DEVELOPMENT AND VALIDATION OF AN UPLC METHOD FOR THE RAPID SEPARATION OF POSITIONAL ISOMERS AND POTENTIAL IMPURITIES OF RIVASTIGMINE HYDROGEN TARTRATE IN DRUG SUBSTANCE AND DRUG PRODUCT

T. Satyanarayana Raju Dr. Reddy's Laboratories Ltd. Active Pharmaceutical Ingredients, Hyderabad, India; Department of Chemistry, University College of Engineering, Osmania University, Hyderabad, IndiaCorrespondence[email protected] [email protected]

L. Kalyanaraman Dr. Reddy's Laboratories Ltd. Active Pharmaceutical Ingredients, Hyderabad, India

V. Venkat Reddy Dr. Reddy's Laboratories Ltd. Active Pharmaceutical Ingredients, Hyderabad, India

P. Yadagiri Swamy Department of Chemistry, University College of Engineering, Osmania University, Hyderabad, India

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Nam Sook Kim, Hwan Seong Choi, Sol A Yeon, Hyemin Bae, Hyungil Kim & Cho Sooyeul. (2023) Simultaneous determination of 11 nootropic substances potentially adulterated in dietary supplements for improving brain function using ultra-performance liquid chromatography and liquid chromatography–quadrupole-time-of-flight mass spectrometry. Food Additives & Contaminants: Part A 40:7, pages 797-811.
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Ravsaheb H. Rathod, Suraj R. Chaudhari, Amod S. Patil & Atul A. Shirkhedkar. (2019) Ultra-high performance liquid chromatography-MS/MS (UHPLC-MS/MS) in practice: analysis of drugs and pharmaceutical formulations. Future Journal of Pharmaceutical Sciences 5:1.
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Naz Hasan Huda, Bhawna Gauri, Heather A. E. Benson & Yan Chen. (2018) A Stability Indicating HPLC Assay Method for Analysis of Rivastigmine Hydrogen Tartrate in Dual-Ligand Nanoparticle Formulation Matrices and Cell Transport Medium. Journal of Analytical Methods in Chemistry 2018, pages 1-10.
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Mehmet Gumustas, Sevinc Kurbanoglu, Bengi Uslu & Sibel A. Ozkan. (2013) UPLC versus HPLC on Drug Analysis: Advantageous, Applications and Their Validation Parameters. Chromatographia 76:21-22, pages 1365-1427.
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DEVELOPMENT AND VALIDATION OF AN UPLC METHOD FOR THE RAPID SEPARATION OF POSITIONAL ISOMERS AND POTENTIAL IMPURITIES OF RIVASTIGMINE HYDROGEN TARTRATE IN DRUG SUBSTANCE AND DRUG PRODUCT

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DEVELOPMENT AND VALIDATION OF AN UPLC METHOD FOR THE RAPID SEPARATION OF POSITIONAL ISOMERS AND POTENTIAL IMPURITIES OF RIVASTIGMINE HYDROGEN TARTRATE IN DRUG SUBSTANCE AND DRUG PRODUCT

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