, Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Hokkaido, Japan
,
Nobuyoshi Udaka Department of Hygienic Chemistry, Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Hokkaido, Japan
,
Junsuke Morita Department of Hygienic Chemistry, Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Hokkaido, Japan
,
Zhang Jinyu Department of Hygienic Chemistry, Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Hokkaido, Japan
,
Keiko Sasaki Department of Hygienic Chemistry, Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Hokkaido, Japan
,
Daisuke Kobayashi Department of Hygienic Chemistry, Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Hokkaido, Japan
,
Keiji Wada Department of Hygienic Chemistry, Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Hokkaido, JapanCorrespondence[email protected]
&
Yasushi Hori Department of Hospital Pharmacy, Niigata City General Hospital, Niigata, Japan
 show all
Pages 605-616 | Received 20 Sep 2005, Accepted 30 Oct 2005, Published online: 06 Feb 2007

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Nan Mei, Xiaoqing Guo, Zhen Ren, Daisuke Kobayashi, Keiji Wada & Lei Guo. (2017) Review of Ginkgo biloba-induced toxicity, from experimental studies to human case reports. Journal of Environmental Science and Health, Part C 35:1, pages 1-28.
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Articles from other publishers (24)

Wen Zhang, Manman Shi, Jiahong Wang, Fuliang Cao & Erzheng Su. (2024) A comprehensive review of ginkgotoxin and ginkgotoxin-5′-glucoside in Ginkgo biloba L. seeds. Journal of Food Composition and Analysis 125, pages 105726.
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Jiarui Cao, Minmin Zou, Wen Zhang, Manman Shi & Erzheng Su. (2023) Investigation of ginkgotoxin in different parts of Ginkgo seeds and its changes during low temperature storage and heating processing. Journal of Food Measurement and Characterization.
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Jinling Chen, Qiqi Wang, Yuting Wu, Yue Wu, Yue Sun, Yunfei Ding, Zhen Wei, Sivakumar Manickam, Saikun Pan, Jie Yang & Yang Tao. (2023) Ultrasound-assisted fermentation of ginkgo kernel juice by Lactiplantibacillus plantarum: Microbial response and juice composition development. Ultrasonics Sonochemistry 99, pages 106587.
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Sullim Lee, Yea Jung Choi, Chen Huo, Akida Alishir, Ki Sung Kang, Il-Ho Park, Taesu Jang & Ki Hyun Kim. (2023) Laricitrin 3-Rutinoside from Ginkgo biloba Fruits Prevents Damage in TNF-α-Stimulated Normal Human Dermal Fibroblasts. Antioxidants 12:7, pages 1432.
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Jie Yang, Yue Sun, Jinling Chen, Yu Cheng, Haoran Zhang, Tengqi Gao, Feng Xu, Saikun Pan, Yang Tao & Jing Lu. (2022) Fermentation of ginkgo biloba kernel juice using Lactobacillus plantarum Y2 from the ginkgo peel: Fermentation characteristics and evolution of phenolic profiles, antioxidant activities in vitro, and volatile flavor compounds. Frontiers in Nutrition 9.
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Yuan Gao, Mengjia Xu, Zhe Zheng, Yiqun Wan, Shihang Wu & Chang Li. (2022) Preparation of ZIF-8 and Its Application in Determination of Pyridoxine and Pyridoxal in Ginkgo Seeds by Ultra-Performance Liquid Chromatography. Foods 11:14, pages 2014.
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Isaac Duah Boateng. (2022) A critical review of current technologies used to reduce ginkgotoxin, ginkgotoxin-5′-glucoside, ginkgolic acid, allergic glycoprotein, and cyanide in Ginkgo biloba L. seed. Food Chemistry 382, pages 132408.
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Han‐Yang Lin, Wen‐Hao Li, Chen‐Feng Lin, Hao‐Ran Wu & Yun‐Peng Zhao. (2022) International Biological Flora: Ginkgo biloba . Journal of Ecology 110:4, pages 951-982.
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Isaac Duah Boateng & Xiao-Ming Yang. (2022) Ginkgo biloba L. seed; A comprehensive review of bioactives, toxicants, and processing effects. Industrial Crops and Products 176, pages 114281.
