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Journal of Liquid Chromatography & Related Technologies Volume 33, 2010 - Issue 19
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Original Articles

A LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY METHOD FOR THE SIMULTANEOUS DETERMINATION OF CAPECITABINE, 5′-DEOXY-5-FLUOROCYTIDINE, 5′-DEOXY-5-FLUOROURIDINE, 5-FLUOROURACIL, AND 5-FLUORODIHYDROURACIL IN HUMAN PLASMA

R. Švobaitė Pharmacokinetic Laboratory, Faculty of Pharmacy, University Montpellier I, Montpellier, France; Department of Analytical and Toxicological Chemistry, Kaunas University of Medicine, Kaunas, Lithuania; Oncopharmacology Department, Pharmacy Service, Val d'Aurelle Anticancer Centre, Montpellier, France
,
I. Solassol Oncopharmacology Department, Pharmacy Service, Val d'Aurelle Anticancer Centre, Montpellier, France
,
F. Pinguet Oncopharmacology Department, Pharmacy Service, Val d'Aurelle Anticancer Centre, Montpellier, France
,
T. Mazard Department of Medical Oncology, Val d'Aurelle Anticancer Centre, Montpellier, France
,
L. Ivanauskas Department of Analytical and Toxicological Chemistry, Kaunas University of Medicine, Kaunas, Lithuania
,
M. Ychou Department of Medical Oncology, Val d'Aurelle Anticancer Centre, Montpellier, France
&
F. M. M. Bressolle Pharmacokinetic Laboratory, Faculty of Pharmacy, University Montpellier I, Montpellier, France; Oncopharmacology Department, Pharmacy Service, Val d'Aurelle Anticancer Centre, Montpellier, FranceCorrespondence[email protected]
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Pages 1705-1719 | Published online: 01 Dec 2010

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Hesham Salem, Mohamed A. Mawhoup, Mohamed Sayed & Amany Abdelaziz. (2022) Synchronous Fluorescence Method for Determination of Bevacizumab and Fluorouracil in Laboratory Prepared Mixture, Pharmaceutical Dosage Forms and Spiked Plasma. Analytical Chemistry Letters 12:4, pages 460-472.
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Ning Wang, Ting Wang, Maoling Wang, Aijun Hao & Tiefu Li. (2011) USING ULTRAFILTRATION TO FACILITATE SIMULTANEOUS QUANTIFICATION OF 5-FLUOROURACIL IN MOUSE PLASMA AND TISSUES BY HPLC. Journal of Liquid Chromatography & Related Technologies 34:18, pages 2033-2047.
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Noha F. El Azab, Faizah A. Binjubair, Sara T. Al-Rashood, Sherif Okeil & Noha M. El Zahar. (2022) Simultaneous Quantification of a Neoadjuvant Treatment Used in Locally Advanced Breast Cancer Using an Eco-Friendly UPLC-MS/MS Method: A Pharmacokinetic Study in Rat Plasma. Separations 9:12, pages 403.
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Sagar S. Panda & Ravi Kumar V.V.Bera. (2022) DIFFUSE REFLECTANCE FOURIER TRANSFORM INFRARED SPECTROSCOPIC QUANTIFICATION OF TWO NOVEL DRUGS IN PHARMACEUTICALS: A NEW CASE STUDY FOR CHEMOMETRICS ASSISTED ANALYTICAL PROCEDURE DEVELOPMENT APPROACH. Indian Drugs 59:10, pages 57-65.
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Iliyan Nikolov Kolev, Stanila Seryozheva Stoeva, Ivan Angelov Iliev & Petko Penkov Marinov. (2022) A small-scale method of sample preparation suitable for simultaneous HPLC-UV assay of capecitabine and its 5’-DFCR metabolite in mouse blood plasma. Brazilian Journal of Pharmaceutical Sciences 58.
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Pavel Skvara, Erika Durinikova, Kateřina Grabicová, Erika Mordacikova, Miroslava Matuskova & Andrea Vojs Stanova. (2021) Development of LC-HRMS methods for evaluation of metabolic conversion of 5-fluorocytosine at GDEPT procedure. Journal of Pharmaceutical and Biomedical Analysis 203, pages 114168.
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Jalal Niazi Saei, Ali Mokhtari & Hossein Karimian. (2020) Stopped‐flow chemiluminescence determination of the anticancer drug capecitabine: Application in pharmaceutical analysis and drug‐delivery systems. Luminescence 35:5, pages 797-804.
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Salahaddin Hajizadeh, Khalil Farhadi, Rahim Molaei & Mehrdad Forough. (2020) Silver nanoparticles‐tragacanth gel as a green membrane for effective extraction and determination of capecitabine. Journal of Separation Science 43:13, pages 2666-2674.
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Saeedeh Ansari & Saeed Masoum. (2020) Ultrasound-assisted dispersive solid-phase microextraction of capecitabine by multi-stimuli responsive molecularly imprinted polymer modified with chitosan nanoparticles followed by HPLC analysis. Microchimica Acta 187:6.
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Dhésmon Lima, Giselle Nathaly Calaça, Adriano Gonçalves Viana & Christiana Andrade Pessôa. (2018) Porphyran-capped gold nanoparticles modified carbon paste electrode: a simple and efficient electrochemical sensor for the sensitive determination of 5-fluorouracil. Applied Surface Science 427, pages 742-753.
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Mehrdad Forough, Khalil Farhadi, Rahim Molaei, Hedayat Khalili, Ramin Shakeri, Asghar Zamani & Amir Abbas Matin. (2017) Capillary electrophoresis with online stacking in combination with AgNPs@MCM-41 reinforced hollow fiber solid-liquid phase microextraction for quantitative analysis of Capecitabine and its main metabolite 5-Fluorouracil in plasma samples isolated from cancer patients. Journal of Chromatography B 1040, pages 22-37.
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Barbara Büchel, Peter Rhyn, Stefan Schürch, Claudia Bühr, Ursula Amstutz & Carlo R. Largiadèr. (2012) LC‐MS/MS method for simultaneous analysis of uracil, 5,6‐dihydrouracil, 5‐fluorouracil and 5‐fluoro‐5,6‐dihydrouracil in human plasma for therapeutic drug monitoring and toxicity prediction in cancer patients. Biomedical Chromatography 27:1, pages 7-16.
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