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Wen Zhang, Manman Shi, Fang Zhang, Fuliang Cao & Erzheng Su. (2021) A Facile Method to Determine the Native Contents of 4′- O -Methylpyridoxine and 4′- O -Methylpyridoxine-5′-glucoside in Ginkgo biloba Seeds . Journal of Agricultural and Food Chemistry 69:47, pages 14270-14277.
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Jin-Peng Zhu, Hao Gong, Faiza Labreche, Xiao-Hong Kou, Cai-E Wu, Gong-Jian Fan, Ting-Ting Li & Jia-Hong Wang. (2021) In vivo toxicity assessment of 4′-O-methylpyridoxine from Ginkgo biloba seeds: Growth, hematology, metabolism, and oxidative parameters. Toxicon 201, pages 66-73.
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Wen Zhang, Minmin Zou, Rong Wu, Huijuan Jiang, Fuliang Cao & Erzheng Su. (2020) Efficient removal of ginkgotoxin from Ginkgo biloba seed powder by combining endogenous enzymatic hydrolysis with resin adsorption . Journal of the Science of Food and Agriculture 101:4, pages 1589-1597.
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Jin-Peng Zhu, Hao Gong, Cai-E Wu, Gong-Jian Fan, Ting-Ting Li & Jia-Hong Wang. (2021) 4′-O-methylpyridoxine: Preparation from Ginkgo biloba Seeds and Cytotoxicity in GES-1 Cells. Toxins 13:2, pages 95.
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Minmin Zou, Wen Zhang, Rong Wu, Huijuan Jiang, Fuliang Cao & Erzheng Su. (2021) Removal of ginkgotoxin from the Ginkgo biloba seeds powder by adopting membrane separation technology. Journal of Cleaner Production 280, pages 124452.
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Hao Gong, Cai-e Wu, Gong-jian Fan, Ting-ting Li, Jia-hong Wang & Tao Wang. (2019) Determination of native contents of 4′-O-methylpyridoxine and its glucoside in raw and heated Ginkgo biloba seeds by high-performance liquid chromatography. Journal of Food Measurement and Characterization 14:2, pages 917-924.
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Wen Zhang, Minmin Zou, Rong Wu, Huijuan Jiang, Fuliang Cao & Erzheng Su. (2019) Insight into the transformation of 4’-O-methylpyridoxine and 4’-O-methylpyridoxine-5’-glucoside in Ginkgo biloba seeds undergoing the heat treatment. Industrial Crops and Products 140, pages 111622.
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Hao Gong, Cai-E. Wu, Xiao-Hong Kou, Gong-Jian Fan, Ting-Ting Li, Jia-Hong Wang & Tao Wang. (2019) Comparison study of 4′-O-methylpyridoxine analogues in Ginkgo biloba seeds from different regions of China. Industrial Crops and Products 129, pages 45-50.
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Daisuke Kobayashi. (2019) Food Poisoning by Ginkgo Seeds through Vitamin B<sub>6</sub> DepletionビタミンB<sub>6</sub>欠乏症を引き起こす銀杏中毒に関する研究. YAKUGAKU ZASSHI 139:1, pages 1-6.
Crossref
Hao Gong, Cai-E Wu, Gong-Jian Fan, Ting-Ting Li, Jia-Hong Wang & Tao Wang. (2018) Determination and Comparison of 4′- O -Methylpyridoxine Analogues in Ginkgo biloba Seeds at Different Growth Stages . Journal of Agricultural and Food Chemistry 66:30, pages 7916-7922.
Crossref
Heung-Bin Lim & Dong-Ho Kim. (2018) Effects of roasting conditions on physicochemical properties and antioxidant activities in Ginkgo biloba seeds. Food Science and Biotechnology 27:4, pages 1057-1066.
Crossref
Timothy R. Baker & Brian T. Regg. (2018) A multi-detector chromatographic approach for characterization and quantitation of botanical constituents to enable in silico safety assessments. Analytical and Bioanalytical Chemistry 410:21, pages 5143-5154.
Crossref
Daisuke Kobayashi, Teruki Yoshimura, Atsushi Johno, Mika Ishikawa, Keiko Sasaki & Keiji Wada. (2015) Decrease in pyridoxal-5′-phosphate concentration and increase in pyridoxal concentration in rat plasma by 4′-O-methylpyridoxine administration. Nutrition Research 35:7, pages 637-642.
Crossref
Daisuke Kobayashi, Teruki Yoshimura, Atsushi Johno, Keiko Sasaki & Keiji Wada. (2011) Toxicity of 4′-O-methylpyridoxine-5′-glucoside in Ginkgo biloba seeds. Food Chemistry 126:3, pages 1198-1202.
Crossref
Teris A. van Beek & Paola Montoro. (2009) Chemical analysis and quality control of Ginkgo biloba leaves, extracts, and phytopharmaceuticals. Journal of Chromatography A 1216:11, pages 2002-2032.
Crossref

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